B. Yarchuk, S. Bilyk, R. Tyrsin, O. Dovgal, P. Shulga, Y. Tyrsina, T. Tsarenko, L. Kornienko, V. Ukhovskyi
{"title":"Epizootological features of cattle leptospirosis in the Vinnitsa region of Ukraine","authors":"B. Yarchuk, S. Bilyk, R. Tyrsin, O. Dovgal, P. Shulga, Y. Tyrsina, T. Tsarenko, L. Kornienko, V. Ukhovskyi","doi":"10.33245/2310-4902-2019-149-1-41-48","DOIUrl":"https://doi.org/10.33245/2310-4902-2019-149-1-41-48","url":null,"abstract":"Leptospirosis is a common worldwide zoonotic infection, is an important livestock problem throughout Ukraine. The peculiarities of leptospirosis are the presence of more than 250 serological groups of the pathogen, which significantly influences the choice of strategy for prevention and control of this disease.\u0000The article presents data on the epizootic situation, the epizootological features of leptospirosis and the etiological structure of leptospiras in cattle in Vinnitsa region (1994-2015) and, in particular, in the farms of the Khmelnitsky district (2006-2012). The epizootic situation with leptospirosis of cattle in Vinnitsa region and the farms of Khmelnytsky district is characterized by certain fluctuations in the number of infections points and sick animals, with relative stability. Tottaly 247 cattle farms infections of leptospirosis were identified in the region during 21 years.\u0000The materials for the research were the data of veterinary records and reports of farms and state veterinary medicine establishments of Vinnitsa region, the results of laboratory tests of blood serum from cattle from suspicious farms, the results of the analysis of health and preventive measures in suspicious farms.\u0000The main leptospira serogroups that affect cattle in Vinnytsa region and directly in the Khmelnitsky region were Hebdomadis, Sejroe, Icterohaemorrhagiae, Grippotyphosa, Pomona, registered from 43 to 86.3% of mixed reactions.\u0000In Khmelnytsky district in 2006-2012, 7 infected farms were registered, 739 animals got sick. It was established that the epizootic situation in the farms depended on the observance of preventive and sanitary measures and the timely introduction of recovery plans. It has been proved that the integrated use of veterinary, sanitary and economic measures is an effective means of eliminating and preventing cattle leptospirosis in livestock farms. The complex of measures should include timely serological analisis of cattle on leptospirosis, adherence to quarantine during importation of animals to the herd, sanitary and preventive measures of exploitation of animals, vaccination of cattle against leptospirosis, taking into account the etiological structure of the disease.\u0000Key words: leptospira, leptospirosis, cattle, microscopic agglutination test (MAT), leptospira serological groups, epizootic situation.","PeriodicalId":34230,"journal":{"name":"Naukovii visnik veterinarnoyi meditsini","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69582947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative morphofunctional and species-specific vascularization features of of the knee capsule of some mammals","authors":"V. Novak, O. Bevz, A. P. Melnichenko","doi":"10.33245/2310-4902-2019-149-1-57-65","DOIUrl":"https://doi.org/10.33245/2310-4902-2019-149-1-57-65","url":null,"abstract":"The metabolic, reparative and plastic properties, as well as the functional activity of the multiorgan synovial environment of the knee joint, are organically and functionally related to their morphology and blood supply. The aim of our research was to determine the general biological and specific features of the structural organization and vascularization of the knee joint capsule in animals with different supports, locomotion and body weight. A complex of morphological research methods is used in this work: anatomical, histological, neurohistological. Used neurohistological method of impregnation in its own algorithm. The structural organization of synovial and fibrous capsule, histotopography of intraorganic vessels was studied on 43 objects of various groups of animals. The selection of animals was carried out according to the type of limb specialization to the substrate. Animals were taking into account the ecology, types of support, the nature of locomotion and the speed of movement – phalanoid animals – a domestic horse, a domestic bull and a finger animal – a domestic dog and a domestic cat. As a result