{"title":"A novel method for pulse transit time estimation using wrist bio-impedance sensing based on a regression model","authors":"Bassem Ibrahim, A. Akbari, R. Jafari","doi":"10.1109/BIOCAS.2017.8325054","DOIUrl":"https://doi.org/10.1109/BIOCAS.2017.8325054","url":null,"abstract":"Pulse transit time (PTT) is a promising method to estimate blood pressure using a wearable device. In this work, we explore the measurement of PTT using two bio-impedance (Bio-Z) sensors placed on the wrist 7.5 cm apart such that they can be integrated into a wrist watch. In order to take into account the different factors affecting blood flow in the wrist, a regression model is used based on multiple features extracted from the first and second derivative of Bio-Z. The estimated PTT is compared with a reference PTT measured from ECG and PPG sensors. Experimental measurements are conducted on three subjects and exhibited an average correlation coefficient of 0.77 for the PTT estimated from wrist Bio-Z compared to the reference PTT.","PeriodicalId":361477,"journal":{"name":"2017 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125668760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Takumi Katsuura, S. Izumi, M. Yoshimoto, H. Kawaguchi, S. Yoshimoto, T. Sekitani
{"title":"Wearable pulse wave velocity sensor using flexible piezoelectric film array","authors":"Takumi Katsuura, S. Izumi, M. Yoshimoto, H. Kawaguchi, S. Yoshimoto, T. Sekitani","doi":"10.1109/BIOCAS.2017.8325551","DOIUrl":"https://doi.org/10.1109/BIOCAS.2017.8325551","url":null,"abstract":"This report describes our proposed method of measuring pulse wave velocity (PWV) using a flexible piezoelectric film array. PWV is important cardiovascular information that can contribute to the early detection and treatment of hypertension and arteriosclerosis. Conventional methods used to calculate PWV measure the pulse transit time (PTT) between pulse waves measured at multiple positions of the body, or between an electrocardiogram (ECG) and a pulse wave. These methods require multiple devices to be worn on the body. By contrast, the proposed method realizes PTT measurement and PWV estimation using a single device incorporating a piezoelectric film array. Although it requires extraction of slight differences of pulse arrival times between pressure pulse waves with low signal-noise ratio (SNR), we introduce a signal processing method using cross correlation to resolve this difficulty. The proposed algorithm was applied to the pressure pulse wave measured using the prototype sensor at two points on the wrist. Measurements of four participants using the reference sensor confirmed that positive correlation was obtained with measured PTT. The correlation coefficient was as high as 0.94 with a low-noise condition.","PeriodicalId":361477,"journal":{"name":"2017 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115084005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Uluşan, S. Chamanian, Ö. Zorlu, A. Muhtaroğlu, H. Kulah
{"title":"Neural stimulation interface with ultra-low power signal conditioning circuit for fully-implantable cochlear implants","authors":"H. Uluşan, S. Chamanian, Ö. Zorlu, A. Muhtaroğlu, H. Kulah","doi":"10.1109/BIOCAS.2017.8325060","DOIUrl":"https://doi.org/10.1109/BIOCAS.2017.8325060","url":null,"abstract":"This paper presents an ultra-low power interface circuit to stimulate auditory nerves through fully-implantable cochlear implants (FICIs). The interface circuit senses signals generated from a multi-frequency piezoelectric sensor array, and generates neural stimulation current according to input sound level. Firstly, piezoelectric sensor output is amplified, and compressed with an ultra-low power logarithmic amplifier (LA). This significantly reduces power by eliminating the compression in the next stages. Then, amplified signal is envelope-detected, and utilized as a reference for stimulation current generation using a voltage controlled current source. Finally, biphasic stimulation current is delivered to the nerves through a switch matrix. The circuit has been designed and fabricated in 180nm high-voltage CMOS technology. 8-channel stimulator dissipates about 667 μW as it generates 110 μA biphasic stimulation current, while the front-end signal conditioning unit dissipates only 51.2 μW.","PeriodicalId":361477,"journal":{"name":"2017 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129724187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A low power architecture for AER event-processing microcontroller","authors":"S. Aiassa, P. Ros, G. Masera, M. Martina","doi":"10.1109/BIOCAS.2017.8325170","DOIUrl":"https://doi.org/10.1109/BIOCAS.2017.8325170","url":null,"abstract":"This paper presents a custom MSP430™-compatible microcontroller, specifically tailored for quasi-digital processing Address Event Representation (AER) events. Main target