International Journal of Recent Surgical and Medical Sciences最新文献

{"title":"Transmural ischemic bowel necrosis in a patient with Kabuki syndrome: a case report","authors":"Jorge Gutiérrez González, Oscar Humberto Mendoza-Hernández, Juventino Tadeo Guerrero-Zertuche, Gustavo Dragustinovis-Hinojosa, Néstor Veriel Méndez-Huerta, Gerardo Enrique Muñoz-Maldonado","doi":"10.32457/ijmss.v10i3.2219","DOIUrl":"https://doi.org/10.32457/ijmss.v10i3.2219","url":null,"abstract":"Kabuki syndrome (KS) is a rare genetic disorder in which mutations in the KMT2D or KDM6A genes result in a wide spectrum of clinical manifestations including development and growth delay; intellectual dysfunction; craniofacial dysmorphism; and various systemic structural and functional defects. We present the case of a 16-year-old male, diagnosed with KS in his infancy. He presented with acute diffuse abdominal pain, accompanied by distension, nausea and clinical data suggestive of intestinal obstruction. After radiological confirmation, focal intestinal necrosis was identified on exploratory surgery, so he underwent intestinal resection and ileostomy in shotgun. The final diagnosis was transmural intestinal ischemic necrosis with acute inflammatory process and serofibrinous peritonitis.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136314031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vol. 10 No. 3 (2023): August, 2023","authors":"","doi":"10.32457/ijmss.v10i3","DOIUrl":"https://doi.org/10.32457/ijmss.v10i3","url":null,"abstract":"","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136314032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimal change disease associated with IgA nephropathy “a rare clinical spectrum”: Case report","authors":"Juan Santiago Serna-Trejos, Laura Carolina Neira–Ruiz, Stefanya Geraldine Bermúdez–Moyano, Jennifer Alejandra Hurtado-Leiton, Diego Andrés González-Sánchez","doi":"10.32457/ijmss.v10i3.2212","DOIUrl":"https://doi.org/10.32457/ijmss.v10i3.2212","url":null,"abstract":"Minimal change disease (MCD) is one of the main causes of idiopathic nephrotic syndrome, manifesting with intense proteinuria leading to edema and intravascular volume depletion, characterized by the absence of alterations in light microscopy and the presence of effacement of the podocyte processes in electron microscopy. Although the cause is unknown, it is believed that due to an immunologic dysregulation and modifications of the podocyte and of the proteins that constitute the cytoskeleton of this one and of the filtration diaphragm, generating an alteration in the integrity of the glomerular basement membrane and, therefore, conditioning the presence of proteinuria. IgA nephropathy (IgAN) is the most common mesangial proliferative glomerulopathy in developed countries and one of the main causes of chronic kidney disease and renal failure in Asian population, characterized by the presence of mesangial IgA deposits. The clinical presentation is extremely variable, ranging from isolated dysmorphic microhematuria to chronic deterioration of renal function. We present a rare case of these two primary glomerulopathies concomitantly in one patient. This is intended to increase medical sensitivity in the diagnosis of the coexistence of these two primary glomerulopathies as atypical presentations in clinical practice.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136314042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Mediterranean diet as a healthy dietary model and its impact on the immune system and intestinal microbiota","authors":"Patricio Salazar, Adriana Pedreañez","doi":"10.32457/ijmss.v10i3.2242","DOIUrl":"https://doi.org/10.32457/ijmss.v10i3.2242","url":null,"abstract":"The relationship between nutrition and immunity is very complex, because each phase of the immune response can be affected by the lack of essential nutrients such as vitamins and minerals. In addition, it has been described that the most prevalent non-communicable diseases worldwide, such as metabolic syndrome, diabetes mellitus, cardiovascular diseases and cancer, underlie the activation of inflammatory mechanisms, which can compromise immune functions, often caused or accompanied by alterations in nutritional patterns and intestinal microbiota. In this context, it is clear that diet is a key modulator of the immune system and much interest is emerging in the area of nutrition as a means of treatment and prevention. The Mediterranean diet has been widely described as positively influencing and is proposed not only as a potential tool in the clinical management of different diseases, but also for global health promotion. Therefore, the aim of this review is to address the current knowledge on the regulatory role of the nutritional components present in the Mediterranean diet on the immune system and the intestinal microbiota.