of the complex comparative-morphological study the general patterns of the structural organization of the articular capsule, the general-biological and species-specific features of the angioarchitectonics and angiotopography were established. The zones of the most intense intraorganic vascularization and the topography of the vascular fields and glomeruli of the articular capsule are shown. The zones of intensive vascularization are localized: in the domestic bull – in the medial, dorsal, lateral parts, vascular glomeruli – in the lateral; in the domestic horse – in all parts of the capsule, vascular glomeruli – in the plantar area; in the domestic dog – in the medial, dorsal, plantar parts, vascular glomeruli – in the plantar area; in a domestic cat, the same type of angioarchitectonics is observed, the vascular fields and glomeruli are absent. The more intense angioarhitectonics in the capsule of the knee joint in phalanoid animals (horse, cattle) than in the finger (dog, cat) possibly due to the different nature of the support and type of locomotion, is determined.\u0000Key words: vascular fields, vascular glomeruli, angioarchitectonics, knee joint, joint capsule, domestic horse, domestic bull, domestic dog, domestic cat.","PeriodicalId":34230,"journal":{"name":"Naukovii visnik veterinarnoyi meditsini","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49197543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"State of protein and mineral exchange in broiler-chickens for the use of Zinc and Mangane chelates","authors":"V. Sakara, A. Melnyk, F. Markhenkov","doi":"10.33245/2310-4902-2019-149-1-85-94","DOIUrl":"https://doi.org/10.33245/2310-4902-2019-149-1-85-94","url":null,"abstract":"The results of the application of a complex of Zinc and Manganese chelates to protein, macro- and micro-mineral exchanges in the body of broiler chickens of the Cobb 500 cross-breed are presented. The administration of Zn and Mn chelates in a dose of 0,2 ml/l for chicken broilers of 23 days of age (1st experimental group) during 14 days influenced the increase in the total protein content to 35,3±0,8 g/l, which is 8 % higher compared with the control – 32,5±0,7 g/l (p<0,01 ) The concentration of total Calcium in serum of broiler chickens 37-day-old (end of trial) was higher in the first experimental group by 7,3 % (2,05±0,06 mmol/l) compared to control – 1,9±0,03 mmol/l. In the second group, where chelates were administered in a dose of 0,4 ml/l of water, the Calcium content was 2,0±0,02 mmol/l, which is 5 % more than the control group. The two-week application of Zn and Mn chelates also led to an increase in the level of inorganic Phosphorus in the serum of the first group to 2,6±0,12 mmol/l (+ 11,5 %) compared with the control group. After administration of chelates Zn and Mn at doses of 0,2 ml/l water, the Zinc content was higher by 4,3% (23,5±0,2 μmol/l) compared to control – 22,5±0,34 μmol/l (p<0,01). In the second group, where the dose of chelates was 0,4 ml/l, the concentration of Zinc was 23,6±0,16 μmol/l, which is more than 4,6 % for control (p<0,01). At the end of the study, the content of Manganese in serum of broiler chickens in the first group was 1,9±0,07 μmol/l (p<0,05), which is 10,4% higher compared with the control – 1,7±0,06 μmol/l (3rd sampling). The level of this element in the second group was 2,0±0,08 μmol/l (p<0,01), which is higher by 16,7 % relative to the control. At the end of the experiment, the coupon concentration in the first and second experimental groups was 12,6 and 9,3 % higher, compared with control, 7,0±0,37 μmol/l. In turn, the serum Ferrum content of the first group was greater by 9,3 % (19,3±0,69 μmol/l), and the second by 6,7 % (18,8±0,47 μmol/l) compared to the bird of the control group.\u0000Key words: chicken broilers, chelates, Zinc, Manganese, Cuprom, Ferrum, metabolism.","PeriodicalId":34230,"journal":{"name":"Naukovii visnik veterinarnoyi meditsini","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69583017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peculiarities of acute phase reaction and its correction in surgical pathology in pigs","authors":"V. Melnikov, M. Rublenko, V. Storozhuk, V. Dudka","doi":"10.33245/2310-4902-2019-149-1-111-118","DOIUrl":"https://doi.org/10.33245/2310-4902-2019-149-1-111-118","url":null,"abstract":"Surgical pathology in animals is quite broad and has various forms of manifestation. It covers various anatomic-topographic areas and organs, in particular in pigs quite often presented with abdominal pathology. There have been published reports of an incidence of hernias in 0.8-3.5% of the pig population, which is 50% of all surgical pathology of the whole animal species.