Hss JournalPub Date : 2023-11-01Epub Date: 2023-08-17DOI: 10.1177/15563316231193367
Michelle M McLeod, Jason S Kim, Peter Moley, Mark A Fontana, Jason Blevins, Brian Chalmers, Marcus Bamman, Mathias P Bostrom
{"title":"Arthritis Foundation/HSS Workshop on Hip Osteoarthritis, Part 4: Nonoperative Options, Machine Learning in Predicting Total Hip Arthroplasty, Robotics, and Phenotyping to Guide Precision Rehabilitation.","authors":"Michelle M McLeod, Jason S Kim, Peter Moley, Mark A Fontana, Jason Blevins, Brian Chalmers, Marcus Bamman, Mathias P Bostrom","doi":"10.1177/15563316231193367","DOIUrl":"10.1177/15563316231193367","url":null,"abstract":"<p><p>Far more publications are available for osteoarthritis of the knee than of the hip. Recognizing this research gap, the Arthritis Foundation (AF), in partnership with the Hospital for Special Surgery (HSS), convened an in-person meeting of thought leaders to review the state of the science of and clinical approaches to hip osteoarthritis. This article summarizes the recommendations gleaned from presentations given in the \"late-stage osteoarthritis\" session of the 2023 Hip Osteoarthritis Clinical Studies Conference, which took place on February 17 and 18, 2023, in New York City. It covers conservative treatment, decision-making in end-stage hip osteoarthritis, advancements in robotics, and the role of phenotyping in precision rehabilitation post-total hip arthroplasty (THA).</p>","PeriodicalId":35357,"journal":{"name":"Hss Journal","volume":"19 4","pages":"473-477"},"PeriodicalIF":1.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71486832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hss JournalPub Date : 2023-11-01Epub Date: 2023-08-23DOI: 10.1177/15563316231193404
Riccardo Lattanzi
{"title":"Methods for the Clinical Translation of Quantitative MRI for the Evaluation of Patients With Femoroacetabular Impingement.","authors":"Riccardo Lattanzi","doi":"10.1177/15563316231193404","DOIUrl":"10.1177/15563316231193404","url":null,"abstract":"","PeriodicalId":35357,"journal":{"name":"Hss Journal","volume":"19 4","pages":"442-446"},"PeriodicalIF":1.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71491210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hss JournalPub Date : 2023-11-01Epub Date: 2023-08-09DOI: 10.1177/15563316231190084
Cecilia Pascual-Garrido, Kenichi Kikuchi, John C Clohisy, Regis J O'Keefe, Tomoyuki Kamenaga
{"title":"Revealing a Natural Model of Pre-Osteoarthritis of the Hip Through Study of Femoroacetabular Impingement.","authors":"Cecilia Pascual-Garrido, Kenichi Kikuchi, John C Clohisy, Regis J O'Keefe, Tomoyuki Kamenaga","doi":"10.1177/15563316231190084","DOIUrl":"10.1177/15563316231190084","url":null,"abstract":"<p><p>Femoroacetabular impingement (FAI) is considered the mechanical cause of hip osteoarthritis (OA). Surgical intervention involves labrum repair and osteochondroplasty to remove the impingement, alleviating symptoms. Nevertheless, some patients progress to hip OA after surgery, indicating that factors other than mechanical abnormality are contributing to hip OA progression. This review article discusses our laboratory's studies on hip FAI and OA, undertaken to identify key molecular players in the progression of hip OA. Transcriptome analysis identified peroxisome proliferator activated receptor gamma (PPARγ) as a crucial molecule in early hip OA. PPARγ, widely expressed in chondrocytes, has a protective role in preventing OA, but its true mechanism remains unknown. We observed a dysregulation of DNA methyltransferase (DNMT) in the progression of hip OA, with high expression of DNMT1 and 3A and downregulation of DNMT3B. Moreover, we established that DNMT3A is the main molecule that is binding to PPARγ promoter CpG area, and hypermethylation of this area occurs during disease progression. This suggests that epigenetic changes are a main mechanism that regulates PPARγ expression. Finally, we developed a novel rabbit model of hip FAI and OA and are currently performing studies to validate our small-animal model to human FAI.</p>","PeriodicalId":35357,"journal":{"name":"Hss Journal","volume":"19 4","pages":"434-441"},"PeriodicalIF":1.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71486793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hss JournalPub Date : 2023-11-01Epub Date: 2023-08-20DOI: 10.1177/15563316231193394
Cecelia Lawrence
{"title":"Preoperative Education and Prehabilitation in Total Hip Arthroplasty Patients: A Commentary.","authors":"Cecelia Lawrence","doi":"10.1177/15563316231193394","DOIUrl":"10.1177/15563316231193394","url":null,"abstract":"","PeriodicalId":35357,"journal":{"name":"Hss Journal","volume":"19 4","pages":"507-510"},"PeriodicalIF":2.5,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71486837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hss JournalPub Date : 2023-11-01Epub Date: 2023-08-06DOI: 10.1177/15563316231189748
