{"title":"Smokeless Tobacco A Deadly Addiction","authors":"Wajiha Zia, M. Kashif","doi":"10.46663/ajsmu.v8i2.82","DOIUrl":"https://doi.org/10.46663/ajsmu.v8i2.82","url":null,"abstract":"Although there are several tobacco products available, smokeless tobacco is the most commonly used1. SLT is being used more frequently, which can be attributable to its low price and straightforward accessibility in every other store around. SLTs are oral tobacco products that are non-combustible. It can also be breathed through the nose; however, it is typically inserted under the tongue or in the space between the cheeks and gums. SLTs come in a variety of forms, including as dipping tobacco, snuff, betel-quid, mawa, naswar, and gutka.","PeriodicalId":350655,"journal":{"name":"ANNALS of JINNAH SINDH MEDICAL UNIVERSITY","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115703937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Erum Afaq, Muhammed Nisar, Muhammad Irfan, Syed Hafeez-ul- Hassan, Talha Ahmed
{"title":"The Correlation of Peak Expiratory Flow Rate and Hand Dynamometry in Chronic Obstructive Pulmonary Disease Patients A Case Control study","authors":"Erum Afaq, Muhammed Nisar, Muhammad Irfan, Syed Hafeez-ul- Hassan, Talha Ahmed","doi":"10.46663/ajsmu.v8i2.69-73","DOIUrl":"https://doi.org/10.46663/ajsmu.v8i2.69-73","url":null,"abstract":"Objectives: To determine the correlation of peak expiratory flow rate and hand dynamometry in patients with chronic obstructive pulmonary disease and to find out the differences between hand grip in cases and control group Methodology: This study was carried out in the Department of Physiology and Department of Chest Medicine, Liaquat National Hospital and Medical College between July 1st 2019 and June 30th 2020 after the approval of the research and ethical committee of the same hospital. We used purposive sampling technique. Total 100 consenting individuals were recruited that were equally divided into control group and chronic obstructive pulmonary disease group. Anthropometric measurements alongwith peak expiratory flow rate and hand dynamometry values were measured. Results: We found significant difference in hand grip strength and peak expiratory flow rate between the case and control groups, chronic obstructive pulmonary disease patients have decreased peak expiratory flow rate and handgrip strength. Weak correlation exists between peak expiratory flow rate and hand grip strength with significant p value. No relationship was found between waist hip ratio and hand grip. Also, body mass index showed a weak negative but statistically significant correlation with hand grip strength. Conclusion: In chronic obstructive pulmonary disease patients, hand grip strength is decreased and determining hand grip strength may ensures quick assessment of quality of life.","PeriodicalId":350655,"journal":{"name":"ANNALS of JINNAH SINDH MEDICAL UNIVERSITY","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129827907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Kumari, A. Lari, A. Shahid, A. Farooqui, K. Abbas, F. Bashir
{"title":"Awareness of HPV Infection and its Relationship to Cervical Cancer in Medical Students of Karachi, Pakistan A Cross Sectional Study","authors":"K. Kumari, A. Lari, A. Shahid, A. Farooqui, K. Abbas, F. Bashir","doi":"10.46663/ajsmu.v8i2.74-79","DOIUrl":"https://doi.org/10.46663/ajsmu.v8i2.74-79","url":null,"abstract":"Objective: To assess the level of awareness among medical students about HPV, its vaccines and its relation to cervical cancer Methodology: This is a cross-sectional, multicenter study conducted at Creek General Hospital, Karachi from March 2020 to November 2021 after IRB approval from United Medical and Dental College. Data was collected from undergraduate MBBS students via an online questionnaire. Results: Total participants in the study were 219. Age range was between 18 and 26 years. A majority (82%) of medical students were aware of the causal relationship between HPV and cervical carcinoma. Only 53% of students had the knowledge for the need for regular pap smear. Students confessed about lack of knowledge regarding HPV and its preventive measures with 82% of students admitting to having gaps in their knowledge. Conclusion: The study brings us to the conclusion that the current medical curriculum is not fortified