Hui Young Shin, Woo Kyoung Choi, Yu Jeong Park, Ai-Young Lee, S. Lee, Jong Soo Hong
{"title":"Differentiating Verruca Plana and Palmoplantar Keratoderma by Comparing Clinical Features","authors":"Hui Young Shin, Woo Kyoung Choi, Yu Jeong Park, Ai-Young Lee, S. Lee, Jong Soo Hong","doi":"10.17966/jmi.2023.28.3.68","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.3.68","url":null,"abstract":"Background: Distinguishing verruca plana (VP) from certain types of palmoplantar keratoderma (PPK) can pose challenges as there are few prior investigations. Objective: This study aimed to enhance the differentiation between VP and PPK by analyzing their clinical characteristics. Methods: We conducted a retrospective study involving patients diagnosed with VP, or PPK based on biopsy results. Results: We identified 38 cases with VP/PPK-like lesions on their hands. Among them, ten (26.3%) were diagnosed with VP, while 15 (39.5%) were diagnosed with PPK. VP lesions predominantly manifested on the dorsum of the hand, whereas PPK was primarily observed on the palm, and dorsum. Erythematous, or brownish-colored lesions were more commonly associated with VP, while PPK lesions typically presented as flesh-colored. Conclusion: By comparing the clinical distinctions between VP, and PPK, we aim to provide valuable insights to facilitate the differentiation of these two conditions, which can sometimes be diagnostically challenging.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139332027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yi Na Yoon, Ji Won Lim, Hyung Seok Son, Y. Cho, Yang Won Lee, Y. Choe, Dang Yu
{"title":"A Case of Disseminated Coccidioidomycosis Confirmed by Skin Biopsy in Korea","authors":"Yi Na Yoon, Ji Won Lim, Hyung Seok Son, Y. Cho, Yang Won Lee, Y. Choe, Dang Yu","doi":"10.17966/jmi.2023.28.3.74","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.3.74","url":null,"abstract":"Disseminated coccidioidomycosis is an uncommon fungal infection primarily observed in immunocompromised individuals. Infection typically occurs when individuals inhale fungal spores in endemic areas such as the southwestern United States and parts of Central and South America. However, globalization has increased the number of reported cases outside endemic areas. Herein, we present an unusual case of coccidioidal meningitis, a rare but fatal complication of disseminated coccidioidomycosis, in an immunocompetent patient who previously resided in an endemic area.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139332630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Overview of Malassezia Infection and Candidiasis","authors":"Jisoo Kim, Joonsoo Park","doi":"10.17966/jmi.2023.28.3.61","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.3.61","url":null,"abstract":"Malassezia infection and candidiasis are commonly encountered in dermatology clinics and need to be differentiated from other fungal infections or skin diseases. These can be diagnosed by a simple test, such as the KOH procedure, and can be appropriately treated to relieve patient discomfort. In this article, we reviewed the diseases caused by Malassezia (i.e., pityriasis versicolor and Malassezia folliculitis) and various superficial skin infections caused by Candida.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":"901 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139333163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jueon Roh, Jisoo Kim, Jisung Kim, Taekwoon Kim, Joonsoo Park
{"title":"A Case of Green Nail Syndrome caused by Enterococcus durans and Enterococcus hirae","authors":"Jueon Roh, Jisoo Kim, Jisung Kim, Taekwoon Kim, Joonsoo Park","doi":"10.17966/jmi.2023.28.3.90","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.3.90","url":null,"abstract":"","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139333874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Therapeutic Use of Posaconazole for Cutaneous Purpureocillium lilacinum Infection Refractory to Itraconazole","authors":"Jin Ho Kim, Y. Bang, Jae Bok Jun, Weon Ju Lee","doi":"10.17966/jmi.2023.28.3.79","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.3.79","url":null,"abstract":"Purpureocillium lilacinum is a saprophytic fungus with a ubiquitous environmental distribution. Unfortunately, no standard treatment has yet been established for cutaneous P. lilacinum infections. Based on the in vitro antifungal susceptibility test, posaconazole has been considered an effective treatment option. We herein present a case involving a 72-year-old woman who visited our clinic due to a peripherally spreading, well-demarcated, asymptomatic, scaly, and erythematous patch on her forehead that had persisted for 4 months. She had been diagnosed with cutaneous P. lilacinum infection and had been treated with itraconazole (200 mg/day). However, the lesion recurred in the same area. Histopathological findings revealed suppurative granulomatous dermatitis with fungal elements. Fungal culture confirmed P. lilacinum regrowth. Posaconazole was selected to treat the recurrence of P. lilacinum infection. After 10 weeks of treatment, the lesion decreased dramatically without any adverse drug events. We recommend posaconazole as a treatment option for P. lilacinum infection refractory to itraconazole.