Kasia Koziol-Dube, Georgine Burke, Francis Dimario
{"title":"A Study of Self-Regulated Learning of Child Neurology for Medical Students.","authors":"Kasia Koziol-Dube, Georgine Burke, Francis Dimario","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>Compare medical student preferences and outcomes after engaging two child neurology clinical scenarios with different feedback formats.</p><p><strong>Methods: </strong>After IRB exemption, online case sce- narios were presented with periodic multiple choice questions. Cases provided immediate pro- grammed feedback (IPF), or immediate in-depth programmed feedback (IDPF). Anonymous sur- veys collected datafrom students. Resultswere then tabulated and analyzed.</p><p><strong>Results: </strong>Sixty-five of 240 eligible (27%) second-, third-, and fourth-year medical students partici- pated. 'he modest-depth IPF format was preferred by 83% (54/65) of students. The cases did increase interest in child neurology significantly for second- and fourth-year students (P < .01). Students' scores increased significantly in relation to the number of IDPF links accessed (P < .01). Students who were self-characterized as internally motivated were significantly more likely to access in-depth feedback (P < .008).</p><p><strong>Conclusion: </strong>Self-regulated learning can be developed, as can an interest in child neurology, when scenarios are offered early in medical training.</p>","PeriodicalId":35577,"journal":{"name":"Connecticut Medicine","volume":"80 10","pages":"581-584"},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36218416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Coccidioides Immitis Infection with Involvement of the Airway.","authors":"Joseph H Pitcher, Jonathan B Zuckerman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Coccidioides immitis is a fungus endemic to the southwest United States and can present as an asymptomatic infection, acute pneumonia, chronic progressive pneumonia, or disseminated extrapulmonary infection which most commonly involves the skin, lymph nodes, bones, joints, or meninges. Diagnosis can be made by serologic testing or by biopsy or culture of affected tissue. Acute pneumonia due to fungi cannot be readily distinguished from bacterial pneumonia without specific diagnostic testing. Occasionally, endobronchial/tracheal lesions can be found on bronchoscopy in patients with fungal pneumonia, and when present, should raise suspicion for this entity. We present a case of acute pneumonia due to C. immitis in a non-endemic region thatwas rapidly diagnosed by biopsy of an endobronchial excrescence. We discuss previous reports of airway involvement in fungal infections and the importance of direct discussion with a pathologist when attempting to identify regionally uncommon organisms.</p>","PeriodicalId":35577,"journal":{"name":"Connecticut Medicine","volume":"80 9","pages":"539-541"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36107472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retroperitoneal, Psoas, and Scrotal Abscesses Due to an Uncommon Organism - Aggregatibacter aphrophilus: Case Report and Review of Literature.","authors":"Arushi Khurana, N Gurukripa Kowlgi, Edgar R Naut","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Aggregatibacter aphrophilus is an uncommon cause of vertebral infections and its complications are infrequently seen. We believe ours is the first reported case of scrotal abscess as a complication of vertebral osteomyelitis. We have also reviewed nine cases with complications similar to this report. Epidural abscess is the most commonly found complication, having been reported in six patients, followed closely by psoas abscess, which was seen in five patients. All except one patient underwent surgical drainage, with all patients showing complete resolution of infection.</p>","PeriodicalId":35577,"journal":{"name":"Connecticut Medicine","volume":"80 9","pages":"543-547"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36107473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Shedding a Brighter Light on Physician-Assisted Suicide.","authors":"Robert D Russo","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":35577,"journal":{"name":"Connecticut Medicine","volume":"80 9","pages":"562-563"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36108379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Del Rosario, Henry Tsai, Constantin A Dasanu
{"title":"Multicentric Neuroendocrine Carcinoma of the Breast Presenting with Multiple Osteolytic Bone Metastases.","authors":"Michael Del Rosario, Henry Tsai, Constantin A Dasanu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An uncommon subtype of breast cancer, primary neuroendocrine carcinoma of the breast (NECB), usually presents as a single nodule arising in the breast tissue. Distant metastases at presentation are rare. Optimal management of advanced disease is still debated, given the lack of evidence stemming from clinical trials. We describe a patient who presented with clinically aggressive, multicentric NECB with multiple metastatic lytic bone lesions. Ihe disease responded to systemic therapy with an oral aromatase inhibitor and monthly biphosphonate infusions. We further review the existing literature on this intriguing clinicopathologic entity.