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Advances in Clinical Neuroscience Rehabilitation最新文献

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Reanimating hand function after spinal cord injury using nerve transfer surgery 神经移植手术恢复脊髓损伤后的手部功能
Advances in Clinical Neuroscience Rehabilitation Pub Date : 2020-03-01 DOI: 10.47795/CQZF2655
M. Galea, A. Messina, B. Hill, C. Cooper, Jodie Hahn, Natasha van Zyl
{"title":"Reanimating hand function after spinal cord injury using nerve transfer surgery","authors":"M. Galea, A. Messina, B. Hill, C. Cooper, Jodie Hahn, Natasha van Zyl","doi":"10.47795/CQZF2655","DOIUrl":"https://doi.org/10.47795/CQZF2655","url":null,"abstract":"Loss of arm and hand function is a devastating consequence of cervical spinal cord injury. Tendon transfer surgery has traditionally been used to restore key functions including elbow extension, wrist extension and grasp and pinch. The more recent development of nerve transfer surgery enables direct restoration of voluntary control of these functions. While both types of surgery are safe and effective, nerve transfer surgery results in a more open, flexible and natural hand, with more subtle control for a range of activities of daily living.","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41552933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep Drivers 睡眠的司机
Advances in Clinical Neuroscience Rehabilitation Pub Date : 2020-03-01 DOI: 10.47795/opws3033
Clara Bolton, K. Anderson
{"title":"Sleep Drivers","authors":"Clara Bolton, K. Anderson","doi":"10.47795/opws3033","DOIUrl":"https://doi.org/10.47795/opws3033","url":null,"abstract":"Driving while sleepy can have devastating consequences, but it is an under-recognised problem often associated with behavioural factors, medical conditions or medications. All drivers have a responsibility not to drive if sleepy and there are DVLA regulations restricting driving for patients with certain sleep disorders who are at risk of excessive sleepiness at the wheel. However, sleepiness can be difficult for patient and doctor to assess and guidelines open to interpretation. As doctors it is important we give consistent and reliable advice to patients who may be at risk when driving. This review suggests how to assess driving risk, educate patients about risk reduction, and clarifies DVLA guidelines in this area.","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42603760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The fatal illness of Oscar Wilde 奥斯卡·王尔德的绝症
Advances in Clinical Neuroscience Rehabilitation Pub Date : 2020-02-03 DOI: 10.47795/yffo2946
J. Pearce
{"title":"The fatal illness of Oscar Wilde","authors":"J. Pearce","doi":"10.47795/yffo2946","DOIUrl":"https://doi.org/10.47795/yffo2946","url":null,"abstract":"The literary genius of Oscar Wilde has been sullied and besmirched by his infamous entanglement with Lord Alfred Douglas for “gross indecency” leading to his subsequent imprisonment for two years. After release he developed what was certified as “cerebral meningitis” in November 1900, from which he died. The much disputed cause is discussed. The claims for neurosyphilis are wholly inadequate; a chronic middle ear infection with cholesteatoma and intracranial suppuration is here suggested as the basis of his fatal illness. Had he lived in the 21st century Oscar Wilde would not have been so cruelly punished, may have received effective treatment, and thus been spared to provide much more of his wit and elegant plays, stories and poetry.","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81377460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cerebral malaria and the story of Quinine and the Fever Trees 脑疟疾和奎宁和发烧树的故事
Advances in Clinical Neuroscience Rehabilitation Pub Date : 2020-02-03 DOI: 10.47795/zikj9076
J. Pearce
{"title":"Cerebral malaria and the story of Quinine and the Fever Trees","authors":"J. Pearce","doi":"10.47795/zikj9076","DOIUrl":"https://doi.org/10.47795/zikj9076","url":null,"abstract":"Cinchona bark was first recorded as a cure for malaria by the Spanish in Peru around 1630. A Spanish missionary allegedly learned of the treatment from the Indian natives. Cerebral malaria caused by Plasmodium falciparum is life threatening and one of the commonest encephalopathies in the world. Quinine was the first effective treatment, discovered in the bark of quina-quina, cinchona, ‘the fever tree’ in Peru in 1633. Many tales – many fanciful – relate to its early use. Foremost of the discoverers in 1735 was a group of French scientists in an expedition to Peru directed by the Parisian Academie Royale des Sciences. It was then widely exported and employed in Spain, Italy and Britain to become the standard treatment.","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72549601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arnold's Nerve 阿诺德的神经
Advances in Clinical Neuroscience Rehabilitation Pub Date : 2020-02-01 DOI: 10.47795/rump8417
Jms Pearce
