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Multifocal biliary carcinoma; whether synchronous or metastatic: A need to conquer 多灶性胆道癌;无论是同步的还是转移的:需要征服
IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-06-15 DOI: 10.18231/j.jdpo.2023.027
Anju Shukla, Fatema Shareh Naqvi, Shashank Chaudhary
{"title":"Multifocal biliary carcinoma; whether synchronous or metastatic: A need to conquer","authors":"Anju Shukla, Fatema Shareh Naqvi, Shashank Chaudhary","doi":"10.18231/j.jdpo.2023.027","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.027","url":null,"abstract":"Multiple synchronous primary carcinoma involving gall bladder, liver and common bile duct are rare and difficult to differentiate with hepatic and extrahepatic bile duct metastasis from single primary. Radiological features, molecular landscape, and even integrated mutational profiling are not of much help. We describe a case of 48-year-old male who presented with jaundice and follow up CT scan raised the suspicion of gall bladder carcinoma with hepatic metastasis. Peroperative frozen section examination revealed adenocarcinoma with involvement of cystic duct margin; however revised common duct margin was free from tumor invasion. Final histopathology on resected gall bladder revealed multifocal adenocarcinoma, while histomorphology of hepatic nodule was consistent with cholangiocarcinoma. Common bile duct a one focus had also revealed adenocarcinoma while cut margins were negative form malignancy. In view of different morphology of gall bladder and hepatic tumor, no continuity of three tumors and single large, firm, non umblicated hepatic nodule, diagnosis of multiple synchronous carcinoma was suggested.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115327370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An unusually extensive orthokeratinized odontogenic cyst: A case report 异常广泛的形角化牙源性囊肿1例报告
IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-06-15 DOI: 10.18231/j.jdpo.2023.026
S. Sachdev, Y. Adhane, M. A. Sardar, Priyanka Gajare, T. Chettiankandy
{"title":"An unusually extensive orthokeratinized odontogenic cyst: A case report","authors":"S. Sachdev, Y. Adhane, M. A. Sardar, Priyanka Gajare, T. Chettiankandy","doi":"10.18231/j.jdpo.2023.026","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.026","url":null,"abstract":"While odontogenic keratocysts (OKC) are fairly common and well-known, orthokeratinized odontogenic cysts (OOCs) are quite rare accounting for less than 1% of odontogenic cysts. The entity is characterized by the presence of a predominant orthokeratinized lining. OOC is much less aggressive as compared to OKC and simple enucleation is discerned as adequate treatment with minimal chances of recurrence. The present case report describes an extensive OOC that involved most of the angle and ramus of the mandible in a 25-year-old female.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123157080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Breast hamartoma: A case series of 4 hamartoma cases including a rare myoid hamartoma of male breast 乳房错构瘤:报告4例错构瘤，包括一例罕见的男性乳房肌样错构瘤
IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-06-15 DOI: 10.18231/j.jdpo.2023.028
D. Cherian, M. Siddiqui, S. Dhule, Piyush Prakash Narkhede, T. Fatima
{"title":"Breast hamartoma: A case series of 4 hamartoma cases including a rare myoid hamartoma of male breast","authors":"D. Cherian, M. Siddiqui, S. Dhule, Piyush Prakash Narkhede, T. Fatima","doi":"10.18231/j.jdpo.2023.028","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.028","url":null,"abstract":"Hamartomas by definition are masses of disorganised mature tissue indigenous to the particular site. They are seen in anatomical sites like skin, spleen and lungs where the latter is the most common site. Breast hamartomas are benign lesions not that commonly encountered in clinical practice. It is also synonymously known by other terms like adenolipoma. Terms like fibroadenolipoma and adenolipofibroma which were previously used are not recommended by the WHO. Hamartomas of the breast are composed of fibrous glandular or fat tissue. Breast hamartomas are rare in females and rarest in males. We report 4 cases of breast hamartomas one of which was myoid hamartoma in 38-year-old male and hamartoma with PASH (pseudoaangiomatous stromal hyperplasia) in a 32 year old female.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131663212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gaucher’s disease is a common storage disorder but rare entity: Two case report 戈谢病是一种常见的存储障碍，但罕见的实体:2例报告
IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-06-15 DOI: 10.18231/j.jdpo.2023.029
K. K. Verma, Nighat Hussain