\u0000In the group of clinically healthy pigs (n = 10), a significant level of anti-inflammatory IL-10 is noticeable. At the same time, rather high cytokine indices of the ratio of anti-inflammatory to proinflammatory cytokines in healthy animals – 13.9:\u00001 – 19.4: 1, with the index between the latter – 0.7: 1. That is, in general, IL-10, under physiological norms, exercises a powerful control over the phylogenic cytokine systems of the pig body.\u0000At the same time, animals with surgical pathology show a sharp increase in the levels of proinflammatory cytokines. For hernias accompanied by an adhesive-inflammatory aseptic process, serum TNF-α content is increased 4.9-fold and IL-1β is slightly less – only 2.1-fold, with a moderate increase in the concentration of 1.3-fold anti-inflammatory IL- 10. In this case, cytokine indices are significantly reduced, which indicates a decrease in the activity of antiflogogenic mechanisms.\u0000\u0000The dynamics of the development of purulent arthritis is characterized by a remarkable increase in blood levels of\u0000TNF-α – 18.3 times, and a moderate increase in the concentrations of IL-1 and IL-10. In this case, the cytokine index of\u0000IL-10: TNF-α acquired a critical value of 1.5: 1, and the number of the latter exceeded the level of IL-1β by more than\u00005 times. At the same time, elevation of IL-1β and IL-10 levels did not lead to a significant difference with the indigenous animals. Most likely, the powerful synthesis of TNF-α is associated with the appearance of a large number of cells of its producers in the area of destruction of the joints. In this case, insufficient increase in the level of IL-10 triggers the process of cascading production of inflammatory mediators and the development of systemic inflammatory syndrome.\u0000Fibrinogen, as one of the acute phase reaction proteins, fluctuates within 2–4 g / L by physiological norms. In the early postoperative period, its level increases significantly, however, the peaks of increasing plasma fibrinogen concentration in control animals are recorded on day 1 and day 7. By using the immune depot, on the contrary, it is dynamically normalized to the 7th day after the hernia. The dynamics of fibrinogen concentration with the use of thiotriazoline were somewhat different. It peaked after the first day and was 2.3 times higher than immuno depot injections. In the following, only after the 3rd day the level of fibrinogenemia began to normalize dynamically, which can be explained by the pronounced hepatoprotective effect of thiotriazoline with increased synthesis of fibrinogen by the liver.\u0000The level of haptoglobin, like f","PeriodicalId":34230,"journal":{"name":"Naukovii visnik veterinarnoyi meditsini","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69582925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influence of microbiological starter of filler of biofilter of \"Filtronorm D\" on stored of rainbow trout","authors":"N. Grynevych","doi":"10.33245/2310-4902-2019-149-1-15-21","DOIUrl":"https://doi.org/10.33245/2310-4902-2019-149-1-15-21","url":null,"abstract":"Creation in biofilters of favorable conditions for the existence of biocenoses secures RAS from the toxic effects of nitrites, which until recently did not attach great importance to toxicants for aquatic organisms. However, it has been found that they are very toxic to fish and aquatic invertebrates. The purpose of the work was to investigate the effect of microbiological starter of the \"Filtronorm-D\" biofilter filler on the behavior of adult rainbow trout during the launch of the biofilter.\u0000Investigation of the influence of the microbial starter of the filtrotorm-D biofilter filler on the behavior and clinical condition and the preservation of rainbow trout during the launch of the biofilter of the ultrasound has been studied.