Journal of Mycology and Infection最新文献

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Differentiating Verruca Plana and Palmoplantar Keratoderma by Comparing Clinical Features 通过比较临床特征区分掌跖疣和掌跖角化病
Journal of Mycology and Infection Pub Date : 2023-09-30 DOI: 10.17966/jmi.2023.28.3.68
Hui Young Shin, Woo Kyoung Choi, Yu Jeong Park, Ai-Young Lee, S. Lee, Jong Soo Hong
{"title":"Differentiating Verruca Plana and Palmoplantar Keratoderma by Comparing Clinical Features","authors":"Hui Young Shin, Woo Kyoung Choi, Yu Jeong Park, Ai-Young Lee, S. Lee, Jong Soo Hong","doi":"10.17966/jmi.2023.28.3.68","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.3.68","url":null,"abstract":"Background: Distinguishing verruca plana (VP) from certain types of palmoplantar keratoderma (PPK) can pose challenges as there are few prior investigations. Objective: This study aimed to enhance the differentiation between VP and PPK by analyzing their clinical characteristics. Methods: We conducted a retrospective study involving patients diagnosed with VP, or PPK based on biopsy results. Results: We identified 38 cases with VP/PPK-like lesions on their hands. Among them, ten (26.3%) were diagnosed with VP, while 15 (39.5%) were diagnosed with PPK. VP lesions predominantly manifested on the dorsum of the hand, whereas PPK was primarily observed on the palm, and dorsum. Erythematous, or brownish-colored lesions were more commonly associated with VP, while PPK lesions typically presented as flesh-colored. Conclusion: By comparing the clinical distinctions between VP, and PPK, we aim to provide valuable insights to facilitate the differentiation of these two conditions, which can sometimes be diagnostically challenging.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139332027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Disseminated Coccidioidomycosis Confirmed by Skin Biopsy in Korea 韩国一例通过皮肤活检确认的播散性球孢子菌病病例
Journal of Mycology and Infection Pub Date : 2023-09-30 DOI: 10.17966/jmi.2023.28.3.74
Yi Na Yoon, Ji Won Lim, Hyung Seok Son, Y. Cho, Yang Won Lee, Y. Choe, Dang Yu
{"title":"A Case of Disseminated Coccidioidomycosis Confirmed by Skin Biopsy in Korea","authors":"Yi Na Yoon, Ji Won Lim, Hyung Seok Son, Y. Cho, Yang Won Lee, Y. Choe, Dang Yu","doi":"10.17966/jmi.2023.28.3.74","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.3.74","url":null,"abstract":"Disseminated coccidioidomycosis is an uncommon fungal infection primarily observed in immunocompromised individuals. Infection typically occurs when individuals inhale fungal spores in endemic areas such as the southwestern United States and parts of Central and South America. However, globalization has increased the number of reported cases outside endemic areas. Herein, we present an unusual case of coccidioidal meningitis, a rare but fatal complication of disseminated coccidioidomycosis, in an immunocompetent patient who previously resided in an endemic area.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139332630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overview of Malassezia Infection and Candidiasis 马拉色菌感染和念珠菌病概述
Journal of Mycology and Infection Pub Date : 2023-09-30 DOI: 10.17966/jmi.2023.28.3.61
Jisoo Kim, Joonsoo Park
{"title":"Overview of Malassezia Infection and Candidiasis","authors":"Jisoo Kim, Joonsoo Park","doi":"10.17966/jmi.2023.28.3.61","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.3.61","url":null,"abstract":"Malassezia infection and candidiasis are commonly encountered in dermatology clinics and need to be differentiated from other fungal infections or skin diseases. These can be diagnosed by a simple test, such as the KOH procedure, and can be appropriately treated to relieve patient discomfort. In this article, we reviewed the diseases caused by Malassezia (i.e., pityriasis versicolor and Malassezia folliculitis) and various superficial skin infections caused by Candida.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139333163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Green Nail Syndrome caused by Enterococcus durans and Enterococcus hirae 由杜兰肠球菌和平滑肠球菌引起的绿甲综合征病例
Journal of Mycology and Infection Pub Date : 2023-09-30 DOI: 10.17966/jmi.2023.28.3.90
Jueon Roh, Jisoo Kim, Jisung Kim, Taekwoon Kim, Joonsoo Park
