Saratov Journal of Medical Scientific Research最新文献

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Professor Galina N. Maslyakova (to the 65th birth anniversary) Galina N. Maslyakova教授(致65周年诞辰)
Saratov Journal of Medical Scientific Research Pub Date : 2023-03-31 DOI: 10.15275/ssmj1901096
N. Navolokin, A. Mylnikov, A. Bucharskaya, V. Popkov
{"title":"Professor Galina N. Maslyakova (to the 65th birth anniversary)","authors":"N. Navolokin, A. Mylnikov, A. Bucharskaya, V. Popkov","doi":"10.15275/ssmj1901096","DOIUrl":"https://doi.org/10.15275/ssmj1901096","url":null,"abstract":"The article presents the professional biography of the famous scientist-pathologist, Doctor of Medicine, Professor Galina Nikiforovna Maslyakova, reflecting her activity as a scientist, teacher and organizer at Saratov State Medical University named after V. I. Razumovsky","PeriodicalId":354475,"journal":{"name":"Saratov Journal of Medical Scientific Research","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134249913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical features of arterial hypertension in patients with mild and moderate COVID-19 轻中度COVID-19患者动脉高血压的临床特征
Saratov Journal of Medical Scientific Research Pub Date : 2023-03-31 DOI: 10.15275/ssmj1901046
A. Ryabova, Tatiana N. Guzenko, Tatyana G. Shapovalova, A. Bykova, M. M. Shashina, Angelina V. Andriyanova
{"title":"Clinical features of arterial hypertension in patients with mild and moderate COVID-19","authors":"A. Ryabova, Tatiana N. Guzenko, Tatyana G. Shapovalova, A. Bykova, M. M. Shashina, Angelina V. Andriyanova","doi":"10.15275/ssmj1901046","DOIUrl":"https://doi.org/10.15275/ssmj1901046","url":null,"abstract":"Objective: to clarify the clinical and diagnostic features of arterial hypertension in patients with mild and moderate forms of COVID-19, taking into account the elapsed time. Material and methods. We examined 116 patients aged 44-60 years who were admitted to the hospital with uncontrolled stage 2 arterial hypertension, 96 of them had mild and moderate COVID-19. The patients were divided into two groups: the first group up to 12 weeks after suffering COVID-19 and the second group after 12 weeks. The examination included echocardiography and ambulatory blood pressure (BP) monitoring. Results. In post-COVID-19 patients, the ratio of daytime to nighttime systolic BP was statistically significantly lower than in disease-free patients (p <0,001, p1 =0,015). There was a decrease in the daily BP index in the group 1 and group 2 (11.6±0.8% and 12.2±1.2%, respectively, p=0,001). Among patients after COVID-19, non-dippers were detected, more often in group 1 (9 people (17.6%) versus 2 people (4.4%) (x2=4.18, p=0.042). Conclusion. Arterial hypertension in patients who underwent mild and moderate COVID-19 was characterized by an insufficient decrease in systolic blood pressure at night, the presence of non-dippers with positive dynamics after 12 weeks from the onset of the infectious process.","PeriodicalId":354475,"journal":{"name":"Saratov Journal of Medical Scientific Research","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115111744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inflammation, hypoxia and sclerosis as the major modulators of endometrioid cyst evolution 炎症、缺氧和硬化症是子宫内膜样囊肿演变的主要调节因子
Saratov Journal of Medical Scientific Research Pub Date : 2023-03-31 DOI: 10.15275/ssmj1901083
R. V. Ukrainets, Yuliya S. Korneva, S.Yu. Abrosimov
{"title":"Inflammation, hypoxia and sclerosis as the major modulators of endometrioid cyst evolution","authors":"R. V. Ukrainets, Yuliya S. Korneva, S.Yu. Abrosimov","doi":"10.15275/ssmj1901083","DOIUrl":"https://doi.org/10.15275/ssmj1901083","url":null,"abstract":"Objective: to estimate the peculiarities of cellular infiltrate of endometrioid ovarian cysts (EC) at various morphological stages of their formation (during evolution). Material and methods. 57 patients with histologically verified diagnosis of ovarian EC were studied; morphologically, endometrioid cysts were divided into types conventionally designated as \"immature\", \"mature\" and \"old\". Inflammatory cells were counted in the EC wall. Results. In the tissues of the \"immature\" EC, the underlying fibrous layer is represented by loose connective tissue, with a small number of granulocytes, single siderophages. An increase in the number of granulocytes in the fibrous layer along the border of the EC tissue (/-/=17.10; p<0.001; \"young\" — 8566.0 \"mature\" — 9719.0), as well as an increase in the number of lymphocytes in the stroma of the endometrioid lining (/-/=38.03; p<0.001; \"young\" — 6579.0; \"mature\" -11156.5) leads to a gradual compaction of the fibrous layer, that is the onset of a stage of \"mature\" endometrioid cyst. Violation of the blood supply to heterotopia leads to depletion of the macrophage pool due to the polarization of macrophages with an increase in the number of siderophages, that adversely affects the state of endometrioid heterotopia in the form of a decrease in almost all cells types: lymphocytes ofthe endometrioid stroma lining (/-/=38.03; p<0.001; \"mature\" — 11156.5; \"old\" — 6574.5); neutrophils of the endometrioid stroma lining (H=13.25; p=0.001; \"mature\" — 9199.5; \"old\" — 6136.0), neutrophils ofthe underlying fibrous layer (/-/=17.10; p<0.001; \"mature\" — 9719.0; \"old\" — 6025.0). Conclusion. The obtained data allow us to talk about the formation of a morphological picture ofthe \"old\" EC. The change of an acute inflammatory reaction to a chronic one with an outcome in sclerosis facilitetes hypoxia, being the main modulators of the evolution ofthe ovarian EC.","PeriodicalId":354475,"journal":{"name":"Saratov Journal of Medical Scientific Research","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126009962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of a brain abscess after a new coronavirus infection (COVID-19) (clinical case) 新型冠状病毒感染(COVID-19)后脑脓肿的治疗(临床一例)
