Usharani Nimmagadda, M Ramez Salem, Dimitry Voronov, Nebojsa Nick Knezevic
{"title":"The NuMask® is as Effective as the Face Mask in Achieving Maximal Preoxygentation.","authors":"Usharani Nimmagadda, M Ramez Salem, Dimitry Voronov, Nebojsa Nick Knezevic","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Background: Preoxygenation before anesthetic induction is a widely accepted maneuver to\u0000increase oxygen reserves and delay desaturation during apnea. There is limited data regarding the\u0000use of the NuMask® in the perioperative setting, and no data as to its efficacy in achieving maximal\u0000preoxygenation. We hypothesize that the NuMask® may be a useful alternative to the face mask in\u0000achieving maximal preoxygenation.\u0000Methods: After IRB approval, the NuMask® was compared with the classic face mask\u0000with respect to achieving maximal pre-oxygenation in 30 healthy volunteers using tidal volume\u0000breathing. All volunteers were tested for three periods of 5 minutes intervals and the following\u0000parameters were recorded every 30 seconds: inspired, and end-tidal oxygen concentration and endtidal\u0000carbon dioxide concentration.\u0000Results: The mean ETO2 of ≥90% was achieved with both masks at 3.5 minutes (SD =\u00001.62 and 1.98 for facemask and NuMask® respectively) and thereafter the ETO2 remained above\u000090%. There were no statistical differences noted in FiO2 and ETO2 between the face mask and the\u0000NuMask® in the same time periods. ETCO2 values were also not statistically different between the\u0000two masks.\u0000Conclusions: The study showed that the NuMask® is as effective as the classic face mask in\u0000achieving maximal pre-oxygenation during tidal volume breathing.\u0000Introduction</p>","PeriodicalId":35975,"journal":{"name":"Middle East Journal of Anesthesiology","volume":"23 6","pages":"605-9"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36254825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zafer Gundogdu, Ismail Demirel, Mustafa Kemal Bayar, Zeynep Ozkan, Serpil Bayindir, Fatma Kocyigit, Onur Hanbeyoglu, Mustafa Kahraman
{"title":"Dose-Dependent Anti-Inflammatory Effect of Ketamine in Liver Ischemia-Reperfusion Injury.","authors":"Zafer Gundogdu, Ismail Demirel, Mustafa Kemal Bayar, Zeynep Ozkan, Serpil Bayindir, Fatma Kocyigit, Onur Hanbeyoglu, Mustafa Kahraman","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Hepatic ischemia-reperfusion (I/R) injury is commonly observed in severe\u0000sepsis, hemorrhagic shock, liver transplantation, hepatic resection, and major trauma. Ketamine\u0000suppresses the production of cytokines, such as IL-6 and TNF-α, via NF-κB inhibition. We\u0000investigated the anti-inflammatory effects of ketamine in liver I/R injury.</p><p><strong>Materials and methods: </strong>Female Wistar-Albino rats (n = 18), weighing 150-200g, were\u0000divided into three groups (n = 6 each). Group I underwent reperfusion for 4h following 30 min\u0000of ischemia. Group II received 2.5 mg/kg ketamine IM following 30 min of ischemia and 4h of\u0000reperfusion and Group III received 10 mg/kg ketamine IM following 30 min of ischemia and 4h of\u0000reperfusion. Blood samples were obtained before and after ischemia and reperfusion. MDA, AST,\u0000ALT, TNF-α, IL-1β, IL-6, and NO levels were determined. Liver tissue samples were evaluated\u0000histologically.</p><p><strong>Results: </strong>Increased TNF-α, IL-1β, and IL-6 levels were observed in all groups post-ischemia\u0000versus pre-ischemia (p <0.05). The TNF-α, IL-1β, and IL-6 levels in Group III increased less than\u0000they did in Groups I and II (p <0.05). Higher MDA, NO, AST, and ALT levels were found during\u0000the ischemia and reperfusion periods compared with during the pre-ischemia period in all groups (p\u0000<0.05). The MDA, NO, AST, and ALT levels of rats that received ketamine increased less than did\u0000those of Group I (p <0.05). Significantly less injury was observed in the histopathological analysis\u0000of livers of rats administered ketamine (p <0.05).</p><p><strong>Conclusions: </strong>Ketamine showed a dose-dependent anti-inflammatory effect in I/R injury in\u0000the liver when administered after ischemia.</p>","PeriodicalId":35975,"journal":{"name":"Middle East Journal of Anesthesiology","volume":"23 6","pages":"655-663"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36254799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Post-Partum Malignant Hypertension in a Patient with Preeclampsia and Abruptio Placenta.","authors":"Anthony K Woodall, Amir O El Hassan, Alan D Kaye","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":35975,"journal":{"name":"Middle East Journal of Anesthesiology","volume":"23 6","pages":"675-77"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36254801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed Al Harbi, Jubil Thomas, Nancy Khalil Hassan, Nermeen Said Hassanin, Salah Wannous, Chadi Abouras, Ahmed Al Harthi, Vassilios Dimitrou
