International Journal of Clinical Pharmacokinetics and Medical Sciences最新文献_第2页

Case Report on Henoch-Schonlein Purpura Vasculitis 过敏性紫癜性血管炎1例报告

International Journal of Clinical Pharmacokinetics and Medical Sciences Pub Date : 2023-04-21 DOI: 10.26452/ijcpms.v3i2.503

M. M, R. George, Manaswi N, Ashik P T, Thasvin U R

{"title":"Case Report on Henoch-Schonlein Purpura Vasculitis","authors":"M. M, R. George, Manaswi N, Ashik P T, Thasvin U R","doi":"10.26452/ijcpms.v3i2.503","DOIUrl":"https://doi.org/10.26452/ijcpms.v3i2.503","url":null,"abstract":"Henoch-Schonlein purpura is a type III hypersensitivity leukocytoclastic small vessel vasculitis caused by the IgA-immune complex that primarily affects children and has the potential to escalate to many complications. A female patient of age 17 years came with the complaint of asymptomatic red rashes over their left lower leg since 3 weeks back. It soon involved the other leg within 3-4 days. Also Associated ankle pain. on clinical examination Pulse Rate-86/min, BP-120/80 mm/Hg, RR-20/minute, non-pitting edema and palpable purpura of bilateral lower legs and few over the thighs. skin biopsy was done, also received fresh tissue for IF, which shows 1-granular IgA along upper dermal vessels, she was given Tab. Augmentin 625mg, Tab. Colchicine 500 mcg, Mupimet ointment and other supportive measures for two days. When the patient's condition improved, discharged with medication Tab. Augmentin 625mg, Tab. pantoprazole 40mg, Mupimet ointment each for 4 days and Tab. colchicine 500mcg for 7 days with advice to review in dermatology OPD and rheumatology OPD with prior appointment after one week. Continued collaboration and knowledge-sharing within the medical community will ultimately improve patient outcomes and contribute to the advancement of care for individuals affected by this rare vasculitis disorder.","PeriodicalId":363324,"journal":{"name":"International Journal of Clinical Pharmacokinetics and Medical Sciences","volume":"46 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133699219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case Report on Myxedema Coma Associated with End-Stage Cardiac Disease 终末期心脏病伴黏液水肿昏迷1例报告

International Journal of Clinical Pharmacokinetics and Medical Sciences Pub Date : 2023-04-19 DOI: 10.26452/ijcpms.v3i2.501

R. a, Niharika K J, Ravindra B N, R. George

{"title":"Case Report on Myxedema Coma Associated with End-Stage Cardiac Disease","authors":"R. a, Niharika K J, Ravindra B N, R. George","doi":"10.26452/ijcpms.v3i2.501","DOIUrl":"https://doi.org/10.26452/ijcpms.v3i2.501","url":null,"abstract":"Myxedema coma is a critical disorder with high mortality rates. Disruption of the compensatory mechanism for severe and long-term hypothyroidism by various causes leads to serious complications, including hypothermia, respiratory failure, circulatory failure, and central nervous system dysfunction. The most common causes of myxedema coma are thought to include infectious disease, stroke, myocardial infarction, sedative medicines, exposure to the cold and surgery in patients with poorly controlled hypothyroidism. We present a case of an 82-year-old female presented with complaints of loss of speech for 3 days, complaint of easy fatiguability for 3 days, altered sensorium since 1 day, weakness of both upper and lower limbs for 3 days and the patient attenders complaint of that patient is not taking food and difficult in swallowing since 3 days. In spite of the foregoing, patients with decreased mental status who have undergone thyroid surgery or hypothyroidism should be evaluated for myxedema coma. Additionally, this condition may be caused on by chronic hypothyroidism or by experiencing acute precipitating events like sepsis, a cerebrovascular accident, gastrointestinal bleeding, exposure to cold, trauma, or taking certain medications. A high mortality rate was noted, so patients whose myxedema coma is suspected should start receiving treatment right away.","PeriodicalId":363324,"journal":{"name":"International Journal of Clinical Pharmacokinetics and Medical Sciences","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132435853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Good Storage and Good Distribution Practices of Pharmaceuticals In India and the USA With Regulatory Enforcement 印度和美国药品的良好储存和良好分销规范与监管执法

International Journal of Clinical Pharmacokinetics and Medical Sciences Pub Date : 2023-02-10 DOI: 10.26452/ijcpms.v3i1.495

S. Sushanth Kumar, Bommireddy Srilekha

引用次数: 0

Dostarlimab as a Miracle Drug Dostarlimab是一种神奇的药物

International Journal of Clinical Pharmacokinetics and Medical Sciences Pub Date : 2023-02-06 DOI: 10.26452/ijcpms.v3i1.493

Dinesh Kumar Banduchode, K. Varshith, Shaikh Sana, Vallarasu M, Vallivedu Tejamahi

{"title":"Dostarlimab as a Miracle Drug","authors":"Dinesh Kumar Banduchode, K. Varshith, Shaikh Sana, Vallarasu M, Vallivedu Tejamahi","doi":"10.26452/ijcpms.v3i1.493","DOIUrl":"https://doi.org/10.26452/ijcpms.v3i1.493","url":null,"abstract":"According to The and How, the squamous cell is the leading cause of mortality worldwide, with financial reporting almost 80 percent of fatal crashes through 2020 and nearly one in every six lost lives (who). Chest (2.26 million instances), respiratory system (2.21 million cases), rectum and anus (1.93 million cases), along with bladder carcinoma cells, might be the most prevalent carcinoma cells through 2019 - 20 (1.41 million cases). Someone pd-1 therapeutic monoclonal labelled dostarlimb (jumper) seems to have been advantageous within the care of patients as well as testicular Cancer who had encouraged but rather reoccurring illnesses which would be homologous recombination suffering from a lack (dmmr) and those that have continued to advance both during known strategies with that kind of a silver-gold training regime. Someone 100% (95% ci, 74%-100%) diagnostic comprehensive response percentage had been accomplished for adjuvant therapy dostarlimb through 12 patients receiving this same officer, such as six months. Investigation and detection mentioned that the average duration between vaginal M.R.I. has been 16 days (range, 8-26), and the average time complete colonoscopy has been 20 days (range, 14-28) publish dostarlimb. In this overview, we provide straightforward pharmacologic and toxicokinetic information regarding this same material towards the wellness–treatment gang even though humans assume it would be just an easy reference moment in time through the case of emergency information - searching.","PeriodicalId":363324,"journal":{"name":"International Journal of Clinical Pharmacokinetics and Medical Sciences","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125773124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Formulation and evaluation of bio compounds of berberis aristata compressed tablets in psoriasis treatment 小檗压缩片生物化合物治疗银屑病的配方及评价

International Journal of Clinical Pharmacokinetics and Medical Sciences Pub Date : 2022-12-23 DOI: 10.26452/ijcpms.v2i4.483

Kishore Bandarapalle

引用次数: 0