Rossiiskii Oftal''mologicheskii Zhurnal最新文献

{"title":"Ultrasound diagnostic criteria of anterior ischemic optic neuropathy and optic neuritis","authors":"V. Neroev, T. N. Kiseleva, E. K. Eliseeva, A. Baeva, K. V. Lugovkina, M. V. Ryabina, V. E. Tankovsky","doi":"10.21516/2072-0076-2023-16-2-40-46","DOIUrl":"https://doi.org/10.21516/2072-0076-2023-16-2-40-46","url":null,"abstract":"Purpose: to determine objective echographic criteria for the differential diagnosis of anterior ischemic optic neuropathy (AION) and optic neuritis (ON).Material and methods. The research involved 60 patients aged 40 to 60 years, including 30 patients with suspected AION and 30 patients with suspected ON. The control group consisted of 40 healthy volunteers. In addition to the standard ophthalmological examination, all patients underwent ultrasound optic nerve s examination with measurement of the optic nerve thickness and acoustic density (AD) of the parenchyma and optic nerve sheets. Assessment of blood flow in retrobulbar vessels was carried out in the modes of Color Doppler Imaging and pulse dopplerography.Results. There were no statistically significant differences in average echographic parameters of the optic nerve s thickness between the groups of patients with AION and ON. In patients with ON there was a statistically significant decrease in the average AD index compared to that in patients with AION and in healthy volunteers (106.02 ± 5.40 y. e., 146.58 ± 9.70 y.e. and 135.3 ± 2.1 y. e., accordingly). The AD values in all patients with AION exceeded 133 y. e., in patients with ON this index was less than 132 y. e. Evaluation of hemodynamic parameters in the vessels of the eye demonstrated a statistically significant decrease in the peak systolic velocity (Vsyst) and end-diastolic velocity (Vdiast) blood flow in the central retinal artery and medial and lateral short posterior ciliary arteries in patients with AION (in 2-fold) compared with ON and normal indices (p < 0.001). There were no statistically significant differences between parameters of blood flow in patients with ON and in healthy volunteers. In addition, there were no significant intergroup differences of hemodynamic parameters of the ophthalmic artery (p > 0.05).Conclusions. AD of the optic nerve and parameters of blood flow velocities (Vsyst and Vdiast) in medial and lateral short posterior ciliary arteries can be attributed to the diagnostic criteria of the AION and ON.","PeriodicalId":36080,"journal":{"name":"Rossiiskii Oftal''mologicheskii Zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49366779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of α2-macroglobulin in endogenous uveitis in children","authors":"L. Katargina, N. Chesnokova, E. Denisova, M. A. Khrabrova, O. Beznos","doi":"10.21516/2072-0076-2023-16-2-16-21","DOIUrl":"https://doi.org/10.21516/2072-0076-2023-16-2-16-21","url":null,"abstract":"Purpose: to analyze the activity of α2-macroglobulin (α2-MG) in the tear, blood serum (BS), and aqueous humour (AH) in children with uveitis, and to assess the possibility of using α2-MG for inflammation activity estimation and prognosis.Material and methods. 76 children with uveitis (135 eyes) aged 3 to 17 (ave. 10.45 ± 3.34 years), were tested for the activity of α2-MG (300 tear samples, 154 BS samples, 39 AH samples). The dynamics of α2-MG was assessed in the tear of 56 patients, and in BS of 53 patients. α2-MG activity was determined by the enzymatic method using the specific substrate N-benzoyl-DL-arginine-p-nitroanilide (BAPNA). The optical density was measured using a multifunctional photometer for Synergy MX microplates (BioTek, USA).Results. No correlation was found between the α2-MG activity and the inflammation activity and localization of uveitis. In contrast, a significant decrease in α2-MG activity was found in the tear after anti-inflammatory therapy (p = 0.013). Also, a significant preoperative α2-MG increase was noted in the tear of children who experienced fibrin effusion into the anterior chamber of the eye in the early postoperative period (p = 0.022) It was shown that α2-MG activity in BS drops significantly as the patients grow up (p = 0.025). As the degree of proliferation increases, the activity of α2-MG in AH also increases (p = 0.049).Conclusion. An increase of α2-MG activity in the tears in the preoperative period may be important for the prognosis of fibrin formation in the anterior chamber during the postoperative period. α2-MG in the tear is highly sensitive to anti-inflammatory drugs, which reduce its activity. In BS the highest activity of α2-MG was revealed at the age of 3–6 years, whereupon