African Journal for Infertility and Assisted Conception最新文献

{"title":"AFRH Conference 2021 Abstracts","authors":"","doi":"10.4103/2468-8452.355650","DOIUrl":"https://doi.org/10.4103/2468-8452.355650","url":null,"abstract":"","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126714200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Approach to management of submucous fibroids by gynaecological endoscopy surgeons/trainees in Nigeria","authors":"L. Akinola, J. Okohue, J. Ikechebelu, C. Alabi, A. Olumodeji","doi":"10.4103/ajiac.ajiac_5_21","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_5_21","url":null,"abstract":"Hysteroscopic myomectomy is the treatment of choice for submucous fibroid. Studies have shown positive impacts on recurrent pregnancy loss and infertility. Our survey documents approach to managing submucous fibroids by gynaecologists with special endoscopy skills among members of the Association of Gynaecological Endoscopy Surgeons of Nigeria (AGES). Materials and Methods: A questionnaire-based-cross-sectional survey of members of the Association of Gynaecological Endoscopy Surgeons of Nigeria between December 31, 2019, and January 21, 2020, using the SurveyMonkey platform. Results: One hundred and forty-one of 210 members participated; a response rate of 67.1%. Of the respondents, 130 (92.2%) were consultants, 10 (7.1%) were senior registrars. Hysteroscopy training varied from basic/advanced certificate courses to post-fellowship training in endoscopy. Sixty-nine (53.1%) had been in practice for >10 years. Monthly, 60.7% (82/135) performed <5 hysteroscopic procedures; 25.2% (34/135) 6–10; 9.6% (13/135) 11–20; 3.7% (5/135) performed 21–30 and 0.7% (1/135) >40. Up to 64.2% (86/134) use 2D transvaginal scans to diagnose submucous fibroid, 37.5% (51/136) combine ultrasound and hysterosonography or hysterosalpingography. About 65.1%, (82/126), 35.9% (47/131), 12.2% (16/131), respectively, use FIGO, the International Society for Gynaecologic Endoscopy/ European Society of Human Reproduction and Embryology (ISGE/ESHRE) or use none of these for classifying submucous fibroids. Glycine was preferred for monopolar resection by 52.5% (62/118), while 59.7% (71/119) use saline for bipolar resection. About 93.2% (109/117) will not consider sterile water for bipolar resection. About 70.5% (86/122) regularly monitor fluid deficit, 17.6% (22/125) do not (due to lack of a monitoring device). Also, 14.4% (18/125) do not (because they use <3 L of distention media). For uterine cavity distention, 52% (64/123) use fluid pressure pumps, 28.6% (34/129) use gravity, while 25.4% (31/122) use Hysteromat or other fluid management equipments. About 3.7% (4/109) conveniently resect type-2 submucous fibroids in >2 hysteroscopic procedures, while 20.2% (23/114) and 23.2% (26/112), respectively, in one or two hysteroscopic approaches. Notably, 50.4% (63/125) refer such patients to experienced gynaecologists. None use barrier gels-only anti-adhesion therapy; 78.5% (95/121) combine balloon catheter/intrauterine device with oestrogen/progesterone tablets. About 38% (40/105) offers no 2nd-look follow-up. About 45% (52/115) had experienced complications, including uterine perforation during operative hysteroscopy. Conclusion: Hysteroscopic myomectomy is increasingly being used by AGES-registered gynaecologists to manage submucous fibroids, a very common cause of morbidity and subfertility in women. AGES can significantly and positively impact the trends of gynecologic endoscopic training, skills and practices among Nigerian doctors.","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"65 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133154723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is male factor infertility rising? Another side of the equation from an in vitro fertilization clinic in southwestern Nigeria","authors":"G. Obajimi, C. Kolade, A. Aladejare","doi":"10.4103/ajiac.ajiac_1_21","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_1_21","url":null,"abstract":"Background: Male factors account for about half of the causes of infertility and a high premium is placed on childbirth and rearing in developing countries. With the introduction of assisted conception, the burden of care for managing male infertility has shifted to the female partner. Male infertility is generally evaluated via seminal fluid analysis which includes parameters such as concentration, motility, and morphology. The etiology of male infertility is multifactorial, and majority of cases are known to be idiopathic. Materials and Methods: A descriptive cross-sectional study of 77 male partners of infertile couples presenting to an in vitro fertilization clinic in Ibadan, Nigeria, between January 1 and June 30, 2019. Participants were selected consecutively at their first consultation visit. A self-administered questionnaire was completed by each participant comprising socio-demographic information, results of laboratory screening, and seminal fluid analysis. Data was analyzed using the Statistical Package for Social Sciences (SPSS, IBM, NY), version 22. Descriptive statistics were generated, and presented with the aid of a bar chart, pie chart, and frequency tables. Results: The average age of the participants was 43.64 ± 3.1 years and 97.4% (75) were in a stable relationship. Duration of infertility ranged between 3 and 17 years with an average of 7.6 ± 1.8 years. Human immunodeficiency virus, syphilis, hepatitis B, and hepatitis C were diagnosed in 3%, 4%, 5%, and 1%, respectively. Over half of the participants had semen volume and liquefaction time of 1-2 mL and 15-30 min, respectively. 