S. Dobson, Elizabeth Halley, J. Skull, M. Metwally, B. Ola
{"title":"Reproductive outcomes and predictors for success following hysteroscopic tubal cannulation for proximal tubal disease","authors":"S. Dobson, Elizabeth Halley, J. Skull, M. Metwally, B. Ola","doi":"10.4103/ajiac.ajiac_7_20","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_7_20","url":null,"abstract":"Context: Tubal factor sub-fertility accounts for approximately 12% of IVF treatment cycles performed in the UK. Current data suggests that following hysteroscopic tubal cannulation, patients can expect a comparable LBR of 22% and spontaneous CPR of 25-27%, versus a LBR of 21% and CPR of 36.3% per cycle of IV. Our study is a l retrospective study, looking at reproductive outcomes after hysteroscopic cannulation of proximal tubal disease. Aims: investigate the effectiveness of hysteroscopic tubal cannulation (HTC) for the treatment of patients with proximal tubal obstruction (PTO). Settings and Design: Retrospective study. Methods: All patients underwent HTC for either unilateral (n= 53) or bilateral PTO (n= 33) between 2009 and 2018. Fertility outcomes were collected over following 24 months. Results: Overall CPR and live birth rate (LBR) following successful HTC was 26.9% and 22.2% respectively. Patients aged 20-35 years achieved a significantly higher CPR (38.5% vs 8.33%; Odds ratio (OR) 6.875; 95% confidence interval (CI) 1.41-33.54) and LBR (30.8% vs 8.3% OR 5.5; 95% CI 1.118-27.1) compared to 36-45 year-olds.","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134640130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Challenges with assisted reproductive technology (ART) in sub-Saharan Africa","authors":"P. Fiebai, J. Ikimalo","doi":"10.4103/ajiac.ajiac_8_22","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_8_22","url":null,"abstract":"Sub-Saharan Africa is one of the regions with the highest prevalence of infertility in the world. Despite the high prevalence of infertility in sub-Saharan Africa, it is the region with the least number of assisted reproductive technology (ART) facilities in the world. The challenges facing the rapid development of ART in sub-Saharan Africa stem from the socioeconomic, political, religious, and cultural background and the ethical issues surrounding the practice of ART. The establishment of ART centers in this subregion is a welcome development because it creates awareness and improves access to care and follow-up with the technological advancements in other regions of the world. However, the society has the responsibility to ensure that the advances made through ART are implemented in a socially responsible and acceptable manner. National governments should address the infrastructural problems such as power, roads, security, manufacturing, importation clearance, and healthcare facilities in their subregions. At the regional levels, training centers should be established across the region for proper formal training for all cadres of ART practitioners—doctors, embryologists, nurses, counsellors, and administrative staff. The governments of the various countries in sub-Saharan Africa should encourage, regulate, and control the practices of ART in line with local sociocultural norms.","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123471457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Are there possible predictors of pain during office hysteroscopy among infertile women in Port Harcourt Nigeria?","authors":"Kennedy Nyengidiki, V. Oriji, Inusa Amike","doi":"10.4103/ajiac.ajiac_2_20","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_2_20","url":null,"abstract":"Context: Invasive office procedures such as office hysteroscopy are usually carried out without analgesia as they are thought to cause minimal or no pain to the patient. Hysteroscopy has been found to be a cause of significant pain in some patients. Aims: To determine factors inherent in infertile patients experiencing pain during office hysteroscopy in Port Harcourt, Nigeria. Settings and Design: A cross-sectional comparative study amongst infertile women undergoing office hysteroscopy. Methods and Material: Assessment of Pain perceptions using a numerical pain scale in 101 women following office hysteroscopy. Demographic, Social, and gynecological factors of these patients were analysed for association with to pain perception. Statistical Analysis Used: Bivariate logistic regression analysis was conducted for associations between pain perception and suspected factors with P≤ 0.05 as statistically significant. Results: The mean age of the patients was 35.95±4.65 years. 53(52.5%) and 48(47.5%) of the patients experienced moderate/severe pain and mild/no pain respectively. Moderate/severe pain in participants was not associated with age, parity, type or period of infertility, dysmenorrhea or previous pregnancy terminations. However, it was associated with education below secondary level (OR=1.82; P value=0.21, 95%CI 0.81-4.11) and over one previous miscarriages (OR=1.11, P value = 0.948.;95% CI 0.51-2.43). Conclusions: Moderate/severe pains at office hysteroscopy occurred in more than one half of the patients increased risk of pain occurred in patients with miscarriages and those with less than secondary education. We recommend analgesia for patients undergoing office hysteroscopy.","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124592350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Regulation of assisted reproductive technology (ART) in Nigeria","authors":"P. Fiebai, K. Green","doi":"10.4103/ajiac.ajiac_9_22","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_9_22","url":null,"abstract":"","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121242607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Enforcement of In vitro fertilization standards among practitioners of