it is decreasing. In AH, the activity of α2-MG correlates with the stage of the proliferative process.","PeriodicalId":36080,"journal":{"name":"Rossiiskii Oftal''mologicheskii Zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48773406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using artificial neural networks for early diagnosis of glaucoma","authors":"E. N. Komarovskikh, E. V. Podtynnykh","doi":"10.21516/2072-0076-2023-16-2-28-32","DOIUrl":"https://doi.org/10.21516/2072-0076-2023-16-2-28-32","url":null,"abstract":"Purpose: to summarize the experience of the development and application of artificial neural networks (ANW) in early diagnosis of primary open-angle glaucoma (POAG).Material and methods. A total of 690 patients (918 eyes) were tested. The training clinical group consisted of 459 clinical examples (459 eyes), of which 369 eyes had an initial stage of POAG and 90 eyes had no glaucoma. The testing clinical group was represented by 131 examples (131 eyes), of which 110 eyes belonged to patients with POAG and 21 eyes were without glaucoma. The final diagnostic testing using ANW was conducted on 328 eyes with the diagnosis unknown to the researchers, which belonged to people with suspected POAG. The diagnostic complex included an optimally necessary set of research techniques.Results. ANW identified glaucoma in 198 eyes out of those with suspected glaucoma (60.4 %) with 100 % certainty. 76 eyes (23.2 %) were classified as non-glaucoma, or “healthy”; 54 eyes of the suspected glaucoma patients were identified as “doubtful”, whereupon they were retested by a neural network pool consisting of 5 neural networks. According to the results of the retesting, 28 eyes, or 51.9 % of the “doubtful” ones were identified as having glaucoma, whereas 26 eyes (48.1 %) were identified as non-glaucomatous, i. e. healthy.Conclusion. Our experience suggests that artificial neural networks pose no danger to the doctor or the patient and can be viewed as a very convenient tool for early POAG diagnostics.","PeriodicalId":36080,"journal":{"name":"Rossiiskii Oftal''mologicheskii Zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45514555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The systemic angiotensin-II role in the development of retinopathy of prematurity","authors":"N. A. Osipova, N. Chesnokova, L. Katargina, T. Pavlenko, O. Beznos, A. Panova","doi":"10.21516/2072-0076-2023-16-2-63-66","DOIUrl":"https://doi.org/10.21516/2072-0076-2023-16-2-63-66","url":null,"abstract":"Purpose: to determine the role of the systemic angiotensin II (AT-II) in the pathogenesis of retinopathy of prematurity (ROP) and assess its prognostic value.Material and methods. 34 premature infants at risk of developing ROP were examined according to the ophthalmological ROP screening protocol adopted in the Russian Federation. Retrospectively, the infants were divided into 2 groups: those without ROP (n = 15) and those with developed ROP (n = 19). The average gestational age of those without ROP was 28.12 ± 0.64 weeks, their average body weight at birth was 1164 ± 118.6 g. The respective values for the group with ROP were 27.8 ± 0.6 weeks and 1142.6 ± 108.4 g. The two groups had similar extent of general somatic burden. At 32–35 weeks and 36–39 weeks of post-conceptual age (PCA), the infants of both groups were tested for the concentration of AT-II in blood serum using the enzyme-linked immunosorbent assay (ELISA).Results: on the 32–35 week of PCA, the average level of AT-II in blood serum of premature infants of the ROP group was significantly increased as compared to that of the non-ROP group (p = 0.03), while on the 36–39 week of PCA no statistically significant difference between the AT-II levels in the examined groups was found (p = 0.73).Conclusion. We established that the systemic AT-II level has a trigger role in the development of ROP. A high level of this parameter found at the onset of ROP can be considered as an early prognostic criterion for the risk of ROP development.","PeriodicalId":36080,"journal":{"name":"Rossiiskii Oftal''mologicheskii Zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46683031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficiency of surgical treatment of neovascular glaucoma: a retrospective analysis","authors":"A. Zolotarev, E. Karlova, M. V. Radaikina, A. A. Kuz'mina, O. Ryzhkova","doi":"10.21516/2072-0076-2023-16-2-12-15","DOIUrl":"https://doi.org/10.21516/2072-0076-2023-16-2-12-15","url":null,"abstract":"Purpose: to compare the results of neovascular glaucoma (NVG) surgery of patients treated for the underlying eye disease with antiVEGF therapy and laser