Medicon Medical Sciences最新文献

{"title":"Theoretical Functions of the Proton and Electron Pair to Mental Disorder with Biophysics","authors":"S. Sugihara, H. Maiwa","doi":"10.55162/mcms.03.073","DOIUrl":"https://doi.org/10.55162/mcms.03.073","url":null,"abstract":"We think the disease not only aging, or gets worse during the aging process like degenerative diseases. Alzheimer’s is a typical one, and there are many diseases not known the causes, or not clear. We must consider not only instrument like X-ray and CT scanning, but also causative agents and its mechanism with biophysics. Here we discuss schizophrenia, clinical depression, and Alzheimer’s. In the viewpoint, we focus on the receptor and neurotransmitter. We regard the amino acids are arginine, dopamine, serotonin, and Gaba as the neurotransmitter and the cause. Furthermore, we propose the treatment of the disease from chemical bonding strength of the substances. The method is to use the water which can reduce the state of neurotransmitter and receptor with the pair of proton and electron in the hydrogen bond dissociated water.","PeriodicalId":362642,"journal":{"name":"Medicon Medical Sciences","volume":"134 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121291700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Black Triangle Drugs (▼) - An Outline","authors":"AP Ravinandan, Nagarathna Poojary","doi":"10.55162/mcms.03.074","DOIUrl":"https://doi.org/10.55162/mcms.03.074","url":null,"abstract":"Each drugs undergoes clinical trial phase before introducing into pharmaceutical market. Generally clinical trials involve a small number of patients who take the medicine for a short period. During this phase, patients are carefully selected and followed up very closely under controlled conditions. These initial trials will report only more common adverse drug effects. But the rare and long latency adverse drug effects can be reported only when the medicine is consumed by a large population [1]. In a real-life setting, a larger and more diverse group of patients will take the medicines. They may have co-morbidities and they may be taking other concomitant medicines also. Some less common or rare side effects may only occur once a medicine has been used for a long time or duration by many people. It is therefore vital that the safety of all medicines continues to be monitored while they are in commercial use. Information is continuously collected after the medicine is placed on the market to monitor real-life experiences with the product. The Commission on Human Medicines (CHM) and Medicines and Healthcare products Regulatory Agency (MHRA) encourage the reporting of all suspected reactions to newly introduced medicines to the market.","PeriodicalId":362642,"journal":{"name":"Medicon Medical Sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117244569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Monkeypox Outbreak in India","authors":"","doi":"10.55162/mcms.03.068","DOIUrl":"https://doi.org/10.55162/mcms.03.068","url":null,"abstract":"","PeriodicalId":362642,"journal":{"name":"Medicon Medical Sciences","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127741830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive Factors of Mortality of Stroke in the Neurology Department of Hujr of Befelatanana in Antananarivo","authors":"F. Ravelosaona, Parany Haja Rabearisoa, Zafinirina Andriatoavina Rakoto, Séraphin, Espérant Andriamampilamina, Djacoba Alain Tehindrazanarivelo","doi":"10.55162/mcms.03.071","DOIUrl":"https://doi.org/10.55162/mcms.03.071","url":null,"abstract":"Introduction: Stroke is a major public health problem in the world. In Madagascar, mortality from strokes is still relevant. Eval-uating predictors of mortality would allow better treatment. Methods: This is a retrospective, descriptive and analytical study of the records of patients admitted to the neurology department during the period January 2015 to December 2019. There have been 1,565 cases of stroke. Results: The death rate from stroke ranges from 6% to 11%. Demographic characteristics are not predictors of mortality. Clinical features; especially the onset of complications are the predictors of death in stroke. Hemorrhagic stroke was a poor prognosis. Hospital stays of less than 10 days have been associated with mortality in patients with stroke. The NIHSS score has been a good prognostic tool for any type of stroke. For ischemic stroke, an ASPECTS score ≤ 7 was associated with mortality. For hemorrhagic stroke, the ICH score allows a good evaluation of the prognosis of these strokes. Conclusion: The establishment of a neurovascular unit in the University Hospital JR of Befelatanana would help better manage patients with stroke and other cerebrovascular diseases. National stroke surveys are needed to better identify national priori-ties.","PeriodicalId":362642,"journal":{"name":"Medicon Medical Sciences","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122721204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of Severe Acute Malnutrition in Children Aged 0-59 Months","authors":"T. Joséphine, Souam Nguele, Djidita Hagre, D. Granga, T. Abdelsalam, Brahim, O. Boy","doi":"10.55162/mcms.03.069","DOIUrl":"https://doi.org/10.55162/mcms.03.069","url":null,"abstract":"Introduction: Infant malnutrition is endemic in Chad. In 2018 in N’Djamena, the prevalence was 13.5%. This study aimed to identify factors influencing Severe Acute Malnutrition (SAM) in children under 59 months admitted to two Medical Feeding Centre in N’Djamena. Patients and method: We conducted a cross-sectional, descriptive and analytical study of the files of children aged 6 to 59 months admitted for severe acute malnutrition in two feeding centre in N’Djamena, from September 2019 to February 2020. The files were selected randomly, and the study sample size was calculated using the Schwarz formula. Descriptive and analytical analysis was done using Chi-2 and binary logistic regression; a P value < 0.05 is considered statistically significant. Results: Age 0-24 months (p = 0.001), breastfeeding mode (p = 0.027), early diarrhoea (p = 0.040), age of weaning (p = 0.013) and diversification (p = 0.034), self-medication (p = 0.047), and use of traditional care (p = 0.020) were significantly associated with SAM. The mother’s age and education level (p = 0.029) are also factors in the occurrence of SAM. Environmental hygiene and especially hand washing before feeding the child (p = 0.007) were significant