{"title":"Anesthetic Management of Advanced Stage Ludwig's Angina: A Case Report and Review With Emphasis on Compromised Airway Management.","authors":"Mohammed Al Harbi, Jubil Thomas, Nancy Khalil Hassan, Nermeen Said Hassanin, Salah Wannous, Chadi Abouras, Ahmed Al Harthi, Vassilios Dimitrou","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ludwig’s angina, although uncommon, remains a potentially life-threatening condition because of the risk of impending airway obstruction. Effective treatment is based on early recognition of the clinical process, with the appropriate use of parenteral antibiotics, securing the airway, and formal surgical drainage of the infection. Awake fiberoptic intubation under topical anesthesia may be the preferred method to secure the airway. Flexible nasotracheal intubation requires skill and experience. When fiberoptic bronchoscopy is not feasible, not available, or has failed, an elective awake cricothyrotomy and tracheostomy are the options. Furthermore, the introduction of newer advanced airway techniques, such as video-assissted laryngoscopy, may allow the clinician additional flexibility in nonsurgical airway management. We present a recent case of a patient with Ludwig’s angina, successfully managed at our hospital, with a brief review of airway management options.</p>","PeriodicalId":35975,"journal":{"name":"Middle East Journal of Anesthesiology","volume":"23 6","pages":"665-73"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36254803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical exposure and organization of the Critical Care rotation during the Hajj periods in 1434-1435; perspectives of Arabian Saudi Anesthesiology\u0000Program Residents.","authors":"Abdulaziz M Boker","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Background: The nature of massive mass gathering during Hajj was expected to provide a\u0000challenging and stimulating working experience for anesthesiology training program residents. An\u0000new rotation arrangement was reached between the Ministry of Health and the Saudi Commission\u0000of Health Specialties to recruit anesthesia resident to provide critical care services during the Hajj\u0000seasons in 1434 and 1435.</p><p><strong>Objectives: </strong>This study aimed to explore the perspectives of anesthesia residents on their\u0000experience working among critical care teams during Hajj seasons in 1434H and 1435H at various\u0000locations of Makkah city and Al-Mashaer.</p><p><strong>Subjects and methods: </strong>This cross-sectional study was conducted using a self-administered\u0000questionnaire distributed to all residents (n = 35) enrolled in anesthesia residency training program\u0000of the SCFHS and participated in critical care areas as locum during the Hajj seasons of 1434H and\u00001435H. Data was analyzed by using the statistical package of social science.</p><p><strong>Results: </strong>The mean score of residents agreement on being treated with respect from both\u0000nurses and administration was the highest among the surveyed item (6.13 and 6.22 respectively). It\u0000was observed that, satisfaction of the residents with the direct observations and feedback provided\u0000to them (p = 0.01), the adequacy of the services components (p = 0.01) being treated with respect\u0000by the senior doctors and nurses (p = 0.03, p = 0.002) was significantly increased in the year 1435\u0000compared to that of the year 1434. The satisfaction was generally higher in Makkah hospitals when\u0000compared to that of Al-Mashaer (Arafat and Menna) hospitals although this difference was of no statistical significance.</p><p><strong>Conclusion: </strong>Hajj critical care rotations in 1434 and 1435 were well perceived by anesthesia\u0000residents. They found them useful as they give them the chance to gain self-confidence and\u0000experience the provision of healthcare services for mass gathering sessions.</p>","PeriodicalId":35975,"journal":{"name":"Middle East Journal of Anesthesiology","volume":"23 6","pages":"639-45"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36254826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}