Dermatology Journal of Cosmetic and Laser Therapy最新文献

{"title":"New Protocol: EndoliftX Laser and Hyaluronic Ac+ Calcium Hydroxiapaptite as an Effective Approach for Facial Rejuvenation- Case Series of 7 Patients","authors":"","doi":"10.33140/djclt.02.03.05","DOIUrl":"https://doi.org/10.33140/djclt.02.03.05","url":null,"abstract":"Background: Excessive submental fat and tissue laxity can significantly impact an individual's aesthetic appearance, leading to cosmetic dissatisfaction and concerns about aging. Non-invasive and minimally invasive treatments have gained popularity as alternatives to surgical interventions. Laser lipolysis, such as EndoliftX®, has emerged as a promising approach for submental fat reduction, and hybrid fillers, like HArmonyCa, have shown potential for enhancing tissue laxity. Objective: This study aimed to evaluate the efficacy and long-term outcomes of a novel combined treatment protocol utilizing laser lipolysis and hybrid filler injection for submental fat reduction and tissue tightening. Methods and Materials: A single-center, prospective, quasi-experimental controlled study was conducted, enrolling seven patients aged between 49 and 67 years. The protocol EndoliftX®, involved a 1470nm diode laser (LASEmaR 1500® Eufoton® Trieste,Italy) treatment (Endolift) followed by hybrid filler (HArmonyCa) injection. Various assessments, including clinical examination, Glogau Scale scoring, and 3D imaging, were performed at baseline and follow-up visits. Results: The results demonstrated significant reductions in submental fat, improved cutaneous elasticity, and reduced wrinkle severity according to the Glogau Scale. Notably, these improvements were visible almost immediately post-procedure and continued to enhance over time, remaining prominent even after 12 months of observation. The treatment was associated with minimal discomfort and downtime. Conclusion: The study highlights the effectiveness and longevity of the combined treatment protocol, making it a valuable option for individuals seeking non-surgical solutions for submental fat reduction and tissue tightening. While further research with control groups is warranted, laser lipolysis with EndoliftX®, and hybrid filler injection with HArmonyCa offer a minimally invasive and well-tolerated approach to address submental concerns and achieve favorable aesthetic outcomes, particularly in patients looking to avoid more invasive techniques.","PeriodicalId":351393,"journal":{"name":"Dermatology Journal of Cosmetic and Laser Therapy","volume":"62 6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139238500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paradoxical Pustular Psoriasis Following Treatment of Chronic Plaque Psoriasis with Ustekinumab","authors":"Case Report, Ou Min, Xiaoling Yu, Yunling Yan, Lin Xiuqiu, Xiaohua Wang, Xiaohua Wang","doi":"10.33140/djclt.01.01.03","DOIUrl":"https://doi.org/10.33140/djclt.01.01.03","url":null,"abstract":"A 51-year-old female with red plaques and scales for 20 years, aggravated with pustules for more than 10 days.Physical examination: scattered red patches, silver-white scales, thin film, Auspitz sign (+) can be seen on the head and face.The trunk and limbs were scattered in large erythema and erythema, on which were dense pustules of the size of chestnut. The central color of local pustules was brown, presenting target-shaped lesions, and some pustules fused into pus lake.Vulvar mucosa scattered in pustules, erosion surface.Nail clipping thimble changes, deck thickening changes.Histopathology: Hyperkeratosis, fusion keratosis, thinning or disappearance of granular layer, epidermal psoriatic hyperplasia, munro and Kogoj microabscess, dermal papilloma, vascular dilatation, perivascular lymphocyte infiltration.Diagnosis: pustular psoriasis.","PeriodicalId":351393,"journal":{"name":"Dermatology Journal of Cosmetic and Laser Therapy","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127300109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Some Features of Self-Assessments by Doctors of Quality Own Life During the Coronavirus Pandemic","authors":"","doi":"10.33140/djclt.01.01.02","DOIUrl":"https://doi.org/10.33140/djclt.01.01.02","url":null,"abstract":"The term VUCA has recently appeared in the information field of the first decades of the 21st century. It quite clearly reflects the basic features of modern life: instability (Volatility) — due to the need to take into account many factors that change in the process of making certain decisions; uncertainty — the real impossibility of predicting the future and its main prospects; Complexity — lack of real understanding of the essence of many events; ambiguity — ambiguity and clear uncertainty in the interpretation of a considerable number of life situations. All this together could not help but affect the self-assessment of young doctors about their quality