Saratov Journal of Medical Scientific Research Pub Date : 2023-03-31 DOI: 10.15275/ssmj1901026
Dmitry V. Vakatov, Artyom A. Fomenko, Inna N. Bagretsova, Alexander V. Gorozhanin, Vladimir A. Chekhonatskiy
{"title":"Treatment of a brain abscess after a new coronavirus infection (COVID-19) (clinical case)","authors":"Dmitry V. Vakatov, Artyom A. Fomenko, Inna N. Bagretsova, Alexander V. Gorozhanin, Vladimir A. Chekhonatskiy","doi":"10.15275/ssmj1901026","DOIUrl":"https://doi.org/10.15275/ssmj1901026","url":null,"abstract":"Objective: to demonstrate the diagnostic features and successful outcome of the combined treatment of a temporoparietal abscess in the left cerebral hemisphere after a patient underwent COVID-19. The choice of a technique for surgical treatment of a brain abscess formed after COVID-19 is very difficult in view of the possible development of secondary hemorrhagic and infectious complications in such patients in the postoperative period. In the presented clinical case, the surgical manual was chosen in the volume of closed external drainage of the abscess cavity using a surgical navigation station and sowing on microflora. In combination with well-chosen antibacterial therapy, this made it possible to reduce the risk of complications, achieve early activation of the patient, and reduce the time of medical and social rehabilitation.","PeriodicalId":354475,"journal":{"name":"Saratov Journal of Medical Scientific Research","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132373504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Admission of medical university students to medical activities 招收医科大学学生参加医学活动
Saratov Journal of Medical Scientific Research Pub Date : 2023-03-31 DOI: 10.15275/ssmj1901077
I. G. Novokreshchenova, I. V. Novokreshchenov, Viktoriya V. Chunakova, N. Semikina, Liliya M. Aranovich
{"title":"Admission of medical university students to medical activities","authors":"I. G. Novokreshchenova, I. V. Novokreshchenov, Viktoriya V. Chunakova, N. Semikina, Liliya M. Aranovich","doi":"10.15275/ssmj1901077","DOIUrl":"https://doi.org/10.15275/ssmj1901077","url":null,"abstract":"Objective: to identify trends students' attitudes to medical activities prior to completing their studies at a medical university. Material and methods. A longitudinal study of the opinion of medical university students was conducted. By the method of questioning with the help of author's questionnaires (two types of questionnaires with 15 questions, adapted to the tasks of the research stages). At the 1st stage, students of those training courses were surveyed, after which it is possible to obtain admission to medical activities as specialists with secondary medical or secondary pharmaceutical education (n=634); at the 2nd stage — students of those training courses who had the opportunity to work on the basis of the received admission (n=586). Results. There was a significant increase in students' awareness of the possibility to implement medical practice as nursing professionals having obtained an admission (from 59.3% to 84.3% of respondents). There were revealed the dominant motives to receive an admission: to get working experience for further professional practice or for residency admission (52.2% and 56.1% out of 100 respondents at the first and second stages of the survey respectively), to apply/work out the acquired competencies in practice in real conditions (42.3% and 34.3% out of 100 respondents respectively). The refore some undergraduates were not prone to obtain an admission and that attitude was explained by the difficulty of combining studies and work (60.1 % out of 100 respondents). Conclusion. Along with raising awareness of students and obtaining admission of 35.5% of students, the proportion of students who do not want to get admission to medical activities classes before completing their studies is increasing.","PeriodicalId":354475,"journal":{"name":"Saratov Journal of Medical Scientific Research","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133694786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experience of curation of patients with subarachnoid hemorrhage in the Krasnoyarsk Region using Regional Stroke Monitoring module 使用区域卒中监测模块治疗克拉斯诺亚尔斯克地区蛛网膜下腔出血患者的经验
Saratov Journal of Medical Scientific Research Pub Date : 2023-03-31 DOI: 10.15275/ssmj1901040
P. Shnyakin, I. A. Kazadaeva