\u0000Evaluated the clinical signs of adult rainbow trout during the launch of the biofilter CWS for the use of polypropylene filler RK PLAST-control in it. According to the second variant, the clinical signs of adult rainbow trout were evaluated during the startup of the biofilter of the ultrasound scanner for the use of polypropylene filler RK PLAST in it and the addition of the microbiological starter of the biofilter \"Filtronorm-D\" – experiment. In the experimental group, the biofilter water was introduced by our microbiological starter, biofilter filler \"Filtronorm-D\", containing live cultures of nitrifying and denitrifying bacteria in the amount of 107 CFU/cm3.\u0000On the 10th day of the experiment, after the application of the microbiological starter of the biofilter filler \"Filtronorm-D\",\u0000approximately 5 % of the fish with the initial clinical signs of nitrite poisoning were detected. The fish for a long time stood motionless in the corners of the pool, they had the darkening of the body and the brown color of the gills. On the 15th day after the launch of the CWS and the use of \"Filtronorm-D\", changes in behavior were detected in most of the research objects, which may indicate an increase in the amount of nitrites in water and their effect on the body of trout. Approximately 25 % of fish for a long time stays motionless in the corners of the pool, the mobility of the whole fish has decreased, some individuals have risen to the surface of the water. Changes in pigmentation of the body were also found in approximately\u000010 % of the individuals. The body became darker, the fins were sealed, the gills got brown color. During this trial period, the mortality rate of the fish was 1,3 %. On the 20th day of the experiment, the signs of nitrite poisoning of fish became increasingly pronounced. Approximately 30 % of the fish showed the presence of darkening of the body and fins, the latter were sealed. In the same fish, the changed color of the gills was observed – from red to brown. In addition, during this period of research, the highest trout death was determined – 3,1 %, which is almost 2.4 times (p <0,05) higher than in the 15-day period. The period of ultrasound starting from the 20th to the 25th day was characterized by a decr","PeriodicalId":34230,"journal":{"name":"Naukovii visnik veterinarnoyi meditsini","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69582934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of the insemination of the mesophilic and psychrotrophic microflora of frozen fish","authors":"Z. Malimon, M. Kukhtyn, N. Grynevych, N. Mekh","doi":"10.33245/2310-4902-2019-149-1-22-29","DOIUrl":"https://doi.org/10.33245/2310-4902-2019-149-1-22-29","url":null,"abstract":"The article presents the results of research on the dehiscence of frozen fish with mesophilic and psychrotrophic microflora. Physico-chemical and organoleptic changes which appear in fish during refrigeration are connected with the life of the psychotropic group of microflora, which is more active than mesophilic. Fish are a nutrient medium for the development of microorganisms of all groups, due to its high nutritional and biological value, so the fish are perishable food products, the conditions and terms of their storage require appropriate temperature regimes to stop the development of microorganisms. The aim of the work was carrying out a comparative analysis of insemination of frozen fish with mesophilic and psychrotrophic microflora to make an amend to standards according to microbiological criteria.\u0000The microbial number in frozen fish samples was estimated with the temperature of (30 ± 1) ºC incubation of crops for 72 hours (mesophilic microflora) and incubation for 10 days (psychrotrophic microflora) with the temperature (6.5 ± 0.5) ºC.\u0000It was identified that there were taken the samples from frozen fish with a quantity of mesophilic bacteria to 102 CFU/g, 1.4-1.8 times (p <0.05) more psychotropic microorganisms. The researched samples with the number of mesophilic microorganisms from 103 to 104 CFU/g were contaminated with psychotropic microflora, which in 1.7-6.8 times (p <0.05) exceeded the content of the mesophilic microflora. With such amount of mesophilic microorganisms, on average of up to 25% of samples, this had a content of psychotrophs of more than 105 CFU/g of fish. According to the content of mesophilic bacteria the samples of frozen fish, which were mathed to a certain norm of 5 × 104 CFU/g, basically in the number of psychrotrophic microflora did not correspond to this indicator, and exceeded it 2 times or more.