Engineered Science最新文献

Effect of Mineralizers on the Preparation and Chromatic Properties of Cerium/Praseodymium Co-doped Yellow Ceramic Pigments 矿化剂对铈镨共掺黄色陶瓷颜料制备及着色性能的影响

Engineered Science Pub Date : 2025-01-01 DOI: 10.30919/es1880

Feng Jiang, J.-M. Liu, Junxiong Zhang, Zhibin Chen, Guo Feng, Quan Zhang, Xiaojun Zhang, Jianmin Liu

引用次数: 0

High-performance and Energy-saving Tire Tread Rubber Achieved Through Synergistic Charge Regulation and Flexible Bridging Interface 通过协同电荷调节和柔性桥接界面实现高性能节能轮胎胎面橡胶

Engineered Science Pub Date : 2025-01-01 DOI: 10.30919/es1760

Shuaishuai Cheng, Bingang Xu, Xiaoyuan Duan, Yaqing Liu

引用次数: 1

Investigation of Uridine in Anti-Aging-Related Diseases Based on Network Pharmacology, Molecular Docking and Cell Experimental Validation 基于网络药理学、分子对接和细胞实验验证的尿苷抗衰老相关疾病研究

Engineered Science Pub Date : 2025-01-01 DOI: 10.30919/es1572

Hongxia Ma, Xiaowei Dai, Tao Wang, Zhongmei He, Rui Du, Hongyan Pei, Tianyuan Liu, Ruifen Sun, Kui Zhao

{"title":"Investigation of Uridine in Anti-Aging-Related Diseases Based on Network Pharmacology, Molecular Docking and Cell Experimental Validation","authors":"Hongxia Ma, Xiaowei Dai, Tao Wang, Zhongmei He, Rui Du, Hongyan Pei, Tianyuan Liu, Ruifen Sun, Kui Zhao","doi":"10.30919/es1572","DOIUrl":"https://doi.org/10.30919/es1572","url":null,"abstract":"There is currently only literature that verifies through in vivo experiments in animals that uridine can increase the metabolic level in mice, lacking research and validation on the anti-aging mechanism of uridine.Using network pharmacology, 83 drug targets and 5758 disease targets were screened out, and 33 common targets between aging-related diseases and the selected uridine were determined, including key proteins (PLA2G2A, ADK, G6PD, and GLA).Ten core targets were screened out from the PPI network (TP53, INS, CASP3, MYC, ADA, SERPINE1, SLC2A4, DPP4, G6PD, and TYMS).Molecular docking provided further verification.The CCK-8 experiment demonstrated that uridine has a significant therapeutic effect on D-galactose-induced senescence in HT22, BV2, and PC12 cells.Biochemical index detection results indicated that uridine can reduce the content of MDA and the enzyme activity of LDH in senescent HT22, BV2, and PC12 cells, increase the enzyme activity of SOD, and lower the expression levels of inflammatory factors IL-1 and TNF-, thereby reducing the damage to HT22, BV2, and PC12 cells caused by inflammatory factors.This study highlights the potential of uridine as a source of anti-aging activity and suggests that it can be developed into a new drug for treating aging-related diseases.","PeriodicalId":36059,"journal":{"name":"Engineered Science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.espublisher.com/uploads/article_pdf/es1572_JustAccepted.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147877630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Enhancing Prostate Cancer Subtyping: A Persistent Homology Approach in Multiple Instance Learning 增强前列腺癌亚型：多实例学习中的持续同源性方法

Engineered Science Pub Date : 2025-01-01 DOI: 10.30919/es1905

Ahmad Obeid, Sajid Javed, Jorge Dias, Ibrahim Abe M. Elfadel, Naoufel Werghi

引用次数: 0

Autonomous Enrichment of Ultra-low Concentration Sb(III) by Gradient P(AA-AM-NH2-β-CD) Hydrogels Reinforced via Hofmeister Effect 经Hofmeister效应强化的梯度P（AA-AM-NH2-β-CD）水凝胶自主富集超低浓度Sb(III