applications are fully reprogrammable sensory systems where events pre-processing has to be carried out by means of easily-tunable elaboration algorithms; a microcontroller-based design could provide the right trade-off between flexibility and performance. Key features are good time resolution, high reactivity, on-demand only processing and power consumption reduction. The proposed architecture has been analyzed and compared with an open source MSP430TM-compliant microcontroller (openMSP430) in terms of performance and power consumption. Accurate and wide cases-spectrum simulations (targeting ASIC technology) show an average power consumption reduction ranging from 50 % (same operating frequency) up to 79 % (same maximum event rate); equivalently, with the same power budget, an average improvement of either resolution of 84 % or maximum event rate of 1020 % is obtained.","PeriodicalId":361477,"journal":{"name":"2017 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"286 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124560528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Azhari, S. Yoshimoto, T. Nezu, Hirokazu Iida, Hiroki Ota, Yuki Noda, T. Araki, T. Uemura, T. Sekitani, Katsuyuki Morii
{"title":"A patch-type wireless forehead pulse oximeter for SpO2 measurement","authors":"A. Azhari, S. Yoshimoto, T. Nezu, Hirokazu Iida, Hiroki Ota, Yuki Noda, T. Araki, T. Uemura, T. Sekitani, Katsuyuki Morii","doi":"10.1109/BIOCAS.2017.8325557","DOIUrl":"https://doi.org/10.1109/BIOCAS.2017.8325557","url":null,"abstract":"A patch-type wireless wearable pulse oximeter system has been developed to measure the heart beat rate and oxygen saturation of blood (SpO2) in reflective mode from a person's forehead. The system uses light sources of two wavelengths (red, 625 nm; infrared, 865 nm) in an optical sensor, separates photodetector signal and transimpedance amplifier output into infrared (IR) and red photoplethysmographic (PPG) signals, and then digitizes and transmits data wirelessly via a Bluetooth module to a remote PC in real time, where the SpO2 value is calculated. The optical sensor, mounted on a 7 cm × 2 cm flexible sheet, is interfaced with an 8.5 cm × 3.5 cm wireless SpO2 circuit board. The entire sensor and wireless SpO2 system, which weighs only 15 g, is readily wearable on the forehead, unlike conventional non-wearable wired forehead pulse oximeters. Using our system, the reduction of SpO2 value was observed from 100% to 89%, under an 80 s breathhold condition, which matched with the simultaneously measured SpO2 values obtained using commercial pulse oximeters.","PeriodicalId":361477,"journal":{"name":"2017 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126848812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuhua Cheng, Dongdong Xuan, G. Qian, Guoxiong Chen, Maysam Ghovanloo, Gaofeng Wang
{"title":"Modeling of mm-sized solenoid coils with ferrite tube core for biomedical implants","authors":"Yuhua Cheng, Dongdong Xuan, G. Qian, Guoxiong Chen, Maysam Ghovanloo, Gaofeng Wang","doi":"10.1109/BIOCAS.2017.8325111","DOIUrl":"https://doi.org/10.1109/BIOCAS.2017.8325111","url":null,"abstract":"The sizes of the implanted biomedical devices are required to be millimeter in some applications, which poses a significant challenge for energizing the devices wirelessly. Inserting a ferrite tube into a solenoidal power receiving coil can keep the device compact, compared to the case of inserting a ferrite rod. In this paper, an analytical model of this solenoidal coil is established, based on an analytical effective permeability model of the ferrite tube. This new model is verified by simulation and can be used for designing the wireless power transfer system and optimizing the power transfer efficiency.","PeriodicalId":361477,"journal":{"name":"2017 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"194 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126995437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Myungjin Han, G. Ha, Eunji Cheong, G. Han, Youngcheol Chae
{"title":"An area/power efficient electrode-matched neural-spike detector embedded in implantable 256-channel MEA","authors":"Myungjin Han, G. Ha, Eunji Cheong, G. Han, Youngcheol Chae","doi":"10.1109/BIOCAS.2017.8325057","DOIUrl":"https://doi.org/10.1109/BIOCAS.2017.8325057","url":null,"abstract":"A compact area/power efficient electrode-matched neural-spike detector (NSD) is proposed to provide an implantable multi-electrode array (MEA). A correlation scheme with only the input sampling capacitors makes an area reduction, and the recording of neural-spike events enables a power reduction, showing 0.0044 mm2 and 0.55 μW. Together with proposed NSD, an implantable 256-channel MEA is fabricated. The electrical measurement results show that the NSD achieves an input-referred noise of 10.1 μVrms with 1 kHz to 10 kHz bandwidth, providing