Electrolyte and Blood Pressure最新文献_第9页

A Case of Post-radiotherapy Urethral Stricture with Spontaneous Bladder Rupture, Mimicking Obstructive Uropathy due to Cancer Metastasis. 放疗后尿道狭窄并发自发性膀胱破裂1例，模拟肿瘤转移致梗阻性尿路病变。

Electrolyte and Blood Pressure Pub Date : 2014-06-01 Epub Date: 2014-06-30 DOI: 10.5049/EBP.2014.12.1.26

Jun Young Shin, Sang Min Yoon, Hyuck Jae Choi, Si Nae Lee, Hai Bong Kim, Woo Chul Joo, Joon Ho Song, Moon-Jae Kim, Seoung Woo Lee

{"title":"A Case of Post-radiotherapy Urethral Stricture with Spontaneous Bladder Rupture, Mimicking Obstructive Uropathy due to Cancer Metastasis.","authors":"Jun Young Shin, Sang Min Yoon, Hyuck Jae Choi, Si Nae Lee, Hai Bong Kim, Woo Chul Joo, Joon Ho Song, Moon-Jae Kim, Seoung Woo Lee","doi":"10.5049/EBP.2014.12.1.26","DOIUrl":"https://doi.org/10.5049/EBP.2014.12.1.26","url":null,"abstract":"Non-traumatic, spontaneous urinary bladder rupture is a rare complication of urethral stricture. Furthermore, its symptoms are often nonspecific, and misdiagnosis is common. The authors experienced a case of urethral stricture with spontaneous bladder rupture and bilateral hydronephrosis, mimicking obstructive uropathy attributed to cancer metastasis. A 55-year-old woman was admitted with abdominal pain and distension, oliguria, and an elevated serum creatinine level. She had undergone radical hysterectomy for uterine cervical cancer and received post-operative concurrent chemoradiation therapy 13 years previously. Non-contrast enhanced computed tomography showed massive ascites and bilateral hydronephrosis. The initial diagnosis was acute kidney injury due to obstructive uropathy caused by malignant disease. After improvement of her renal function by bilateral percutaneous nephrostomy catheterization, contrast-enhanced computed tomography and a cytologic examination of ascites showed no evidence of malignancy. However, during retrograde pyelography, a severe urethral stricture was found, and subsequent cystography showed leakage of contrast into the peritoneal cavity and cystoscopy revealed a defect of the posterior bladder wall. After urethral dilatation and primary closure of the bladder wall, acute kidney injury and ascites were resolved. ","PeriodicalId":35352,"journal":{"name":"Electrolyte and Blood Pressure","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5049/EBP.2014.12.1.26","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32534324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Association between Hypophosphatemia and Cardiac Arrhythmias in the Early Stage of Sepsis: Could Phosphorus Replacement Treatment Reduce the Incidence of Arrhythmias? 败血症早期低磷血症与心律失常之间的关系：磷替代治疗能否降低心律失常的发生率？

Electrolyte and Blood Pressure Pub Date : 2014-06-01 Epub Date: 2014-06-30 DOI: 10.5049/EBP.2014.12.1.19

Andrei Schwartz, Evgeni Brotfain, Leonid Koyfman, Ruslan Kutz, Shaun E Gruenbaum, Moti Klein, Alexander Zlotnik

{"title":"Association between Hypophosphatemia and Cardiac Arrhythmias in the Early Stage of Sepsis: Could Phosphorus Replacement Treatment Reduce the Incidence of Arrhythmias?","authors":"Andrei Schwartz, Evgeni Brotfain, Leonid Koyfman, Ruslan Kutz, Shaun E Gruenbaum, Moti Klein, Alexander Zlotnik","doi":"10.5049/EBP.2014.12.1.19","DOIUrl":"10.5049/EBP.2014.12.1.19","url":null,"abstract":"It is well known that new-onset arrhythmias are common in septic patients. It is thought that hypophosphatemia in the early stages of sepsis may contribute to the development of new arrhythmias. In this study, we hypothesized that intravenous (IV) phosphorus replacement may reduce the incidence of arrhythmias in critically ill patients. 34 adult septic patients with hypophosphatemia admitted to the general intensive care unit were treated with IV phosphorus replacement per ICU protocol, and the incidence of new arrhythmias were compared with 16 patients from previously published data. IV phosphorus replacement was associated with a significantly reduced incidence of arrhythmias (38% vs. 63%, p=0.04). There were no differences in observed mortality between subgroups, which may be due to the small sample size. This study demonstrated that IV phosphorus replacement might be effective in reducing the incidence of new arrhythmias in septic patients. ","PeriodicalId":35352,"journal":{"name":"Electrolyte and Blood Pressure","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e4/6c/ebp-12-19.PMC4105385.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32532888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary salt intake and hypertension. 食盐摄入与高血压的关系

