Quarterly of the Horizon of Medical Sciences最新文献_第2页

The Effects of High-intensity Interval Training and Probiotic Consumption on Interleukin-10 and Interferon-gamma Gene Expression of Gut Tissue in an Animal Model of Fatty Liver 高强度间歇训练和益生菌摄入对脂肪肝动物模型肠道组织白细胞介素-10和干扰素- γ基因表达的影响

Quarterly of the Horizon of Medical Sciences Pub Date : 2021-06-10 DOI: 10.32598/HMS.27.3.3067.2

Sharmin Rasheh, M. Ahmadi

{"title":"The Effects of High-intensity Interval Training and Probiotic Consumption on Interleukin-10 and Interferon-gamma Gene Expression of Gut Tissue in an Animal Model of Fatty Liver","authors":"Sharmin Rasheh, M. Ahmadi","doi":"10.32598/HMS.27.3.3067.2","DOIUrl":"https://doi.org/10.32598/HMS.27.3.3067.2","url":null,"abstract":"Aims: Non-Alcoholic Fatty Liver Disease (NAFLD) is the most common chronic liver disease, often reported in patients with inflammatory bowel disease. This study aimed to investigate the effects of High-Intensity Interval Training (HIIT) and probiotic use on the expression of interleukin-10 and interferon-gamma genes in intestinal tissue in an animal model of fatty liver. Methods & Materials: In this experimental study, 40 male Wistar rats (weighing 200-250 g) were selected. The study rats were randomly divided into 5 groups, including healthy control, fatty liver, fatty liver + HIIT, fatty liver + probiotic, and fatty liver + HIIT + Probiotics. Oral tetracycline was administered at a dose of 140 mg/kg of body weight (as a solution in 2 mL of water) for 7 days with fatty liver. HIIT was performed on tape 5 times a week for 5 weeks. The obtained data were analyzed using One-way Analysis of Variance (ANOVA) and Tukey post-hoc test at the significant level of P<0.05. Findings: The present research results suggested that the expression of interleukin-10 and interferon-gamma genes in the intestinal tissue of steatosis mice in the fatty liver group was significantly higher than in the healthy control group (P=0.001). HIIT and probiotic use significantly reduced the expression of interleukin-10 and interferon-gamma genes in the intestinal tissue, compared to the fatty liver group (P=0.001). Conclusion: According to the obtained data, HIIT and probiotic consumption can help modulate the expression of genes involved in the innate immune system of intestinal tissue caused by fatty liver.","PeriodicalId":340278,"journal":{"name":"Quarterly of the Horizon of Medical Sciences","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115033594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiology and Death Trends Due to Diabetes in Iran 伊朗糖尿病流行病学和死亡趋势

Quarterly of the Horizon of Medical Sciences Pub Date : 2021-03-10 DOI: 10.32598/hms.27.2.2764.1

Elnaz Jafarvand, A. Ataey, S. Edalati

{"title":"Epidemiology and Death Trends Due to Diabetes in Iran","authors":"Elnaz Jafarvand, A. Ataey, S. Edalati","doi":"10.32598/hms.27.2.2764.1","DOIUrl":"https://doi.org/10.32598/hms.27.2.2764.1","url":null,"abstract":"Aims: Diabetes mortality undergoes a growing trend worldwide that results in reducing life expectancy in society. Diabetes has been a significant health challenge in recent decades and imposed a lot of economic burden on the community. The present study aimed to evaluate the trend of diabetes mortality in Iran over five years. Methods & Materials: The mortality data published by the Ministry of Health and Medical Education has been used in this analytical cross-sectional study. The number and rate of diabetic cases are specified based on age, gender, location, and the death process from 2006 to 2010. Findings: About 54.9% and 45.1% of the deaths occurred in women and men, respectively, with a male to female ratio of 0.82. The highest death rate was observed in individuals aged above 70 and 50-69 years with an average age of 68.1 years. A higher mortality rate was observed in the cities than in the countryside, and 40% of deaths occurred due to non-insulin-dependent (type II) diabetes mellitus. Conclusion: Diabetes mortality has increased from 2006 to 2010. Higher deaths were observed in women and cities. Considering the increasing population of older adults in Iran, diabetes prevention and control interventions can be carried out through screening, planning, and education.","PeriodicalId":340278,"journal":{"name":"Quarterly of the Horizon of Medical Sciences","volume":"440 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115937399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

