武汉大学学报(医学版)最新文献_第5页

Infectivity of 14 patients with latent COVID-19 infection in operating room and their postoperative outcomes 14例手术室潜伏性COVID-19感染患者的感染性及术后结局分析

Medical Journal of Wuhan University Pub Date : 2020-09-15 DOI: 10.14188/J.1671-8852.2020.0212

Wating Su, S. Lei, Yifan Jia, Z. Xia, Z. Xia

{"title":"Infectivity of 14 patients with latent COVID-19 infection in operating room and their postoperative outcomes","authors":"Wating Su, S. Lei, Yifan Jia, Z. Xia, Z. Xia","doi":"10.14188/J.1671-8852.2020.0212","DOIUrl":"https://doi.org/10.14188/J.1671-8852.2020.0212","url":null,"abstract":"Objective: To analyze the infectivity of latent coronavirus disease 2019 (COVID-19) in the operating room, and describe their postoperative outcomes Methods: Fourteen surgical patients with latent SAR-CoV-2 infection in January 2020, in Renmin Hospital of Wuhan University were selected as the research objects We investigated the contact infection between medical staff and patients The general information, clinical symptoms and signs, and postoperative outcome of the patients were also analyzed Results: In the operating room, 42 healthcare workers (47 person-times in total) were isolated under medical observation after contacting with the patients At last, 3 healthcare workers were diagnosed as COVID-19 All these 14 patients were laboratory-confirmed SARS-CoV-2 infection in 3-7 days after surgery In terms of signs and symptoms, 12 patients had fever, 10 patients felt fatigue, and 9 patients had dry cough In terms of postoperative outcome, 1 patient died, 13 patients (including 1 mild, 7 general, and 5 severe cases) were transferred to the designated hospitals according to the local health committee Conclusion: Patients with SARS-CoV-2 infection are highly infectious even in the operating room environment The stress of anesthesia and operation may exacerbate the progression of COVID-19, and worsen the outcome of patients © 2020, Editorial Board of Medical Journal of Wuhan University All right reserved","PeriodicalId":35402,"journal":{"name":"Medical Journal of Wuhan University","volume":"41 1","pages":"702-705"},"PeriodicalIF":0.0,"publicationDate":"2020-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43027625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical characteristics and immune function analysis of COVID-19 新冠肺炎临床特点及免疫功能分析

Medical Journal of Wuhan University Pub Date : 2020-07-15 DOI: 10.14188/J.1671-8852.2020.0126

Zilong Lu, Ruyuan He, Wenyang Jiang, Tao Fan, Q. Geng

引用次数: 18

Clinical characteristics and CT signs of coronavirus disease 2019 (COVID-19) in the elderly 老年人2019冠状病毒病（新冠肺炎）的临床特征和CT征象

Medical Journal of Wuhan University Pub Date : 2020-07-15 DOI: 10.14188/J.1671-8852.2020.0087

Jia Cao, Jun Zhou, Xingnan Liao, Gonghao Ling, Xun Ding, Qing-yun Long

{"title":"Clinical characteristics and CT signs of coronavirus disease 2019 (COVID-19) in the elderly","authors":"Jia Cao, Jun Zhou, Xingnan Liao, Gonghao Ling, Xun Ding, Qing-yun Long","doi":"10.14188/J.1671-8852.2020.0087","DOIUrl":"https://doi.org/10.14188/J.1671-8852.2020.0087","url":null,"abstract":"The CT findings of 36 elderly patients with novel coronavirus disease 2019 (COVID-19)were analyzed to provide imaging diagnostic basis for clin diagnosis Methods: The clin date and chest CT images of 36 elderly patients with pos new coronavirus nucleic acid admitted to Zhongnan Hospital of Wuhan University were retrospectively analyzed Results:: Elderly COVID-19 patients had more underlying diseases, with more complicated clin symptoms than young patients, including fever (77 8%), cough (55 6%), and dyspnea (52 8%);CT signs are characterized by diversity and multi-focus, mainly showing the coexistence of ground-glass shadow and consolidation shadow (72 2%), mostly located in the outer lung field of bilateral lung (69 4%), and the air bronchus sign (58 3%) in the lesions COVID-19 in the elderly progresses relatively fast, and severe patients were more common, and 55 6% patients were male Conclusion:: CT images of elderly COVID-19 patients have certain characteristics Chest thin-section CT is helpful for early diagnosis and provides an effective supplement to nucleic acid detection for SARS-CoV-2","PeriodicalId":35402,"journal":{"name":"Medical Journal of Wuhan University","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47887595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Glucocorticoid application in the treatment of coronavirus disease 2019(COVID-19): the pros and cons 糖皮质激素在2019冠状病毒病（新冠肺炎）治疗中的应用：优缺点

Medical Journal of Wuhan University Pub Date : 2020-07-15 DOI: 10.14188/J.1671-8852.2020.0136

Qian Chen, M. Pei, Yao Wang, Z. Gong

引用次数: 1

Chest CT features comparison between COVID-19 and bacterial pneumonia 新型冠状病毒肺炎与细菌性肺炎的胸部CT特征比较

Medical Journal of Wuhan University Pub Date : 2020-05-15 DOI: 10.14188/J.1671-8852.2020.0086