Engineered Science Pub Date : 2025-01-01 DOI: 10.30919/es1644

Zihan Han, Yuhan Zhang, Qianyuan Wang, Wenhui Zhang, Kunyan Sui, Pengfei Qi

引用次数: 2

Construction of 0D Zinc Oxide Nanoparticles Anchored on the Surface of 2D MXene Functional Materials for High-efficiency Photocatalytic Removal of Organic Pollutants: Roles of Nanoconfinement Effect and Interface Effect 二维MXene功能材料表面0D氧化锌纳米颗粒的构建及其在高效光催化去除有机污染物中的作用：纳米约束效应和界面效应

Engineered Science Pub Date : 2025-01-01 DOI: 10.30919/es1655

Chuanxi Yang, Mingfan Zhang, WU Yong-kun, Kaipeng Sun, Haowei Dang, Yadong Xu, Jinran Zhang, Chen Zhang, Ruihong Chang, Erling Zhao, Yunlong Lan, Haofen Sun, Dong Chen, Weihua Zhao, Yihua Xiao, Yizhen Tang, Yuqi Fan, Weiliang Wang, Feng Dang, Xiaoning Wang

{"title":"Construction of 0D Zinc Oxide Nanoparticles Anchored on the Surface of 2D MXene Functional Materials for High-efficiency Photocatalytic Removal of Organic Pollutants: Roles of Nanoconfinement Effect and Interface Effect","authors":"Chuanxi Yang, Mingfan Zhang, WU Yong-kun, Kaipeng Sun, Haowei Dang, Yadong Xu, Jinran Zhang, Chen Zhang, Ruihong Chang, Erling Zhao, Yunlong Lan, Haofen Sun, Dong Chen, Weihua Zhao, Yihua Xiao, Yizhen Tang, Yuqi Fan, Weiliang Wang, Feng Dang, Xiaoning Wang","doi":"10.30919/es1655","DOIUrl":"https://doi.org/10.30919/es1655","url":null,"abstract":"Among the available semiconductors, TiO2 plays a significant role in charge transport mechanism for the third-generation solar devices.The presence of trap states decreases the overall charge injection efficiency of the device.This can be improved by mixing a small amount of Fe2O3 with the TiO2 nanoparticles.This leads to expedite the injection of electrons from the semiconductor conduction band to the FTO conduction band, thereby reducing the charge recombination.Here, we have deposited three types of films, i.e., single, double and triple layer of TiO2 with mixing of Fe2O3 in it.These films were characterized for solar device fabrication.The sample prepared with 2 wt.% with two layers coating, significantly improves the device performance.Sustaining a high fill factor requires controlling the flaws by surface passivation.The Fe2O3 can be considered as a good candidate for enhanced DSSC's applications.","PeriodicalId":36059,"journal":{"name":"Engineered Science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.espublisher.com/uploads/article_pdf/cs1655.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147894562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Omni-Surface Hydrophobic Bamboo Composite with Enhanced Antibacterial and Self-Cleaning Performance 增强抗菌和自清洁性能的全表面疏水竹复合材料

Engineered Science Pub Date : 2025-01-01 DOI: 10.30919/es1593

Zixuan Wang, Yanni Tan, Chun Shi, Hanhui Lei, Xiaoteng Liu, Mohamed Kallel, Zhengjun Shi

引用次数: 3

Highly Efficient Florfenicol Removal via Nitrogen-Doped Zero-Valent Iron/Carbon Composites Activated with Peroxodisulfate: Mechanisms and Pathways 过硫酸盐活化氮掺杂零价铁/碳复合材料高效去除氟苯尼考：机制和途径