The Relationship of Psychological Wellbeing and Psychological Hardiness With the Mediating Role of Social Support in Women With Breast Cancer 乳腺癌妇女心理健康、心理抗逆性与社会支持的中介作用

Quarterly of the Horizon of Medical Sciences Pub Date : 2021-01-01 DOI: 10.32598/HMS.27.1.3093.2

Roya Azadi, H. Ahadi, H. Hatami

{"title":"The Relationship of Psychological Wellbeing and Psychological Hardiness With the Mediating Role of Social Support in Women With Breast Cancer","authors":"Roya Azadi, H. Ahadi, H. Hatami","doi":"10.32598/HMS.27.1.3093.2","DOIUrl":"https://doi.org/10.32598/HMS.27.1.3093.2","url":null,"abstract":"Aims: Breast cancer is the most common cancer in women and the first cause of cancer death. This study aims to determine the relationship between psychological wellbeing and psychological hardiness with the mediating role of social support in women with breast cancer. Methods & Materials This research was a correlation study based on Structural Equation Modeling (SEM). The study population consisted of women with breast cancer living in Mazandaran Province, Iran, in 2017. For this study, a sample of 236 patients with breast cancer was selected by the random sampling method. Then, Ryff psychological welfare questionnaire, Ahvaz hardiness inventory, and Berlin social support scales were administered to them. The obtained data were analyzed using the SEM. Findings: The correlation between variables of psychological wellbeing and psychological hardiness with social support was significant (P<0.001). Fit indices indicated an appropriate fit for the proposed model (P<0.05). There was also a significant relationship between psychological hardiness and psychological wellbeing through social support (P<0.05). Conclusion: Considering the importance of preserving and improving the quality of life of patients with breast cancer, the evaluation of psychological hardiness, and social support with psychological wellbeing, and proper intervention to improve the mental health of these patients, is recommended.","PeriodicalId":340278,"journal":{"name":"Quarterly of the Horizon of Medical Sciences","volume":"212 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116143364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Mediating Role of Alexithymia in the Relationship of Coping Strategies and Personality Traits With Obsessive-Compulsive Disorder

Quarterly of the Horizon of Medical Sciences Pub Date : 2021-01-01 DOI: 10.32598/HMS.27.1.3355.1

مسعود باقری, کاظم نعمتالهزاده ماهانی, مریم پورامرالهی

{"title":"The Mediating Role of Alexithymia in the Relationship of Coping Strategies and Personality Traits With Obsessive-Compulsive Disorder","authors":"مسعود باقری, کاظم نعمتالهزاده ماهانی, مریم پورامرالهی","doi":"10.32598/HMS.27.1.3355.1","DOIUrl":"https://doi.org/10.32598/HMS.27.1.3355.1","url":null,"abstract":"Aims: Obsessive-Compulsive Disorder (OCD) is one of the severe psychological health problems imposing considerable social and economic costs on society. OCD debilitating symptoms can disrupt interpersonal relations, job performance, and life quality. The purpose of this study is to investigate the mediating role of alexithymia in the relationship between coping strategies and personality traits with OCD. Methods & Materials: This is a descriptive correlational study. The study population consists of all people with OCD referred to psychiatric clinics in Kerman City, Iran, during 2018-2019. Of this population, 200 patients were selected using a convenience sampling method. Research instruments included the ways of coping questionnaire, NEO five-factor personality inventory, Toronto alexithymia scale, and Maudsley obsessive-compulsive test. The obtained data were analyzed using the Pearson correlation test and simultaneous and hierarchical regression in SPSS v. 23. Findings: Personality traits had a negative significant correlation with alexithymia (r=0.523, P<0.000) and OCD (r=0.253, P<0.000). Alexithymia had a significant positive correlation with OCD (r=0.272, P<0.000). There was no correlation between problem-focused coping and alexithymia (r=-0.045, P<0.531). There was a positive correlation between emotion-focused coping and OCD (r=0.198, P<0.000). The fit indices indicated a good fit of the proposed model (P<0.005). Conclusion: Alexithymia, as a mediator of the relationship between coping styles and personality traits with OCD, plays an essential role in improving the psychological health of people with OCD.","PeriodicalId":340278,"journal":{"name":"Quarterly of the Horizon of Medical Sciences","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125052475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Metabolic Effects of Methanol Extract of Harmal (Peganum Harmal ) in Rats Fed With Normal Diet 哈马甲醇提取物对正常饮食大鼠代谢的影响