coagulation (LC) of the retina with the surgery results of patients who did not receive underlying disease treatment.Materials and methods. A retrospective analysis of case histories and outpatient charts of 70 patients (70 eyes) with NVG, operated in a surgical hospital, involved two groups of patients: group 1 — 33 eyes of patients treated for the underlying disease with anti-VEGF therapy and/or LC; of these, 13 eyes (39 %) received panretinal LC, 15 eyes (45 %) received an anti-VEGF drug intravitreally, and 5 eyes (16 %) received both anti-VEGF therapy and LC); group 2 — 37 eyes of patients not treated for the underlying disease. In group 1, NVG was caused by diabetic retinopathy (DR), which accounted for 19 eyes (57.6 %), and post-thrombotic retinopathy (PR) — 14 eyes (42.3 %). IOP data in group 1 at admission was 38.00 ± 6.82 mm Hg. In group 2, the proportion of patients with DR was 32 % (12 eyes), and those with PR — 41 % (15 eyes). The level of IOP in group 1 upon hospital admission was 38.00 ± 6.82 mm Hg, while in group 2 it was 35.97 ± 5.85 mm Hg.Results. In group 1, in most cases, the classical surgical approach to NVG treatment was used. The proportion of Ahmed drainage implantations was 46 % (15 eyes), trabeculectomy (TET) — 24 % (8 eyes), non-penetrating sinustrabeculectomy (NST) — 6 % (2 eyes), and only 24 % (8 eyes) received transscleral cyclophotocoagulation (CPC). After 7 days, the average level of IOP in group 1 was 16.80 ± 7.18 mm Hg, after 1 month, 19.50 ± 3.45 mm Hg, after 3 months, 21.80 ± 3.15 mm Hg, and after 6 months — 22.57 ± 3.34 mm Hg (p < 0.05). In group 2, the operation of choice was CFC, which was performed in 46 % (17 eyes), the Ahmed drainage was implanted less often — 36 % (13 eyes), while 18 % (7 eyes) accounted for TET. The IOP level in group 2 after 7 days was 20.00 ± 8.74 mm Hg, after 1 month, 25.30 ± 4.67 mm Hg, after 3 months 28.43 ± 6.54 mm Hg, and after 6 months 29.73 ± 4.18 mm Hg (p < 0.05).Conclusion. The timely treatment of the underlying disease with Anti-VEGF and LC of the retina allows the patient to maintain visual functions, and increases the effectiveness of NVG surgery.","PeriodicalId":36080,"journal":{"name":"Rossiiskii Oftal''mologicheskii Zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45841938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of myopia among teenager students of Orenburg city schools","authors":"A. Aprelev, S. V. Cherkasov, P. E. Serebryakova, A. A. Aprelev, P. S. Cherkasova","doi":"10.21516/2072-0076-2023-16-2-7-11","DOIUrl":"https://doi.org/10.21516/2072-0076-2023-16-2-7-11","url":null,"abstract":"Purpose: to study the prevalence and manifestation features of myopia in students of educational schools in the city of Orenburg.Material and methods. 710 schoolchildren of Orenburg schools, aged 11 to 18, were examined.Results. Myopia was found to be the most common pathology of the eye, diagnosed in 33.5 % of schoolchildren. The most frequent was low myopia claiming 65.4 % of myopic cases, followed by moderate myopia (28.5 %) and high myopia (6.1 %). The highest occurrence of myopia was revealed in 11th and 8th grade students (respectively, 55.8 and 40,0 cases per 100 examined subjects). It was found out that the share of more severe myopia stages (moderate and high) in increasing in older age groups 5th-grade to 11th-grade students. We also showed that myopia prevalence is connected with head and spine injuries in the case history.Conclusion. Educational facilities need to introduce an effective system of myopia prevention and means of progression reduction.","PeriodicalId":36080,"journal":{"name":"Rossiiskii Oftal''mologicheskii Zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45129974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On classification approaches, terminology and modern principles of treatment of pathologies associated with high myopia. Part 3. Approaches to monitoring and treatment of patients","authors":"V. Neroev, O. V. Zaytseva, E. Tarutta, E. V. Bobykin, M. Kovalevskaya, R. Fayzrakhmanov, P. A. Nechiporenko","doi":"10.21516/2072-0076-2023-16-1-supplement-23-39","DOIUrl":"https://doi.org/10.21516/2072-0076-2023-16-1-supplement-23-39","url":null,"abstract":"High myopia is a common ametropia associated with a significant risk of multiple comorbidities. Decreased visual functions of myopic patients may be caused by non-specific diseases such as cataracts, glaucoma and rhegmatogenous retinal detachment, which are very likely in myopia. Yet especially important are the specific changes such as atrophic, traction and neovascular manifestations of pathological myopia, the totality of