Hamdan Medical Journal最新文献

{"title":"Pulmonary mucormycosis: An anaesthesiologist's perspective","authors":"Ankit Gupta, A. Deshmukh, D. Koli, Hemant H. Mehta","doi":"10.4103/hmj.hmj_26_22","DOIUrl":"https://doi.org/10.4103/hmj.hmj_26_22","url":null,"abstract":"Introduction: As a frontline warrior, every anesthesiologist is fighting the coronavirus 2019 (COVID-19) pandemic to save lives, but at the same time, post-COVID sepsis has emerged as a serious challenge opening a new battlefield for corona warriors. In recent times, mucormycosis, a rare opportunistic fungal infection, has emerged as a serious and life-threatening disease that is spreading rapidly, leading to tissue infarction and necrosis in post-COVID patients; hence, quick recognition of this potentially lethal disease and early treatment is of paramount importance in reducing the mortality rate. Methods: The aim of this review article was to summarise the literature on anesthestic management of pulmonary mucormycosis (PM) patients undergoing thoracotomy surgery. Searches had been conducted in Google Scholar, Wiley online library, National Library of Medicine, PubMed, Scopus, Excerpta Medica Database and Cochrane Library using the following keywords: lung, mucormycosis, anaesthesia, presurgical, intraoperative, postsurgical and their permutations. Results: The true frequency of mucormycosis in India is still unknown; however, it is found to be consequentially more than in Western nations. PM has a high mortality rate, which is attributable in part to its locally aggressive nature and in part to the underlying risk factors; however, this rate has improved over time due to advancements in diagnostic techniques. Conclusion: Management of PM must be approached with a multifaceted, assertive plan. Early identification of infection, reversal of the prevailing risk factors, surgical elimination of contaminated tissue and medical management by antimycotic agents are the four critical steps in the management of mucormycosis. The key to a successful operation was a thorough pre-operative assessment, proper pre-operative preparation and much clinical surgical expertise.","PeriodicalId":34280,"journal":{"name":"Hamdan Medical Journal","volume":"15 1","pages":"59 - 65"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46885077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Audit of prostatic diseases diagnosed from Tru-Cut biopsies in Nnamdi Azikiwe University Teaching Hospital, Nnewi, using the P63 immunohistochemical marker","authors":"K. Madubuike, C. Ndukwe, M. Chiemeka, I. Ezejiofor, C. Ogbu, I. Onyiaorah, S. Nwosu","doi":"10.4103/hmj.hmj_72_21","DOIUrl":"https://doi.org/10.4103/hmj.hmj_72_21","url":null,"abstract":"Background: There is growing literature on the burden of prostatic lesions: both benign and malignant among men of West African ancestry. There are also some studies on the prostate in Anambra State and South-East Nigeria, but these are mainly on patterns and prevalence, without the use of immunohistochemistry. Aims and Objectives: The aim of this study is to determine the histological pattern of prostatic diseases diagnosed from Tru-Cut biopsies in Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, South-East Nigeria, using the p63 immunohistochemical marker. This will be a pioneer study in both the state and the geopolitical zone. Materials and Methods: This is a 2-year (January 2019 to December 2020) retrospective study of the immunohistochemical expression of p63 on the haematoxylin and eosin-diagnosed Tru-Cut biopsies of the prostate in the archives of the histopathology laboratory in NAUTH, Nnewi. A Purposive sampling method was used with a sample size of 151. Sections were made from the blocks, reviewed and stained using the p63 immunohistochemical marker. Results: There were 191 cases of prostate diseases histologically diagnosed, of which 151 met the inclusion criteria for the study. Of the 151 cases, 97 (64.2%) were diagnosed as benign and 54 (35.8%) were diagnosed as malignant. Following p63 immunohistochemistry, 97 cases were accurately diagnosed as benign and 54 cases accurately diagnosed as malignant with no misdiagnoses. The age of the patients ranged from 50 years to 90 years; however, the predominant population was in the sixth decade (31.8%) and seventh decade (35.1%), with a mean age of 75.3 years. There is no significant difference noted in the mean age of the non-neoplastic and neoplastic groups. Conclusion: This study shows that morphology alone is sufficient for the diagnosis of both Benign and prostatic lesions, as shown by the accuracy level (100%) in the haematoxylin and Eosin