Electrolyte and Blood Pressure Pub Date : 2014-06-01 Epub Date: 2014-06-30 DOI: 10.5049/EBP.2014.12.1.7

Sung Kyu Ha

{"title":"Dietary salt intake and hypertension.","authors":"Sung Kyu Ha","doi":"10.5049/EBP.2014.12.1.7","DOIUrl":"https://doi.org/10.5049/EBP.2014.12.1.7","url":null,"abstract":"Over the past century, salt has been the subject of intense scientific research related to blood pressure elevation and cardiovascular mortalities. Moderate reduction of dietary salt intake is generally an effective measure to reduce blood pressure. However, recently some in the academic society and lay media dispute the benefits of salt restriction, pointing to inconsistent outcomes noted in some observational studies. A reduction in dietary salt from the current intake of 9-12 g/day to the recommended level of less than 5-6 g/day will have major beneficial effects on cardiovascular health along with major healthcare cost savings around the world. The World Health Organization (WHO) strongly recommended to reduce dietary salt intake as one of the top priority actions to tackle the global non-communicable disease crisis and has urged member nations to take action to reduce population wide dietary salt intake to decrease the number of deaths from hypertension, cardiovascular disease and stroke. However, some scientists still advocate the possibility of increased risk of CVD morbidity and mortality at extremes of low salt intake. Future research may inform the optimal sodium reduction strategies and intake targets for general populations. Until then, we have to continue to build consensus around the greatest benefits of salt reduction for CVD prevention, and dietary salt intake reduction strategies must remain at the top of the public health agenda. ","PeriodicalId":35352,"journal":{"name":"Electrolyte and Blood Pressure","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5049/EBP.2014.12.1.7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32532887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 219

Severe hypernatremia by excessive bamboo salt ingestion in healthy young woman. 健康青年妇女摄入过量竹盐致严重高钠血症。

Electrolyte and Blood Pressure Pub Date : 2013-12-01 Epub Date: 2013-12-31 DOI: 10.5049/EBP.2013.11.2.53

Hyun Jun Ju, Hong Jin Bae, Dae Eun Choi, Ki Ryang Na, Kang Wook Lee, Young Tai Shin

引用次数: 8

Obesity associated hypertension: new insights into mechanism. 肥胖相关高血压:机制的新见解

Electrolyte and Blood Pressure Pub Date : 2013-12-01 Epub Date: 2013-12-31 DOI: 10.5049/EBP.2013.11.2.46

Young Sun Kang

{"title":"Obesity associated hypertension: new insights into mechanism.","authors":"Young Sun Kang","doi":"10.5049/EBP.2013.11.2.46","DOIUrl":"https://doi.org/10.5049/EBP.2013.11.2.46","url":null,"abstract":"With excess nutrition, the burden of obesity is a growing problem worldwide. The imbalance between energy intake and expenditure leads to variable disorders as all major risk factors for cardiovascular disease. There are many hypothetical mechanisms to explain obesity-associated hypertension. Activation of the RAAS is a key contributing factor in obesity. Particularly, the RAAS in adipose tissue plays a crucial role in adipose tissue dysfunction and obesity-induced inflammation. The phenotypic changes of adipocytes occur into hypertrophy and an inflammatory response in an autocrine and paracrine manner to impair adipocyte function, including insulin signaling pathway. Adipose tissue produce and secretes several molecules such as leptin, resistin, adiponectin, and visfatin, as well as cytokines such as TNF-α, IL-6, MCP-1, and IL-1. These adipokines are stimulated via the intracellular signaling pathways that regulate inflammation of adipose tissue. Inflammation and oxidative stress in adipose tissue are important to interact with the microvascular endothelium in the mechanisms of obesity-associated hypertension. Increased microvascular resistance raises blood pressure. Therefore, a regulatory link between microvascular and perivascular adipose tissue inflammation and adipokine synthesis are provided to explain the mechanism of obesity-associated hypertension. ","PeriodicalId":35352,"journal":{"name":"Electrolyte and Blood Pressure","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5049/EBP.2013.11.2.46","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32173911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 124

Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. 肾素-血管紧张素-醛固酮系统在高血压发病中的最新进展。

Electrolyte and Blood Pressure Pub Date : 2013-12-01 Epub Date: 2013-12-31 DOI: 10.5049/EBP.2013.11.2.41

Ju-Young Moon

{"title":"Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension.","authors":"Ju-Young Moon","doi":"10.5049/EBP.2013.11.2.41","DOIUrl":"https://doi.org/10.5049/EBP.2013.11.2.41","url":null,"abstract":"The activation of renin-angiotensin-aldosterine system(RAAS) is one of the main pathogenesis of hypertension. All the components of RAAS are present in the kidneys at higher concentrations compared to plasma levels, and intrarenal formation of angiotensin II (Ang II) is independent of the systemic RAAS. There are some unique features in intrarenal RAAS compared to systemic RAAS. Unlike JG cells where Ang II inhibits renin release via the AngII type 1 (AT1) receptor by negative feedback, in the collecting duct Ang II stimulates renin expression via the AT1 receptor. Upregulated renin produced in the distal nephron may be able to support continued intrarenal Ang II formation leading to amplification or maintenance of the hypertensive state.The recently discovered angiotensin-converting enzyme-related carboxypeptidase 2 (ACE2)-Angiotensin-(1-7) Ang-(1-7)-Mas receptor axis has an opposing function to that of the ACE-Ang II-AT1 receptor axis.The ACE2 deficiency was associated with an increase in blood pressure, and ACE2 knockout mice have highlighted hypertensive response to Ang II infusion associated with exaggerated accumulation of Ang II in the kidney. Recently, several numbers of patients have been evaluated as the activators of ACE2-Ang-(1-7)-Mas receptor axis, which can be divided into two main classes: aimed to increase the activity of ACE2, and directed to stimulate the Ang-(1-7) receptor Mas. In order to investigate new targets for hypertension and kidney disease, further research on the function of the ACE-Ang-(1-7)-Mas receptor axis is required. ","PeriodicalId":35352,"journal":{"name":"Electrolyte and Blood Pressure","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5049/EBP.2013.11.2.41","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32173910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 61

Severe Hyponatremia Associated with the Use of Angiotensin II Receptor Blocker/thiazide Combinations. 严重低钠血症与血管紧张素受体阻滞剂/噻嗪类药物联合使用相关

Electrolyte and Blood Pressure Pub Date : 2013-12-01 Epub Date: 2013-12-31 DOI: 10.5049/EBP.2013.11.2.56

Da-Rae Kim, Joo-Hee Cho, Won-Seok Jang, Jin-Sug Kim, Kyung-Hwan Jeong, Tae-Won Lee, Chun-Gyoo Ihm