\u0000In the cold period of the year, 63.6 ± 2.1% of frozen fish samples were mesophilic bacteria containing less than 101 CFU/g. \u0000At the same time, samples with such content mesophilic bacteria in the warm period of the year was 9.0%, or 7.0 times\u0000(p <0.05) less. In addition, in the cold period of the year, only 9.0% of samples were detected, which, according to the content of mesophilic bacteria exceeded the maximum allowable level. At the same time, during the warm period, the number of samples with an excess of mesophilic bacteria content was 27.3 ± 0.3%. Practically the same pattern was observed regarding the insemination of the psychrotrophic microflora in these periods of the year, which was characterized by the fact that in the warm period of the year, frozen fish contains a large number of psychrotrophic microorganisms. Consequently, the results of studies on the amount of microflora in the warm period of the year established 3,0 times (p <0,05) more samples of frozen fish, which, according to the content of mesophilic bacteria, exceeded the maximum permissible level compared with the cold period of the year.\u0000It","PeriodicalId":34230,"journal":{"name":"Naukovii visnik veterinarnoyi meditsini","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46984099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"INTERNATIONAL AND NATIONAL LEGISLATION TO CONTROL MICTOXINS IN FOOD: REVIEW","authors":"O. Khitska, R. Gerard","doi":"10.33245/2310-4902-2019-149-1-30-40","DOIUrl":"https://doi.org/10.33245/2310-4902-2019-149-1-30-40","url":null,"abstract":"Today, the problem of monitoring mycotoxins has become global in connection with climate change, a violation of the ecological balance for the use of intensive technologies for processing crops, through air pollution and the accumulation of products of photochemical reactions (photooxidants), which leads to a decrease in plant resistance to phytopathogens.\u0000Every year, the problem of mycotoxicosis is exacerbated, as toxic fungi adapt quickly to new technologies and modern plant protection products. The increase in mycotoxins in foods also relates to the widespread use of nitrogen fertilizers and pesticides.\u0000Natural toxins create risks for the health of humans and animals, affect food security and nutrition, reducing people's access to healthy food. The World Health Organization is constantly appealing to national authorities to monitor and ensure that the levels of the most relevant natural toxins in foods are as low as possible and consistent with both national and international requirements.\u0000Ukraine's membership in the WTO, an association with the European Union, and the expansion of international trade require solutions to the issues of free movement of goods, safe and healthy food, and, accordingly, an adequate level of protection of life and health of people. One of the most important ways to solve them is to improve and harmonize national food legislation in line with international standards, including on the control of mycotoxins.\u0000The purpose of our work was to conduct an analysis of literary sources, international and national legislative acts on the control of mycotoxins in food products throughout the food chain.\u0000To prepare the publication, we have used literary sources on the subject of publication, as well as we have conducted a comparative analysis of national and international legislative acts regulating procedures and methods for controlling the residues of mycotoxins in food.\u0000An analysis of numerous sources has shown that the issue of monitoring mycotoxins in foods, improving laboratory control and risk-based approach to preventing foodborne mycotoxicosis worries scientists from different countries, including Ukrainian. The analysis of national legislation shows that national standards on maximum levels of pollutants have been revised in Ukraine and a number of standards have been harmonized for methods of monitoring the residues of mycotoxins in feed for productive animals, food products of animal and vegetable origin.\u0000Key words: mycotoxins, food chain, food, international law, national legislation, control, safety, risks.","PeriodicalId":34230,"journal":{"name":"Naukovii visnik veterinarnoyi meditsini","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69582941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Belko, M. Matsinovich, V. Petrov, A. A. Matsinovich