results. This is particularly important in resource-poor settings such as ours.","PeriodicalId":34280,"journal":{"name":"Hamdan Medical Journal","volume":"15 1","pages":"78 - 82"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43323679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contraception knowledge and practices among women in Peshawar","authors":"S. Salman, M. Rafiq","doi":"10.4103/hmj.hmj_8_22","DOIUrl":"https://doi.org/10.4103/hmj.hmj_8_22","url":null,"abstract":"Background: Contraception is an integral component for addressing the population emergency faced by resource deprived third-world countries like Pakistan but studies in this regard are lacking. Aims and Objectives: This study was conducted to assess the knowledge and practice of contraception among women in Peshawar. Materials and Methods: This cross-sectional prospective observational study was carried out from March 2020 to November 2021. All women of reproductive age were included in the study. Biodata, socio-economic status (SES), reproductive data, knowledge and practice of contraception were collected from a total of 1260 women during the study period. Results: One thousand two hundred and sixty females of reproductive age visiting the hospital were studied. Regarding reproductive health and contraception 431 (34.2%) had no knowledge and 415 (32.9%) had wrong information. Only 387 (30.7%) patients had correct information about fertility window, 447 (35.5%) had erroneous knowledge about it and 426 (33.8%) were completely uninformed about it. 609 (48.3%) patients were of low SES. 617 (49%) patients were motivated for contraception while 643 (51%) rejected it. 377 (29.9%) patients used no method for contraception, 398 (31.6%) used injectables while the remaining methods included; 225 (17.9%) implants, 68 (5.4%) natural withdrawal and 67 (5.3%) intrauterine contraceptive device. Conclusions: The study population lacked or had inadequate knowledge about reproductive health and contraception. Further, studies should be carried out for a wider understanding of the lack of contraceptive knowledge and practices to control the ballooning population growth and the lack of reproductive and contraceptive health services and practices.","PeriodicalId":34280,"journal":{"name":"Hamdan Medical Journal","volume":"15 1","pages":"97 - 100"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47242790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary colonic liposarcoma presenting as intussusception: A case report from the Kashmir valley","authors":"Yaqoob Hassan, A. Rather, Z. Akhtar","doi":"10.4103/hmj.hmj_76_21","DOIUrl":"https://doi.org/10.4103/hmj.hmj_76_21","url":null,"abstract":"Rationale: Soft tissue sarcoma (STS) arises from mesenchymal tissue and can occur at any anatomic site and age. These tumors can originate from skeletal muscle, adipose tissue, vascular tissues, or connective tissues. Liposarcoma (LPS) is the most frequent type of sarcoma and is commonly found in the retroperitoneal region. Patient Concerns: A case of colonic liposarcoma in a young female patient presented with sub-acute intestinal obstruction due to intussusception. The patient was only 17-years-old, much younger than the average age of occurrence, and thus represents the first case report of primary colonic liposarcoma in this age group. Diagnosis: The patient was resuscitated and subjected to standard investigations. An ultrasonography abdomen/ pelvis revealed colo-colic intussusception and CECT abdomen showed evidence of an enhancing mass within the lumen of the transverse colon. Interventions: The patient was subjected to exploratory laparotomy with segmental colonic resection and primary colo-colic anastomosis. Outcomes: The histopathology and immunohistochemistry revealed the morphology of high grade colonic liposarcoma. The patient is doing well eight months after surgery and is being monitored on a regular basis. Lessons: The primary gastrointestinal liposarcoma tumors are uncommon and colonic variants are extremely rare, especially in the second decade of life, and limited to case reports which can be counted on fingertips. Surgical resection with negative margins is the only curative treatment.","PeriodicalId":34280,"journal":{"name":"Hamdan Medical Journal","volume":"15 1","pages":"104 - 107"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48132074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ryles tube-guided difficult nasal intubation","authors":"K. Bineetha, D. Koli, Tapas Mandal, Hemant H. Mehta","doi":"10.4103/hmj.hmj_23_22","DOIUrl":"https://doi.org/10.4103/hmj.hmj_23_22","url":null,"abstract":"Rationale: Nasal intubation is an inevitable procedure in head and neck and oral cavity surgeries. Most of these patients usually present with distorted oral and nasal anatomy. Patient Concerns: The distorted anatomy in these patients makes their airway difficult and there are high chances of nasal bleed while securing the airway nasally. Diagnosis: Ryle's tube guided nasal intubation in a patient with temporomandibular joint derangement posted for bilateral temporomandibular joint arthrocentesis. Interventions: After induction of anaesthesia, we faced difficulty in passing North Pole tube via nasal passage, hence we rail roaded the North Pole tube over a Ryle's tube and successfully secured the airway. Outcomes: This innovative method helped us to secure the airway in this patient. Lessons: This simple technique of using a Ryle's tube as an aid for nasal intubation provides an alternate technique for difficult nasal intubation. Although it may not be the first choice for nasal intubation, this technique can be used as an alternative method in case, the tube could not be negotiated through the nasal passage.","PeriodicalId":34280,"journal":{"name":"Hamdan Medical Journal","volume":"15 1","pages":"108 - 111"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42629246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pseudoeosinophilia on automated analyser (Sysmex XN-1000) a guide to malaria detection - An incidental finding","authors":"M. Momin, Rahul Singh","doi":"10.4103/hmj.hmj_67_21","DOIUrl":"https://doi.org/10.4103/hmj.hmj_67_21","url":null,"abstract":"Rationale: Malaria is a protozoan disease which has a worldwide distribution in tropical and subtropical regions. The peripheral blood smear examination is a gold standard and an immunochromatographic rapid diagnostic test is an adjuvant diagnostic tool for the detection of malaria. For the past two decades, the utility of automated blood cell counters for the detection of malarial infection is growing in the presumptive diagnosis of malaria in developing countries. Patient Concerns: Here, we report a case in which a young male came for surgical evaluation for inguinal hernia surgery. On routine haemogram evaluation, malaria was suspected with the help of flow cytometry based haematology analyser (Sysmex XN 1000) generated histogram showing erroneously high eosinophil count (pseudoeosinophilia) and atypical white blood cell scattergram. Diagnosis: Peripheral smear and malarial antigen examinations confirmed Plasmodium vivax species. Outcomes: Patient was treated with antimalarial medications and elective surgery to repair inguinal hernia was planned after 10 days. Lessons: Here, we hope to increase the awareness of laboratory physicians to explore the possibilities of diagnosing malaria through hints provided by automated haematology analyser generated histograms.","PeriodicalId":34280,"journal":{"name":"Hamdan Medical Journal","volume":"15 1","pages":"101 - 103"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41339993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haematology reference range evaluation for novel research parameters on the complete blood count analyzer sysmex XN-1000","authors":"S. Rahar, Vijay Kumar, S. Rao, D. Gupta","doi":"10.4103/hmj.hmj_81_21","DOIUrl":"https://doi.org/10.4103/hmj.hmj_81_21","url":null,"abstract":"Background: In the field of haematology, there has been a consistent advancement in technology of the complete blood count (CBC) analyzers and hence, there has been an increase in the number of novel parameters that can be measured on these analysers. To put these newer parameters into routine clinical practice, it is essential to evaluate the reference ranges. Aims and Objective: To evaluate the reference intervals (RI) of the parameters which are calculated by Sysmex XN-1000, especially the newer research parameters. Materials and Methods: Blood samples from 150 clinically asymptomatic and apparently healthy individuals were assessed in the study and reference ranges for the same were evaluated on Sysmex XN-1000 CBC analyzer. Appropriate statistical tests were applied for the same. Results: The RIs of CBC parameters were evaluated in 123 adults (65 males and 58 females). Significant gender-dependent differences were found in red blood cells count, packed cell volume, haemoglobin (Hb), platelets and also in reticulocyte Hb and platelet-crit among the newer parameters. The other CBC reference ranges were also assessed from the remaining data. Conclusion: The present study, highlights the significance of different CBC parameters with special emphasis on newer research parameters. Although, the