and hence the medical students are unaware about the diagnostic and preventive strategies of cervical cancer which is a good gap in their clinical career.","PeriodicalId":350655,"journal":{"name":"ANNALS of JINNAH SINDH MEDICAL UNIVERSITY","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133924517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stem Cell Role in Regenerative Dental Medicine","authors":"Robia Ghafoor","doi":"10.46663/ajsmu.v8i2.45-46","DOIUrl":"https://doi.org/10.46663/ajsmu.v8i2.45-46","url":null,"abstract":"Regeneration therapies have widely permeated advanced research that aims to reproduce and repair a lost or damaged organ or tissue in order to restore the function and architecture as close to its original state as possible. Tissue engineering refers to the process of regeneration using techniques such as scaffold based cell cultures, stem cell therapy, and biomolecular signaling.","PeriodicalId":350655,"journal":{"name":"ANNALS of JINNAH SINDH MEDICAL UNIVERSITY","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116100537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contraceptive Usage and Social Barriers During The Covid-19 Pandemic","authors":"R. Mustafa, Sagheera Anjum Munaver, Anjum Munaver","doi":"10.46663/ajsmu.v8i2.64-68","DOIUrl":"https://doi.org/10.46663/ajsmu.v8i2.64-68","url":null,"abstract":"Objective: To determine the frequency of contraceptive usage, the social barriers affecting their use, and the frequency of unplanned pregnancies during the COVID-19 pandemic Methodology: This is a prospective cross-sectional study carried out at the Department of Obstetrics and Gynaecology, Fazaia Ruth Pfau Medical College & PAF Hospitals from July 2020 to September 2020. All women of reproductive age attending the outpatient department were consecutively included. A pre-structured questionnaire was used for the purpose of collection of data. We obtained information regarding the use of contraception before and during the COVID-19 pandemic and the contraception methods used by these women. Furthermore, reasons for discontinuing contraception amongst those women who were using it earlier. The occurrence of pregnancy during pandemic was also noted. Results: Of the 350 women, 306 (87.4%) women practiced contraception before and 288 (82.3%) practiced it during the lockdown. Of 306 women practicing contraception before the lockdown, 265 (86.6%) continued practicing during the lockdown as well. Condom 145 (50.3%) and withdrawal method 116 (40.3%) were the most used methods amongst the 288 women practicing contraception during the lockdown. The noticeable increase in the number of those using withdrawal method was due to the lack of consultation following the fear of getting COVID (17 women, 41.5%) and no access to the clinic (14 women, 34.1%). These were the most common reasons for not using contraception, amongst the 41 women practicing contraception before the pandemic. Pregnancies were reported by 93 (26.6%) women out of whom 75 (80.6%) reported these to have been unplanned. Conclusion: The COVID pandemic has largely affected the utilization of contraceptives among women who were already practicing different contraceptive methods. Moreover, unplanned pregnancies are increasingly reported by women.","PeriodicalId":350655,"journal":{"name":"ANNALS of JINNAH SINDH MEDICAL UNIVERSITY","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116795214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of Dynamization on Delayed Union of Tibial Shaft Fractures After Reamed Intramedullary Interlocked Nailing","authors":"Pervez Ali, Mian Sajjad, M. Hussain, Fahad Jatoi, Ejaz Matlo, Riaz Khoso","doi":"10.46663/ajsmu.v8i2.59-63","DOIUrl":"https://doi.org/10.46663/ajsmu.v8i2.59-63","url":null,"abstract":"Objective: To determine the efficacy of dynamization in delayed union of tibia diaphyseal fractures Methodology: A descriptive cross sectional study was done at the Department of Orthopaedic Surgery, Jinnah Postgraduate Medical Center, Karachi, Pakistan, from July 2020 to April 2021. A total of 97 consenting patients who suffered from delayed union following intramedullary interlocking nailing were included in the study. Dynamization involved removal of proximal or distal locking screws in statically locked intramedullary nail. Patients were followed up for six