Quarterly of the Horizon of Medical Sciences Pub Date : 2020-10-01 DOI: 10.32598/hms.26.4.2823.1

Esmail Mollashahi, H. Kazerani

{"title":"Metabolic Effects of Methanol Extract of Harmal (Peganum Harmal ) in Rats Fed With Normal Diet","authors":"Esmail Mollashahi, H. Kazerani","doi":"10.32598/hms.26.4.2823.1","DOIUrl":"https://doi.org/10.32598/hms.26.4.2823.1","url":null,"abstract":"Aims: The research aimed to investigate the effects of harmal (Peganum harmal ) seed extract on the weight and some metabolic parameters. Methods & Materials: Male rats, in groups of 7, received different doses of the methanol extract of harmal seed (100, 200, and 400 mg/kg/d body weight) or placebo via a gastric tube for 42 days. At the end of the experiment, the weights of the body, liver, spleen, and heart, and also the levels of some serum parameters, including glucose, cholesterol, triglyceride, low-density lipoprotein, high-density lipoprotein, insulin, growth hormone, and thyroid hormones, as well as the composition of the carcass were investigated. Findings: The mean weight gain, food intake, and the serum level of triiodothyronine (T3) significantly declined in the rats receiving the extract at 400 mg/kg. In contrast, the serum level of cholesterol in the group increased (P<0.001). The serum levels of glucose were significantly lower in all experimental groups compared to the control. Furthermore, the groups treated with the methanol extract dose-dependently showed higher serum lactate dehydrogenase levels compared to the control (P<0.05). No significant differences were observed regarding other studied parameters compared with the control group. Conclusion: This research suggests positive effects for harmal extract on some metabolic parameters and weight. At least one of the involved mechanisms seems to be declined appetite and hence decreased feed intake.","PeriodicalId":340278,"journal":{"name":"Quarterly of the Horizon of Medical Sciences","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131649528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Effect of the Cellular Extract of Co-cultured Lactobacillus Casei on BAX and Human β-Defensin 2 Genes Expression in HT29 Cells 共培养干酪乳杆菌细胞提取物对HT29细胞BAX和人β-防御素2基因表达的影响

Quarterly of the Horizon of Medical Sciences Pub Date : 2020-10-01 DOI: 10.32598/hms.26.4.3277.1