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139331910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yoana Fransiska Wahyuning Christi, Irmadita Citrashanty, Yuri Widia, Sylvia Anggraeni, L. Astari, Daniel Edbert, A. P. Kawilarang, Evy Ervianti
{"title":"Subcutaneous Basidiobolomycosis: A Rare and Underdiagnosed but Curable Fungal Infection - A Case Report","authors":"Yoana Fransiska Wahyuning Christi, Irmadita Citrashanty, Yuri Widia, Sylvia Anggraeni, L. Astari, Daniel Edbert, A. P. Kawilarang, Evy Ervianti","doi":"10.17966/jmi.2023.28.3.84","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.3.84","url":null,"abstract":"Basidiobolomycosis is a rare deep fungal infection caused by Basidiobolus ranarum and characterized by the development of swollen erythematous nodular lesions. Several azoles have been shown to be an effective treatment for this condition. Herein, we report a case of basidiobolomycosis that was initially misdiagnosed as a different disease and resolved after itraconazole medication. A 25-year-old man presented with a 2.5-year history of extensive swelling on his right arm, face, and neck. Initially, he was diagnosed with lipoma and scapular tuberculosis; however, no improvements were observed post-surgery and with tuberculosis medication. Histopathological examinations revealed giant cells, aseptate hyphae, and the Splendore-Hoeppli phenomenon. Fungal culture confirmed the isolate to be Basidiobolus ranarum. The patient was given oral itraconazole 200 mg twice daily, and the complete resolution was achieved after 25 months of treatment.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139332554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Red Ginseng Water Extract Aggravates Inflammation in\u0000Sebocytes and Outer Root Sheath Cells after Treatment with\u0000Lipopolysaccharide and Mice with Cutibacterium acnesinduced\u0000Inflammatory Nodules","authors":"M. Kwack, Seung Soo Lee, Weon Ju Lee","doi":"10.17966/jmi.2023.28.2.42","DOIUrl":"https://doi.org/10.17966/jmi.2023.28.2.42","url":null,"abstract":"Background: Ginseng, a well-known health-supportive herbal medicine in Korea, has various forms, including red ginseng (RG) produced through steaming and drying white ginseng. RG has been associated with numerous protective functions in various diseases.\u0000Objective: The objective of this study was to investigate whether RG water extract exacerbates inflammation in human sebocytes and outer root sheath (ORS) cells following treatment with lipopolysaccharide (LPS) and Cutibacterium acnes strain (ATCC 1182)-induced inflammatory nodules in mice.\u0000Methods: Sebocytes and ORS cells were isolated and cultured from the human scalp. Reverse transcriptionpolymerase chain reaction and enzyme-linked immunosorbent assay were used to measure the expression of inflammatory cytokine and sebum-related genes after treatment with RG and LPS. Mice with Cutibacterium acnesinduced\u0000inflammatory nodules were orally administered RG in water for two weeks, and immunofluorescence staining was performed to assess the inflammatory nodules.\u0000Results: RG enhanced LPS-mediated inflammation by increasing the mRNA and protein expression of interleukin (IL)-1β, IL-6, IL-8, and tumor necrosis factor-α in sebocytes and ORS cells. RG also upregulated the expression of p-nuclear factor-kappa B (p-NFκB), p-c-Jun, and c-Jun N-terminal kinase (p-JNK) in LPS-treated sebocytes and ORS cells. Moreover, RG promoted LPS-induced sebum production in sebocytes. Additionally, RG hindered the improvement of inflammatory nodules in mice and increased the expression of inflammatory biomarkers, such as neutrophil, myeloperoxidase, and IL-1β, as well as tissue remodeling biomarkers, such as myeloperoxidase (MMP)-2, MMP-3, and MMP-9 in the inflammatory nodules.\u0000Conclusion: Our findings strongly suggest that RG exacerbates acne vulgaris. It is advisable to avoid using RG in patients with inflammatory acne.","PeriodicalId":36021,"journal":{"name":"Journal of Mycology and Infection","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48888426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}