{"title":"Shock Waves and Radial Pressure Waves: Time to Put a Clear Nomenclature into Practice","authors":"A. Loske, D. Moya","doi":"10.13107/jrs.2021.v01.i01.005","DOIUrl":"https://doi.org/10.13107/jrs.2021.v01.i01.005","url":null,"abstract":"Extracorporeal focused shock wave therapy and radial pressure wave therapy are noninvasive approaches with high success rates that hold promise for treating a rapidly increasing number of clinical indications. However, reports, presentations at scientific meetings, and information published by manufacturers reflect confusion in the terminology used. This situation is worrisome because both desired and undesired biological effects depend on the pressure profile and the physical parameters used. Moreover, in many cases, the detailed biological mechanisms involved are yet not fully understood. Only a clear knowledge of the physical concepts can enable comparison among and improvement of treatment protocols and technology. Fortunately, specific definitions and recommendations have been agreed upon by scientific societies promoting international standardization. The main goal of this article is to raise awareness of the importance of having a clear nomenclature worldwide and explain some of the concepts based on the international consensus that has been accepted to date.","PeriodicalId":337981,"journal":{"name":"Journal of Regenerative Science","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129917355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eduard Alentorn-Geli, P. Laiz, Alfred Ferré-Aniorte, R. Seijas, P. Álvarez-Díaz, X. Cuscó, C. Sánchez, Luís García, M. García-Balletbó, R. Cugat
{"title":"Multilineage-differentiating Stress-enduring (MUSE) Cells in Orthobiologics: Are they the Future?","authors":"Eduard Alentorn-Geli, P. Laiz, Alfred Ferré-Aniorte, R. Seijas, P. Álvarez-Díaz, X. Cuscó, C. Sánchez, Luís García, M. García-Balletbó, R. Cugat","doi":"10.13107/jrs.2021.v01.i01.023","DOIUrl":"https://doi.org/10.13107/jrs.2021.v01.i01.023","url":null,"abstract":"Multilineage-differentiating stress-enduring (MUSE) cells are non-tumorigenic pluripotent stem cells with endogenous reparative properties. These cells have a very powerful ability to adapt to global environment changes and are thus stress-tolerant cells. Interestingly, MUSE cells can differentiate into cells representative of all three germ layers. There has been a number of studies demonstrating its powerful regenerative power in several disorders: type-1 diabetes mellitus, myocardial infarction, stroke, glomerular-related kidney diseases, chronic liver failure, and ischemia-reperfusion lung injury. Recent data have also suggested that MUSE cells have significant repair properties for osteochondral lesions. The present article will review what are MUSE cells and how they work, the application of these cells into different disorders, and the studies up-to-date regarding MUSE cells in orthobiologic.","PeriodicalId":337981,"journal":{"name":"Journal of Regenerative Science","volume":"206 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123059994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fundamentals of the Treatment of Male Erectile Dysfunctions with Low Intensity Shock Waves","authors":"César Eisner, Mauricio Salas, D. Moya","doi":"10.13107/jrs.2021.v01.i01.015","DOIUrl":"https://doi.org/10.13107/jrs.2021.v01.i01.015","url":null,"abstract":"Male erectile dysfunction (ED) is one of the most common problems among men worldwide. No single diagnostic method evaluates all the variables of this complex condition. To achieve good therapeutic results, it is essential to base the treatment on an accurate diagnosis.\u0000Hemodynamic exploration by echo Doppler of the cavernous arteries, especially since the incorporation of intracavernous administration of vasoactive drugs, is a useful tool that allows the evaluation of erectile dysfunction in the arterial phase. It is also considered to be the choice in the assessment of the corporoveno-occlusive mechanism. Different treatment methods are used, being PDE5 (sildenafil and tadalafil), the treatment of the first choice in several conditions. The number of publications of low-intensity extracorporeal shockwave treatment (LIESWT) for ED has increased dramatically in recent years. Scientific evidence regarding the application of LI-ESWT for the treatment of erectile dysfunction is still controversial. Inclusion criteria of the studies and the wide variety of treatment protocols have been criticized. On the other hand, most of these studies