</p>","PeriodicalId":35577,"journal":{"name":"Connecticut Medicine","volume":"80 9","pages":"525-528"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36107468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clear Cell Adenocarcinoma of the Lung Mimicking Clear Cell Renal Cell Carcinoma.","authors":"Daniel H Wiznia, Julie Leviter","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We present an unusual manifestation of a malignancy in a 61-year-old female who presented clinically and cytologically with what appeared to be clear cell renal cell carcinoma, but was found with immunohistochemistry to be clear cell adenocarcinoma of the lung. The patient presented with CT imaging demonstrating a mass in the left kidney, and cytologically, the tumor cells had high nuclear grade and clear cytoplasm. However, immunohistochemically, a positive TTF-1 nuclear stain and CK7+/CK20- profile demonstrated that these cells were of lung primary. The patient did not respond to a round of carboplatin and pemetrexed, and the patient was discharged to a hospice for pain management and palliative care.</p>","PeriodicalId":35577,"journal":{"name":"Connecticut Medicine","volume":"80 9","pages":"537-538"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36107471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mirela Nicolescu, Kristin Logee, Rafael A Pacheco, Ranadeep Mandhadi
{"title":"Extracranial Giant Cell Arteritis - A Distinctive Subtype.","authors":"Mirela Nicolescu, Kristin Logee, Rafael A Pacheco, Ranadeep Mandhadi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Giant cell arteritis (GCA) is a chronic vasculitis, characterized by inflammation of large- and medium-sized arteries, primarily affecting the external carotid artery and its branches, especially the superficial temporal artery. We describe a series of three cases of \"extracranial GCA\" involving the aorta and its branches in the absence of classical cranial arteritis symptoms at the onset. Because of the paucity of disease-specific manifestations and its variability, extracranial GCA can be an overlooked clinical entity. Our clinical series illustrates that early recognition can be challenging but critical in preventing potentially devastating complications.</p>","PeriodicalId":35577,"journal":{"name":"Connecticut Medicine","volume":"80 9","pages":"553-557"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36107475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Syed Amal Hussnain, Scott Ketner, Patrick A Coady, Ninani Kombo, Kristen Nwanyanwu
{"title":"Ocular Syphilis Presenting as Bilateral Acute Retinal Necrosis in an Immunocompetent Host.","authors":"Syed Amal Hussnain, Scott Ketner, Patrick A Coady, Ninani Kombo, Kristen Nwanyanwu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Given the recent rise in reported cases of syphilis, clinicians must maintain a high index of suspicion for this great masquerader when evaluating patients with symptoms and signs of ocular inflammation. Ocular syphilis can present a diagnostic dilemma for ophthalmologists due to its myriad ofmanifestations. We report a case of ocular syphilis presenting as bilateral acute retinal necrosis (BARN) that we recently saw in Connecticut and review clinical signs, appropriate serum testing sequence, and specialized ophthalmic testing, as well as treatment of ocular syphilis.</p>","PeriodicalId":35577,"journal":{"name":"Connecticut Medicine","volume":"80 9","pages":"533-536"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36107470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lovely Chhabra, N Gurukripa Kowlgi, David H Spodick
{"title":"Colchicine In Epistenocardiac Pericarditis.","authors":"Lovely Chhabra, N Gurukripa Kowlgi, David H Spodick","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Epistenocardiac pericarditis (EP) is a rare form of pericarditis which occurs in the early period after a myocardial infarction (MI) and is commonly regionalized to the area of infarction. The preferred treatment for EP is high-dose oral aspirin, given the compelling indication for aspirin use in the post-MI setting; however, high-dose aspirin use may be prohibitive in certain clinical situations such as with concomitant use of newer antiplatelet agents like ticagrelor. The treatment option with colchicine remains an alternative; however the efficacy of colchicine in EP is not well established. We herewith describe a case series of 11 patients with EP who were treated with colchicine.</p>","PeriodicalId":35577,"journal":{"name":"Connecticut Medicine","volume":"80 9","pages":"549-551"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36107474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Refractory Small Cell Carcinoma of the Ovary - Hypercalcemic Type (SCCOHT) Treated with Romidepsin and Topotecan: A Case Report and Review of the Literature.","authors":"Vinay Rao, Frank Bauer, James J Vredenburgh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT), is a rare yet highly aggressive malignancy with a poor prognosis. Currently, there are no SCCOHT treatment guidelines. After surgery, many patients with SCCOHT receive adjuvant cisplatin and etoposide (CE), based on its efficacy in small cell lung cancer (SCLC). Nonetheless, CE-refractory SCCOHT is still common. Novel therapies (ie, histone deacetylase [HDAC] inhibitors) are being studied as they may target abnormal chromatin remodeling known to be associated with SCCOHT. We present the case of a 21-year-old female with Stage IC SCCOHT status after unilateral oophorectomy. Despite adjuvant CE, the patient developed disease progression. This is the first case report of a patient with CE-refractory SCCOHT treated with second-line topotecan (a topoisomerase-1 inhibitor) and romidepsin (an HDAC inhibitor). Although our patient's SCCOHT further progressed and lead to her death, her story highlights the importance of discovering better therapeutic targets for the treatment of SCCOHT.</p>","PeriodicalId":35577,"journal":{"name":"Connecticut Medicine","volume":"80 9","pages":"529-532"},"PeriodicalIF":0.0,"publicationDate":"2016-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36107469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}