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Update Amyotrophe Lateralsklerose – Diagnostik und Therapie 肌萎缩侧索硬化症的最新诊断和治疗
Neurologie up2date Pub Date : 2024-12-01 DOI: 10.1055/a-2133-1668
Bogdan Bjelica, Susanne Petri, Camilla Wohnrade
{"title":"Update Amyotrophe Lateralsklerose – Diagnostik und Therapie","authors":"Bogdan Bjelica, Susanne Petri, Camilla Wohnrade","doi":"10.1055/a-2133-1668","DOIUrl":"https://doi.org/10.1055/a-2133-1668","url":null,"abstract":"Amyotrophe Lateralsklerose (ALS) ist die häufigste Motoneuronerkrankung mit Beginn im Erwachsenenalter. Trotz fortschreitender Entschlüsselung der molekularen Pathogenese sind verlaufsmodifizierende Therapieoptionen bei der sporadischen ALS bisher begrenzt, für einige genetische Formen gibt es jedoch äußerst vielversprechende neue Ansätze. Eine multidisziplinäre symptomatische Behandlung kann wesentlich zum Erhalt der Lebensqualität beitragen.","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":"07 04","pages":"361-377"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147882642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Myasthenia gravis I: Zilucoplan als neue Therapieoption? 重症肌无力 I：齐鲁霉素作为新的治疗选择？
Neurologie up2date Pub Date : 2023-12-01 DOI: 10.1055/a-2094-5260
{"title":"Myasthenia gravis I: Zilucoplan als neue Therapieoption?","authors":"","doi":"10.1055/a-2094-5260","DOIUrl":"https://doi.org/10.1055/a-2094-5260","url":null,"abstract":"","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":"102 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138608852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SOP Neuroborreliose SOP 神经硼砂
Neurologie up2date Pub Date : 2023-12-01 DOI: 10.1055/a-2181-4238
H. Lehmann
{"title":"SOP Neuroborreliose","authors":"H. Lehmann","doi":"10.1055/a-2181-4238","DOIUrl":"https://doi.org/10.1055/a-2181-4238","url":null,"abstract":"","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":"94 ","pages":"310 - 313"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138615084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronische inflammatorische demyelinisierende Polyradikuloneuropathie (CIDP) 慢性炎症性脱髓鞘多发性神经病（CIDP）
Neurologie up2date Pub Date : 2023-12-01 DOI: 10.1055/a-1902-2911
Barbara Kaulen, Laura Hagemann, H. Lehmann
{"title":"Chronische inflammatorische demyelinisierende Polyradikuloneuropathie (CIDP)","authors":"Barbara Kaulen, Laura Hagemann, H. Lehmann","doi":"10.1055/a-1902-2911","DOIUrl":"https://doi.org/10.1055/a-1902-2911","url":null,"abstract":"Die chronische inflammatorische demyelinisierende Polyradikuloneuropathie (CIDP) ist die häufigste chronische Autoimmunerkrankung des peripheren Nervensystems. Sie ist häufig schwierig zu diagnostizieren. Die CIDP ist mittlerweile mittels verschiedener Immuntherapeutika gut behandelbar. In diesem Beitrag wird die Diagnose und Therapie der CIDP anhand eines typischen Fallbeispiels erläutert.","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":" 8","pages":"369 - 382"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138615088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomarker und Bildgebung in der Diagnose von Demenzen 诊断痴呆症的生物标记物和成像技术
Neurologie up2date Pub Date : 2023-12-01 DOI: 10.1055/a-1917-7368
Chi-un Choe, Holger Jahn