{"title":"THE EFFECTIVENESS OF A COMPREHENSIVE TREATMENT REGIMEN USING SODIUM THIOSULFATE WITH GASTROINTESTINAL DISEASES IN CALVES WITH INTOXICATION SYNDROME","authors":"A. Belko, M. Matsinovich, V. Petrov, A. A. Matsinovich","doi":"10.33245/2310-4902-2019-149-1-95-101","DOIUrl":"https://doi.org/10.33245/2310-4902-2019-149-1-95-101","url":null,"abstract":"The aim of the research was to study the dependence of the severity on the degree of endogenous intoxication and the effectiveness of complex treatment of calves using sodium thiosulfate-based drugs for gastrointestinal diseases. Studies were carried out under production conditions in cattle farms of the Vitebsk, Liozno and Gorodok districts. As preparations based on sodium thiosulfate, the veterinary drug \"Averon\" produced by LLC Belekotekhnika RB and the veterinary preparation Antitox manufactured by ImmCont GmbH, Germany, were used. These drugs as an antitoxic agent, were administered once a day, intravenously, slowly at a dose of 25 ml, until the clinical signs of the disease disappeared in addition to the basic treatment taken in the farms with gastrointestinal diseases.\u0000The data obtained as a result of the analysis of the literature and the conduct of our own research showed that in the pathogenesis of gastrointestinal diseases of the calves, the link to the pathogenesis, which significantly determines the severity of their course and prognosis, is endogenous intoxication. It was found that in patients with calves, the MW content was higher at the height of the disease – 1.75–2 times with moderate severity and 1.94 and 2.47 times with severe. Laboratory criteria were established for predicting the severity of dyspepsia and abomasoenteritis in calves of 14 to 30 days of age. So, at a level higher than 0,120 conv. units in 100% of such calves, dyspepsia or gastroenteritis proceeded in a severe (toxic) form. The significant direct correlations between the concentration of MWS and LPO products (r ≥ 0.650) revealed at the height of the disease indicate the significance of LPO as a source in the development of endotoxication in gastrointestinal diseases in calves. It has been established that the use of drugs with antitoxic action based on sodium thiosulphate in the complex therapy of calves of patients with dyspepsia and abomasoenteritis can reduce the severity and lethality of calves with dyspepsia by 5% to 10%.\u0000Key words: calves, blood, endogenous intoxication, abomazoenteritis, dyspepsia, therapeutic efficacy, treatment.","PeriodicalId":34230,"journal":{"name":"Naukovii visnik veterinarnoyi meditsini","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48286521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Nischemenko, V. Kaplunenko, V. Koziy, O. Poroshinska, L. Stovbetska, A. Yemelyanenko, O. Omelchuk
{"title":"The indexes of mineral exchange in laying hens under the influence of Selenium and Zinc nonoacquahelates and vitamin E","authors":"M. Nischemenko, V. Kaplunenko, V. Koziy, O. Poroshinska, L. Stovbetska, A. Yemelyanenko, O. Omelchuk","doi":"10.33245/2310-4902-2019-149-1-49-56","DOIUrl":"https://doi.org/10.33245/2310-4902-2019-149-1-49-56","url":null,"abstract":"The article presents the results of the study of the influence of nanoacquahelats of biogenic and biocidal metals Selenium and Zinc together with vitamin E, on the mineral metabolism indexes of hens of Loman Brown breed. It is known that the inflow of mineral elements such as Calcium and inorganic Phosphorus into the body and its proper usage is essential for the maintenance of egg productivity and egg quality. In this regard, it is promising to study the changes of the above-mentioned processes with the Selenium, Zinc and vitamin E nanoacqualates supplementation. It has been established that the feeding of Selenium and Zinc nanocarboxylic acids with vitamin E positively affects the exchange of Calcium and inorganic Phosphorus in the laying hens. In particular, the content of calcium in the serum of tested hens was significantly higher (17.3-26.7%), on the 60th and 90th days of the experiment, comparing with the control group. The level of inorganic phosphorus, on the 60th and 90th days of the experiment, also increased by 17.7% and 16.9%, respectively, in experimental group of layer hens compared to control one.