Jason S Kim, Rintje Agricola, Young-Jo Kim, Nancy E Lane, Michael B Millis, Amanda E Nelson, Jos Runhaar, Sandra J Shefelbine, Mathias P Bostrom
{"title":"Arthritis Foundation/HSS Workshop on Hip Osteoarthritis, Part 1: Epidemiology, Early Development, and Cohorts From Around the World.","authors":"Jason S Kim, Rintje Agricola, Young-Jo Kim, Nancy E Lane, Michael B Millis, Amanda E Nelson, Jos Runhaar, Sandra J Shefelbine, Mathias P Bostrom","doi":"10.1177/15563316231189748","DOIUrl":"10.1177/15563316231189748","url":null,"abstract":"<p><p>Far more publications are available for osteoarthritis of the knee than of the hip. Recognizing this research gap, the Arthritis Foundation, in partnership with the Hospital for Special Surgery, convened an in-person meeting of thought leaders to review the state of the science of and clinical approaches to hip osteoarthritis. This article summarizes the recommendations and clinical research gaps gleaned from 5 presentations given in the \"how hip osteoarthritis begins\" session of the 2023 Hip Osteoarthritis Clinical Studies Conference, which took place on February 17 and 18, 2023, in New York City.</p>","PeriodicalId":35357,"journal":{"name":"Hss Journal","volume":"19 4","pages":"395-401"},"PeriodicalIF":1.6,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10626936/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71486829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hss JournalPub Date : 2023-10-28DOI: 10.1177/15563316231208454
Susan Camillieri
{"title":"Does Participation in Virtual or In-Person Preoperative Education Relate to Reduced Length of Stay After Total Joint Arthroplasty?","authors":"Susan Camillieri","doi":"10.1177/15563316231208454","DOIUrl":"https://doi.org/10.1177/15563316231208454","url":null,"abstract":"Background: Advancements in surgical procedures for total joint arthroplasty (TJA) have resulted in more effective procedures with more rapid recovery. To prepare patients for surgery, many organizations offer a preoperative “joint class,” which has been associated with reduced length of stay (LOS). Virtual modes of education are increasingly favored for those having TJA. Purpose: To determine whether participation in an individually administered preoperative educational session (“Prehab”) relates to reduced LOS or increased likelihood of same-day discharge (SDD) for those undergoing TJA. Additionally, to establish whether and the virtual mode of education provision is superior or inferior to the in-person mode with regards to LOS benefits. Methods: The author conducted a case-control study of 2532 patients who had a primary or revision TJA between January 2022 and August 2022 at a single institution. Data were obtained from the electronic medical record. A total of 1118 patients attended Prehab; 1414 patients did not. Patients were included if they were over the age of 18 and had a total hip arthroplasty (THA) or total knee arthroplasty (TKA) during the study period. T-tests, chi-square χ 2 tests, and binomial logistic regression were used to evaluate the LOS and SDD outcomes for those who participated in Prehab compared with those who did not. Results: Those receiving Prehab in any form had shorter LOS than those who had not. Those receiving virtual Prehab had the shortest LOS. There was no difference in the rate of SDD for outpatient-class patients. Conclusion: Preoperative education is associated with LOS benefits to patients undergoing TJA. The virtual mode of education provision is at minimum non-inferior, and may be superior, to the in-person mode. The lack of statistically significant between-group differences for SDD outcomes may be explained by a lack of SDD-specific educational content provided during Prehab.","PeriodicalId":35357,"journal":{"name":"Hss Journal","volume":"28 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136159030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hss JournalPub Date : 2023-10-28DOI: 10.1177/15563316231208431
Sohum Patel, Leonard T. Buller
{"title":"Outpatient Hip and Knee Arthroplasty Can be Safe in Patients With Multiple Medical Comorbidities via Use of Evidence-Based Perioperative Protocols","authors":"Sohum Patel, Leonard T. Buller","doi":"10.1177/15563316231208431","DOIUrl":"https://doi.org/10.1177/15563316231208431","url":null,"abstract":"","PeriodicalId":35357,"journal":{"name":"Hss Journal","volume":"18 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136158774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hss JournalPub Date : 2023-10-28DOI: 10.1177/15563316231204231
Rex W. Lutz, Danielle Y. Ponzio, Hope S. Thalody, Harrison A. Patrizio, Miranda M. Czymek, Michael Ast, Zachary D. Post, Alvin C. Ong
