Open Access Journal of Reproductive System and Sexual Disorders最新文献

{"title":"Is Online Transgender Healthcare the Future? An Opinion","authors":"M. A. Naafs","doi":"10.32474/oajrsd.2018.01.000116","DOIUrl":"https://doi.org/10.32474/oajrsd.2018.01.000116","url":null,"abstract":"","PeriodicalId":350031,"journal":{"name":"Open Access Journal of Reproductive System and Sexual Disorders","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122031356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep and Menopause: Review","authors":"Starvaggi Agustina","doi":"10.32474/oajrsd.2018.01.000115","DOIUrl":"https://doi.org/10.32474/oajrsd.2018.01.000115","url":null,"abstract":"Sleep consists of REM and non-REM (rapid eye movement) periods that happen cyclically. Each one lasts between 90 to 120 minutes, and in one night there are approximately 4 to 6 cycles. During the first half of the night, non-REM cycles predominate, which are related to physical and mental restitution. On the contrary, in the second half of the night, REM cycles predominate, which participate in mental and emotional functions, including memory [1].","PeriodicalId":350031,"journal":{"name":"Open Access Journal of Reproductive System and Sexual Disorders","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130075821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges in the Treatment of Vasomotor Symptoms: Update in Non-Hormonal Strategies","authors":"Belardo María Alejandra, P. Susana, C. Malena, Starvaggi Agustina, Gelin Marina","doi":"10.32474/OAJRSD.2018.01.000113","DOIUrl":"https://doi.org/10.32474/OAJRSD.2018.01.000113","url":null,"abstract":"Perimenopause and menopause per se significantly impacts on women quality of life (QoL), especially due to vasomotor symptoms (VMS); their duration is uncertain, and often long. Although menopause hormone therapy (MHT) is the most effective treatment for climacteric symptoms as a whole, its use is contraindicated in some cases. Therefore, it is mandatory that different treatment approaches be offered to women for whom hormone therapy is contraindicated. As for treatment selection, there are a wide range of nonhormonal options, both pharmacological and nonpharmacological. These options include alternative or natural therapies (isoflavones and Cimicifuga Racemosa), lifestyle modifications and complementary therapies. Regarding pharmacological strategies the literature review shows that serotonin-norepinephrine reuptake inhibitors (SNRIs), selective serotonin reuptake inhibitors (SSRIs), antihypertensives and anticonvulsants, decrease the intensity and frequency of VMS, proving a clinically significant improvement.","PeriodicalId":350031,"journal":{"name":"Open Access Journal of Reproductive System and Sexual Disorders","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127467217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Pregnant Ladies Lifestyle on Pregnancy; Clinical Study in a Single Saudi Center","authors":"Muhammad Alsaddique, A. Chamsi","doi":"10.32474/OAJRSD.2018.01.000112","DOIUrl":"https://doi.org/10.32474/OAJRSD.2018.01.000112","url":null,"abstract":"Background: Complications in pregnancy are common and threatened miscarriage is occurring in approximately 20% of all pregnancies. The present study was conducted to determine various lifestyle factors leading to threatened abortion. Materials & Methods: This study was conducted in the department of Gynecology and Obstectrics which included 118 women. General information such as age, marital status, gestational age (weeks), educational level; housing, number of children, prepregnancy BMI (kg/m2), regularity of menstrual cycles; presence of nausea, history of miscarriage, history of benign gynaecological conditions; smoking status, caffeine intake, mobile phone use (in hours per day), computer use (hrs/day), history of depression or schizophrenia, extent of bleeding was recorded. Results: In our study, women with <34 years were 101 and >34 years were 17. Women had either high school education (100) and intermediate school (18), number of children were 0 in 98 women, 1 in 14 women and 2 in 6 women. The difference was significant (P<0.05). Patients with BMI<25 were 84 in number whereas with >25 were 34. Women with regular menstrual cycles were 102 whereas 16 had irregular cycle. The difference was significant (P<0.01). 