Engineered Science Pub Date : 2025-01-01 DOI: 10.30919/es1535

Peng Yu, Shun Wang, Xin Chen, Zhiguo Wang, Chun Zhang, Yanxue Shang, Wei Huang

{"title":"Highly Efficient Florfenicol Removal via Nitrogen-Doped Zero-Valent Iron/Carbon Composites Activated with Peroxodisulfate: Mechanisms and Pathways","authors":"Peng Yu, Shun Wang, Xin Chen, Zhiguo Wang, Chun Zhang, Yanxue Shang, Wei Huang","doi":"10.30919/es1535","DOIUrl":"https://doi.org/10.30919/es1535","url":null,"abstract":"Florfenicol (FF) accumulation in aquatic environments is a critical concern due to ecosystem disruption, microbial resistance, and health risks.While zero-valent iron (ZVI) is recognized for antibiotic remediation, studies on FF removal using nitrogendoped ZVI-based materials activated by peroxodisulfate (PDS) and their degradation mechanisms are limited.This study synthesizes N-doped ZVI/C-1 via pyrolysis of ironbased metal-organic frameworks (MOFs), where organic ligands form a carbon matrix supporting ZVI particles and incorporate nitrogen atoms.The resulting N-doped ZVI/C-1 exhibits increased defect density, higher specific surface area, and improved hydrophobicity compared to ZVI/C.Electrochemical analyses further reveal that Ndoped ZVI/C-1 possesses superior corrosion resistance, faster charge transport, and reduced hydrogen evolution activity.Consequently, N-doped ZVI/C-1 achieves a high FF removal efficiency of 96.0% within 30 minutes when activated by PDS.Mechanistic investigations indicate that the dominant degradation involves the generation of OH and SO4 radicals, resulting in higher dechlorination and defluorination capacities compared to ZVI/C.Identified degradation pathways include C-Cl and C-F bond cleavage, C=O addition, and benzene ring decomposition, leading to a gradual reduction in FF toxicity.This study presents a promising strategy for FF removal and enhances the understanding of degradation mechanisms utilizing nitrogen-doped ZVIbased materials.","PeriodicalId":36059,"journal":{"name":"Engineered Science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.espublisher.com/uploads/article_pdf/es1535_JustAccepted.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147918891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Engineered Sustainable Substitute: Roots of Seed-propagated Saposhnikovia divaricata at Bolting-stage as a Crop Engineering Solution for Wild Resource Replacement 工程可持续替代品：种子繁殖的三叶草抽苔期根作为野生资源替代的作物工程解决方案

Engineered Science Pub Date : 2025-01-01 DOI: 10.30919/es1663

Qingqing Zhang, Li‐Zhu Wu, Xiaolu Chen, Yubo Hu, Miaomiao Tao, Jing Wang, Chunying Ma

引用次数: 0

Analyzing Climate Change Perception and Adaptation Methods of People in the North-Western Himalayas, Kashmir 喀什米尔喜玛拉雅山西北部地区人们对气候变化的感知与适应方法分析

Engineered Science Pub Date : 2025-01-01 DOI: 10.30919/es1489

Mohmad Abass Bhat, Pratima Gajbhiye, Irfan Khursheed Shah, Rouoof Habib Ganie, Miral R. Thakker, Saurav Dixit, Nikolai Vatin, Ghanshyam G. Tejani, Chandrakant Sonawane

{"title":"Analyzing Climate Change Perception and Adaptation Methods of People in the North-Western Himalayas, Kashmir","authors":"Mohmad Abass Bhat, Pratima Gajbhiye, Irfan Khursheed Shah, Rouoof Habib Ganie, Miral R. Thakker, Saurav Dixit, Nikolai Vatin, Ghanshyam G. Tejani, Chandrakant Sonawane","doi":"10.30919/es1489","DOIUrl":"https://doi.org/10.30919/es1489","url":null,"abstract":"This study examines how indigenous people in Bandipora, Jammu and Kashmir, India, perceive climate change and their adaptive strategies to cope with environmental changes.It also investigates their beliefs about the implications of climate change.The study employed purposive sampling to select the area and random sampling to choose 400 household respondents from Quailmuqam, Malangam, and Panar areas.Data was collected using semi-structured interviews and focus group discussions.The findings indicate that 82.6% of respondents observed rising temperatures, 91.8% noted a decline in snowfall frequency, 89.3% reported reduced snowfall intensity, 89.5% saw a decrease in rainfall frequency, and 90.8% experienced lower rainfall intensity.Additionally, respondents reported deteriorating forest and pasture lands, shrinking snow cover, and diminished water availability.Most respondents believe extreme weather events are becoming more frequent and will continue to do so, with 80% anticipating increased glacial outbursts, landslides, and floods, potentially harming their livelihoods.To address these challenges, respondents have adopted measures such as social forestry, water conservation, fire control, intercropping, crop rotation, and soil conservation techniques like mulching and terracing.This study provides valuable insights into indigenous perceptions and adaptive practices, aiding policymakers in developing more effective climate resilience strategies for the Himalayan region.","PeriodicalId":36059,"journal":{"name":"Engineered Science","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.espublisher.com/uploads/article_pdf/es1489_JustAccepted.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147911962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1