Xingnan Liao, Jun Zhou, Jia Cao, Gonghao Ling, Xun Ding, Qing-yun Long

{"title":"Chest CT features comparison between COVID-19 and bacterial pneumonia","authors":"Xingnan Liao, Jun Zhou, Jia Cao, Gonghao Ling, Xun Ding, Qing-yun Long","doi":"10.14188/J.1671-8852.2020.0086","DOIUrl":"https://doi.org/10.14188/J.1671-8852.2020.0086","url":null,"abstract":"Objective: To improve the imaging diagnosis of novel coronavirus disease 2019 (COVID-19) by comparing the chest CT imaging characteristics between COVID-19 and bacterial pneumonia Methods: CT data of 42 COVID-19 cases from January 16 to February 18, 2020 were retrospectively analyzed, and we also compared with the CT data of 36 cases of bacterial pneumonia collected from November 27, 2017 to February 6, 2020 Results: The incidence of bilateral lobes involvement in COVID-19 group was 73 8%, which was significantly higher than that in bacterial pneumonia group (vs 41 7%, P 0 01) The incidences of ground glass shadow (95 2%), mesh shadow (31 0%), and pavement sign (26 2%) were significantly higher than those of bacterial pneumonia (77 8%, 8 3% and 0, respectively, all P 0 05) The incidences of consolidation (35 7%), and central lobular nodule or tree-bud signs (9 5%) were lower than those of bacterial pneumonia (66 7% and 47 2%, respectively, both P 0 05) Conclusion: In COVID-19 patients, more CT signs such as ground glass shadow, mesh shadow and paved appearance were found than in bacterial pneumonia ones, whereas the consolidation shadow, central lobular nodules and tree-bud signs were less common © 2020, Editorial Board of Medical Journal of Wuhan University All right reserved","PeriodicalId":35402,"journal":{"name":"Medical Journal of Wuhan University","volume":"41 1","pages":"349-352"},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49007685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Advances in the treatment of viral pneumonia 病毒性肺炎的治疗进展

Medical Journal of Wuhan University Pub Date : 2020-05-15 DOI: 10.14188/J.1671-8852.2020.6018

T. Suo, Hui Fan, Guo-zhong Chen

引用次数: 0

Research progress of antiviral drugs in coronavirus infection 冠状病毒感染抗病毒药物的研究进展

Medical Journal of Wuhan University Pub Date : 2020-05-15 DOI: 10.14188/J.1671-8852.2020.6019

Yanni Wang, Guo-zhong Chen

引用次数: 0

Severe COVID-19 complicated with pulmonary embolism: a case report and literature review 重症COVID-19合并肺栓塞1例并文献复习

Medical Journal of Wuhan University Pub Date : 2020-05-15 DOI: 10.14188/J.1671-8852.2020.0095

W. Zou, Bin Song, Xiaowei Wu

引用次数: 0

Cytoreductive Surgery Plus Hyperthermic Intraperitoneal Chemotherapy Improves Survivalin Patients with StageIIIc Ovarian Cancer 细胞减少手术加腹腔内高温化疗可提高ii期卵巢癌患者的生存率

Medical Journal of Wuhan University Pub Date : 2015-01-01 DOI: 10.14188/J.1671-8852.2015.04.015

LU Yula

引用次数: 1

Clinical characteristics of 228 hospitalized patients with COVID-19 228例新冠肺炎住院患者临床特征分析

Medical Journal of Wuhan University Pub Date : 1900-01-01 DOI: 10.14188/j.1671-8852.2020.0474

T. Wang, S. Gao, X. Bao, J. Bian

{"title":"Clinical characteristics of 228 hospitalized patients with COVID-19","authors":"T. Wang, S. Gao, X. Bao, J. Bian","doi":"10.14188/j.1671-8852.2020.0474","DOIUrl":"https://doi.org/10.14188/j.1671-8852.2020.0474","url":null,"abstract":"Objective: To describe the epidemiological and clinical features of coronavious disease 2019 (COVID-19). Methods: The data of 228 inpatients diagnosed as COVID-19 in the Third Hospital of Wuhan from January 27, 2020, to February 29, 2020 were collected, and their clinical characteristics and outcomes were analyzed. Results: The average age of inpatients was 58 years old. Common symptoms included fever (88.2%), fatigue (69.7%), and dry cough (59.2%). There were patients with gastrointestinal discomfort as the first symptom (7.9%). In severe patients, lymphocytes decreased significantly, albumin decreased, D-dimer increased, lactate dehydrogenase and creatine kinase isoenzyme increased (all P <0.05). Chest CT of all patients showed patchy shadows or frosted glass opacity of both lungs. Severe patients were more likely to have comorbidities ( P <0.05), and more likely to have complications including acute respiratory distress syndrome (ARDS) (19 cases, 8.3%), arrhythmia (13 cases, 5.7%), and shock (5 cases, 2.2%), and 7% COVID⁃19 cases were transferred to the ICU due to the worsening of the disease, and the patients' mortality rate was 4.4%. There were no specific drugs for treatment, and supportive treatment was the mainstay. Conclusion: Severe patients had differences in age of onset, underlying diseases, symptoms, laboratory tests, and complications, etc., and needed to be identified earlier. © 2021, Editorial Board of Medical Journal of Wuhan University. All right reserved.","PeriodicalId":35402,"journal":{"name":"Medical Journal of Wuhan University","volume":"42 1","pages":"709-713"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66656844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0