of life (QoL) during the COVID-19 pandemic. The purpose of the study: is to trace the dynamics of changes in the self-assessment of certain indicators of quality of life among young medical workers and students of the O.O.Bogomolets National medical university against the background of the negative impact of the infodemic and attempts to at least somehow \"relieve\" this chronic stressful situation by improving one's appearance with the help of cosmetics during the COVID-19 pandemic during 2020— 2021 Results and Discussion: Interpersonal contacts with students of the 4th year of the medical and dental faculties were due to the circumstances of their distance learning during the pandemic at the department of dermatology and venereology with a course of cosmetology of the O.O.Bogomolets National édictai university and were based on the results of their distance self-testing for the period from spring 2020 to December 2021. Such testing took place mainly on the initiative of the medical workers themselves, after they learned about the possibility of objectively assessing their psychological state and quality of life. An objective analysis of the dynamics of self-assessments of their own quality of life over the past two years in complex, rather unpredictable due to instability, ambiguity and certain uncertainty in the conditions of the pandemic indicates their rather successful psychosomatic adaptation to training and clinical work. Their averaged self-assessments of quality of life should be considered as a kind of positive standard when compared with the data of similar tests conducted among other segments of the population in the same period of time. Conclusions: An objective analysis of the dynamics of self-assessments by young doctors of their own quality of life over the past two years indicates their rather successful psychosomatic adaptation in the conditions of the infodemic and pandemic of 2020-2021. Their point values on the SF-36 scales should be considered as a kind of positive quantitative standard that reflects their generally optimistic psychosomatic adaptation during this difficult period of development of human civilization.","PeriodicalId":351393,"journal":{"name":"Dermatology Journal of Cosmetic and Laser Therapy","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114793591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How We Do It: Narrow Hole Extrusion Technique for Lipoma Removal","authors":"","doi":"10.33140/djclt.02.03.02","DOIUrl":"https://doi.org/10.33140/djclt.02.03.02","url":null,"abstract":"Subcutaneous lipomas are benign, slow-growing tumors of adipose tissue. The goal of removal is to achieve complete extirpation with optimal cosmesis. Given the inherent features of these subcutaneous lesions, complete extirpation can consistently be achieved through very small incisions, a technique known as narrow hole extrusion technique.","PeriodicalId":351393,"journal":{"name":"Dermatology Journal of Cosmetic and Laser Therapy","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127877973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effective Continuous Renal Replacement Therapy and Music Therapy for a Comatose Patient with Encephalopathy: A Case Report","authors":"Case Report, Amir Hossein, Mohammad Lotfi1, Taheri2, Arezou Hosseini3, Abdorrahim Absalan4, MSc. Mohammad Taheri","doi":"10.33140/djclt.02.03.01","DOIUrl":"https://doi.org/10.33140/djclt.02.03.01","url":null,"abstract":"A 35-year-old woman presented with a one-week history of Covid-19 symptoms. Despite negative results for COVID-19 and influenza virus, she suffered a tonic-clonic seizure lasting one minute and experienced a subsequent decrease in the level of consciousness to 7, which further decreased to 2+T/15 accompanied by low oxygen saturation. Despite various clinical and paraclinical evaluations, no definite cause for the patient's low LOC could be determined, and various therapies and medications failed to improve her condition. Given the septic phase, two rounds of continuous renal replacement therapy were conducted, in conjunction with music therapy and reminiscence featuring the voices of her loved ones. After 48 hours from the last round of CRRT, and following 50 days of hospitalization in the intensive care unit, her LOC improved to 8+T/15. We propose CRRT and music therapy and reminiscence as possible treatment approaches for patients with unexplained coma and unresponsiveness to therapies.","PeriodicalId":351393,"journal":{"name":"Dermatology Journal of Cosmetic and Laser Therapy","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132893643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ectodermal Dysplasia ‑ A Case Report from Nepal","authors":"Kamala Acharya, Sapana Karn, S. Marahatta","doi":"10.33140/djclt.02.02.02","DOIUrl":"https://doi.org/10.33140/djclt.02.02.02","url":null,"abstract":"Ectodermal dysplasia (ED) is a rare genetic disorder with abnormal development of two or more ectodermal derivatives. These include defects in skin, nails, hair, teeth and sweat glands. A multidisciplinary approach is required for management of such cases. A case of 9 years old boy with ED is reported here.","PeriodicalId":351393,"journal":{"name":"Dermatology Journal of Cosmetic and Laser Therapy","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121932977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of Demand for Health Care Services by Rural Households","authors":"Review Article, Ogundipe Michael, Adenekan Adesola","doi":"10.33140/djclt.02.02.01","DOIUrl":"https://doi.org/10.33140/djclt.02.02.01","url":null,"abstract":"The study looked into the factors that influence rural families in the Akinyele Local Government's need for health care services. Two hundred (200) questionnaires were employed to collect certain important and pertinent data. Regression analysis, percentages, and frequency distribution statistics are some of the techniques employed. This frequency and the percentage allow us to understand how the respondents feel about the queries posed and answers provided. The regression analysis was utilized to determine the variables' sign and size as well as their significance. The regression analysis shows that price of healthcare service, the cost of drug, educational qualification and the distance to health centres are statistically significant in determining the demand for health care services among the people in Akinyele local government area while income, age and gender are statistically insignificant. As price of healthcare services, cost of drugs and distance to health centres are significant at 5% level of significance, education qualification is significant at 10% level of significance.","PeriodicalId":351393,"journal":{"name":"Dermatology Journal of Cosmetic and Laser Therapy","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134362719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Features of Self Assessments of the Quality of one's Own Life During the Pandemic and the Beginning of Missile Attacks on the Civilian Infrastructure of Ukraine","authors":"Researc H Article, K. Kolyadenko, O. Fedorenko, O.O.Bogomolets","doi":"10.33140/djclt.02.01.01","DOIUrl":"https://doi.org/10.33140/djclt.02.01.01","url":null,"abstract":"Even before the beginning of the military attack of the Russian Federation on Ukraine, the term VUCA appeared in the national information field, which concentrates the basic features of the modern life-being of the society of the 21st century: volatility (Volatility) - due to the urgent need to take into account numerous changing factors; uncertainty (Uncertainty) the real impossibility of predicting the main perspectives; Complexity lack of real understanding of the essence of many events; ambiguity (Ambignity) clear uncertainty of interpretation of a considerable number of life situations. All these separate components of VUCA became even more \"sharpened\" after 24.02.2022 and could not help but affect the self-assessment of the quality of life (QoL) of somatically healthy young doctors under the simultaneous combined informational pressure of both the COVID-19 pandemic and the beginning of a full-scale war. 44.","PeriodicalId":351393,"journal":{"name":"Dermatology Journal of Cosmetic and Laser Therapy","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131850260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dermatology Journal of Cosmetic and Laser Therapy","authors":"","doi":"10.33140/djclt.01.01.08","DOIUrl":"https://doi.org/10.33140/djclt.01.01.08","url":null,"abstract":"Background: Cuproptosis is a recently discovered method of copper-induced cell death that serves an essential part in the progression and spread of stomach adenocarcinoma (STAD). Multiple studies have found that lncRNAs, or long non-coding RNAs, are strongly correlated with the outcome for STAD patients. However, the nature of the connection between cuproptosis and lncRNAs in STAD is still not completely understood. Our study set out to create a predictive hallmark of STAD based on lncRNAs associated with cuproptosis, with the hope that this would allow for more accurate prediction of STAD outcomes. Methods: We retrieved the transcriptional profile of STAD as well as clinical information from The Cancer Genome Atlas (TCGA). The cuproptosis-related genes (CRGs) were gathered through the highest level of original research and complemented with information from the available literature. We constructed a risk model using co-expression network analysis, Cox regression analysis, and least absolute shrinkage and selection operator (LASSO) analysis to identify lncRNAs associated with cuproptosis, and then validated its performance in a validation set. Survival study, progression-free survival analysis (PFS), receiver