{"title":"A Case of Green Nail Syndrome caused by Enterococcus durans and Enterococcus hirae","authors":"Jueon Roh, Jisoo Kim, Jisung Kim, Taekwoon Kim, Joonsoo Park","doi":"10.17966/jmi.2023.28.3.90","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.3.90","url":null,"abstract":"","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139333874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic Use of Posaconazole for Cutaneous Purpureocillium lilacinum Infection Refractory to Itraconazole 泊沙康唑治疗伊曲康唑难治的皮肤紫癜疫霉菌感染
Journal of Mycology and Infection Pub Date : 2023-09-30 DOI: 10.17966/jmi.2023.28.3.79
Jin Ho Kim, Y. Bang, Jae Bok Jun, Weon Ju Lee
{"title":"Therapeutic Use of Posaconazole for Cutaneous Purpureocillium lilacinum Infection Refractory to Itraconazole","authors":"Jin Ho Kim, Y. Bang, Jae Bok Jun, Weon Ju Lee","doi":"10.17966/jmi.2023.28.3.79","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.3.79","url":null,"abstract":"Purpureocillium lilacinum is a saprophytic fungus with a ubiquitous environmental distribution. Unfortunately, no standard treatment has yet been established for cutaneous P. lilacinum infections. Based on the in vitro antifungal susceptibility test, posaconazole has been considered an effective treatment option. We herein present a case involving a 72-year-old woman who visited our clinic due to a peripherally spreading, well-demarcated, asymptomatic, scaly, and erythematous patch on her forehead that had persisted for 4 months. She had been diagnosed with cutaneous P. lilacinum infection and had been treated with itraconazole (200 mg/day). However, the lesion recurred in the same area. Histopathological findings revealed suppurative granulomatous dermatitis with fungal elements. Fungal culture confirmed P. lilacinum regrowth. Posaconazole was selected to treat the recurrence of P. lilacinum infection. After 10 weeks of treatment, the lesion decreased dramatically without any adverse drug events. We recommend posaconazole as a treatment option for P. lilacinum infection refractory to itraconazole.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139331910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subcutaneous Basidiobolomycosis: A Rare and Underdiagnosed but Curable Fungal Infection - A Case Report 皮下巴西双孢子菌病:罕见、诊断不足但可治愈的真菌感染--病例报告
Journal of Mycology and Infection Pub Date : 2023-09-30 DOI: 10.17966/jmi.2023.28.3.84
Yoana Fransiska Wahyuning Christi, Irmadita Citrashanty, Yuri Widia, Sylvia Anggraeni, L. Astari, Daniel Edbert, A. P. Kawilarang, Evy Ervianti
{"title":"Subcutaneous Basidiobolomycosis: A Rare and Underdiagnosed but Curable Fungal Infection - A Case Report","authors":"Yoana Fransiska Wahyuning Christi, Irmadita Citrashanty, Yuri Widia, Sylvia Anggraeni, L. Astari, Daniel Edbert, A. P. Kawilarang, Evy Ervianti","doi":"10.17966/jmi.2023.28.3.84","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.3.84","url":null,"abstract":"Basidiobolomycosis is a rare deep fungal infection caused by Basidiobolus ranarum and characterized by the development of swollen erythematous nodular lesions. Several azoles have been shown to be an effective treatment for this condition. Herein, we report a case of basidiobolomycosis that was initially misdiagnosed as a different disease and resolved after itraconazole medication. A 25-year-old man presented with a 2.5-year history of extensive swelling on his right arm, face, and neck. Initially, he was diagnosed with lipoma and scapular tuberculosis; however, no improvements were observed post-surgery and with tuberculosis medication. Histopathological examinations revealed giant cells, aseptate hyphae, and the Splendore-Hoeppli phenomenon. Fungal culture confirmed the isolate to be Basidiobolus ranarum. The patient was given oral itraconazole 200 mg twice daily, and the complete resolution was achieved after 25 months of treatment.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139332554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Red Ginseng Water Extract Aggravates Inflammation inSebocytes and Outer Root Sheath Cells after Treatment withLipopolysaccharide and Mice with Cutibacterium acnesinducedInflammatory Nodules 红参水提取物在脂多糖处理后加重皮脂细胞和外根鞘细胞的炎症以及小鼠痤疮杆菌诱导的炎症结节
Journal of Mycology and Infection Pub Date : 2023-06-30 DOI: 10.17966/jmi.2023.28.2.42
M. Kwack, Seung Soo Lee, Weon Ju Lee