Mina Yavari, C. Ahmadizadeh

{"title":"Effect of the Cellular Extract of Co-cultured Lactobacillus Casei on BAX and Human β-Defensin 2 Genes Expression in HT29 Cells","authors":"Mina Yavari, C. Ahmadizadeh","doi":"10.32598/hms.26.4.3277.1","DOIUrl":"https://doi.org/10.32598/hms.26.4.3277.1","url":null,"abstract":"Aims: Defensins are cysteine-rich antimicrobial cationic peptides and BAX is a proapoptotic gene that can cause cell death. This study aimed to investigate the effect of cellular extract of co-cultured Lactobacillus casei on the expression of BAX and human β-defensin 2 (hBD-2) genes in HT29 cells. Methods & Materials: This experimental study was conducted in the Research Center for Pharmaceutical Nanotechnology of Tabriz University of Medical Sciences in 2017. The HT29 cell line was obtained from the Pasteur Institute of Iran, and cells were assessed using Microculture Tetrazolium Test (MTT) after culturing. DNA was extracted from the treated cells, and then the DNA ladder assay was carried out. After preparing cDNA, the expression levels of BAX and hBD-2 genes in the HT29 cell line were measured using a real-time Polymerase Chain Reaction (PCR) method. Findings: The results of the MTT assay indicated that Lactobacillus casei inhibited the proliferation of HT29 cells and induced apoptosis in these cells. Results of DAPI staining and DNA ladder assay obtained from treating HT29 cells by Lactobacillus casei showed qualitative changes in cell apoptosis. Moreover, realtime PCR results indicated that Lactobacillus casei bacteria significantly increased the expression of the hBD-2 gene in HT29 colon cancer cells within 12-24 hours (P= 0.023), while BAX gene expression showed no significant change in the first 24 hours (P= 0.37). Conclusion: The extract of Lactobacillus casei can be used to stimulate cancer cells to produce β-defensins, inhibit pathogens, prevent the stimulation of cellular signaling, and fight antibiotic-resistant bacteria.","PeriodicalId":340278,"journal":{"name":"Quarterly of the Horizon of Medical Sciences","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121314031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

A Two-Dimensional Convolutional Neural Network for Brain Tumor Detection From MRI 二维卷积神经网络在脑肿瘤MRI检测中的应用

Quarterly of the Horizon of Medical Sciences Pub Date : 2020-10-01 DOI: 10.32598/hms.26.4.3303.1

Ayoub Najaf-Zadeh

{"title":"A Two-Dimensional Convolutional Neural Network for Brain Tumor Detection From MRI","authors":"Ayoub Najaf-Zadeh","doi":"10.32598/hms.26.4.3303.1","DOIUrl":"https://doi.org/10.32598/hms.26.4.3303.1","url":null,"abstract":"Aims: Cancerous brain tumors are among the most dangerous diseases that lower the quality of life of people for many years. Their detection in the early stages paves the way for the proper treatment. The present study aimed to present a two-dimensional Convolutional Neural Network (CNN) for detecting brain tumors under Magnetic Resonance Imaging (MRI) using the deep learning method. Methods & Materials: The proposed method has two stages of feature extraction and classification. A 12-layer CNN was used to extract the features of the MRI images and then the softmax activation function was used to classify these features. The proposed method was applied to a standard database consisting of three brain tumor types of meningioma, glioma, and pituitary. Findings: The proposed method had better performance compared to previously presented methods. Its accuracy was reported as 98.68%. Conclusion: Meningioma, glioma, and pituitary tumors are the most common types of brain tumors. Early detection of these tumors can decrease the risk of death. Because of its fully connected structure, the use of proposed deep CNN can help physicians to correctly detect brain tumors with MRI images.","PeriodicalId":340278,"journal":{"name":"Quarterly of the Horizon of Medical Sciences","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127115815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Using the Backman Model in Determining the Dimensions of Self-Care and Its Factors Affecting the Elderly in Tehran City, Iran 利用Backman模型确定伊朗德黑兰市老年人自我照顾的维度及其影响因素

Quarterly of the Horizon of Medical Sciences Pub Date : 2020-10-01 DOI: 10.32598/hms.26.4.3251.1

L. Salehi, Leila Keikavoosi-Arani

引用次数: 5

Effect of Extracts of Cloves (Syzygium Aromaticum) on Hepatic Cell Damage and Oxidative Stress Caused by Diabetes in Adult Rats 丁香提取物对糖尿病大鼠肝细胞损伤及氧化应激的影响

Quarterly of the Horizon of Medical Sciences Pub Date : 2020-10-01 DOI: 10.32598/hms.26.4.3400.1

Tala Pourlak, M. Halimi, T. Pourlak, Parham Maroufi, Saber Ghaderpour, Arefeh Shokoohi

