Technical Innovations and Patient Support in Radiation Oncology最新文献

{"title":"Patient expectation and experience of MR-guided radiotherapy using a 1.5T MR-Linac","authors":"S.R. de Mol van Otterloo ,&nbsp;J.M. Westerhoff ,&nbsp;T. Leer ,&nbsp;R.H.A. Rutgers ,&nbsp;L.T.C. Meijers ,&nbsp;L.A. Daamen ,&nbsp;M.P.W. Intven ,&nbsp;H.M. Verkooijen","doi":"10.1016/j.tipsro.2023.100224","DOIUrl":"https://doi.org/10.1016/j.tipsro.2023.100224","url":null,"abstract":"<div><h3>Background and Purpose</h3><p>Online adaptive MR-guided radiotherapy (MRgRT) is a relatively new form of radiotherapy treatment, delivered using a MR-Linac. It is unknown what patients expect from this treatment and whether these expectations are met. This study evaluates whether patients’ pre-treatment expectations of MRgRT are met and reports patients’ on-table experience on a 1.5 T MR-Linac.</p></div><div><h3>Materials and methods</h3><p>All patients treated on the MR-Linac from November 2020 until April 2021, were eligible for inclusion. Patient expectation and experience were captured through questionnaires before, during, and three months after treatment. The on-table experience questionnaire included patient’ physical and psychological coping. Patient-expected side effects, participation in daily and social activity, disease outcome and, disease related symptoms were compared to post-treatment experience.</p></div><div><h3>Results</h3><p>We included 113 patients who were primarily male (n = 100, 89 %), with a median age of 69 years (range 52–90). For on-table experience, ninety percent of patients (strongly) agreed to feeling calm during their treatment. Six and eight percent of patients found the treatment position or bed uncomfortable respectively. Twenty-eight percent of patients felt tingling sensations during treatment. After treatment, 79 % of patients’ expectations were met. Most patients experienced an (better than) expected level of side effects (75 %), participation in daily- (83 %) and social activity (86 %) and symptoms (78 %). However, 33 % expected more treatment efficacy than experienced.</p></div><div><h3>Conclusion</h3><p>Treatment on the 1.5 T MR-Linac is well tolerated and meets patient expectations. Despite the fact that some patients expected greater treatment efficacy and the frequent occurrence of tingling sensations during treatment, most patient experiences were comparable or better than previously expected.</p></div>","PeriodicalId":36328,"journal":{"name":"Technical Innovations and Patient Support in Radiation Oncology","volume":"29 ","pages":"Article 100224"},"PeriodicalIF":0.0,"publicationDate":"2023-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405632423000240/pdfft?md5=b9079f66d3a5754664a706af43d1b2c8&pid=1-s2.0-S2405632423000240-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138558647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and tolerability of breath-hold in liver stereotactic body radiotherapy with surface guided radiotherapy","authors":"Menekse Turna,&nbsp;Esra Küçükmorkoç,&nbsp;Rashad Rzazade,&nbsp;Mehmet Doğu Canoğlu,&nbsp;Nadir Küçük,&nbsp;Hale Basak Caglar","doi":"10.1016/j.tipsro.2023.100223","DOIUrl":"https://doi.org/10.1016/j.tipsro.2023.100223","url":null,"abstract":"<div><h3>Purpose</h3><p>Intrafractional motion constitutes a significant challenge in SBRT (Stereotactic Body Radiotherapy).The breath-hold (BH) technique is employed to mitigate tumor motion; however, ensuring reproducibility and consistency remains critically important. Surface tracking systems, integrated into the treatment process, facilitate motion tracking through three-dimensional camera technology. Surface guidance has been incorporated with Varian EDGE (Varian Medical Systems, Palo Alto, CA, USA) and has been utilized at multiple treatment sites within our department since 2018. Drawing on four years of experience, this study aims to publish patient experience, assess the feasibility, and evaluate the tolerability of breath-hold during SBRT with surface guided radiotherapy (SGRT), particularly focusing on a specific subgroup: patients with liver metastases.</p></div><div><h3>Methods</h3><p>Prospective evaluation was conducted on patients with liver metastases undergoing breath-hold SBRT with SGRT. A two-step survey consisting of seven questions was administered after CT simulation and treatment. Treatment duration and the number of breath-holds were recorded. Additionally, factors potentially influencing SGRT and treatment time were assessed.</p></div><div><h3>Results</h3><p>Between April 2021 and May 2022, a total of 41 patients underwent 171 fractions of treatment. According to the questionnaire, prior training was found to be beneficial, and breath-holding during the procedure was tolerable. Patients reported experiencing slight stress due to their active participation in the treatment. Factors such as Karnofsky Performance Status (KPS), age, lung volume, conditions affecting lung capacity, previous breath-hold history, and being a native speaker showed no correlation with treatment time. Moreover, these factors did not correlate with the tolerability of breath-hold during SGRT. However, female patients showed better breath-holding performance in SGRT treatments compared to male patients (p: 0.02).</p></div><div><h3>Conclusions</h3><p>The application of breath-hold with SGRT procedures is tolerable and feasible in liver SBRT treatments. There exists no specific subgroup that cannot tolerate this method.</p></div>","PeriodicalId":36328,"journal":{"name":"Technical Innovations and Patient Support in Radiation Oncology","volume":"28 ","pages":"Article 100223"},"PeriodicalIF":0.0,"publicationDate":"2023-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405632423000239/pdfft?md5=61baca190cdcef7749f12984661667f3&pid=1-s2.0-S2405632423000239-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138453823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal treatment with chemoradiotherapy, regional hyperthermia and interstitial brachytherapy for a huge locally advanced cervical cancer: A case report","authors":"Takashi Saito ,&nbsp;Motohiro Murakami ,&nbsp;Taisuke Sumiya ,&nbsp;Daisuke Kobayashi ,&nbsp;Haruka Shirataki ,&nbsp;Den Fujioka ,&nbsp;Keiichiro Baba ,&nbsp;Hiroya Itagaki ,&nbsp;Yuri Tenjimbayashi ,&nbsp;Toyomi Satoh ,&nbsp;Hideyuki Sakurai","doi":"10.1016/j.tipsro.2023.100222","DOIUrl":"https://doi.org/10.1016/j.tipsro.2023.100222","url":null,"abstract":"<div><p>A female patient in her 50 s was found to have a 10-cm tumor resulting from locally advanced cervical cancer (LACC). Three-year relapse-free survival was achieved following a multimodal treatment strategy integrating chemoradiotherapy (CRT), regional hyperthermia (RHT), and interstitial brachytherapy (ISBT). Given the large size of the tumor, enhancement of the geometrical dose distribution was anticipated using ISBT. However, delivery of a sufficient dose to the high-risk clinical target volume was predicted to be challenging. Thus, RHT was incorporated to potentially augment the overall treatment effect. This unique combination of CRT, RHT and ISBT may be promising for management of large LACC and warrants further investigation.</p></div>","PeriodicalId":36328,"journal":{"name":"Technical Innovations and Patient Support in Radiation Oncology","volume":"28 ","pages":"Article 100222"},"PeriodicalIF":0.0,"publicationDate":"2023-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2405632423000227/pdfft?md5=d5e62e8806cdab719d2f44f9cfc95490&pid=1-s2.0-S2405632423000227-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138395503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}