for the occurrence of SAM. Conclusion: Factors related to the mother, the child and the environment interact closely to lead to SAM in the child. Only con crete and multidisciplinary actions can overcome this problem. served as the study framework. The study was a descriptive and analytical cross-sectional study conducted over six months which involved all children under 59 months admitted for severe acute malnutrition, with consenting mothers or caregivers. Children under 59 months admitted for Failure to Thrive associated with a chronic cardiovascular or cerebral pathology (cerebral palsy) and any malformation that could hinder their growth regardless of their diet were not included in the study. Sampling was random and concerned any case of severe acute malnutrition corresponding to the study population and the inclusion criteria. The sample size was 287 children. Variables studied: The dependent variable was the occurrence of severe acute malnutrition in children under 59 months-Independent variables: Socio-demographic characteristics of the child and the mother, socio-cultural characteristics, and environmental factors. Severe acute malnutrition is classified according to WHO 2006 standards [4]: Children aged 6 to 59 months whose W/H weight-height index is <-3 z-score and/or MUAC <115 mm and/or having nutritional oedemas. Pre-established questionnaires were sent to mothers and caregivers who consented. The available child follow-up notebooks were also consulted. We used the baby scale or SECA weight scale with 10 g precision; the Salter scale allows weighing up to 25kg with an accuracy of 0.100 kg. The electronic personal scale with an accuracy of 0.100 kg. The height was measured with the Shorr height chart for children; the Mid Upper Arm Cir-","PeriodicalId":362642,"journal":{"name":"Medicon Medical Sciences","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121282144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Covid Pandemic: Mental Health study in School Children and related Educational Myths","authors":"","doi":"10.55162/mcms.03.070","DOIUrl":"https://doi.org/10.55162/mcms.03.070","url":null,"abstract":"","PeriodicalId":362642,"journal":{"name":"Medicon Medical Sciences","volume":"594 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123045131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunity and Pancreatic Cancer","authors":"P. Sinha","doi":"10.55162/mcms.03.075","DOIUrl":"https://doi.org/10.55162/mcms.03.075","url":null,"abstract":"The pancreas has two morphologically and functionally distinct compartments: one comprising the exocrine cells, and the other comprising the endocrine cells [10]. The exocrine cells are the suppliers of various digestive enzymes to the upper small intestine through pancreatic duct, and the endocrine cells are the suppliers of various pancreatic hormones directly to the blood. Not surprisingly there are two broad divisions of Pancreatic Cancer (PC): the Exocrine Pancreatic Cancer, and the Neuroendocrine Pancreatic Cancer. The Exocrine Pancreatic Cancers are further divided into several sub-types that vary from each other histologically, and in symptoms and prognosis. Of these the Pancreatic Ductal Adenocarcinoma (PDAC), an Exocrine Pancreatic Cancer, is the most common amongst all the reported cases of PC. More than 90% of the PCs are found to be PDACs [12, 7]. From here on the term PC will be used to mean PDAC. PC is one of the deadliest cancers in the world because the PC is mostly detected when the tumor is not removable by surgery, and or the tumor has invaded the other organs of the body [9, 7, 3, 11]. There are three known precursor lesions of PC, without progressing through the various grades of which in steps PC does not develop [4, 2, 9]. These are Intraductal papillary mucinous neoplasms (IPMNs), mucinous","PeriodicalId":362642,"journal":{"name":"Medicon Medical Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133138974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence-Based Medicine in Orthopedic","authors":"J. Butarbutar","doi":"10.55162/mcms.03.061","DOIUrl":"https://doi.org/10.55162/mcms.03.061","url":null,"abstract":"interpret the results of RCT’s, systematic reviews, and meta-analyses and to combine them with their surgical experience before they decide how much of that new knowledge will change their daily practices.","PeriodicalId":362642,"journal":{"name":"Medicon Medical Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122846122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quadcare Model for Healthcare Providers","authors":"Preston L Williams, Joanna Williams, Bryce R. Williams","doi":"10.55162/mcms.03.062","DOIUrl":"https://doi.org/10.55162/mcms.03.062","url":null,"abstract":"Raising the discussion to participate in the evolution of a healthcare system that reflects the complexity and diversity of the modern integrated healthcare system in alignment with the community is well-documented. However, in this precarious hierarchical environment, there are necessary areas for improvement with respect to progressing the medical professional and key stakeholders beyond a paternalistic or traditional-minded practice. Integral to a synergy that will fuel the U.S. and global healthcare markets, this article aims to raise awareness for the audience through evidence-based materials about a paradigm shift in the operative definition of healthcare providers (ie clinical doctors) that has evolved to embrace four instrumental degrees within their respective fields of expertise, the MD, DO, DMSc (PA), and DNP (NP). Essential systematic changes serve to create parity amongst the aforementioned healthcare providers to maximize workplace diversification, inclusion, collaborative care, and professional satisfaction. All of which may translate to improved team dynamics, offset social determinants of health, and ultimately provide greater access to innovative and affordable quality care.","PeriodicalId":362642,"journal":{"name":"Medicon Medical Sciences","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126435981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ten Actions for Africa to be ready for the Next Pandemic","authors":"","doi":"10.55162/mcms.03.063","DOIUrl":"https://doi.org/10.55162/mcms.03.063","url":null,"abstract":"","PeriodicalId":362642,"journal":{"name":"Medicon Medical Sciences","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130431578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}