results of the current study are comparable with previous studies; further studies with larger sample sizes are needed for validation purposes in addition to the regional variation pertaining to these parameters.","PeriodicalId":34280,"journal":{"name":"Hamdan Medical Journal","volume":"15 1","pages":"83 - 88"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70737199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of sarcoidosis cases in the last decade: Is there a seasonal difference?","authors":"N. Özçelik, İlknur Koç, I. Aksoy, Funda Öztuna, Y. Bülbül, T. Özlü","doi":"10.4103/hmj.hmj_1_22","DOIUrl":"https://doi.org/10.4103/hmj.hmj_1_22","url":null,"abstract":"Background: The sarcoidosis cases were emphasized to differ seasonally in previous studies. In particular, the seasonal distribution of Lofgren syndrome and sarcoidosis arthritis cases has been reported to vary. Aims and Objectives: In this study, the seasonal variability of sarcoidosis cases defined in the literature was investigated among the patients who applied to our outpatient clinic. Materials and Methods: The data of 582 patients referred to our outpatient clinic and had a preliminary diagnosis of sarcoidosis between January 2010 and March 2020 were evaluated retrospectively. Demographic information, admission dates to the hospital, diagnostic methods, organ involvement, and seasonal characteristics were determined and analyzed. Results: Of the 582 patients evaluated in the study, 359 had the diagnosis of sarcoidosis. The mean age of our patients was 50 years; 96 (26,7 %) were male, and 263 (73,3 %) were female. The number of patients diagnosed histopathologically was 338 (94,2 %), and the most common extrapulmonary involvement was skin involvement with 37 cases. In the last decade, a significant number of patients (134 (37.3%) cases) were referred to the physician during the spring. Conclusion: Sarcoidosis is a multisystem disease with unknown etiology. In our study, similar to other studies, there was an increase in the symptoms during spring. Therefore, sarcoidosis should be kept in mind in patients with symptoms such as cough and shortness of breath accompanied by skin findings during the spring months. However, the data to explain this condition are not sufficient. Therefore, prospective studies are needed to explain the seasonal relationship with the pathophysiology of sarcoidosis.","PeriodicalId":34280,"journal":{"name":"Hamdan Medical Journal","volume":"15 1","pages":"89 - 92"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48025718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bezoar: An unusual cause of acute surgical abdomen","authors":"M. Al-Mendalawi","doi":"10.4103/hmj.hmj_14_22","DOIUrl":"https://doi.org/10.4103/hmj.hmj_14_22","url":null,"abstract":"","PeriodicalId":34280,"journal":{"name":"Hamdan Medical Journal","volume":"15 1","pages":"112 - 112"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48312308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiplanar imaging in a familial case of cleidocranial dysplasia and various orthodontic-surgical protocols approved for its treatment","authors":"S. Buch, R. Castelino, S. Babu, M. Baba","doi":"10.4103/hmj.hmj_61_21","DOIUrl":"https://doi.org/10.4103/hmj.hmj_61_21","url":null,"abstract":"Introduction: Cleidocranial dysplasia (CCD) is a rare autosomal-dominant disorder that results in defective ossification. The gene responsible for pathogenesis has been mapped to the short arm of chromosome 6p21 core-binding factor alpha-1 or runt-related transcription factor-2. The condition being a complex congenital disorder with numerous skeletal and dental anomalies, its management depends considerably on the patient's ambitions, age, economic status and permanent dentition status, endodontic and periodontal health. Case Report: A 17-year-old female reported with complaint of misaligned teeth and desired orthodontic treatment. The patient had been diagnosed with CCD during childhood but, seemingly, with no previous management. Family wise patient's mother presented with features of CCD but no previous health records. A familial case report of CCD is presented with a brief explanation of various orthodontic-surgical methods carried out for its treatment Conclusion: CCD is a rare disorder, with no universally acknowledged treatment plan; hence, it is appropriate to involve a multidisciplinary team for its management.","PeriodicalId":34280,"journal":{"name":"Hamdan Medical Journal","volume":"15 1","pages":"50 - 52"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41589435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}