{"title":"Effect of Extracts of Cloves (Syzygium Aromaticum) on Hepatic Cell Damage and Oxidative Stress Caused by Diabetes in Adult Rats","authors":"Tala Pourlak, M. Halimi, T. Pourlak, Parham Maroufi, Saber Ghaderpour, Arefeh Shokoohi","doi":"10.32598/hms.26.4.3400.1","DOIUrl":"https://doi.org/10.32598/hms.26.4.3400.1","url":null,"abstract":"Aims: In this study, we investigated the effect of clove extract (Syzygium aromaticum) on liver cell damage and oxidative stress caused by diabetes in adult rats. Methods & Materials: For this study, 28 female rats were collected and divided into four groups: A: Control group; B: Diabetic Control group (DC) which received 20% glycerol dissolved in normal saline as carriers; C: Diabetic rats (DSA) treated with cloves hydroalcoholic extract (4 mg/kg); d) diabetic rats (DG) treated with glibenclamide (5 mg/kg) as a standard drug. Findings: The fasting blood sugar and serum triglyceride levels in the DC group increased significantly compared to the control group (P<0.05). In DC, DG, and DSA groups, high-density lipoprotein, and serum insulin levels decreased significantly compared to the control group (P<0.05). Also, in DG and DSA groups, high-density lipoprotein and serum insulin levels increased significantly compared to the DC group. Conclusion: Cloves can affect fasting blood sugar, serum insulin levels, serum fat profile levels, and prevent liver tissue damage in diabetic rats caused by streptozotocin.","PeriodicalId":340278,"journal":{"name":"Quarterly of the Horizon of Medical Sciences","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133852247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization of Antibiotic Resistance Profile and Detection of pap and blaCTX-Genes in Escherichia coli Isolates 大肠杆菌耐药性特征及pap和blactx基因检测

Quarterly of the Horizon of Medical Sciences Pub Date : 2020-10-01 DOI: 10.32598/HMS.26.4.1402.3

H. Naghizadeh, J. Mardaneh, A. Mosadegh, A. Astani

{"title":"Characterization of Antibiotic Resistance Profile and Detection of pap and blaCTX-Genes in Escherichia coli Isolates","authors":"H. Naghizadeh, J. Mardaneh, A. Mosadegh, A. Astani","doi":"10.32598/HMS.26.4.1402.3","DOIUrl":"https://doi.org/10.32598/HMS.26.4.1402.3","url":null,"abstract":"Aims Escherichia coli is one of the most important causes of hospital-acquired and community-acquired infections in humans and can easily gain resistance to antibiotics consumed by humans and animals. The main objectives of this study were to assess antibiotic resistance outlines and detection of antibiotic resistance and virulence genes, including the blaCTX-M and pap among the E. coli isolates recovered from the urine of patients referred to Shaheed Madani Hospital (Bejestan, Northeast of Iran). Methods & Materials This cross-sectional study was conducted from April 2016 to March 2018. A total of 100 non-duplicate isolates of E. coli were recovered from the urine of patients referred to Shaheed Madani Hospital (Bejestan, Northeast of Iran). Antimicrobial susceptibility test and extended-spectrum-beta-Lactamases (ESBLs) production were performed according to Clinical and Laboratory Standards Institute (CLSI) guidelines. The polymerase chain reaction was carried out for the detection and distribution of the pap virulence gene and blaCTX-M antibiotic resistance gene. Findings About 100 E. coli isolates were recovered from the urine sample of patients (21 male, and 79 female). Carbapenems were the most effective antibiotic against isolates. Four strains (4%) were resistant to colistin. Twenty-seven strains (27%) were ESBL-positive. Carbapenems were the most effective antibiotic against ESBL-positive strains. Also, 82% and 89% of isolates were blaCTX-M and pap gene positive, respectively. Conclusion This study has shown that ESBL-positive strains with a high level of drug resistance and virulence factors are a potential risk for hospital wards. Colistin resistant isolates found in our study are quite alarming.","PeriodicalId":340278,"journal":{"name":"Quarterly of the Horizon of Medical Sciences","volume":"99 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132827969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0