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Primary HIV infection during chronic treatment with imatinib: impact on infection dynamics 伊马替尼慢性治疗期间的原发性艾滋病毒感染：对感染动态的影响
AIDS (London, England) Pub Date : 2024-07-11 DOI: 10.1097/QAD.0000000000003942
Giorgio Bozzi, Matteo Centazzo, Susanna Scaglioni, Giacomo M. Butta, Paola Saltini, Arianna Liparoti, Elena Trombetta, D. Prati, Andrea Gori, A. Bandera, Lara Manganaro
{"title":"Primary HIV infection during chronic treatment with imatinib: impact on infection dynamics","authors":"Giorgio Bozzi, Matteo Centazzo, Susanna Scaglioni, Giacomo M. Butta, Paola Saltini, Arianna Liparoti, Elena Trombetta, D. Prati, Andrea Gori, A. Bandera, Lara Manganaro","doi":"10.1097/QAD.0000000000003942","DOIUrl":"https://doi.org/10.1097/QAD.0000000000003942","url":null,"abstract":"","PeriodicalId":355297,"journal":{"name":"AIDS (London, England)","volume":"128 38","pages":"1601 - 1604"},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141656345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coronavirus disease 2019 outcomes in a population-based cohort of people with HIV and a matched cohort of people without HIV during Omicron variant waves 以人群为基础的艾滋病毒感染者队列和匹配的非艾滋病毒感染者队列在 Omicron 变体波期间的 2019 年冠状病毒疾病结果
AIDS (London, England) Pub Date : 2024-07-11 DOI: 10.1097/QAD.0000000000003922
Catharine Chambers, Curtis L. Cooper, Abigail E. Kroch, S. Buchan, Claire E. Kendall, Jeffrey C. Kwong, Rahim Moideddin, Lena Nguyen, Gordon Arbess, Anita C. Benoit, Cecilia T. Costiniuk, Muluba Habanyama, N. Janjua, Marc-André Langlois, John McCullagh, Lawrence Mbuagbaw, N. Moqueet, Devan Nambiar, Sergio Rueda, H. Samji, Vanessa Tran, Sharon Walmsley, Aslam H Anis, A. Burchell
{"title":"Coronavirus disease 2019 outcomes in a population-based cohort of people with HIV and a matched cohort of people without HIV during Omicron variant waves","authors":"Catharine Chambers, Curtis L. Cooper, Abigail E. Kroch, S. Buchan, Claire E. Kendall, Jeffrey C. Kwong, Rahim Moideddin, Lena Nguyen, Gordon Arbess, Anita C. Benoit, Cecilia T. Costiniuk, Muluba Habanyama, N. Janjua, Marc-André Langlois, John McCullagh, Lawrence Mbuagbaw, N. Moqueet, Devan Nambiar, Sergio Rueda, H. Samji, Vanessa Tran, Sharon Walmsley, Aslam H Anis, A. Burchell","doi":"10.1097/QAD.0000000000003922","DOIUrl":"https://doi.org/10.1097/QAD.0000000000003922","url":null,"abstract":"We found that rates of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing and reverse transcriptase (RT)-PCR-confirmed infection were approximately 50% higher in a population-based cohort of people with HIV compared with a matched cohort of people without HIV during the Omicron era (2 January 2022 to 31 March 2023) in Ontario, Canada, after controlling for age, sex, residential census tract, and country of birth. Rates of coronavirus disease 2019 (COVID-19)-related hospitalization and/or death were more than double. Differences persisted independent of vaccination, healthcare access, and COVID-19 diagnosis.","PeriodicalId":355297,"journal":{"name":"AIDS (London, England)","volume":"85 22","pages":"1597 - 1600"},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141657922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vespers: A nursing origin story set in the dawn of the HIV pandemic 晚祷一个以艾滋病毒大流行初期为背景的护理起源故事
AIDS (London, England) Pub Date : 2024-04-04 DOI: 10.1097/QAD.0000000000003873
Emily Anne Barr
{"title":"Vespers: A nursing origin story set in the dawn of the HIV pandemic","authors":"Emily Anne Barr","doi":"10.1097/QAD.0000000000003873","DOIUrl":"https://doi.org/10.1097/QAD.0000000000003873","url":null,"abstract":"","PeriodicalId":355297,"journal":{"name":"AIDS (London, England)","volume":"12 26","pages":"925 - 927"},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140745705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Presence of the M184I mutation after short-term exposure to azvudine for COVID-19 in people living with HIV HIV感染者短期接触azvudine治疗COVID-19后M184I突变的存在
AIDS (London, England) Pub Date : 2023-06-01 DOI: 10.1097/QAD.0000000000003564
Rui Jiang, Jianjun Sun, Bihe Zhao, Ren-fang Zhang, Li Liu, Jun Chen