{"title":"Gaucher’s disease is a common storage disorder but rare entity: Two case report","authors":"K. K. Verma, Nighat Hussain","doi":"10.18231/j.jdpo.2023.029","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.029","url":null,"abstract":"Gaucher's disease is a rare, inherited autosomal recessive metabolic disorder due to deficiency of enzyme Glucocerebrosidase resulting in deposition of glucosylceramide. Deposition of glucosylceramide in different organs causes dysfunction and is responsible for specific systemic symptoms and signs. In the present cases, the first case was a 24-year-old female who presented with severe weakness with abdominal fullness due to massive splenomegaly. The unicity of the case was anti-nuclear antibody positivity. Although clinical signs and symptoms were classical in this case. The second case was a 20-year-old male who was already diagnosed case of Gaucher's disease but the only complaint was abdominal fullness due to massive splenomegaly. Special stains were play a tremendous role to highlighting Gaucher's cells.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127451544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neurofibroma of Adrenal gland- A rare case report 肾上腺神经纤维瘤1例报告
IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-06-15 DOI: 10.18231/j.jdpo.2023.022
Ankita N, Nagarekha K, M. Shanthi, Patil Shashirekha
{"title":"Neurofibroma of Adrenal gland- A rare case report","authors":"Ankita N, Nagarekha K, M. Shanthi, Patil Shashirekha","doi":"10.18231/j.jdpo.2023.022","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.022","url":null,"abstract":"Neurofibroma of the adrenal glands is rare, most common site of presentation are head and neck region and along the nerves. With the us of computed tomography , magnetic resonance imaging , an ultrasonography for the detection of adrenals masses is increasing. On computed tomography neurogenic tumours frequently appear as a distinct, smooth or lobulated mass. All varieties of neurogenic tumours may exhibit calcification But for confirmation of the lesion histopathological examination and immunohistochemistry is a must. Neurofibroma of adrenals although rare but a possibility. Immunohistochemistry plays an important role in confirming the diagnosis. IHC helps in definitive diagnosis which helps clinicians with management of the patient.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128165503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A retrospective study on cervical cancer screening- In a newly opened tertiary care Centre in Eastern India 子宫颈癌筛查的回顾性研究-在印度东部新开设的三级保健中心
IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-06-15 DOI: 10.18231/j.jdpo.2023.018
R. Saha, Deepika Pandey, S. Mondal, T. Santosh, Sujaya Mazumder, I. Chakrabarti
{"title":"A retrospective study on cervical cancer screening- In a newly opened tertiary care Centre in Eastern India","authors":"R. Saha, Deepika Pandey, S. Mondal, T. Santosh, Sujaya Mazumder, I. Chakrabarti","doi":"10.18231/j.jdpo.2023.018","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.018","url":null,"abstract":": One of the most prevalent cancers, cervical cancer is also the leading cause of mortality for women in underdeveloped nations. A fundamental test for finding infections and precancerous diseases is the Papanicolaou smear. This study aims to comprehend the function of cervical screening in detecting premalignant, malignant, and non-neoplastic lesions as well as the prevalence of different lesions in women who received a traditional pap smear technique. We screened women in the age group of 15-70 years who attended the Outpatient department of the Obstetrics and Gynaecology department of AIIMS, Kalyani. All women who gave consent for screening by Pap smear test were included. Of 2133 cases, most of the cases were benign comprising of Negative for Intraepithelial Lesion or malignancy (NILM) of about 1989 (93.24%) cases, 705 (33.05%) inflammatory. Atypical squamous cells of undetermined significance in 44 cases (2.06%), Atypical squamous cells cannot exclude HSIL in 3 (0.14%), low-grade squamous intraepithelial lesion (LSIL) in 11 (0.52%), high-grade squamous intraepithelial lesion (HSIL) in 5 (0.23%) women and Atypical glandular cell in 7 (0.33%). Out of 202 asymptomatic women (9.47%), 12 cases (0.56%) showed epithelial cell abnormality (8 ASCUS, 2 LSIL, 1 ASCH, 1HSIL) (Odds ratio=0.5056, Significance level, P=0.0362). Conventional Pap smear test is a very easy and cheap diagnostic tool to detect premalignant, malignant, and non-neoplastic lesions and the prevalence of various lesions.  As per the American Cancer Society (ACS), a pap smear should start from 25 years to be done till 65 years (repeated after every 3 years).","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123287756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Appendiceal collision tumor presented as acute appendicitis: A dissonant scenario 阑尾碰撞肿瘤表现为急性阑尾炎:一个不和谐的场景
IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-06-15 DOI: 10.18231/j.jdpo.2023.020
Sushma Prasanthi Nagireddi, R. Shetty, Athira K P, Madhukar Devadiga, K. Vaidya
{"title":"Appendiceal collision tumor presented as acute appendicitis: A dissonant scenario","authors":"Sushma Prasanthi Nagireddi, R. Shetty, Athira K P, Madhukar Devadiga, K. Vaidya","doi":"10.18231/j.jdpo.2023.020","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.020","url":null,"abstract":"Renal cell carcinoma arises from the epithelium of the renal tubules and accounts for approximately 3% of adult malignancies. Tumours occur most often in older individuals usually in sixth and seventh decades of life. Bilateral multifocal papillary type of RCC is rare and its presence should prompt the suspicion of some underlying hereditary genetic predisposition thus thorough cytogenetic evaluation and detailed family history could help in finding the etiology. Bilateral RCC could be synchronous or metachronous. We hereby present the autopsy findings of a case of sudden death of a 65 years old male. On histopathological evaluation, both kidneys showed papillary variant of renal cell carcinoma as an incidental finding.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126770102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metaplastic squamous cell carcinoma caricaturing as tuberculous mastitis-A vicissitude of clinical diagnostic misadventure 被讽刺为结核性乳腺炎的化生性鳞状细胞癌——临床诊断失误的变迁
IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-06-15 DOI: 10.18231/j.jdpo.2023.021
K. Pardeshi, Hoogar Mallinath Basalingappa, Sameer Kadam, Nakul Y. Sampat, Vaishali Bhonsle, Arvind Govind Valand
{"title":"Metaplastic squamous cell carcinoma caricaturing as tuberculous mastitis-A vicissitude of clinical diagnostic misadventure","authors":"K. Pardeshi, Hoogar Mallinath Basalingappa, Sameer Kadam, Nakul Y. Sampat, Vaishali Bhonsle, Arvind Govind Valand","doi":"10.18231/j.jdpo.2023.021","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.021","url":null,"abstract":"Tuberculous mastitis and invasive breast cancers are known to co-exist or occur in the breast independently of each other, albeit the former being less common in developed countries. Tuberculous mastitis with its clinical presentation and morphological features can caricature invasive breast carcinoma. The overlapping features of tuberculous mastitis and metaplastic squamous cell carcinoma often lead to, if no due clinical diligence and discretion is used, bewildering misinterpretation with the vicissitude of diagnostic implications of tuberculous mastitis ensuing catastrophic and perilous ramifications. A 42-year-old woman presented with exophytic growth with extensive areas of ulceration. Clinically, the lesion was diagnosed as disseminated tuberculous mastitis based on clinical and morphological features, which was surgically resected. On histological examination, the lesion was diagnosed as invasive metaplastic squamous cell carcinoma. Thecase being presented here displays the vagary involved in clinical diagnosis of tuberculous mastitis inasmuch as it often shares clinical and morphological features with a devastatingly perilous variant of invasive duct carcinoma, metaplastic squamous cell carcinoma, the inadvertent eschewing of or misapprehending of which may engender devastating prognostic implications.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129540763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral multifocal papillary renal cell carcinoma on autopsy: A case report 双侧多灶性乳头状肾细胞癌尸检报告1例
IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-06-15 DOI: 10.18231/j.jdpo.2023.019
Monika Yadav, R. Agarwal, Kulwant Singh, Yogesh Kumar, Bharat B Sidana
{"title":"Bilateral multifocal papillary renal cell carcinoma on autopsy: A case report","authors":"Monika Yadav, R. Agarwal, Kulwant Singh, Yogesh Kumar, Bharat B Sidana","doi":"10.18231/j.jdpo.2023.019","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.019","url":null,"abstract":"Renal cell carcinoma arises from the epithelium of the renal tubules and accounts for approximately 3% of adult malignancies. Tumours occur most often in older individuals usually in sixth and seventh decades of life. Bilateral multifocal papillary type of RCC is rare and its presence should prompt the suspicion of some underlying hereditary genetic predisposition thus thorough cytogenetic evaluation and detailed family history could help in finding the etiology. Bilateral RCC could be synchronous or metachronous. We hereby present the autopsy findings of a case of sudden death of a 65 years old male. On histopathological evaluation, both kidneys showed papillary variant of renal cell carcinoma as an incidental finding.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130764565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An incidental finding of microfilaria on a urine cytological smear study 尿细胞学涂片检查偶然发现微丝蚴
IP Journal of Diagnostic Pathology and Oncology Pub Date : 2023-06-15 DOI: 10.18231/j.jdpo.2023.025
Patel Keval A, Parmar Riddhi A
{"title":"An incidental finding of microfilaria on a urine cytological smear study","authors":"Patel Keval A, Parmar Riddhi A","doi":"10.18231/j.jdpo.2023.025","DOIUrl":"https://doi.org/10.18231/j.jdpo.2023.025","url":null,"abstract":"In developing nations, lymphatic filariasis is a significant public health concern. Wuchereria bancrofti species, which are morphologically recognised as sheathed parasites with a tail tip free of nuclei, are responsible for almost 90% of the cases in India. Microfilariae have been found in a wide range of other body fluids as well as urine samples from patients with chylous and achylous hematuria. We report a case of microfilariasis in urine cytology. This study aims to raise awareness of the possibility of filariasis in bodily fluids and aspirates, particularly in areas where it is endemic. Identification results in a comprehensive diagnostic and treatment plan for the patient.","PeriodicalId":364340,"journal":{"name":"IP Journal of Diagnostic Pathology and Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133918075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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