{"title":"Red Ginseng Water Extract Aggravates Inflammation in\u0000Sebocytes and Outer Root Sheath Cells after Treatment with\u0000Lipopolysaccharide and Mice with Cutibacterium acnesinduced\u0000Inflammatory Nodules","authors":"M. Kwack, Seung Soo Lee, Weon Ju Lee","doi":"10.17966/jmi.2023.28.2.42","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.2.42","url":null,"abstract":"Background: Ginseng, a well-known health-supportive herbal medicine in Korea, has various forms, including red ginseng (RG) produced through steaming and drying white ginseng. RG has been associated with numerous protective functions in various diseases.\u0000Objective: The objective of this study was to investigate whether RG water extract exacerbates inflammation in human sebocytes and outer root sheath (ORS) cells following treatment with lipopolysaccharide (LPS) and Cutibacterium acnes strain (ATCC 1182)-induced inflammatory nodules in mice.\u0000Methods: Sebocytes and ORS cells were isolated and cultured from the human scalp. Reverse transcriptionpolymerase chain reaction and enzyme-linked immunosorbent assay were used to measure the expression of inflammatory cytokine and sebum-related genes after treatment with RG and LPS. Mice with Cutibacterium acnesinduced\u0000inflammatory nodules were orally administered RG in water for two weeks, and immunofluorescence staining was performed to assess the inflammatory nodules.\u0000Results: RG enhanced LPS-mediated inflammation by increasing the mRNA and protein expression of interleukin (IL)-1β, IL-6, IL-8, and tumor necrosis factor-α in sebocytes and ORS cells. RG also upregulated the expression of p-nuclear factor-kappa B (p-NFκB), p-c-Jun, and c-Jun N-terminal kinase (p-JNK) in LPS-treated sebocytes and ORS cells. Moreover, RG promoted LPS-induced sebum production in sebocytes. Additionally, RG hindered the improvement of inflammatory nodules in mice and increased the expression of inflammatory biomarkers, such as neutrophil, myeloperoxidase, and IL-1β, as well as tissue remodeling biomarkers, such as myeloperoxidase (MMP)-2, MMP-3, and MMP-9 in the inflammatory nodules.\u0000Conclusion: Our findings strongly suggest that RG exacerbates acne vulgaris. It is advisable to avoid using RG in patients with inflammatory acne.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48888426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dermoscopic and Scanning Electron Microscopic Finding ofEctothrix Tinea Capitis by Microsporum canis 犬小孢子虫引起头癣外溢的皮肤镜及扫描电镜观察
Journal of Mycology and Infection Pub Date : 2023-06-30 DOI: 10.17966/jmi.2023.28.2.58
Sang-Kyung Lee, Geon-Jong Lee, Kyung-Hwa Nam, Jin Park
{"title":"Dermoscopic and Scanning Electron Microscopic Finding of\u0000Ectothrix Tinea Capitis by Microsporum canis","authors":"Sang-Kyung Lee, Geon-Jong Lee, Kyung-Hwa Nam, Jin Park","doi":"10.17966/jmi.2023.28.2.58","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.2.58","url":null,"abstract":"revealed multiple round erythematous scaly patches with broken hair in the hairless area. Dermoscopic examination showed Morse code-like and sharp-angled zigzag hair with transverse white bands across the hair shaft (Fig. 1A). Scanning electron microscopy of the affected hair revealed thin and destroyed cuticles covered with numerous fungal arthro-conidia corresponding to the white bands on the hair shaft (Fig. 1B-1E). Microsporum canis was identified as the causative species via fungal culture and polymerase chain reaction. The patient received a treatment of oral griseofulvin (125 mg/day) and topical terbinafine for 8 weeks. Dermatophyte infections of the hair can result in three distinct patterns of fungal invasion: ectothrix, endothrix, or favus, depending on the specific species involved 1 . Ectothrix tinea capitis, often associated with Microsporum canis, is characterized by the accumulation of arthroconidia around the exterior of the hair shaft, leading to the circumferential destruction of the hair cuticle 2 . As the infected hair continues to grow, the affected portion rises above the scalp surface and becomes more prone to bending or breaking due to increased fragility. This gives rise to the appearance of Morse code-like or bent zigzag hair with transverse white bands, indicating focal weakening of the hair shaft caused by fungal invasion 3 . Understanding this information can assist clinicians in predicting the type of fungal invasion and comprehending the formation mechanism behind the distinctive dermoscopic features observed in cases of ectothrix tinea capitis.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45063867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Candidal Granuloma on the Lip Masquerading asSquamous Cell Carcinoma 唇部假丝酵母菌肉芽肿伪装成鳞状细胞癌
