{"title":"Chronische inflammatorische demyelinisierende Polyradikuloneuropathie (CIDP)","authors":"Barbara Kaulen, Laura Hagemann, H. Lehmann","doi":"10.1055/a-1902-2911","DOIUrl":"https://doi.org/10.1055/a-1902-2911","url":null,"abstract":"Die chronische inflammatorische demyelinisierende Polyradikuloneuropathie (CIDP) ist die häufigste chronische Autoimmunerkrankung des peripheren Nervensystems. Sie ist häufig schwierig zu diagnostizieren. Die CIDP ist mittlerweile mittels verschiedener Immuntherapeutika gut behandelbar. In diesem Beitrag wird die Diagnose und Therapie der CIDP anhand eines typischen Fallbeispiels erläutert.","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":" 8","pages":"369 - 382"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138615088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Myasthenia gravis I: Zilucoplan als neue Therapieoption?","authors":"","doi":"10.1055/a-2094-5260","DOIUrl":"https://doi.org/10.1055/a-2094-5260","url":null,"abstract":"","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":"102 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138608852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biomarker und Bildgebung in der Diagnose von Demenzen","authors":"Chi-un Choe, Holger Jahn","doi":"10.1055/a-1917-7368","DOIUrl":"https://doi.org/10.1055/a-1917-7368","url":null,"abstract":"Die Anzahl Demenzkranker nimmt aufgrund des demografischen Wandels in Deutschland stetig zu und wird im Jahr 2050 fast 3,2 Millionen Menschen betragen. Bisher diente die Diagnostik bei der Demenz insbesondere dem Ausschluss von Differenzialdiagnosen, da die therapeutische Konsequenz durch lediglich symptomatisch wirksame Medikamente limitiert war. Die Entwicklung von therapeutischen Antikörpern wird spezifische Biomarker in der klinischen Routine unabdingbar machen. In den letzten Jahren gibt es deshalb eine Entwicklung von einer rein klinisch-symptomatologischen Diagnosestellung hin zu einer biomarkerbasierten Einteilung.","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":"101 9","pages":"385 - 400"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138607837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Post-Covid-Syndrom: Auf der Suche nach pathophysiologischen Grundlagen","authors":"","doi":"10.1055/a-2094-5215","DOIUrl":"https://doi.org/10.1055/a-2094-5215","url":null,"abstract":"","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":" 35","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138614285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nils Nellessen, J. Kukolja, Olaf Bick, Stefan Christian Mück
{"title":"Der L-Dopa-Test: Eine kleinschrittige Anleitung","authors":"Nils Nellessen, J. Kukolja, Olaf Bick, Stefan Christian Mück","doi":"10.1055/a-2135-1989","DOIUrl":"https://doi.org/10.1055/a-2135-1989","url":null,"abstract":"Der L-Dopa-Test wird häufig im Rahmen der Diagnostik und Differenzialdiagnostik des Parkinson-Syndroms eingesetzt. Diese Schritt-für-Schritt-Anleitung soll im klinischen Alltag eine Hilfestellung bei der konkreten Durchführung und Interpretation bieten.","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":" 24","pages":"314 - 324"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138614834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Akuter Kopfschmerz","authors":"J. Holle","doi":"10.1055/a-2060-8986","DOIUrl":"https://doi.org/10.1055/a-2060-8986","url":null,"abstract":"Ein Viertel aller neurologischen Notfallpatienten werden unter dem Leitsymptom Kopfschmerz vorstellig. In über 90% liegen sog. primäre Kopfschmerzen vor, die harmlos sind und meist keiner dezidierten apparativen Diagnostik bedürfen. Dem gegenüber stehen zahlreiche zwar seltenere, jedoch teils lebensbedrohliche Krankheitsentitäten. Ziel des vorliegenden Beitrags ist es, praktikable Handlungsempfehlungen zu geben, um einerseits therapiebedürftige sekundäre Formen nicht zu übersehen, anderseits Überdiagnostik zu vermeiden.","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127534550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}