{"title":"Severe Hyponatremia Associated with the Use of Angiotensin II Receptor Blocker/thiazide Combinations.","authors":"Da-Rae Kim, Joo-Hee Cho, Won-Seok Jang, Jin-Sug Kim, Kyung-Hwan Jeong, Tae-Won Lee, Chun-Gyoo Ihm","doi":"10.5049/EBP.2013.11.2.56","DOIUrl":"https://doi.org/10.5049/EBP.2013.11.2.56","url":null,"abstract":"There are several widely used combinations of angiotensin II receptor blocker (ARB)/thiazide. The complimentary mechanism of action for such anti-hypertensive therapies is that, while ARB inhibits the vasoconstricting and aldosterone-secreting effects of angiotensin II, hydrochlorothiazide affects the renal tubular mechanisms of electrolyte reabsorption and increases excretion of sodium and chloride in the distal tubule, consequently promoting water excretion. In addition, hypokalemia, which may be triggered by a hydrochlorothiazide-induced increase in urinary potassium loss, is resisted by the use of ARB. Hence, the ARB/thiazide combination is safe in terms of potassium imbalance. For these reasons, fixed-dose ARB/thiazide combination anti-hypertensive drugs have been widely used for the treatment of hypertension. However, there have not been many studies done regarding cases where patients under such regimens showed severe hyponatremia, even when the amount of thiazide included was low. Here we report two cases in which severe hyponatremia occurred following treatment with the ARB/thiazide combinations. Upon discontinuation of the regimen, both patients showed recovery from hyponatremia. ","PeriodicalId":35352,"journal":{"name":"Electrolyte and Blood Pressure","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5049/EBP.2013.11.2.56","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32173913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Adrenergic genetic mechanisms in hypertension and hypertensive kidney disease. 高血压和高血压肾病的肾上腺素能遗传机制。

Electrolyte and Blood Pressure Pub Date : 2013-06-01 Epub Date: 2013-06-30 DOI: 10.5049/EBP.2013.11.1.24

Sun Woo Kang

{"title":"Adrenergic genetic mechanisms in hypertension and hypertensive kidney disease.","authors":"Sun Woo Kang","doi":"10.5049/EBP.2013.11.1.24","DOIUrl":"https://doi.org/10.5049/EBP.2013.11.1.24","url":null,"abstract":"Catecholamine secretory traits were significantly heritable, as were stress-induced blood pressure changes. Tyrosine hydroxylase (TH) is the rate-limiting enzyme in catecholamine biosynthesis. In the tyrosine hyroxylase promoter, significant associations were found for urinary catecholamine excretion and for blood pressure response to stress. TH promoter haplotype 2 (TGGG) showed pleiotropy, increasing both norepinephrine excretion and blood pressure during stress. In hypertension, 2 independent case-control studies (1,266 subjects with 53% women and 927 subjects with 24% women) replicated the effect of C-824T in the determination of blood pressure. Chromogranin A (CHGA) plays a fundamental role in the biogenesis of catecholamine secretory granules. Changes in the storage and release of CHGA in clinical and experimental hypertension prompted us to study whether genetic variation at the CHGA locus might contribute to alterations in autonomic function, and hence hypertension and its target organ consequences such as hypertensive kidney disease (nephrosclerosis). Systematic polymorphism discovery across the human CHGA locus revealed such regulatory regions as the proximal promoter and 3'-UTR. In chromaffin cell-transfected CHGA 3'-UTR and promoter/luciferase reporter plasmids, the functional consequences of the regulatory/non-coding allelic variants were documented. Variants in both the proximal promoter and the 3'-UTR displayed statistical associations with hypertension and hypertensive end stage renal disease. Therefore, I would like to review the common genetic variation in TH and CHGA as a cause of inter-individual variation in sympathetic activity, and ultimately blood pressure and hypertensive kidney disease. ","PeriodicalId":35352,"journal":{"name":"Electrolyte and Blood Pressure","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5049/EBP.2013.11.1.24","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31658307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Paranoid Adipsia-induced Severe Hypernatremia and Uremia treated with Hemodialysis. 血液透析治疗重度高钠血症和尿毒症。

Electrolyte and Blood Pressure Pub Date : 2013-06-01 Epub Date: 2013-06-30 DOI: 10.5049/EBP.2013.11.1.29

Jae-Hyun Choi, Hee Seung Lee, Sun Moon Kim, Hye-Young Kim, Soon Kil Kwon

引用次数: 5

The role of v2 receptor antagonists in the treatment of hyponatremia. v2受体拮抗剂在治疗低钠血症中的作用。

Electrolyte and Blood Pressure Pub Date : 2013-06-01 Epub Date: 2013-06-30 DOI: 10.5049/EBP.2013.11.1.1

Biff F Palmer

引用次数: 10