78 had nausea while 40 had not. 18 gave positive history of previous miscarriage while 100 did not. 102 patients gave positive history of termination of pregnancy and 108 had gynecological diseases, 112 had given history of smoking in pregnancy, 30 had 1 or more household having history of smoking, 82 had positive history of caffeine intake, 78 had history of mobile use more than 4 hours, 58 had history of computer use more than 4 hours, 18 had history of depression, 44 had high stress score, 96 gave history of spotting bleeding during pregnancy, 8 had threatened abortion. The difference was significant (P<0.05). Conclusion: Lifestyle plays an important role the pregnancy. There is alteration in hormone level in pregnancy leading to miscarriage. Careful following of routine lifestyle prevent further complications in pregnancy.","PeriodicalId":350031,"journal":{"name":"Open Access Journal of Reproductive System and Sexual Disorders","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117276493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast Cancer Awareness","authors":"A. Bayramova, G. Krikun","doi":"10.32474/OAJRSD.2018.01.000111","DOIUrl":"https://doi.org/10.32474/OAJRSD.2018.01.000111","url":null,"abstract":"As an Ob & Gyn, member of National Breast Cancer Foundation and a woman I find it very important to raise awareness about the importance of early detection of Breast Cancer. Make a difference! Spread the word about mammograms and encourage communities, organizations, your friends and family members to get involved! Your help matters. Breast cancer is the most common type of tumors among the female population of the United States. One in eight women will be diagnosed with breast cancer in their lifetime.","PeriodicalId":350031,"journal":{"name":"Open Access Journal of Reproductive System and Sexual Disorders","volume":"85 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133336919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep Disorders in Perimenopausal Women and Metabolic Syndrome, is that True?","authors":"P. Susana, Belardo María Alejandra, C. Malena, De Nardo Bárbara, Starvaggi Agustina","doi":"10.32474/oajrsd.2018.01.000109","DOIUrl":"https://doi.org/10.32474/oajrsd.2018.01.000109","url":null,"abstract":"Sleep disorders (SD) are a common complaint in women going through menopause transition. It is well known that there is a close relationship between SD and one of the main menopausal symptoms: vasomotor symptoms (VMS). To acknowledge this association is essential when investigating menopausal transition and SD. The Study of Women’s Health across the Nation (SWAN), shows that the prevalence of sleep disturbance increases with age. The prevalence in perimenopausal and postmenopausal women varies from 39% to 47% and 35% to 60% respectively. Although both menopausal transition and aging increase sleep disturbances, etiology in menopausal women is probably multifactorial. A decline in the levels of reproductive hormones and melatonin, and the complex interaction among these hormones can significantly contribute to sleep problems, poor concentration, fatigue and decreased quality of life. On the one hand menopause nearly adversely affects all components of metabolic syndrome (MS) and on the other hand the cumulative long-term effects of deprived sleep have been associated with many cardio metabolic consequences including hypertension, obesity, and impaired glucose metabolism. Management strategies should be taken into account to help women ameliorate their night sleep, in order to prevent future complications and to improve their quality of life (QoL).","PeriodicalId":350031,"journal":{"name":"Open Access Journal of Reproductive System and Sexual Disorders","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122332734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of the Chemokine CXCL12 and its Receptors CXCR4 and CXCR7 in Human and Nonhuman Primate Uterine Leiomyomas","authors":"C. Booth, G. Krikun","doi":"10.32474/OAJRSD.2018.01.000108","DOIUrl":"https://doi.org/10.32474/OAJRSD.2018.01.000108","url":null,"abstract":"Uterine leiomyomas (also known as fibroids) are associated with several symptoms, including abnormal uterine bleeding, pressure-related symptoms, and recurrent pregnancy loss. These tumors affect up to 80% of fertile women between the ages of 30 and 50 years. However, there are currently no proven medical therapies for the long-term treatment of leiomyomas, and surgical treatment comes at a significant physical, psychological, and heath care costs. It is estimated the health system sustains annual costs of 22 billion dollars. CXCL12 (formerly known as stromal derived factor (SDF-1)) acts via its receptors CXCR4 and CXCR7 and is a potent chemokine found to be accessibly expressed in inflammatory diseases. Leiomyomas represent an inflammatory milieu; thus, we posit that the