Current Physical Medicine and Rehabilitation Reports最新文献_第3页

Dysphagia in Parkinson Disease: Part I - Pathophysiology and Diagnostic Practices. 帕金森病的吞咽困难:第一部分-病理生理学和诊断实践。

IF 1.1

Current Physical Medicine and Rehabilitation Reports Pub Date : 2023-06-01 Epub Date: 2023-03-28 DOI: 10.1007/s40141-023-00392-9

Denis Michael Rudisch, Maryann N Krasko, Ryan Burdick, Courtney K Broadfoot, Nicole Rogus-Pulia, Michelle R Ciucci

{"title":"Dysphagia in Parkinson Disease: Part I - Pathophysiology and Diagnostic Practices.","authors":"Denis Michael Rudisch, Maryann N Krasko, Ryan Burdick, Courtney K Broadfoot, Nicole Rogus-Pulia, Michelle R Ciucci","doi":"10.1007/s40141-023-00392-9","DOIUrl":"10.1007/s40141-023-00392-9","url":null,"abstract":"Purpose of review: Dysphagia affects the majority of individuals with Parkinson disease (PD) and is not typically diagnosed until later in disease progression. This review will cover the current understanding of PD pathophysiology, and provides an overview of dysphagia in PD including diagnostic practices, gaps in knowledge, and future directions.Recent findings: Many non-motor and other motor signs of PD appear in the prodrome prior to the manifestation of hall- mark signs and diagnosis. While dysphagia often presents already in the prodrome, it is not routinely addressed in standard neurology examinations.Summary: Dysphagia in PD can result in compromised efficiency and safety of swallowing, which significantly contributes to malnutrition and dehydration, decrease quality of life, and increase mortality. The heterogeneous clinical presentation of PD complicates diagnostic procedures which often leads to delayed treatment. Research has advanced our knowledge of mechanisms underlying PD, but dysphagia is still largely understudied, especially in the prodromal stage.","PeriodicalId":36406,"journal":{"name":"Current Physical Medicine and Rehabilitation Reports","volume":"11 2","pages":"176-187"},"PeriodicalIF":1.1,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10441627/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10060906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dysphagia in Parkinson Disease: Part II-Current Treatment Options and Insights from Animal Research. 帕金森病的吞咽困难：第二部分——目前的治疗选择和动物研究的见解

IF 1

Current Physical Medicine and Rehabilitation Reports Pub Date : 2023-06-01 Epub Date: 2023-04-24 DOI: 10.1007/s40141-023-00393-8

Maryann N Krasko, Denis Michael Rudisch, Ryan J Burdick, Nicole E Schaen-Heacock, Courtney K Broadfoot, Alex F Nisbet, Nicole Rogus-Pulia, Michelle R Ciucci

{"title":"Dysphagia in Parkinson Disease: Part II-Current Treatment Options and Insights from Animal Research.","authors":"Maryann N Krasko, Denis Michael Rudisch, Ryan J Burdick, Nicole E Schaen-Heacock, Courtney K Broadfoot, Alex F Nisbet, Nicole Rogus-Pulia, Michelle R Ciucci","doi":"10.1007/s40141-023-00393-8","DOIUrl":"10.1007/s40141-023-00393-8","url":null,"abstract":"Purpose of review: Dysphagia is highly prevalent in Parkinson disease (PD) but is not typically identified nor treated until later in the disease process. This review summarizes current pharmacological, surgical, and behavioral treatments for PD-associated dysphagia and contributions from translational animal research.Recent findings: Swallowing is a complex physiologic process controlled by multiple brain regions and neurotransmitter systems. As such, interventions that target nigrostriatal dopamine dysfunction have limited or detrimental effects on swallowing outcomes. Behavioral interventions can help target PD-associated dysphagia in mid-to-late stages. Animal research is necessary to refine treatments and useful in studying prodromal dysphagia.Summary: Dysphagia is an early, common, and debilitating sign of PD. Current pharmacological and surgical interventions are not effective in ameliorating swallowing dysfunction; behavioral intervention remains the most effective approach for dysphagia treatment. Animal research has advanced our understanding of mechanisms underlying PD and PD-associated dysphagia, and continues to show translational promise for the study of dysphagia treatment options.","PeriodicalId":36406,"journal":{"name":"Current Physical Medicine and Rehabilitation Reports","volume":"1 1","pages":"188-198"},"PeriodicalIF":1.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11411792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42930392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abdominal Wall Muscle Injuries in Athletes 运动员腹壁肌肉损伤

IF 1.1

Current Physical Medicine and Rehabilitation Reports Pub Date : 2023-05-29 DOI: 10.1007/s40141-023-00402-w

Michelle Copley, Stephen I. Johnson

引用次数: 0

Update on Interventional Procedural Considerations for Tendinopathy 肌腱疾病介入手术注意事项的最新进展

IF 1.1

Current Physical Medicine and Rehabilitation Reports Pub Date : 2023-05-26 DOI: 10.1007/s40141-023-00401-x

M. LaCourse, Mani Singh, Jennifer Soo Hoo

引用次数: 0

Role of Stem Cells for Knee Cartilage Injuries in Athletes 干细胞在运动员膝关节软骨损伤中的作用

IF 1.1

Current Physical Medicine and Rehabilitation Reports Pub Date : 2023-05-24 DOI: 10.1007/s40141-023-00404-8

Douglas Bryant, Paige Chase, Devon Shannon, Stephen Schaaf

引用次数: 0

Hydrodissection of Peripheral Nerve Entrapments 周围神经压迫的水解剖

IF 1.1

Current Physical Medicine and Rehabilitation Reports Pub Date : 2023-05-20 DOI: 10.1007/s40141-023-00405-7

C. Nicolosi, Joshay A. Ford, A. Meron

引用次数: 1

Pathophysiology of Radiation Fibrosis Syndrome 辐射性纤维化综合征的病理生理学

IF 1.1

Current Physical Medicine and Rehabilitation Reports Pub Date : 2023-05-16 DOI: 10.1007/s40141-023-00403-9

Cristina Kline-Quiroz, Hayden Byrd, J. Dovgan, N. Lockney

引用次数: 0

Evaluation and Management of Carpal Instability 腕关节不稳定性的评估与管理

IF 1.1

Current Physical Medicine and Rehabilitation Reports Pub Date : 2023-05-02 DOI: 10.1007/s40141-023-00400-y

Ryan J. Wei, J. E. Gardner, Stephen Schaaf, J. Hill, Zachary P. Bailowitz

引用次数: 0

Platelet-Rich Plasma Versus Corticosteroid Injection in the Treatment of Arthropathic Chronic Low Back Pain: Systematic Review and Meta-analysis 富血小板血浆与皮质类固醇注射治疗关节病慢性腰痛:系统回顾和荟萃分析

IF 1.1

Current Physical Medicine and Rehabilitation Reports Pub Date : 2023-05-01 DOI: 10.1007/s40141-023-00399-2

Elver S. Ho, Anusha Lekshminarayanan, A. Tom, M. Khalil, Yungtai Lo, S. Agarwal, Derek J. Ho

引用次数: 0

The Development of Modern Radiation Therapy 现代放射治疗的发展

IF 1.1

Current Physical Medicine and Rehabilitation Reports Pub Date : 2023-04-29 DOI: 10.1007/s40141-023-00395-6

K. Lapen, Y. Yamada

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