34 men (44.1%) had normal semen parameters while the remaining 43 (55.9%) had various forms of abnormalities. Mid-piece defects were the most prevalent morphological defects and were found in 70 men (90.9%) while immature spermatozoa were found in 38 men (49.4%). Only one participant had azoospermia (1.3%). Conclusion: The impact of male factor infertility cannot be over-emphasized. Male contribution to infertility is thought to be rising and this study from male partners of infertile couples revealed semen abnormalities in over 50% of the participants. Addressing preventable causes of male infertility through health awareness and lifestyle modifications are important steps towards engendering optimal reproductive health.","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"57 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122843077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum homocystein and C-reactive protein in predicting outcome of in-vitro fertilization in infertile women with polycystic ovary syndrome","authors":"Kingsley Onwumere, B. Musa, A. Kolawole, N. Ameh, I. Wada, Christopher Danga, Abdurrahman EL-Fulaty, B. Kehinde","doi":"10.4103/ajiac.ajiac_1_22","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_1_22","url":null,"abstract":"Background: Polycystic ovarian syndrome (PCOS) is the most common cause of anovulatory infertility. Hyperhomocysteinemia (HHcy), is common in PCOS and reportedly causes poor oocyte quality and recurrent pregnancy loss. The aim of this report is to assess serum concentrations of Hcy and its association with C-reactive protein (CRP) levels in patients with PCOS undergoing in-vitro fertilization (IVF) treatment. Materials and Methods: Eighty-five women of reproductive age 25–35 years were included in this study, comprising 30 infertile women with PCOS (group 1), 30 infertile women without PCOS (group 2), and 25 matched apparently healthy women without infertility or PCOS (group 3). The serum Hcy and CRP levels were measured using the TOSOH AIA 360 enzyme immunoassay method and Raytor6000 Semi-Autoanalyzer, respectively. Results: The median CRP values were 15.13 (4.43–21.77 mg/L), 3.42 (2.50–8.04 mg/L), and 1.45 (0.97–3.51 mg/L) for Group 1, Group 2, and Group 3, respectively. The median Hcy values were 19.75 (15.50–39.98 μmol/L), 10.00 (9.38–10.92 μmol/L), and 10.00 (8.93–10.93 μmol/L) for Group 1, Group 2, and Group 3, respectively. The differences between Group 1 and Group 2, and between Group 1 and Group 3 median Hcy values were significant for both CPR and Hcy (P < 0.0001). There was a significant association between embryo qualities and the groups. Similarly, there were more of higher (Grades 4 and 5) embryo qualities in Group 3. Conclusion: Serum Hcy and CRP levels estimation should be included in the evaluation and management of patients with PCOS undergoing in-vitro fertilization.","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121345595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SARS-CoV-2 and male infertility","authors":"R. Baid","doi":"10.4103/ajiac.ajiac_3_21","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_3_21","url":null,"abstract":"","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126969332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of transvaginal sonography with hysteroscopy in evaluation of uterine cavity anomalies for female Nigerian patients","authors":"O. Ray-Offor, E. Ray-Offor","doi":"10.4103/AJIAC.AJIAC_16_20","DOIUrl":"https://doi.org/10.4103/AJIAC.AJIAC_16_20","url":null,"abstract":"Introduction: Transvaginal sonography (TVS) and hysteroscopy are useful in investigating causes of intrauterine pathologies. Aim: To compare the diagnostic yield of TVS with hysteroscopy for the evaluation of uterine cavity anomalies in female Nigerian patients. Materials and Methods: This is a cohort study of patients referred with infertility and abnormal uterine bleeding that were consecutively evaluated with TVS by a radiologist and confirmed by hysteroscopy at a multi-disciplinary endoscopy centre in Port Harcourt metropolis, Nigeria. Study period was from June 2014 to November 2019. Variables collated were sociodemographic, radiological, and endoscopic findings, sensitivity, specificity, and predictive values. Statistical analysis was with SPSS version 20. Results: A total of 99 patients had hysteroscopy but 52 patients included in study. The age of patients ranged from 25 – 56 years; mean age of 39.4 ± 6.0 years. The sensitivity and specificity of TVS for detection of intracavitary uterine anomalies were 78.7% and 100% respectively. The positive and negative predictive values were 100% and 33.3% respectively. There was additional detection of intramural ± subserosa myoma by TVS alone in 28(53.8%) patients and ovarian cysts in 5(9.6%) patients. Conclusion: TVS is an effective screening tool for preoperative triage of women with infertility and abnormal uterine bleeding requiring therapeutic intervention for intracavitary uterine anomalies. Hysteroscopy remains the gold standard