{"title":"Arnold's Nerve","authors":"Jms Pearce","doi":"10.47795/rump8417","DOIUrl":"https://doi.org/10.47795/rump8417","url":null,"abstract":"","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72797290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Pellagra: 4 D's and 8 Points. 糙皮病4 个 D 和 8 个点
Advances in Clinical Neuroscience Rehabilitation Pub Date : 2020-01-01 DOI: 10.47795/FBFD9966
Adrian Williams
{"title":"Pellagra: 4 D's and 8 Points.","authors":"Adrian Williams","doi":"10.47795/FBFD9966","DOIUrl":"10.47795/FBFD9966","url":null,"abstract":"<p><p>Pellagra has largely been forgotten. This is unfortunate as important lessons are to be learnt for the diseases and social consequences of poverty (and of affluence) that often involve dietary nicotinamide and nicotinamide adenine dinucleotide (NAD) homeostasis. NAD disruption can occur not only from poor diet but from increased consumption of NAD from genotoxic and other stresses. High doses of nicotinamide lead to inhibition of NAD-consuming enzymes and excessive induction of nicotinamide-n-methyl transferase (NNMT) with consequent effects on the methylome giving a mechanism for a new hypervitaminosis-B3.</p>","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"20 1","pages":"fbfd9966"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138831925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pourfour Du Petit and the cervical sympathetic nerves 第四杜佩蒂和颈交感神经
Advances in Clinical Neuroscience Rehabilitation Pub Date : 2020-01-01 DOI: 10.47795/layq8071
Pearce Jms
{"title":"Pourfour Du Petit and the cervical sympathetic nerves","authors":"Pearce Jms","doi":"10.47795/layq8071","DOIUrl":"https://doi.org/10.47795/layq8071","url":null,"abstract":"François Pourfour du Petit (1664-1741) was a Parisian experimental Neuroanatomist, and Ophthalmologist. Based on his extensive experiences of brain and spinal injuries as a military doctor in the armies of Louis XIV he performed many animal experiments that demonstrated the anatomy and functional significance of the cervical sympathetic nerves, correcting previous errors of Thomas Willis and Raymond Vieussens. He long predated the descriptions of Horner’s syndrome (1869) when he showed that interruption of sympathetic pathways inactivated both the dilator muscle and produces miosis, and the superior tarsal muscle, which produces ptosis and enophthalmos. This was later elaborated by Hare, Weir Mitchell and Claude Bernard.","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74242967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An expert opinion: Optimisation of pharmacological management of multiple sclerosis related spasticity 专家意见:优化多发性硬化症相关痉挛的药物管理
Advances in Clinical Neuroscience Rehabilitation Pub Date : 2019-10-01 DOI: 10.47795/kaib7737
R. Farrell, D. Baker
{"title":"An expert opinion: Optimisation of pharmacological management of multiple sclerosis related spasticity","authors":"R. Farrell, D. Baker","doi":"10.47795/kaib7737","DOIUrl":"https://doi.org/10.47795/kaib7737","url":null,"abstract":"Spasticity is a frequent symptom in people with Multiple Sclerosis. Whilst many respond to first-line therapies it is estimated that 30-40% will have suboptimal treatment response requiring more specialised management. Such strategies include combination of oral medications, botulinum toxin, nabiximols and consideration of intrathecal therapies; baclofen or phenol. Early expert intervention as outlined in this review can have a positive impact on functional ability and quality of life for people with MS.","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87018921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Choked disc, optic neuritis, and papilloedema 椎间盘阻塞，视神经炎，乳头状水肿
Advances in Clinical Neuroscience Rehabilitation Pub Date : 2019-07-30 DOI: 10.47795/ysmn1469
Jms Pearce
{"title":"Choked disc, optic neuritis, and papilloedema","authors":"Jms Pearce","doi":"10.47795/ysmn1469","DOIUrl":"https://doi.org/10.47795/ysmn1469","url":null,"abstract":"Before the invention of the ophthalmoscope in 1851, doctors were neither able to recognise papilloedema nor to diagnose accurately intracranial hypertension, malignant hypertension and inflammatory and systemic disorders affecting the optic fundus. This paper seeks to uncover early descriptions and experiments that tried to unravel the causes of the swollen optic disc, its mechanism and its clinical significance. Papilloedema is a purely descriptive name that requires the underlying cause to be specified.","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88128229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Myotonic (Holmes Adie) pupil 肌强直瞳孔
Advances in Clinical Neuroscience Rehabilitation Pub Date : 2019-05-29 DOI: 10.47795/mxli5114
J. Pearce
{"title":"The Myotonic (Holmes Adie) pupil","authors":"J. Pearce","doi":"10.47795/mxli5114","DOIUrl":"https://doi.org/10.47795/mxli5114","url":null,"abstract":"","PeriodicalId":34274,"journal":{"name":"Advances in Clinical Neuroscience Rehabilitation","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83289950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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