\u0000It is known that macroelements Ca and inorganic Phosphorus are important components for the organism of animals and, especially, birds. These minerals have no nutritional value, are not used by the body as a source of energy, but their role as structural elements cannot be overestimated. Both Calcium and inorganic Phosphorus are part of almost all organs and tissues. The growth and development of the organism, as well as its productivity depends on the presence of these elements in the diet. In addition, Calcium and inorganic Phosphorus are actively involved in the regulation of a number of vital functions. In the birds, it is the synthesis of proteins and the intense formation of egg minerals. They are also necessary for the further formation of bone tissue of the embryo. Consequently, the presence of these minerals in the diet and in the body of layers hens, to a large extent determine their weight and quality of eggs.\u0000The obtained results show the use of nanoacquahelats of Selenium and Zinc together with vitamin E stimulate phosphorus-calcium metabolism and alkaline phosphatase activity due to their biophysical properties which are based on activation of many biochemical processes according to the effect of Borisevich-Kaplunenko-Kosinov.\u0000Key words: Calcium, Phosphorus, laying hens, Selenium, Zinc, vitamin E.","PeriodicalId":34230,"journal":{"name":"Naukovii visnik veterinarnoyi meditsini","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69583005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Feshchenko, O. Zghozinska, O. Dubova, T. Bakhur, V. Goncharenko, Yu. Stoliarova
{"title":"Comparative effectiveness of complex treatment schemes for rabbits with pasalurosis and psoroptosis","authors":"D. Feshchenko, O. Zghozinska, O. Dubova, T. Bakhur, V. Goncharenko, Yu. Stoliarova","doi":"10.33245/2310-4902-2019-149-1-66-74","DOIUrl":"https://doi.org/10.33245/2310-4902-2019-149-1-66-74","url":null,"abstract":"Psoroptosis and pasalurosis in rabbits for their maintenance in unsanitary conditions often becomes massive. To increase the effectiveness of treatment of rabbits it is expedient to use combined drugs based on active substances with different mechanisms of action on parasites. Rabbits of the first experimental group applied spray treatment with acaricidal properties of kerosene + glycerol (1:1) three times with an interval of 5 days. Spraying the inner surface of the ears was carried out after mechanical cleaning with gauze swabs soaked in iodine solution + glycerin (1:4). To destroy the helminths, brovadasol plus (5 g/10 kg body weight), orally with food, was administered once. For animals of the second experimental group, the \"brovermectin 2%\" helminthoacaricide was chosen, it was orally administered at a dose of 1 ml/50 kg body weight, divided into 5 days of regular use. Mechanical treatment of ear with chlorhexidine bigluconate was carried out analogously to rabbits of the first group twice a day for 10 days. On the day of treatment with the rabbits in the second group, Dexacel 0.2 % (KELAN.V., Belgium) was injected intramuscularly with a dose of 0.1/1 kg of body weight, in order to improve the general animal's stanchion.\u0000For combined infestations (scabies and nematodes) it is advisable to use preparations based on ivermectin (in our study, \"Brovermectin 2%\" at a dose of 1 ml/50 kg, which was divided into 5 parts and daily diluted one part in 1/2 of the daily water) In the case of the need to treat only psoroptosis, one can use a kerosene solution in glycerol (1:1) in the form of a spray.\u0000A prerequisite for the effective treatment of psoropathy is the regular mechanical cleaning of the affected ears from the purulent parasitic exudate or iodine solution + glycerol (1:4) or Chlorhexidine bigluconate 0,05%. It is appropriate to use \"Dexacel 02\" (one time, non-inflammatory y dose of 0.1/1 kg body weight) in order to improve the general animal's condition.\u0000The use of \"Brovadazole plus\" (once, with food, at a dose of 5 g/10 kg body weight) did not ensure 100% destruction of Passalurus ambiquus, but due to the short carencia period (only 7 days), if necessary, can be applied to fattening rabbits in the last 2 weeks before slaughter. In contrast to the period of carencia, \"Brovermectin 2%\" is at least 24 days.\u0000Key words: rabbit, psoroptosis, pasalurosis, brovermectin, acaricidal efficacy, Dexacel 02.","PeriodicalId":34230,"journal":{"name":"Naukovii visnik veterinarnoyi meditsini","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69583012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}