Journal of Mycology and Infection Pub Date : 2023-06-30 DOI: 10.17966/jmi.2023.28.2.54
J. Kim, Y. Jang, Seok-Jong Lee
{"title":"Candidal Granuloma on the Lip Masquerading as\u0000Squamous Cell Carcinoma","authors":"J. Kim, Y. Jang, Seok-Jong Lee","doi":"10.17966/jmi.2023.28.2.54","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.2.54","url":null,"abstract":"Skin fungal infections are sometimes misdiagnosed as malignancies and vice versa. Herein, we present the case of a 78-year-old woman who visited our clinic because of a rapidly growing \"hard-crusted nodule\" on the lower lip persisting for 1 month. Keratoacanthoma or squamous cell carcinoma (SCC) was initially considered. However,\u0000the histopathological findings revealed suppurative granuloma and fungal elements without atypical cells. Candida albicans was grown in tissue culture. The lesions were treated with topical ketoconazole. After 2 years, the patient revisited because of a black-crusted nodule on the left corner of her mouth that had been persisting for 1 month. The nodule resembled SCC. Histopathological examination revealed suppurative granuloma and fungal elements. After confirming Candida glabrata in fungal culture, the lesion was diagnosed as candidal granuloma and disappeared spontaneously without any treatment. Herein, we report a case of candidal granuloma on lip mimicking recurrent malignancies.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42391532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiological and Demographic Study of Patientswith Mucormycosis and COVID-19 毛霉菌病与COVID-19的流行病学和人口学研究
Journal of Mycology and Infection Pub Date : 2023-06-30 DOI: 10.17966/jmi.2023.28.2.35
N. Saki, Alireza Rafati Navaei, Ali Delirrooyfard, M. Jahangiri, Roomina Bagheri
{"title":"Epidemiological and Demographic Study of Patients\u0000with Mucormycosis and COVID-19","authors":"N. Saki, Alireza Rafati Navaei, Ali Delirrooyfard, M. Jahangiri, Roomina Bagheri","doi":"10.17966/jmi.2023.28.2.35","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.2.35","url":null,"abstract":"Background: Coronavirus disease 2019 (COVID-19) is associated with many bacterial and fungal diseases. Aspergillus and Candida have been reported as major pathogens resulting to comorbid infections in COVID-19 patients.\u0000Objective: Recent studies have shown a considerable burden of cases affected by mucormycosis after coronavirus disease 2019 (COVID-19) infection worldwide, and some underlying factors may contribute to this condition. Hence, this study aimed to investigate the epidemiology and demographic characteristics of mucormycosis patients after COVID-19 infection in the Ahvaz province of Iran.\u0000Methods: This descriptive-analytical epidemiological study was conducted on patients who developed mucormycosis following COVID-19 for a 6-month period in 2021. A checklist based on symptoms and possible risk factors was used to collect patient information.\u0000Results: The results showed that conjunctivitis, ophthalmalgia, facial swelling, feeling of pain or pressure in the face, and sinusitis were the most common clinical manifestations of patients with mucormycosis following COVID-19. Additionally, there was a significant association between corticosteroid and prophylactic antibiotic use, pain or pressure in the face, and ophthalmalgia with the outcome variables including alive or dead (p-values = 0.002, 0.011, 0.034, and 0.004, respectively). No statistically significant difference was found between the ages of the two groups (p-value = 0.495).\u0000Conclusion: The study findings revealed that the most common risk factors for mortality include diabetes, immune system defects, and use of prophylactic antibiotics or corticosteroids.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48316575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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