Journal of Mycology and Infection最新文献_第6页

A Case of Stenotrophomonas maltophilia SkinInfection at a Flap Site 皮瓣部位嗜麦芽窄养单胞菌皮肤感染1例

Journal of Mycology and Infection Pub Date : 2021-06-30 DOI: 10.17966/jmi.2021.26.2.48

S. Oh, J. H. Park, S. Park, J. Kim, Hyun-Min Seo

引用次数: 0

An Investigation of Clinical and Mycological Characteristicsof Onychomycosis in Fishing Villages 渔村甲真菌病的临床和病原学特征调查

Journal of Mycology and Infection Pub Date : 2021-06-30 DOI: 10.17966/jmi.2021.26.2.28

W. Jin, Gyeong Je Cho, S. Hong, Jong Uk Kim, J. Seol, S. Park, J. Choi, Ki-Hong Kim, Hyojin Kim

{"title":"An Investigation of Clinical and Mycological Characteristics\u0000of Onychomycosis in Fishing Villages","authors":"W. Jin, Gyeong Je Cho, S. Hong, Jong Uk Kim, J. Seol, S. Park, J. Choi, Ki-Hong Kim, Hyojin Kim","doi":"10.17966/jmi.2021.26.2.28","DOIUrl":"https://doi.org/10.17966/jmi.2021.26.2.28","url":null,"abstract":"Background: Many studies have investigated onychomycosis in various populations. However, no study has been conducted among individuals living in fishing villages, who seem to be more susceptible to onychomycosis.\u0000Objective: This study was conducted to investigate the prevalence, clinical and mycological characteristics, and risk factors of onychomycosis in individuals living in fishing villages located on two small islands.\u0000Methods: Individuals who had resided in fishing villages located on two small islands in Korea were included. Inspection and a questionnaire survey were performed, and clinical assessment and mycological identification using polymerase chain reaction were performed for those diagnosed with onychomycosis on inspection.\u0000Results: Among the 43 subjects enrolled, 32 (74.4%) were clinically diagnosed with onychomycosis. Causative organisms were identified in 23 (53.5%) subjects, and the most common identified causative strain was Trichophyton rubrum (91.3%), followed by Trichophyton species (4.3%) and Candida species (4.3%). Distal and lateral subungual onychomycosis was the most common clinical type (78.1%), followed by total dystrophic\u0000onychomycosis (12.5%). In 10 subjects (31.3%), five or more nails were affected. Among the patients who received treatment for onychomycosis (n = 19), 66.7% had used only conventional topical agents.\u0000Conclusion: Onychomycosis is more prevalent and more severe in people living in fishing villages than in the general population. These findings suggest that environmental or occupational background should be considered in managing onychomycosis.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41319606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

COVID-19-associated Pulmonary Aspergillosis:A New Entity covid -19相关肺曲霉病:一个新的实体

Journal of Mycology and Infection Pub Date : 2021-06-30 DOI: 10.17966/jmi.2021.26.2.23

Hyun-Min Seo, Ji Hun Park, S. Oh, S. Park, J. Kim

引用次数: 0

Evaluation of the Efficacy and Safety of Efinaconazole10% Topical Solution for the Treatment of ToenailOnychomycosis: A Multicenter, Single-arm,Open-label Phase 4 Study 10%依非那唑局部溶液治疗甲真菌病的疗效和安全性评价：一项多中心、单臂、开放标签的4期研究

Journal of Mycology and Infection Pub Date : 2021-06-30 DOI: 10.17966/jmi.2021.26.2.35

Jin Hee Kim, J. H. Lee, J. Park, H. Ko, J. Choi, Hyojin Kim, Jee-Bum Lee, Jin Park, B. Kim, Yangwon Lee