ART in Nigeria","authors":"R. Ajayi","doi":"10.4103/ajiac.ajiac_5_20","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_5_20","url":null,"abstract":"","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125449007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Counseling in assisted reproductive technology","authors":"Etang Abang","doi":"10.4103/ajiac.ajiac_2_21","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_2_21","url":null,"abstract":"The background history of counseling in assisted reproductive technology (ART) relates to when technology was introduced into the infertility treatment of clients. The public reaction then was intense on concern over the vulnerability of potential users and the welfare of children either created or affected by it. As a response, the development of Human Fertilization and Embryology Act (HFEA) in 1990 established infertility counseling with recommendations to address the public perception of moral and social acceptability of ART by the society. The recommendations outlined requirements for clinics offering infertility treatment to individuals and couples to provide counseling for the associated symptoms and treatment consequences that clients may experience with ART. The purpose, definition, indications, types, and scope for counseling in ART were also addressed. Infertility counseling in ART incorporates a clinical team approach consisting of the fertility doctor, fertility nurses, professional counselors and embryologist who through information empower and support clients to cope well with the infertility experiences.","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114772024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fetal self-defense or maternal immune tolerance","authors":"M. Raturi","doi":"10.4103/ajiac.ajiac_8_20","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_8_20","url":null,"abstract":"","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123632795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kanchan Murarka, D. Goenka, M. L. Goenka, Parth Shah
{"title":"A rare case of 46XX,t(X;11)(q24;q23.3) with premature ovarian insufficiency","authors":"Kanchan Murarka, D. Goenka, M. L. Goenka, Parth Shah","doi":"10.4103/ajiac.ajiac_9_17","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_9_17","url":null,"abstract":"Here, we report a rare case of chromosomal abnormality with translocation between bands Xq24 and 11q23.3 leading to premature ovarian insufficiency (POI). POI can occur due to various causes. Studies have shown that 10%–12% of women with POI have chromosomal abnormalities. This patient presented to us with secondary amenorrhea for the past 3 years. She had attained menarche at 13 years and had regular menstrual cycles for 9 years before suffering from secondary amenorrhea. She had no family history of POI. Her karyotype revealed 46XX,t(X;11)(q24;q23.3). Other investigations showed hypoestrogenism, raised follicle-stimulating hormone, low volume ovaries, small sized uterus, and cholelithiasis. Laparoscopic cholecystectomy was done along with pelvic laparoscopy and hysteroscopy. Sequential estrogen and progesterone was given to the patient for 3 months. Following that, in vitro fertilization with oocyte donation was done which resulted into positive beta-human chorionic gonadotropin.","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129696993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Omokanye, A. Olatinwo, L. Saadu, S. Biliaminu, K. Durowade, A. Panti
{"title":"Assisted reproductive technology: Experience from a public tertiary institution in north central Nigeria","authors":"L. Omokanye, A. Olatinwo, L. Saadu, S. Biliaminu, K. Durowade, A. Panti","doi":"10.4103/ajiac.ajiac_3_17","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_3_17","url":null,"abstract":"Background: According to the World Health Organization, more than 180 million couples globally suffer from infertility, the majority being residents of developing countries. Assisted reproductive technologies (ARTs) offer a chance at parenthood to couples, who until recently would have had no hope of having a “biologically related” child. Objectives: This study aimed to determine pregnancy outcomes following assisted conception. Materials and Methods: This is a prospective study of 104 clients who underwent the procedure of ART between January 1, 2012 and December 31, 2016 at the ART unit of University of Ilorin Teaching Hospital, Ilorin, Nigeria. Results: Of the 510 clients who had infertility consultation at the ART clinic, 104 (20.4%) underwent ART procedures. The patients aged 27–46 years with a mean age of 33 ± 4.0 years. More than half (58.7%) had primary infertility. Their duration of infertility ranged from 1 to 20 years (4.6 ± 2.9 years). Majority (81.7%) had conventional in vitro fertilization while 19 (18.3%) had intracytoplasmic sperm injection. Thirteen (12.5%) cases of cycle cancellation and 11 (11.7%) cases of mild-to-moderate ovarian hyperstimulation syndrome were recorded. The clinical pregnancy rate per cycle started was 39.4%. However, 9/41 (22%) resulted in spontaneous miscarriages and 32 (6 sets of twin, 25 singleton, and 1 high-order multiple births) were successfully delivered, giving a live birth rate per cycle started of 30.8%. Pregnancy outcomes were not significantly affected by age of the women, types of infertility, and duration of infertility (P > 0.05). Conclusion: The outcomes of ART procedures in a resource-limited country like ours are encouraging. This underscores the need to encourage ART in public tertiary institutions in Nigeria through the support of government and nongovernmental organizations for the benefit of infertile couples who were hitherto hopeless.","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129565379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}