report encouraging results with no short-term adverse effects, regardless of variation in LI-ESWT setup parameters or treatment protocols.","PeriodicalId":337981,"journal":{"name":"Journal of Regenerative Science","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116663551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Plantar Fasciopathy, General Concepts, Shock Wave Treatment and Other Additional Therapeutic Considerations","authors":"Osvaldo Valle Toledo","doi":"10.13107/jrs.2021.v01.i01.021","DOIUrl":"https://doi.org/10.13107/jrs.2021.v01.i01.021","url":null,"abstract":"Plantar fasciopathy is the most common cause of heel pain. It is a primarily degenerative and mechanical overuse pathology. The plantar fascia fulfills important biomechanical functions in the foot, being its “windlass” mechanism, the most important function in this regard, allowing the foot to act as a single and efficient motor unit during gait. Its clinical and imaging diagnosis is fully defined, being Baxter’s nerve entrapment neuropathy, its most significant differential diagnosis. The elongation exercises constitute the basic treatment, being the extracorporeal shock wave therapy of significant utility, amplified in its effects by the association with the referred therapeutic exercises.","PeriodicalId":337981,"journal":{"name":"Journal of Regenerative Science","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132325851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Non Invasive Physical Regenerative Therapies: Laser Therapy, Mechanism of Action and Results","authors":"L. Guiloff, Ondrej Prouza, D. Žarković","doi":"10.13107/jrs.2021.v01.i01.013","DOIUrl":"https://doi.org/10.13107/jrs.2021.v01.i01.013","url":null,"abstract":"Low-level laser therapy (LLLT) and high-intensity laser therapy (HILT) have emerged as a therapeutic alternative suitable for a wide range of medical conditions. The main advantage of high-intensity laser over LLLT is its ability to deliver a much higher dose in a shorter time while achieving deeper penetration into the affected tissue and producing a thermal effect. Although HILT, provides very satisfactory clinical results, more clinical research is require to justify its massive use.","PeriodicalId":337981,"journal":{"name":"Journal of Regenerative Science","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126474515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Santos, Bruno Schiefer Dos Santos, Nacime Salomao, Barbachan Mansur
{"title":"Shockwave Therapy and Anesthesia: What Evidence is There?","authors":"P. Santos, Bruno Schiefer Dos Santos, Nacime Salomao, Barbachan Mansur","doi":"10.13107/jrs.2021.v01.i01.009","DOIUrl":"https://doi.org/10.13107/jrs.2021.v01.i01.009","url":null,"abstract":"ntroduction: The use of anesthetics on extracorporeal shockwave therapy (ESWT) for musculoskeletal disorders is a matter of debate. Although widely performed, especially on focal procedures, its scientific background is sparse. This study aims to review the current evidence on the use of anesthetics in ESWT.\u0000Methods: A literature review of the PubMed, Web of Science, Embase, EBSCO, and Cochrane Library databases was performed. Studies assessing or comparing the use of any type of anesthetic in any form of shockwave therapy were collected.\u0000\u0000Results: After inclusion and exclusion criteria assessment, a total of seven studies were found to directly address the subject and only four were original articles.\u0000Conclusion: The produced evidence is small and lacks methodological quality. These facts support the necessity for new studies using the present technology to determine the real effect of anesthetics on ESWT.\u0000\u0000Level of Evidence: Level V. Literature Review","PeriodicalId":337981,"journal":{"name":"Journal of Regenerative Science","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123479566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Journal of Regenerative Science: A step towards a more biological future","authors":"Ashok Shyam","doi":"10.13107/jrs.2021.v01.i01.001","DOIUrl":"https://doi.org/10.13107/jrs.2021.v01.i01.001","url":null,"abstract":"Restoration of Biology is essentially the core principle of Regenerative medicine. Regenerative Medicine is de ned as “Regenerative Medicine is an emerging interdisciplinary eld of research and clinical applications focused on the repair, replacement or regeneration of cells, tissues or organs to restore impaired function resulting from any cause, including congenital defects, disease, trauma and