{"title":"Biomarker und Bildgebung in der Diagnose von Demenzen","authors":"Chi-un Choe, Holger Jahn","doi":"10.1055/a-1917-7368","DOIUrl":"https://doi.org/10.1055/a-1917-7368","url":null,"abstract":"Die Anzahl Demenzkranker nimmt aufgrund des demografischen Wandels in Deutschland stetig zu und wird im Jahr 2050 fast 3,2 Millionen Menschen betragen. Bisher diente die Diagnostik bei der Demenz insbesondere dem Ausschluss von Differenzialdiagnosen, da die therapeutische Konsequenz durch lediglich symptomatisch wirksame Medikamente limitiert war. Die Entwicklung von therapeutischen Antikörpern wird spezifische Biomarker in der klinischen Routine unabdingbar machen. In den letzten Jahren gibt es deshalb eine Entwicklung von einer rein klinisch-symptomatologischen Diagnosestellung hin zu einer biomarkerbasierten Einteilung.","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":"101 9","pages":"385 - 400"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138607837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-Covid-Syndrom: Auf der Suche nach pathophysiologischen Grundlagen 后科维德综合征：寻找病理生理基础
Neurologie up2date Pub Date : 2023-12-01 DOI: 10.1055/a-2094-5215
{"title":"Post-Covid-Syndrom: Auf der Suche nach pathophysiologischen Grundlagen","authors":"","doi":"10.1055/a-2094-5215","DOIUrl":"https://doi.org/10.1055/a-2094-5215","url":null,"abstract":"","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":" 35","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138614285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Der L-Dopa-Test: Eine kleinschrittige Anleitung 左旋多巴检测：逐步指南
Neurologie up2date Pub Date : 2023-12-01 DOI: 10.1055/a-2135-1989
Nils Nellessen, J. Kukolja, Olaf Bick, Stefan Christian Mück
{"title":"Der L-Dopa-Test: Eine kleinschrittige Anleitung","authors":"Nils Nellessen, J. Kukolja, Olaf Bick, Stefan Christian Mück","doi":"10.1055/a-2135-1989","DOIUrl":"https://doi.org/10.1055/a-2135-1989","url":null,"abstract":"Der L-Dopa-Test wird häufig im Rahmen der Diagnostik und Differenzialdiagnostik des Parkinson-Syndroms eingesetzt. Diese Schritt-für-Schritt-Anleitung soll im klinischen Alltag eine Hilfestellung bei der konkreten Durchführung und Interpretation bieten.","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":" 24","pages":"314 - 324"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138614834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Akute Rücken- und Nackenschmerzen: Opioid-Analgetika sicher und wirksam? 急性背部和颈部疼痛：阿片类镇痛药是否安全有效？
Neurologie up2date Pub Date : 2023-12-01 DOI: 10.1055/a-2147-2259
{"title":"Akute Rücken- und Nackenschmerzen: Opioid-Analgetika sicher und wirksam?","authors":"","doi":"10.1055/a-2147-2259","DOIUrl":"https://doi.org/10.1055/a-2147-2259","url":null,"abstract":"","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":"360 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138625828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morbus Alzheimer: Antikörper Solanezumab ohne Wirkung im präklinischen Stadium 阿尔茨海默病：索拉尼珠单抗抗体在临床前阶段没有效果
Neurologie up2date Pub Date : 2023-12-01 DOI: 10.1055/a-2147-2306
{"title":"Morbus Alzheimer: Antikörper Solanezumab ohne Wirkung im präklinischen Stadium","authors":"","doi":"10.1055/a-2147-2306","DOIUrl":"https://doi.org/10.1055/a-2147-2306","url":null,"abstract":"","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":" 76","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138612032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple Sklerose: Disease Modifying Drugs (DMDs) in der Schwangerschaft? 多发性硬化症:施旺格Schwangerschaft的疾病修饰药物(dmd) ?
Neurologie up2date Pub Date : 2023-06-01 DOI: 10.1055/a-2006-1888
{"title":"Multiple Sklerose: Disease Modifying Drugs (DMDs) in der Schwangerschaft?","authors":"","doi":"10.1055/a-2006-1888","DOIUrl":"https://doi.org/10.1055/a-2006-1888","url":null,"abstract":"","PeriodicalId":345587,"journal":{"name":"Neurologie up2date","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126371192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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