{"title":"Evaluation of the Efficacy and Safety of Efinaconazole\u000010% Topical Solution for the Treatment of Toenail\u0000Onychomycosis: A Multicenter, Single-arm,\u0000Open-label Phase 4 Study","authors":"Jin Hee Kim, J. H. Lee, J. Park, H. Ko, J. Choi, Hyojin Kim, Jee-Bum Lee, Jin Park, B. Kim, Yangwon Lee","doi":"10.17966/jmi.2021.26.2.35","DOIUrl":"https://doi.org/10.17966/jmi.2021.26.2.35","url":null,"abstract":"Background: Onychomycosis is a common nail fungal infection that affects the nail bed, plate, and matrix. It accounts for ~50% of all nail diseases. The treatment of onychomycosis includes systemic and topical approaches, which depend on patient compliance, drug penetration and delivery to the nail bed, antifungal efficacy, and\u0000tolerance. Efinaconazole is a novel triazole antifungal agent that is active against many pathogenic fungi, and is used for treating onychomycosis.\u0000Objective: To confirm the efficacy and safety of 10% efinaconazole solution for treating onychomycosis.\u0000Methods: This study was conducted as a 52-week, multicenter, open, single-group, phase 4 clinical trial. A 10% efinaconazole solution was applied on the toenails of each subject before bedtime, once a day for 48 weeks. The subjects visited the test facility every four weeks for the evaluation of the efficacy and safety of the treatment.\u0000Results: At 52 weeks of applying 10% efinaconazole solution, the rates of complete cure, mycological cure, complete or almost complete cure, and clinical effectiveness were 16.7%, 95.8%, 38.54%, and 52.1%, respectively. The clinical effects of efinaconazole were seen in more than half of the subjects. No severe adverse reactions related to efinaconazole were observed.\u0000Conclusion: The antifungal effect and safety of topically applied 10% efinaconazole solution in patients with mild to moderate toenail onychomycosis caused by dermatophytes was confirmed based on the efficacy and safety evaluation for a complete cure.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48663697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First Report of Chromoblastomycosis caused byFonsecaea nubica in South Korea 韩国首例由牛毛方引起的色母细胞真菌病报告

Journal of Mycology and Infection Pub Date : 2021-06-30 DOI: 10.17966/jmi.2021.26.2.45

K. Park, Eun Hye Lee, S. Lee, Y. Bang, J. Jun, J. Choi, Dae-Lyong Ha, J. Kim, Y. Jang, Seok-Jong Lee, W. Lee

引用次数: 0

Tinea Faciei Caused by Trichophyton verrucosumMisdiagnosed as Contact Dermatitis 疣状毛癣引起的面癣误诊为接触性皮炎

Journal of Mycology and Infection Pub Date : 2020-12-31 DOI: 10.17966/JMI.2020.25.4.76

Dong Won Lee, Sangbin Jeong, M. Suh, G. Ha, Jong Im Lee, J. Choi

引用次数: 0

Onychomycosis as a Chronic Superficial Fungal Infection:"Why is it so Hard to Clear?" 甲真菌病是一种慢性浅表真菌感染:为什么它很难清除?

Journal of Mycology and Infection Pub Date : 2020-12-31 DOI: 10.17966/JMI.2020.25.4.65

Ji-In Seo, M. Shin

{"title":"Onychomycosis as a Chronic Superficial Fungal Infection:\u0000\"Why is it so Hard to Clear?\"","authors":"Ji-In Seo, M. Shin","doi":"10.17966/JMI.2020.25.4.65","DOIUrl":"https://doi.org/10.17966/JMI.2020.25.4.65","url":null,"abstract":"Onychomycosis is a fungal infection of the nail unit. Compared to other superficial dermatophytoses of the skin and hair, onychomycosis is associated with a chronic course and frequent recurrence. Originally, structural characteristics of the nail, such as poor vascular supply and thick layers of hard keratin, were thought to be limiting\u0000factors for efficient drug delivery, resulting in prolonged treatment. However, recent research reveals the following crucial mechanisms contributing to the chronicity of nail dermatophytosis: innate characteristics of Trichophyton rubrum, formation of dormant spores called arthroconidia, physical and immunologic characteristics of the nail\u0000apparatus, and alteration of the defense system of the host. T. rubrum, the most common causative fungal pathogen for onychomycosis, acquires selective immune tolerance toward the host's defense system. Transformation into dormant phases, such as arthroconidia, creates greater resistance to antifungal medication and nonnutritive\u0000environments. The anatomical and biological structures of the nail allow immune evasion, increase infection susceptibility, and promote biofilm formation. Key regulators of the host's innate and adaptive immune systems are downregulated as infection persists, and age-associated immunomodulation aggravates the process.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44807069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pneumonia with Empyema Caused by Cladosporium veloxin a Patient with Rheumatoid Arthritis 类风湿关节炎并发梭菌致肺炎并发脓胸a例

Journal of Mycology and Infection Pub Date : 2020-12-31 DOI: 10.17966/JMI.2020.25.4.71

Yu-Mi Lee, S. Cho, K. Park, M. S. Lee, Young Jin Kim

引用次数: 0

Primary Cutaneous Sporotrichoid Nocardiosis Caused byNocardia brasiliensis 由巴西诺卡菌引起的原发性皮肤孢子体诺卡菌病

Journal of Mycology and Infection Pub Date : 2020-12-31 DOI: 10.17966/JMI.2020.25.4.79

Dong Won Lee, Sangbin Jeong, M. Suh, G. Ha, Jong Im Lee

引用次数: 0

COVID-19 and Fungal Infection 新冠肺炎与真菌感染

Journal of Mycology and Infection Pub Date : 2020-09-30 DOI: 10.17966/jmi.2020.25.3.47

J. Lee, Hwan Yook

引用次数: 0