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136314043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Efficacy of Tirzepatide, Teneligliptin, and Empagliflozin in HbA1c Reduction in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis","authors":"Jordan Llerena-Velastegui, Fabian Delgado-Quijano, Martin Trujillo-Delgado, Cecibel Villacis-Lopez, Anthony Fernandez-Arcos, Gerson Santafe-Abril, Claudia Hurtado-Alzate, Karen Benitez-Acosta","doi":"10.32457/ijmss.v10i3.2263","DOIUrl":"https://doi.org/10.32457/ijmss.v10i3.2263","url":null,"abstract":"This study’s objective was to evaluate the effectiveness of three different families of drugs (Empagliflozin [an SGLT-2 inhibitor], Tirzepatide [a GLP-1 receptor co-agonist], and Teneligliptin [DPP-4 inhibitor] used in the treatment of type 2 diabetes in lowering HbA1c levels in people with type 2 diabetes mellitus (T2DM). The effectiveness of different families of diabetic drugs was assessed using a meta-analytic approach. Data were gathered from a variety of research publications using ICTRP, CT.gov, and PubMed databases. The data were analyzed, and conclusions were drawn using forest plots. Teneligliptin (a DPP-4 Inhibitor) substantially lowered HbA1c levels in T2DM patients compared to other classes of T2DM drugs with a P-value of 0.0002 and 95% CI -0.63 [-0.97 to -0.30] after reviewing many pertinent articles. The pooled data analysis showed that Tirzepatide and Empagliflozin did not significantly lower HbA1c levels, with the P-value for Tirzepatide being P = 0.55 and for Empagliflozin, it was P = 0.64. According to our research, Teneligliptin may be more effective than Empagliflozin and Tirzepatide as a monotherapy for lowering HbA1c levels in T2DM patients. To corroborate these findings, further research studies are required.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136314045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term Plasmapheresis for Cholestatic Pruritus","authors":"Erik Sanson, Luke J Richard, Margarita N German, William N Rose","doi":"10.25259/ijrsms-2022-2-12","DOIUrl":"https://doi.org/10.25259/ijrsms-2022-2-12","url":null,"abstract":"Cholestatic pruritus is commonly associated with many hepatobiliary disorders and can be typically controlled with conventional treatment. Therapeutic plasma exchange (TPE) has shown success in improving untreatable cholestatic pruritus with great success. We report on the use of TPE to alleviate debilitating pruritus in one patient with a two-year history of chronic pruritus refractory to conventional treatment. The patient presented with an acute onset of diffuse pruritus that did not fully respond to first or second-line treatments, including bile acid sequestrants. Pruritus significantly affected her quality of life, interfering with daily activity, causing insomnia and weight loss. Due to the severity of her symptoms, biweekly TPE with 5% albumin infusions were initially trialed. Patient found symptoms to be much improved until about the fifth day after each TPE. TPEs were scheduled twice per week alternating with once per week. TPE appeared to be an effective treatment for this patient with chronic cholestatic pruritus. For our patient, TPE seemed to provide relief for about 3-5 days after each TPE.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72607181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Empty Nose Syndrome with Unilateral Ethmoidal Mucopyocoele – An Extremely Rare Presentation","authors":"Sama Rizvi, Rishita Kalra, V. K. Pathak, P. Nayak","doi":"10.25259/ijrsms-2021-5-7","DOIUrl":"https://doi.org/10.25259/ijrsms-2021-5-7","url":null,"abstract":"\u0000 \u0000Empty nose syndrome (ENS) is a poorly understood and rare iatrogenic disorder resulting from the destruction of normal nasal tissue. ENS is a recognized complication after turbinate excision. These patients suffer from endonasal crusting and dryness and a paradoxical sensation of nasal obstruction. These complications of ENS predispose these patients to recurrent sino-nasal infections. \u0000\u0000\u0000\u0000\u0000Here we have reported the case of a 20-year-old female with right-sided nasal obstruction and headache. On diagnostic nasal endoscopy (DNE), the right nasal cavity was devoid of all anatomical landmarks. A hidden ethmoidal mucopyocoele was identified on radiological evaluation . This was drained surgically. Patient’s symptoms improved drastically postoperatively. \u0000\u0000\u0000 \u0000Despite the fact that occurrence of rhino-sinusitis is common in patients of ENS, a mucocoele or mucopyocoele has never been reported previously. To the best of our knowledge, this is the first ever reported case of ENS with ethmoidal mucopyocoele in a young, immuno-competent patient. \u0000","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79618397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Audit of Operated Patients in a Tertiary Care Hospital in Karachi, Pakistan","authors":"Huma Akhtar, H. H. Ahmed, Kanwal Irshad, Muhammad Jamaluddin","doi":"10.25259/ijrsms-2020-12-4","DOIUrl":"https://doi.org/10.25259/ijrsms-2020-12-4","url":null,"abstract":"\u0000 \u0000To audit operated patients in emergency and electively from 1st January 2018 to 31st December 2019 in all three surgical departments to know the outcome of the patients at a tertiary care hospital in Karachi, Pakistan.