NEF/PEF/AEF of 1.71/5.28/0.0044, respectively, and CMRR of 67.5 dB. It shows ×7.5/×1.6 area/power improvements, compared to previous state-of-the-art NSDs. The fabricated implantable MEA is demonstrated by cell-cultured and brain-sliced experiments.","PeriodicalId":361477,"journal":{"name":"2017 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114233435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stability improvement and noise suppression in non-contact in-bed electrocardiogram measurement using laminated feedback electrode","authors":"Mayuko Takano, Hiromu Komiya, A. Ueno","doi":"10.1109/BIOCAS.2017.8325153","DOIUrl":"https://doi.org/10.1109/BIOCAS.2017.8325153","url":null,"abstract":"Herein, the effectiveness of a modified driven seat ground (mDSG) via additional feedback electrode (AFE) was evaluated in the non-contact capacitive electrocardiogram (ECG) measurement in terms of baseline restoration, common-mode noise suppression, and signal saturation recovery. Experiments with volunteers showed that the mDSG connected to the AFE and surrounded by ground considerably shortened the baseline restoration time to 2.9 s at minimum, reduced the common-mode noise by 90.5% at most with feedback gain of 1,000 V/V, and settled signal saturation shortly after the onset of the connection.","PeriodicalId":361477,"journal":{"name":"2017 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"141 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116277965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A photochemical dongle for point-of-care evaluation of blood lipid level","authors":"Xiwei Huang, Jinhong Guo","doi":"10.1109/BIOCAS.2017.8325049","DOIUrl":"https://doi.org/10.1109/BIOCAS.2017.8325049","url":null,"abstract":"Cardiovascular diseases are leading causes of death worldwide due to the building up of atherosclerotic plaques in the vasculature. As the formation of these plaques is closely related to the levels of cholesterol, effective measurement of cholesterol is critical for improving the diagnosis and management of cardiovascular diseases. With the wide use of smartphones all over the world in recent years, biomedical devices constructed with smartphones are capable of being widely applied in family-based smart health management. Thus, this paper proposes one smartphone-powered photochemical dongle for point-of-care (POC) monitoring of blood lipid (TC, TG, HDL-C) with a finger prick blood drop. By comparing the diagnostic results of 115 patients with the clinical biochemical analyzer, correlation coefficients larger than 0.903 have been obtained, which were highly acceptable and demonstrated the reliability and accuracy of the proposed photochemical dongle. The photochemical dongle thereby provides one promising solution for the future POC Cholesterol diagnostics.","PeriodicalId":361477,"journal":{"name":"2017 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128004717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. G. L. Kumar, R. S. Sairam, G. D. V. S. Kumar, S. Vanjari
{"title":"Low power, low area, analog blink restoration system with auto sleep mode for unilateral facial paralysis patients","authors":"M. G. L. Kumar, R. S. Sairam, G. D. V. S. Kumar, S. Vanjari","doi":"10.1109/BIOCAS.2017.8325064","DOIUrl":"https://doi.org/10.1109/BIOCAS.2017.8325064","url":null,"abstract":"Functional Electrical Stimulation is considered as one of the potential solutions for restoring the functionality of orbicularis oculi (a muscle that is responsible for eye-lid closure) in the patients suffering from Bells palsy. In this paper, we propose a synchronized blink function restoration system, wherein, the muscular activity of the healthy orbicularis oculi is sensed using EMG electrodes and a corresponding triggering pulse is provided to the non-functional muscle almost instantaneously. In this paper, we present the design of a low power blink restoration system comprising only low power analog blocks. The noise cancellation and filtration which typically is carried out in digital domain is replaced with a simple analog architecture. This resulted in a two fold reduction in power and more than hundred fold reduction in area. Furthermore, the designed system takes care of any false positives due to motion artifact. A simple mono-stable system based auto sleep mode is implemented to save power when the system is not in use. This analog blink restoration system designed in UMC 180nm CMOS technology has a Pre-amplifier gain of 20dB at 270Hz to 470Hz, CMRR > 70dB, input referred noise of less than 2 μVrms. It consumes power of 6 μW at 1.2V supply voltage and an area of 0.095 mm2.","PeriodicalId":361477,"journal":{"name":"2017 IEEE Biomedical Circuits and Systems Conference (BioCAS)","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128102805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}