{"title":"Experience of curation of patients with subarachnoid hemorrhage in the Krasnoyarsk Region using Regional Stroke Monitoring module","authors":"P. Shnyakin, I. A. Kazadaeva","doi":"10.15275/ssmj1901040","DOIUrl":"https://doi.org/10.15275/ssmj1901040","url":null,"abstract":"Objective: to evaluate the results of managing patients with subarachnoid hemorrhage in the Krasnoyarsk Region using the Regional Stroke Monitoring (RSM) module for the period 2014-2020. Material and methods. We analyzed 836 electronic applications from regional hospitals of the region in the RSM module for patients with subarachnoid hemorrhage for the period 2014-2020. Results. Over the seven-year period of work in the RSM module (2014-2020) it was possible to increase the number of patients with ruptured cerebral aneurysms transferred from the regions for surgery by 52.2% (from 88 patients in 2014 to 134 in 2020) and reduce the time from the admission of patients with subarachnoid hemorrhage to the regional medical institutions to their transfer to the regional vascular center for 1 day (from 1,5±0,6 days in 2014 to 0,6±0,5 days in 2020). Conclusion. In the geographically long Krasnoyarsk Region, where it is impossible to perform neurosurgical operations in most district hospitals, RSM module helps to track patients with aneurysm ruptures in real time and transfer them to the regional vascular center for surgical treatment in a timely manner, before the re-rupture or development of angiospasm.","PeriodicalId":354475,"journal":{"name":"Saratov Journal of Medical Scientific Research","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122356792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of morbidity with temporary disability in social workers according to the factors of their work 基于工作因素的社会工作者临时残疾发病分析
Saratov Journal of Medical Scientific Research Pub Date : 2023-03-31 DOI: 10.15275/ssmj1901064
I. Berezin, M. L. Sirotko, N. Belyakova, A. K. Sergeev
{"title":"Analysis of morbidity with temporary disability in social workers according to the factors of their work","authors":"I. Berezin, M. L. Sirotko, N. Belyakova, A. K. Sergeev","doi":"10.15275/ssmj1901064","DOIUrl":"https://doi.org/10.15275/ssmj1901064","url":null,"abstract":"Objective: to analyze the incidence of temporary disability and take into account the labor factors of workers in the social service sector of a large city. Material and methods. The initial data were the number of employees of the Center for Social Services for the Population \"Central\" g. o. Samara, cases and days of temporary disability for 2018-2021. According to the compiled questionnaire, a survey was conducted of 150 social workers for a subjective assessment of health disorders, factors of conditions and nature of work. Results. In 2020, compared to 2019, the number of cases of temporary disability increased by 2.8 times, in 2021 — by 2.5 times; the number of missed days increased by almost 3 times, the largest number of cases of temporary disability in 2021 was registered in the group with 5-9 years of work experience (31 out of 128 cases; 24%). When interviewing social workers for the presence of their health disorders and affecting their ability to work, the most common symptoms were those of the respiratory system (56%), the musculoskeletal system and connective tissue (16%). It was revealed that the factors of the severity of the labor process correspond to the harmful class of working conditions of degree 3.1, the factors of intensity of the labor process — the harmful class of working conditions of degree 3.2. Conclusion. The identified features of morbidity with temporary disability must be taken into account when planning and conducting treatment and preventive work with social workers.","PeriodicalId":354475,"journal":{"name":"Saratov Journal of Medical Scientific Research","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128076041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of a neural network to restore the lost surface of skull bones 应用神经网络修复颅骨表面缺损
Saratov Journal of Medical Scientific Research Pub Date : 2023-03-31 DOI: 10.15275/ssmj1901034
S. Mishinov
{"title":"Application of a neural network to restore the lost surface of skull bones","authors":"S. Mishinov","doi":"10.15275/ssmj1901034","DOIUrl":"https://doi.org/10.15275/ssmj1901034","url":null,"abstract":"Objective: to evaluate the sensitivity, specificity and accuracy of a digital algorithm based on convo-lutional neural networks to restore of bones of cranium defects. Material and methods. Neural network training was carried out as a result of 6,000 epochs on 78,000 variants of skull models with artificially generated skull injuries. The evaluation was performed on 222 DICOM series of patients computerized tomography with bones of cranium defects. Results. The indicators of sensitivity, specificity and accuracy were 95.3%, 85.5% and 79.4% respectively. A number of experiments were carried out with step-by-step sorting of three-dimensional models in order to find the reasons for the unsatisfactory skull reconstructing results. Incorrect detection of the skull defect most often occurred in the area of the facial skeleton. After excluding the series with artifacts, the average increase in metrics was 2.6%. Conclusion. Correct determination of the bone defect at the scull model (specificity) by the algorithm had the greatest impact on the surface accuracy. The maximum accuracy of the algorithm, which allows using the obtained surfaces without additional processing in a three-dimensional modeling environment, was achieved on series without the presence of artifacts during computed tomography (83.5%), as well as with defects that do not extend to the skull base (79.5%).","PeriodicalId":354475,"journal":{"name":"Saratov Journal of Medical Scientific Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130448218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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