operating characteristic (ROC) curve analysis, Cox regression analysis, nomograms, clinicopathological characteristic correlation analysis, and principal components analysis were used to evaluate the signature's prognostic utility. Additionally, ssGSEA algorithms, KEGG, and GO were employed to assess biological functions. The tumor mutational burden (TMB) and tumor immune dysfunction and rejection (TIDE) scores were utilized in order to evaluate the effectiveness of the immunotherapy. Results: In order to construct predictive models, nine distinct lncRNAs (AC087521.1, AP003498.2, AC069234.5, LINC01094, AC019080.1, BX890604.1, AC005041.3, DPP4-DT, AL356489.2, AL139147.1) were identified. The Kaplan-Meier and ROC curves, which were applied to both the training and testing sets of the TCGA, provided evidence that the signature contained a sufficient amount of predictive potential. The signature was shown to contain risk indicators that were independent of the other clinical variables, as demonstrated by the findings of a Cox regression and a stratified survival analysis. The ssGSEA study provided additional evidence that predictive variables were highly connected with the immunological condition of STAD patients. Surprisingly, the combination of high risk and high TMB reduced survival time for patients. A worse prognosis for the immune checkpoint blockade response was also suggested by the fact that patients in the high-risk group had higher TIDE scores. Conclusion: The potential clinical uses of the identified risk profiles for the 10 cuproptosis-related lncRNAs include the assessment of the prognosis and molecular profile of STAD patients and the creation of more targeted therapy strategies.","PeriodicalId":351393,"journal":{"name":"Dermatology Journal of Cosmetic and Laser Therapy","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129322485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nairobi fly dermatitis cases in Ade charake village in Bodit town Administration, Wolaita Zone, SNNPR, Ethiopia, 2018","authors":"Researc H Article, Mesay Gunta1, Mesay Hailu3, David Sugerman4, Haile Bekele5, Behailu Shibesh6, Mesay Gunta","doi":"10.33140/djclt.01.01.06","DOIUrl":"https://doi.org/10.33140/djclt.01.01.06","url":null,"abstract":"Background: Nairobi fly dermatitis is unusual form of contact dermatitis caused by pederine, ahemolymph fluid released when the insects are crushed against the skin. Patients often present with a sudden onset burning sensation and cutaneous pain. The insects are belonging to the genus Paederus. These insects are found worldwide, although the concentration is higher in tropical and subtropical areas. In Ethiopia, more particularly in Wolaita, Nairobi fly dermatitis is uncommon previously. Hence, we aimed to describe the clinical characteristics and identify risk factors prone to the disease. Methods: We conducted unmatched case-control study (ratio 1:2) with 45 cases and 90 controls from April 5 to 14, 2018 in Ade charake Village, Southern Ethiopia. Cases were patients who had a history of linear dermatitis, kissing/mirror image/ lesions, multiple vesiculo-pustular lesion, extensive pustules, blistering and papulo-pustular lesions over face, neck, arms, shoulders, axillaries region, lower limbs, chest, upper limbs or any other area of the body in Ade Charake Village in the study period. Controls were asymptomatic individuals selected randomly from the households or neighbors during the outbreak period. The investigators initially developed a clinical-epidemiological questionnaire to obtain data from cases as well as controls. Basic descriptive summary including attack rate, in addition to bivariate and multivariable logistic regression was computed. The odds ratio was computed at 95% CI with a P-value <=0.05 to ascertain the association. Results: Among 45 cases, 60 %( 27/45) were females. The commonly affected age groups were between 8-15 years 31% (14/45). The frequently appearing clinical manifestation was Erythmato-vesicular lesions 40% (18/45) and most patients 71% (32/45) presented with a complain of burning sensation followed by pruritus 62% (28/45).We found that use of light during sleep (AOR=8.5,95% CI, 1.033-64.8), disposing wastes near vicinity(AOR=5.44, 95% CI 2.094,14.1250) and proximity of dense vegetations or fruit in the vicinity (AOR=7,95% CI, 1.143-43.78) were risk factors to develop Nairobi fly dermatitis. Conclusion: We found that Nairobi fly dermatitis predominantly affects females while sleeping with light on and disposing of wastes near vicinity. The presence vegetation’s and/or fruits in the neighborhood found to be the risk factors for Nairobi fly dermatitis.","PeriodicalId":351393,"journal":{"name":"Dermatology Journal of Cosmetic and Laser Therapy","volume":"191 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115617658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}