Optical Elastography and Tissue Biomechanics VI最新文献

Optical Elastography and Tissue Biomechanics VI Pub Date : 2019-04-19 DOI: 10.1117/12.2523407

引用次数: 1

A speckle interferometric technique for the evaluation of corneal biomechanics under physiological pressure variations (Conference Presentation) 斑点干涉技术在生理压力变化下评估角膜生物力学(会议报告)

Optical Elastography and Tissue Biomechanics VI Pub Date : 2019-03-13 DOI: 10.1117/12.2507660

A. Wilson, J. Marshall

引用次数: 3

High frequency traveling wave elastography of the cornea and sclera using a vibrating piezoelectric probe (Conference Presentation) 用振动压电探针进行角膜和巩膜的高频行波弹性成像(会议报告)

Optical Elastography and Tissue Biomechanics VI Pub Date : 2019-03-13 DOI: 10.1117/12.2508760

Antoine Ramier, S. Yun, Behrouz Tavakol

引用次数: 1

SS-OCT based ocular biometry and rheological mechanical model for comprehensive analysis of the eye reaction to air-puff stimulus (Conference Presentation) 基于SS-OCT的眼部生物测量和流变力学模型用于眼部对空气刺激反应的综合分析(会议报告)

Optical Elastography and Tissue Biomechanics VI Pub Date : 2019-03-13 DOI: 10.1117/12.2507832

A. Villar, M. Jannesari, M. Kadkhodaei, P. Mosaddegh, S. Grulkowski, B. Kaluzny, M. Wojtkowski, H. Kasprzak, I. Grulkowski

{"title":"SS-OCT based ocular biometry and rheological mechanical model for comprehensive analysis of the eye reaction to air-puff stimulus\u0000 (Conference Presentation)","authors":"A. Villar, M. Jannesari, M. Kadkhodaei, P. Mosaddegh, S. Grulkowski, B. Kaluzny, M. Wojtkowski, H. Kasprzak, I. Grulkowski","doi":"10.1117/12.2507832","DOIUrl":"https://doi.org/10.1117/12.2507832","url":null,"abstract":"The aim of this study was to develop a comprehensive biomechanical model to predict biomechanical properties of all ocular tissues and to compare the simulations with air-puff swept-source OCT data.\u0000We developed a novel rheological model of the whole eye. The cornea and the crystalline lens were modelled as a combination of spring and dashpot(s) to describe their viscoelastic properties. In addition, a mass element was included to model lenticular wobbling after air pulse. Finally, the eye retraction (depending on the fatty and muscle tissues behind the eye globe) was modeled by a parallel combination of a spring and dashpot elements, and a mass component described the weight of the eye.\u0000We measured deformation profiles of ocular components of the human eyes in-vivo using long-range SS-OCT instrument integrated with air-puff stimulation, which enables to visualize the dynamics of eye through its entire length and to measure the intraocular distances (SS-OCT ocular biometer). The deformations calculated from the model were fitted to the measured profiles data using Levenberg-Marquardt method. The rheological model allowed for predicting the displacements of the cornea and the crystalline lens (1.25mm and 0.115mm, respectively), the eye retraction (0.28mm) and the axial wobbling of the lens within 40ms. The developed model outcomes match well to experimental data of corneal and lenticular hysteresis curves identifying viscoelastic properties of the ocular tissues\u0000\u0000In conclusion, the proposed rheological model correctly predicts the effects observed with air-puff SS-OCT ocular biometer and it can be used in future modelling of the whole eye biomechanics.","PeriodicalId":348521,"journal":{"name":"Optical Elastography and Tissue Biomechanics VI","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131074489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Non-contact quantification of tissue biomechanics during embryo development with Brillouin microscopy and optical coherence tomography (Conference Presentation) 用布里渊显微镜和光学相干断层扫描非接触定量胚胎发育过程中的组织生物力学(会议报告)