{"title":"Presence of the M184I mutation after short-term exposure to azvudine for COVID-19 in people living with HIV","authors":"Rui Jiang, Jianjun Sun, Bihe Zhao, Ren-fang Zhang, Li Liu, Jun Chen","doi":"10.1097/QAD.0000000000003564","DOIUrl":"https://doi.org/10.1097/QAD.0000000000003564","url":null,"abstract":"Azvudine is a nucleoside analog that inhibits HIV-1 RNA-dependent RNA polymerase and is also an agent against SARS-CoV-2 [1]. It was first approved in China in July 2022 as the treatment for COVID-19 [2] and then approved in Russia in February 2023. The reverse transcriptase M184V/I mutation has historically been common in regimens that contain lamivudine (3TC) or emtricitabine (FTC) [3]. An in-vitro study demonstrated that M184I is the key mutation in azvudine treatment [4]. Here, we report M184I mutation in five HIV-1 individuals who take azvudine before initiating antiretroviral therapy (ART) in Shanghai Public Health Clinical Center (SPHCC), China, as summarized in Table 1. Genotypic resistance testing (GRT) was performed in these individuals according to our previously established protocols [5].","PeriodicalId":355297,"journal":{"name":"AIDS (London, England)","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"118533782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glottic Kaposi's sarcoma 声门卡波西肉瘤
AIDS (London, England) Pub Date : 2023-06-01 DOI: 10.1097/QAD.0000000000003559
Yong Xie, Chuan-Hui Wang, Qi An, Dongmei Wang
{"title":"Glottic Kaposi's sarcoma","authors":"Yong Xie, Chuan-Hui Wang, Qi An, Dongmei Wang","doi":"10.1097/QAD.0000000000003559","DOIUrl":"https://doi.org/10.1097/QAD.0000000000003559","url":null,"abstract":"Kaposi’s sarcoma was first described by the Hungarian dermatologist Moritz Kaposi in 1872. This mysterious vascular tumor has since received increasing attention, especially after its association with AIDS was discovered in 1981. Kaposi’s sarcoma is an indicative disease of AIDS, which is clinically divided into four forms: the classic (Mediterranean), endemic (African), epidemic (HIV/ AIDS-associated), and iatrogenic (transplant-related). All four types share the same causative virus but have distinct epidemiological and clinical presentations [1,2]. Kaposi’s sarcoma is now considered as a low-grade vascular tumor and is caused by Kaposi’s sarcoma herpesvirus/human herpesvirus-8 (KSHV/HHV-8) infection [3,4]. It usually involves the skin, lymphatic system and viscera, most notably the respiratory and gastrointestinal tracts [5–7], whereas involvement of the glottis alone is rare. In particular, acute laryngeal obstruction occurs when Kaposi’s sarcoma completely obstructs the glottis, which is life-threatening. This report summarized the clinical diagnosis and treatment of a case of AIDS complicated with glottic Kaposi’s sarcoma.","PeriodicalId":355297,"journal":{"name":"AIDS (London, England)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120437900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Global variations in mortality in adults after initiating antiretroviral treatment: an updated analysis of the International epidemiology Databases to Evaluate AIDS cohort collaboration 开始抗逆转录病毒治疗后成人死亡率的全球变化:国际流行病学数据库评估艾滋病队列合作的最新分析
AIDS (London, England) Pub Date : 2019-12-03 DOI: 10.1097/QAD.0000000000002358
L. Johnson, N. Anderegg, E. Zaniewski, J. Eaton, Peter F. Rebeiro, G. Carriquiry, D. Nash, M. Yotebieng, D. Ekouevi, C. Holmes, J. Choi, A. Jiamsakul, G. Bakoyannis, K. Althoff, A. Sohn, C. Yiannoutsos, M. Egger
{"title":"Global variations in mortality in adults after initiating antiretroviral treatment: an updated analysis of the International epidemiology Databases to Evaluate AIDS cohort collaboration","authors":"L. Johnson, N. Anderegg, E. Zaniewski, J. Eaton, Peter F. Rebeiro, G. Carriquiry, D. Nash, M. Yotebieng, D. Ekouevi, C. Holmes, J. Choi, A. Jiamsakul, G. Bakoyannis, K. Althoff, A. Sohn, C. Yiannoutsos, M. Egger","doi":"10.1097/QAD.0000000000002358","DOIUrl":"https://doi.org/10.1097/QAD.0000000000002358","url":null,"abstract":"Supplemental Digital Content is available in the text","PeriodicalId":355297,"journal":{"name":"AIDS (London, England)","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133166846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Associations between recent thymic emigrants and CD4+ T-cell recovery after short-term antiretroviral therapy initiation 近期胸腺迁移与短期抗逆转录病毒治疗开始后CD4+ t细胞恢复之间的关系