aging.” [1]. From the de nition is clear the optimal restoration of functional biology is the aim of Regenerative medicine as opposed to clinical medicine where most of the focus lies on treating the symptoms or the external causative factors","PeriodicalId":337981,"journal":{"name":"Journal of Regenerative Science","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122298415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasound Intervention Techniques to Treat Patellar Tendinopathy","authors":"","doi":"10.13107/jrs.2021.v01.i01.019","DOIUrl":"https://doi.org/10.13107/jrs.2021.v01.i01.019","url":null,"abstract":"Patellar tendinopathy is a very common, yet very difficult pathology to treat. Its’ frequency in elite athletes, especially in jumping sports, can go as high as 14%. Recently it has been suggested that chronic tendinopathy may be an active process of ongoing tendon degeneration bearing close relation with inflammation-mediated responses, the intensity of pain in patellar tendinopathy appears to have a stronger relation with the number of newly formed blood vessels observed on Doppler ultrasound. This article is a descriptive review of the available information which was obtained during a 1-month period (September 2021) and the following search keywords were used: interventional ultrasonography; patellar ligament; tendinopathy. Based on the information obtained, a total of 787 articles were revied, mainly published in the last 10 years in Pubmed, Medline, and SciELO databases; out of these, a total of 15 articles were used as citations. Even though conservative treatment is preferred as a first-line treatment, if, during a 6-month period it fails, then surgical treatment is proposed; however, recovery time is a crucial issue for elite athletes. Treatment by ultrasound-guided interventionism is presented as an effective alternative and allows athletes to return to their regular activities in less time, with optimal results. In the literature there are not many articles that describe the various techniques of ultrasound-guided interventionism for the treatment of patellar tendinopathy, thus, we have carried out this bibliographic review.","PeriodicalId":337981,"journal":{"name":"Journal of Regenerative Science","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122013236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quality standards and techniques for the application of focused shockwaves and radial pressure waves in musculoskeletal disorders","authors":"J. Eid, D. Moya","doi":"10.13107/jrs.2021.v01.i01.007","DOIUrl":"https://doi.org/10.13107/jrs.2021.v01.i01.007","url":null,"abstract":"Focused shockwaves and radial pressure waves are safe and effective if used correctly. Nevertheless, poor results and complications have been described due to missdiagnosis and technical errors. The aim of this review is to introduce the basic principles of quality and technical recommendations for each method.","PeriodicalId":337981,"journal":{"name":"Journal of Regenerative Science","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121995025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case report: Focused shock waves as a treatment option in failed rotator cuff calcification surgery","authors":"","doi":"10.13107/jrs.2021.v01.i01.027","DOIUrl":"https://doi.org/10.13107/jrs.2021.v01.i01.027","url":null,"abstract":"Introduction: Focused extracorporeal shock wave treatment has emerged as an alternative therapy before invasive procedures when conservative treatment has failed in rotator cuff calcifications. It can also be used when surgery has failed.\u0000Case Report: We report a case of failed surgery in which focused shock waves were used for treatment. We applied three sessions of focused electromagnetic waves (Dornier Compact Alpha) with an energy level of 0.20 mJ/mm2, 2000 pulses per sesión, every 2 weeks. The pain gradually disappeared and mobility was regaining. The radiographic control 2 months after the last session showed the total disappearance of the calcification. The end result was the complete disappearance of the symptoms.\u0000Conclusion: The effectiveness of shock waves, their non-invasiveness, safety, and cost efficiency justify their use both as an option before an invasive technique and when surgery has failed in the treatment of rotator cuff calcifications.\u0000","PeriodicalId":337981,"journal":{"name":"Journal of Regenerative Science","volume":"278 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132832815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}