months to check for delayed bone union. All the collected data were entered into a pro forma and used electronically for research purpose. Results: Over all union was achieved in 72 (74.2%) cases after dynamization. The mean age of our study population was 39.42+13.79 years. Advanced age, smoking, fresh or old fracture, the time of initial intramedullary nailing, and diabetes were associated with decreased efficacy of dynamization, with p-value <0.001, 0.033, 0.007, and <0.001 respectively. While no significant association was found between gender, BMI, hypertension, and union (p-value >0.05). Conclusion: The findings of this study support the idea that dynamization can be an effective method to promote healing in tibia diaphyseal fractures for delayed union. More randomized comparative clinical trials are necessary to evaluate the effectiveness of dynamization.","PeriodicalId":350655,"journal":{"name":"ANNALS of JINNAH SINDH MEDICAL UNIVERSITY","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125003329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saima Akhter, Nausheen Saifullah, B. Hassan, S. Jafri, Naseem Ahmed
{"title":"COVID-19 Inside Out In-hospital Outcomes at a Public Sector Tertiary Care Hospital in Karachi","authors":"Saima Akhter, Nausheen Saifullah, B. Hassan, S. Jafri, Naseem Ahmed","doi":"10.46663/ajsmu.v8i2.54-58","DOIUrl":"https://doi.org/10.46663/ajsmu.v8i2.54-58","url":null,"abstract":"Objective: To present in-hospital COVID-19 mortality and the associated factors at a public sector tertiary care hospital in Karachi Methodology: The current prospective, observational study was conducted at Jinnah Postgraduate Medical Center, Karachi, Pakistan from June 1 to August 30, 2021 with the approval of the hospital ethics committee. Data was collected prospectively from patients’ medical record files. COVID-19 infection positive cases were diagnosed according to the guidelines of the WHO on laboratory investigation of real time polymerase chain reaction tests on a nasopharyngeal or oropharyngeal swab. Result: Total 143 patients were enrolled in the study with median (IQR) age of 58 (48–69). The majority of the patients were males (n=96, 67.13%) and had moderate to severe disease (n=128, 89.51%). During their hospital stay, patients developed the following complications; pneumonia (n=99, 69.23%), ARDS (n=19, 13.28%), sepsis (n=11, 7.69%), septic shock (n=5, 3.49%) and pedal edema (n=2, 1.39%). As many as 104 (72.72%), 69 (48.25%), and 42(29.37%) patients required pharmatherapy, non-invasive ventilation, and mechanical ventilation respectively. While 54 (37.76%) patients died during their hospital stay. On multivariable model, pneumonia, use of non-invasive ventilation, and mechanical ventilation, were identified as independent predictors of mortality. Conclusion: Most of the patients in our study had moderate to severe disease. Therefore, the study indicates that timely presentation to the hospital is of great importance to avoid adverse events which are significantly associated with mortality.","PeriodicalId":350655,"journal":{"name":"ANNALS of JINNAH SINDH MEDICAL UNIVERSITY","volume":"228 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123062168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical Repair of Nasal Vestibular Stenosis A Case Report","authors":"Beenish Nisar Ahmed, Muhammad Yasir Khan","doi":"10.46663/ajsmu.v8i2.80-81","DOIUrl":"https://doi.org/10.46663/ajsmu.v8i2.80-81","url":null,"abstract":"Vestibular stenosis is an uncommon but debilitating cause of nasal obstruction leading to serious impairment of airway. It is caused by granulation and fibrosis of vestibular lining and there is circumferential scar retraction in the inlet of nasal cavities. Stenosis may be congenital or acquired. Causes of acquired stenosis include burns, trauma, infections, and iatrogenic insult to the lining of vestibule. Surgical correction is usually done by excision of fibrous tissue. A number of studies have been reported on surgical correction but not a single technique is widely accepted due to different diseases and different levels of deformities. Here we are suggesting a technique in which flaps have been raised and scar fibrous tissue is removed. This technique gives a good outcome and satisfactory result in a patient with post traumatic unilateral stenosis.","PeriodicalId":350655,"journal":{"name":"ANNALS of JINNAH SINDH MEDICAL UNIVERSITY","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117019724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vikash Kumar, Shahzaib Rehman, N. Jaffar, Nimrah Akram, K. Abbas, Moiz Ahmed