Optical Elastography and Tissue Biomechanics VI Pub Date : 2019-03-13 DOI: 10.1117/12.2507554

Jitao Zhang, Raksha Raghunathan, Justin R. Rippy, Chen Wu, R. Finnell, K. Larin, G. Scarcelli

{"title":"Non-contact quantification of tissue biomechanics during embryo development with Brillouin microscopy and optical coherence tomography (Conference Presentation)","authors":"Jitao Zhang, Raksha Raghunathan, Justin R. Rippy, Chen Wu, R. Finnell, K. Larin, G. Scarcelli","doi":"10.1117/12.2507554","DOIUrl":"https://doi.org/10.1117/12.2507554","url":null,"abstract":"Embryonic development involves the interplay of driving forces that shape the tissue and the mechanical resistance that the tissue offers in response. While increasing evidence has suggested the crucial role of physical mechanisms underlying embryo development, tissue biomechanics is not well understood due to the lack of techniques that can quantify the stiffness of tissue in-situ with 3D high-resolution and in a non-contact manner. In this work, we used two all-optical technique, optical coherence tomography (OCT) and Brillouin microscopy, to map the longitudinal modulus of the neural tube tissue of mouse embryo in-situ. We found the tissue stiffens significantly after the closure of the neural tube at cranial regions by comparing embryos at E 8.5 and E 9.5. In addition, we observed that the region of fusion following neural tube closure is softer than the adjacent neural folds, and the neural folds show a modulus gradient along dorsal-ventral direction. Furthermore, we found the overlaying ectoderm is much softer and more pliable than the closed neural tube, and thus can be distinguished based on its mechanical properties. In conclusion, we demonstrated the capability of OCT and Brillouin microscopy to quantify tissue modulus of mouse embryos in-situ, and observed a distinct change of tissue modulus during the closure of cranial neural tube, suggesting this method could be helpful in investigating the role of tissue biomechanics in the regulation of embryo development.","PeriodicalId":348521,"journal":{"name":"Optical Elastography and Tissue Biomechanics VI","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131714587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Brillouin microscopy: exploring niche applications (Conference Presentation) 布里渊显微镜:探索利基应用(会议报告)

Optical Elastography and Tissue Biomechanics VI Pub Date : 2019-03-13 DOI: 10.1117/12.2510894

V. Yakovlev

引用次数: 0

Adaptive optics for Brillouin micro-spectroscopy (Conference Presentation) 布里渊微光谱学的自适应光学(会议报告)

Optical Elastography and Tissue Biomechanics VI Pub Date : 2019-03-13 DOI: 10.1117/12.2506775

Eitan Edrei, G. Scarcelli

引用次数: 0

Temporal changes in corneal elasticity and shape during UV collagen cross-linking (Conference Presentation) 紫外线胶原交联过程中角膜弹性和形状的时间变化(会议报告)

Optical Elastography and Tissue Biomechanics VI Pub Date : 2019-03-13 DOI: 10.1117/12.2510337

Tueng T. Shen, R. Wallace, Liang Gao, Shaozhen Song, I. Pelivanov, Ruikang K. Wang, M. O’Donnell, Mitchell A. Kirby

引用次数: 1

The importance of corneal biomechanics in clinical practice (Conference Presentation) 角膜生物力学在临床实践中的重要性(会议报告)

Optical Elastography and Tissue Biomechanics VI Pub Date : 2019-03-13 DOI: 10.1117/12.2515717

J. Randleman

引用次数: 1

Mapping mechanical properties and structure of dentin by Brillouin spectroscopy and nonlinear optical microscopy (Conference Presentation) 用布里渊光谱和非线性光学显微镜绘制牙本质的力学性质和结构(会议报告)

Optical Elastography and Tissue Biomechanics VI Pub Date : 2019-03-13 DOI: 10.1117/12.2506858

Tijana Lainović, J. Margueritat, L. Blažić, D. Pantelic, M. Rabasović, A. Krmpot, T. Dehoux

引用次数: 1