CXCL12/CXCR4/CXCR7 axis is involved in the progression of leiomyomas. This study is a prerequisite for nonhormonal and non-surgical treatment of leiomyomas. When comparing the expression of these molecules in leiomyomas vs. normal myometrium we noted the expression of this axis is elevated in humans and nonhuman primates. The similarities among human and nonhuman primates displayed extensive similarities. While CXCR4 stained both nuclei and cytoplasm in leiomyomas, CXCL12 and CXCR7 were confined to the cell membrane and cytoplasm.","PeriodicalId":350031,"journal":{"name":"Open Access Journal of Reproductive System and Sexual Disorders","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128933568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonmosaic Klinefelter Syndrome Successful Conception after TESE/ICSI: A case report","authors":"SayedElAkhras, K. Elsaeed, M. Halawa, M. Elsemary, AlyElakhras, Gajek Adam, V. Tanos","doi":"10.32474/OAJRSD.2018.01.000107","DOIUrl":"https://doi.org/10.32474/OAJRSD.2018.01.000107","url":null,"abstract":"Klinefelter syndrome patients are mostly clinically azoospermic, and before the era of TESE, were unable to father genetically their own offspring. Nonmosaic Klinefelter [NMK] patients have chances of fatherhood once sperm is harvested from the epididymal seminiferous tubules and further injected in the ovarian cytoplasm. We report a case of 36y old NMK patient, treated for 3 months with supportive and hormonal medication achieving a pregnancy after TESE/ICSI. This is the first published case of successful conception in a couple with a nonmosaic Klinefelter father in Egypt using TESE/ICSI. Review of the literature for any advantages of mTESE over TESE and conception demonstrated higher pregnancy rates by TESE although the sperm retrieval rate was similar in both techniques. Conclusion: Nonmosaic Klinefelter patients should no longer be considered sterile.","PeriodicalId":350031,"journal":{"name":"Open Access Journal of Reproductive System and Sexual Disorders","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125227775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Study of Magnesium sulphate vs Diazepam in Eclampsia","authors":"Tariq Khan","doi":"10.32474/OAJRSD.2018.02.000129","DOIUrl":"https://doi.org/10.32474/OAJRSD.2018.02.000129","url":null,"abstract":"Eclampsia is a life threatening condition with highest mortality and morbidity characterized by uncontrolled hypertension un-consciousness fits albumin urea in the setting the of Pre Eclampsia. \u0000 \u0000Study: An extensive elaborative study carried out from 2005 to 2009, to study the therapeutic and prophylactic role of Magnesium Sulphate and Diazepam in Eclampsia. \u0000 \u0000Study Period: Four Years 2005 to 2009. \u0000 \u0000Objective: To study MgSo4 Vs Diazepam reducing MMR, NMR in Eclampsia. \u0000 \u0000Study Design: This was a comparative study. Total 500 patients of fulminent pre- Eclampsia/Eclampsia were studied included booked / un-booked patients attending Lady Willingdon Hospital were admitted evaluated assessed and put on MgSo4 Vs Diazepam divided in two groups. The results were compared which showed of MgSo4 as superior in efficacy of compared to Diazepam in improving overall mortality morbidity in Eclampsia. \u0000 \u0000Material and Methods: Total 500 patients of Eclampsia admitted and studied in Unit – 2 Lady Willingdon Teaching Hospital of King Edward Medical University Lahore managed in ICU according to a specially design proforma, protocol and were given MgSo4 and Diazepam for control of fits, Hydralazine, Labetalol and Isoket infusions for lowering – blood pressure (MgSO4) A+B. (Diazepam) with multi disciplinary involvement divided in two groups compared and followed up. \u0000 \u0000Results: In Group-A there were 20 mothers and in Group-B 40 mothers died. It was observed that maternal mortality. Was significantly higher in Group-B women as compared to that of Group-A. i.e. (p-value=0.005) In Group-A there were 20 mothers and in Group-B 40 mothers died. It was observed that maternal mortality was significantly higher in Group-B women as compared to that of Group-A. i.e. (p-value=0.005) \u0000 \u0000Conclusion: The comparative study and of role of MgSO4 Vs Diazepam in reducing Mortality, morbidity in maternities, neoneties, efficacy showed the superiorness of Magnesium Sulphate as compared to Diazepam without any doubt.","PeriodicalId":350031,"journal":{"name":"Open Access Journal of Reproductive System and Sexual Disorders","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134175155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}