AIDS (London, England) Pub Date : 2019-12-02 DOI: 10.1097/QAD.0000000000002458
O. Briceño, Monserrat Chávez-Torres, A. Peralta-Prado, D. Garrido-Rodríguez, Karla A Romero-Mora, Sandra Pinto-Cardoso, G. Reyes-Terán
{"title":"Associations between recent thymic emigrants and CD4+ T-cell recovery after short-term antiretroviral therapy initiation","authors":"O. Briceño, Monserrat Chávez-Torres, A. Peralta-Prado, D. Garrido-Rodríguez, Karla A Romero-Mora, Sandra Pinto-Cardoso, G. Reyes-Terán","doi":"10.1097/QAD.0000000000002458","DOIUrl":"https://doi.org/10.1097/QAD.0000000000002458","url":null,"abstract":"Supplemental Digital Content is available in the text","PeriodicalId":355297,"journal":{"name":"AIDS (London, England)","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115986203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Summarizing the results and methods of the 2019 Joint United Nations Programme on HIV/AIDS HIV estimates 总结2019年联合国艾滋病毒/艾滋病联合规划署艾滋病毒估计数的结果和方法
AIDS (London, England) Pub Date : 2019-11-12 DOI: 10.1097/QAD.0000000000002440
Kelsey K Case, L. Johnson, M. Mahy, K. Marsh, V. Supervie, J. Eaton
{"title":"Summarizing the results and methods of the 2019 Joint United Nations Programme on HIV/AIDS HIV estimates","authors":"Kelsey K Case, L. Johnson, M. Mahy, K. Marsh, V. Supervie, J. Eaton","doi":"10.1097/QAD.0000000000002440","DOIUrl":"https://doi.org/10.1097/QAD.0000000000002440","url":null,"abstract":"UNAIDS and other partners provide support to countries to develop estimates of HIV and related indicators on an annual basis. These estimates are used to monitor epidemic trends, guide program planning and resource allocation, and inform policy decision-making. The collection of articles in this AIDS supplement provide the headline results for the 2019 UNAIDS estimates and describe the new developments in the methods used to produce these estimates.","PeriodicalId":355297,"journal":{"name":"AIDS (London, England)","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115082784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 34
The Estimation and Projection Package Age-Sex Model and the r-hybrid model: new tools for estimating HIV incidence trends in sub-Saharan Africa 估计和预测包年龄-性别模型和r-混合模型:估计撒哈拉以南非洲艾滋病毒发病率趋势的新工具
AIDS (London, England) Pub Date : 2019-11-12 DOI: 10.1097/QAD.0000000000002437
J. Eaton, T. Brown, Robert Puckett, R. Glaubius, K. Mutai, L. Bao, J. Salomon, J. Stover, M. Mahy, T. Hallett
{"title":"The Estimation and Projection Package Age-Sex Model and the r-hybrid model: new tools for estimating HIV incidence trends in sub-Saharan Africa","authors":"J. Eaton, T. Brown, Robert Puckett, R. Glaubius, K. Mutai, L. Bao, J. Salomon, J. Stover, M. Mahy, T. Hallett","doi":"10.1097/QAD.0000000000002437","DOIUrl":"https://doi.org/10.1097/QAD.0000000000002437","url":null,"abstract":"Supplemental Digital Content is available in the text","PeriodicalId":355297,"journal":{"name":"AIDS (London, England)","volume":"207 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121543792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
Parameter estimates for trends and patterns of excess mortality among persons on antiretroviral therapy in high-income European settings 高收入欧洲环境中抗逆转录病毒治疗人群死亡率过高趋势和模式的参数估计
AIDS (London, England) Pub Date : 2019-11-11 DOI: 10.1097/QAD.0000000000002387
A. Trickey, A. Sighem, J. Stover, S. Abgrall, S. Abgrall, S. Grabar, Fabrice Bonnet, Fabrice Bonnet, J. Berenguer, C. Wyen, J. Casabona, A. Monforte, M. Cavassini, J. Amo, R. Zangerle, M. Gill, N. Obel, J. Sterne, M. May
{"title":"Parameter estimates for trends and patterns of excess mortality among persons on antiretroviral therapy in high-income European settings","authors":"A. Trickey, A. Sighem, J. Stover, S. Abgrall, S. Abgrall, S. Grabar, Fabrice Bonnet, Fabrice Bonnet, J. Berenguer, C. Wyen, J. Casabona, A. Monforte, M. Cavassini, J. Amo, R. Zangerle, M. Gill, N. Obel, J. Sterne, M. May","doi":"10.1097/QAD.0000000000002387","DOIUrl":"https://doi.org/10.1097/QAD.0000000000002387","url":null,"abstract":"Supplemental Digital Content is available in the text","PeriodicalId":355297,"journal":{"name":"AIDS (London, England)","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131072513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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