for diagnosis of endometrial pathologies.","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"40 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120824992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AFRH Conference 2020 Abstracts","authors":"","doi":"10.4103/2468-8452.322998","DOIUrl":"https://doi.org/10.4103/2468-8452.322998","url":null,"abstract":"","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132660799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of body mass index with semen parameters and testicular volume in men with infertility","authors":"S. Abu, T. Atim, H. kolade-Yunusa, Kenenna Obiatuegwu, F. Magnus, N. Dakum","doi":"10.4103/ajiac.ajiac_12_20","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_12_20","url":null,"abstract":"Background: The question of whether body mass index (BMI) affects semen quality and male fertility is controversial and available evidence are inconclusive and poorly documented in Nigeria and Africa by extension. Aim and Objectives: The study was conducted to correlate body mass index, sperm parameters and testicular volume in men with infertility presenting to the urology division, University of Abuja Teaching Hospital, Gwagwalada Abuja. Material and Methods: This was a prospective cross- sectional study. Male patients with infertility who presented to Urology Division University of Abuja Teaching hospital were recruited into the study. The weight of the subjects were measured using digital scale in kilogram and the height of the subjects were measured in meters and BMI calculated. The testicular volumes of all the subjects were measured using Prader orchidometer. The semen samples were collected by the process of masturbation on day five of sexual abstinence and analyzed according to WHO 2010 criteria. Collected data were analyzed using SPSS version 20. Results: The mean BMI of the subjects was 25.97±4.57kg/m2 with a range of 18.80-44kg/m2. The mean testicular volume using the orchidometer was 12.02±3.55ml. Subjects with normal BMI were 39(45.9%), overweight 32(37.6%) and 14(16.5%) of the subjects were obese. There was strong significant negative correlation between BMI and semen concentration using Pearson correlation (r=-0.591, P=0.000), and sperm motility (r=-0.569, P=0.000). Conclusion: Although it is difficult to generalize our results to the overall population, our results suggest that increased BMI has a deleterious effect on semen concentration and sperm motility. Therefore, to ensure maximum fertility potential, patients may be advised to prevent excessive weight gain as well as reduce weight amongst the obese.","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132191280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression","authors":"Lanre Toki","doi":"10.4103/ajiac.ajiac_9_20","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_9_20","url":null,"abstract":"","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127928931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Covid-19 pandemic: Impacts survey of fertility practitioners in Nigeria","authors":"L. Akinola","doi":"10.4103/ajiac.ajiac_4_20","DOIUrl":"https://doi.org/10.4103/ajiac.ajiac_4_20","url":null,"abstract":"Background: COVID-19 pandemic has created a huge disruption to the activities of physicians and other healthcare providers all over the world. Fertility centers, fertility practitioners and patients alike are not left out. Infertile couples and families also face significant disruptions to their treatment schedules, financial plans as well as uncertainty about when their fertility treatments will begin. This survey evaluates the impacts that COVID-19 pandemic will have on the budgetary and operational activities of Fertility Centre's and practitioners in Nigeria. Methodology: A question-based, cross-sectional survey of registered fertility practitioners of the Association for Fertility and Reproductive Health of Nigeria (AFRH) carried out on the 10TH to 15TH of April 2020. Results: Majority of the respondents felt that their fertility centers made a good adaptation to the new working environment. Majority agreed that services have been negatively impacted, while 64.42% of responding practitioners felt the pandemic had not resulted to staff retrenchments. Also, majority believe that business continuity and plan is not been disrupted by the pandemic. A third of the respondents use travel and exposure histories, physical examinations and taking temperature for diagnostic assessments. AFRH and Nigerian Center for Disease Control (NCDC) performance and response to Covid-19 pandemic were rated to be above average. Conclusion: Majority of the AFRH fertility practitioners surveyed felt that Covid-19 pandemic and its containment strategies negatively impacted work, services and budgetary needs of fertility practitioners in Nigeria, with no significant impact on staff employments. Response and guidance from the Association for fertility and reproductive Health and the NCDC towards curtailing the spread of Covid-19 infections to their members and the Nigerian communities, respectively, were rated above average.","PeriodicalId":348163,"journal":{"name":"African Journal for Infertility and Assisted Conception","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128812306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}