which is defined as myopic macular degeneration or myopic maculopathy. The review highlights current approaches to the diagnosis and treatment of various diseases associated with high myopia, including original schemes for managing patients with myopic choroidal neovascularization and myopic traction maculopathy, developed by experts from the Expert Council on Retinal and Optic Nerve Diseases of the Russian nationwide public body Association of ophthalmologists, and includes an information leaflet for patients.","PeriodicalId":36080,"journal":{"name":"Rossiiskii Oftal''mologicheskii Zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49377505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On classification approaches, terminology and modern principles of treatment of pathologies associated with high myopia. Part 1. Criteria for high myopia and pathological myopia","authors":"V. Neroev, O. V. Zaytseva, E. Tarutta, E. V. Bobykin, M. Kovalevskaya, R. Fayzrakhmanov, P. A. Nechiporenko","doi":"10.21516/2072-0076-2023-16-1-supplement-7-14","DOIUrl":"https://doi.org/10.21516/2072-0076-2023-16-1-supplement-7-14","url":null,"abstract":"Myopic refraction is the most common ocular pathology, currently affecting about 1.5 billion people worldwide. Recent decades have seen a trend towards a significant increase in myopia prevalence, which is likely to continue in the near future. Therefore, we observe some kind of an epidemic of myopia. The greatest concern is caused by cases of uncorrectable visual impairment associated with myopia, which make pathological (degenerative) myopia one of the leading causes of low vision and blindness in many countries. At the same time, there is still no uniform interpretation of such important concepts as “high myopia” and “pathological myopia”, which can negatively affect various aspects of clinical and scientific interaction among ophthalmologists. The article provides an overview of modern work on the above issues and proposes definitions of terms to be used in the healthcare system of the Russian Federation","PeriodicalId":36080,"journal":{"name":"Rossiiskii Oftal''mologicheskii Zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43456719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On classification approaches, terminology and modern principles of treatment of pathologies associated with high myopia. Part 2. Terminology and approaches to classification","authors":"V. Neroev, O. V. Zaytseva, E. Tarutta, E. V. Bobykin, M. Kovalevskaya, R. Fayzrakhmanov, P. A. Nechiporenko","doi":"10.21516/2072-0076-2023-16-1-supplement-15-22","DOIUrl":"https://doi.org/10.21516/2072-0076-2023-16-1-supplement-15-22","url":null,"abstract":"Axial myopia is a risk factor for the development of many concomitant pathological conditions, including those likely to lead to an irreversible loss of visual functions. Until now, specialists disagree about the terminology and the approaches to classification of pathological myopia. We propose a critical analysis of the state-of-the-art research and use them to offer, the definitions of such conditions as “myopic macular degeneration (myopic maculopathy)”, “myopic choroidal neovascularization” and “myopic traction maculopathy” and recommend them for use in the healthcare system of the Russian Federation","PeriodicalId":36080,"journal":{"name":"Rossiiskii Oftal''mologicheskii Zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43726770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traditional analogue vs. three-dimensional digital visualization used in ophthalmic surgery","authors":"V. S. Stebnev, A. V. Zhuravlev","doi":"10.21516/2072-0076-2023-16-1-168-174","DOIUrl":"https://doi.org/10.21516/2072-0076-2023-16-1-168-174","url":null,"abstract":"The visualization of the surgical process remains a topical issue in cataract surgery. The review presents the history of visualization technique in ophthalmic surgery and compares the main current analogue and 3D digital technologies. The advent of 3D imaging systems in clinical practice has helped solve many issues associated with the use of standard analogue microscopes. These issues include limited focus and field of vision, the need to use a large amount of light, which increases the risk of iatrogenic retinal phototoxicity, the surgeon's attachment to the microscope and, consequently, a high load on the surgeon's visual apparatus when using eyepieces, as well as on their back and neck muscles.","PeriodicalId":36080,"journal":{"name":"Rossiiskii Oftal''mologicheskii Zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48367474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}