\u0000\u0000\u0000\u0000A retrospective study conducted in all three Abbasi Shaheed Hospital surgical units from 1st January 2018 to 31st December 2019. In this study total of 5079 patients were included who were admitted through emergency and surgical outpatient department. They were operated in emergency and elective theatres in all three surgical departments of Abbasi Shaheed Hospital. Data was collected on pre-designed performa from emergency and elective theatre, wards, High-dependency unit and Intensive care unit maintained registers by staff.\u0000\u0000\u0000\u0000A total of 5079 cases were operated during January 2018 to December 2019. Among all the age ranges 1282 belongs to the age range of 21-30 years. Amongst which 59.6% were males. The most common diagnosis made in elective patients was chronic calculous cholecystitis (25.8%) and an abscess in emergency (39.4%). The most common procedure performed in elective surgeries was combined laparoscopic and open cholecystectomy (26.8%) and incision and drainage in the emergency (39.4%). Elective surgeries were mainly performed by Associate Professors (28.7). While, emergency surgeries were mainly performed by post-graduate trainees (70.2%). Surgical unit II has performed most surgeries (39.5%). Elective procedure constitutes about (51.60%). Total 19 patients expired out of 350 patients who were shifted or admitted in surgical ICU and 12 patients got expired in all three wards. \u0000\u0000\u0000\u0000We have higher number of elective surgeries as compared to the emergency surgeries. Consultants have performed most of the elective surgeries. Emergency surgeries mostly by residents and senior registrars. We have zero mortalities in our elective surgeries in comparison with emergency surgeries. We call attention to conduct continuous audits at our hospitals and all levels of health care and demand from higher authorized personals to incorporate audit awareness our teaching. Along with it, proper database should be installed with updated records maintenance to improve the lack of health care. \u0000","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89026341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leukostasis Due to Acute Myeloid Leukaemia with Monocytic Differentiation that Resolved after Leukapheresis","authors":"Tom L Enright, Anthony H Bui, William N Rose","doi":"10.25259/ijrsms-2022-2-6","DOIUrl":"https://doi.org/10.25259/ijrsms-2022-2-6","url":null,"abstract":"Even though the stakes of leukostasis are high, the data regarding the efficacy of leukapheresis for leukostasis is meagre. We report a patient with leukostasis due to acute myeloid leukaemia with monocytic differentiation who improved clinically after therapeutic leukapheresis, a rarely performed variation of therapeutic apheresis.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89767669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Covid-19: Potential relationship of anosmia and ageusia in swallowing rehabilitation","authors":"Katherine Peralta-Arancibia, Roberto Rojas-Segovia, Rocío Fuenzalida-Inostroza, L. Fuenzalida","doi":"10.32457/ijmss.v10i2.2218","DOIUrl":"https://doi.org/10.32457/ijmss.v10i2.2218","url":null,"abstract":"Anosmia and ageusia are prevalent symptoms in COVID-19 patients and can last for weeks. Sensory and olfactory functions perform an important role in swallowing. This article proposes the possible negative effect of the symptoms of anosmia and ageusia in the swallowing rehabilitation of dysphagia oropharyngeal and post-intubation in patients with COVID-19. It is important to consider that swallowing is a multisensory and pathological process, where taste and smell play a key role. In accordance with these factors, we propose future research incorporating objective evaluation methods of the affected senses in COVID-19 patients.","PeriodicalId":34302,"journal":{"name":"International Journal of Recent Surgical and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90363135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}