{"title":"Knowledge of Diabetes Mellitus among Undergraduate Clinical Students of Sindh Medical College","authors":"Vikash Kumar, Shahzaib Rehman, N. Jaffar, Nimrah Akram, K. Abbas, Moiz Ahmed","doi":"10.46663/ajsmu.v8i2.47-53","DOIUrl":"https://doi.org/10.46663/ajsmu.v8i2.47-53","url":null,"abstract":"Objective: To determine the knowledge of undergraduate students of Sindh Medical College regarding Diabetes Mellitus (DM) Methodology: This cross sectional study was conducted at Sindh Medical College, Jinnah Sindh Medical University (SMC-JSMU). The participants were students of 3rd year, 4th year and 5th year M.B.B.S. The sample size was calculated to be 282, using open EPI software. The data was collected through a scientifically designed questionnaire which included questions about the over all knowledge, risk factors, complications, diagnosis, treatment, methods of prevention, and WHO criteria of Diabetes Mellitus. SPSS version 22.0 was used for data analysis. Results: About 275 (98%) students had knowledge of the site of insulin production and 255 (90%) knew exactly how insulin produces its effects. Regarding the clinical presentation of DM, 262 (93%) of them agreed that hunger, thirst, and urination present as the major symptoms of this disease (p=0.005). Family history was considered as the prime risk factor by 93 (98%), 83 (95%) and 86 (86%) of final year, fourth, and third year students respectively (p=0.003). Furthermore, 254 (90%) selected retinopathy (p=0.00), 239 (85%) preferred nephropathy (p=0.003) and 224 (79%) considered neuropathy (p=0.024) as the most significant complication of DM. Moreover, the recall of the WHO diagnostic criteria for DM was comparatively lower in final year students (p=0.003). Conclusion: The over all knowledge of undergraduate medical students of Sindh Medical College was found to be satisfactory. Most of the students considered medical education as an adequate source of knowledge in this regard. However, capability of diagnosing DM was found to be comparatively low among final year M.B.B.S. students.","PeriodicalId":350655,"journal":{"name":"ANNALS of JINNAH SINDH MEDICAL UNIVERSITY","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126917898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Khalid, Komal yasmeen, Aimen shouket, Saira Jahan
{"title":"Gender-Based Frequency and Associated Disability of Rheumatoid Arthritis: A Cross-Sectional Study","authors":"R. Khalid, Komal yasmeen, Aimen shouket, Saira Jahan","doi":"10.46663/ajsmu.v8i1.26-29","DOIUrl":"https://doi.org/10.46663/ajsmu.v8i1.26-29","url":null,"abstract":"Objective: To determine the frequency and associated disability of rheumatoid arthritis in male and female patients Methodology: This was a cross sectional survey conducted at the National Institute of Rehabilitation Science, Pakistan Institute of Medical Science and Pakistan Railways Hospital for one year from February 2019 to February 2020. Study includes diagnosed cases of both genders with ages between 30 to 60 years and fulfilling the 1987 American College of Rheumatology (ACR) criteria. Patients with disabilities due to other reasons were excluded. Sample size of the study was calculated to be 143 using Epi-tool. Sampling technique was non-probability purposive sampling technique. For this study WHODAS-2.0 screening tool was used. Results: Out of 143 patients, 52 (36.4%) were males and 91(63.6%) were females. The mean age of both males and females was 43.41 ± 8.605 SD. We found that 18 (34.6%) male patients presented with mild disability. While in females, 54 (59.3%), 32 (35.16%), 5 (5.49%), and 0 (0%) patients out of 91, reported with mild, moderate, severe, and extreme disabilities respectively. Conclusion: RA is more prevalent in females than in males with the majority of the patients reporting mild disability and more female patients disabled than men.","PeriodicalId":350655,"journal":{"name":"ANNALS of JINNAH SINDH MEDICAL UNIVERSITY","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126272942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}