{"title":"Social Risk Determinants for Successful Same Calendar Day Discharge in Total Joint Arthroplasty","authors":"Rex W. Lutz, Danielle Y. Ponzio, Hope S. Thalody, Harrison A. Patrizio, Miranda M. Czymek, Michael Ast, Zachary D. Post, Alvin C. Ong","doi":"10.1177/15563316231204231","DOIUrl":"https://doi.org/10.1177/15563316231204231","url":null,"abstract":"Background: While many studies have examined the impact of comorbidities on the success of same calendar day discharge (SCDD) in total joint arthroplasty (TJA), literature surrounding the impact of social determinants is lacking. Purpose: We sought to investigate the relationship between various social determinants and success of SCDD after primary total hip arthroplasty (THA) and total knee arthroplasty (TKA). Methods: We conducted a retrospective review of 1160 THA and 1813 TKA performed at a single academic institution between November 2020 and August 2022. Social factors including substance use, occupation, marital status, income, and participation in physical exercise were included. In addition, aspects of discharge planning were reviewed such as living situation and transportation details. Results: Overall, 952 (32%) patients had successful SCDD, whereas 2021 (68%) patients were discharged on postoperative day 1 (POD1) or greater. Successful SCDD patients were more likely to have health care (4.8% vs 2.5%) and active (5.4% vs 4.6%) rather than sedentary occupations, be married (79.6% vs 67.4%), have access to transportation (95.6% vs 92.9%), live in a higher median income area ($64,044 [16,183] vs $61,572 [14,594]), and exercise weekly (62.6% vs 23.9%). Interestingly, the successful patients had more stories in their homes (1.62 [0.56] vs 1.43 [0.53]), more stairs to enter their homes (5.19 [5.22] vs 4.60 [5.24]), lived farther from the hospital (43.3 [138.0] vs 32.0 [75.9] miles), and a higher prevalence of alcohol use (60.7% vs 44.7%) and tobacco use (19.3% vs 17.3%). Conclusion: These findings may help arthroplasty surgeons to better understand the social factors that contribute to successful SCDD in TJA patients, ultimately aiding in patient selection and preoperative counseling.","PeriodicalId":35357,"journal":{"name":"Hss Journal","volume":"293 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136158473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hss JournalPub Date : 2023-10-26DOI: 10.1177/15563316231204308
Stephanie I. Cheng, Cephas P. Swamidoss, Ellen M. Soffin
{"title":"Perioperative Acupuncture: A Novel and Necessary Addition to ERAS Pathways for Total Joint Arthroplasty","authors":"Stephanie I. Cheng, Cephas P. Swamidoss, Ellen M. Soffin","doi":"10.1177/15563316231204308","DOIUrl":"https://doi.org/10.1177/15563316231204308","url":null,"abstract":"","PeriodicalId":35357,"journal":{"name":"Hss Journal","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134908211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hss JournalPub Date : 2023-10-24DOI: 10.1177/15563316231204040
Hassaan Abdel Khalik, Manraj S. Nijjar, Jack Soeder, Darius L. Lameire, Herman Johal
{"title":"Trends and Themes in the Study of Value in Orthopedic Surgery: A Systematic Review","authors":"Hassaan Abdel Khalik, Manraj S. Nijjar, Jack Soeder, Darius L. Lameire, Herman Johal","doi":"10.1177/15563316231204040","DOIUrl":"https://doi.org/10.1177/15563316231204040","url":null,"abstract":"Background: The study of value in orthopedic surgery aims to maximize health outcomes gained per unit cost through various health economic tools but is fragmented across various subspecialties and geographies. Therefore, it is difficult to ascertain whether this research methodology is being used to its full potential across all orthopedic subspecialties and geographies. Purpose: We sought to assess the distribution of prior health economics literature in orthopedic surgery across subspecialties and geographies. The secondary aim was to identify pertinent methodologic trends that may affect the conclusions drawn. Methods: A systematic review utilizing 3 electronic databases (Medline, Embase, and Web of Science) was performed. Inclusion criteria included prior systematic reviews assessing economic analyses across all orthopedic surgery subspecialities published between 2010 and April 24, 2021. The quality of evidence was assessed using the Assessment of Multiple Systematic Review tool. Data were qualitatively analyzed. Results: In the 44 studies included, arthroplasty (36.4%) and spine (31.8%) were the most represented subspecialties. Almost half of studies originated from the United States (45.5%), followed by the United Kingdom (18.2%). Health economic models were most commonly from the perspective of the health care or hospital system (40.5%), followed by the societal perspective (23.5%), and the payer perspective (14.8%). Conclusions: The study of value in orthopedic surgery is not uniformly leveraged across all subspecialties and geographies. Methodologically, the societal perspective was inadequately represented, despite orthopedic pathologies often incurring significant indirect costs (eg, time off work, rehabilitation expenses).","PeriodicalId":35357,"journal":{"name":"Hss Journal","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135316215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}