Bangladesh Journal of Obstetrics & Gynaecology最新文献

{"title":"Abstract Vol. 34(2)","authors":"S. Khatun","doi":"10.3329/bjog.v34i2.58282","DOIUrl":"https://doi.org/10.3329/bjog.v34i2.58282","url":null,"abstract":"Abstract not available \u0000Bangladesh J Obstet Gynaecol, 2019; Vol. 34(2): 141-143","PeriodicalId":337805,"journal":{"name":"Bangladesh Journal of Obstetrics & Gynaecology","volume":"123 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116292534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective Analysis of Cervical Cancer Staging in two Cohorts and its Application in 2018 Revised FIGO Staging for Cancer Cervix","authors":"S. Khatun, J. Ferdous, S. Begum, Fowzia Hussain, Noor e Ferdous, Farhana Khatun, Farzana Sharmin Bithi, F. Nazir, Latifa Akter","doi":"10.3329/bjog.v34i2.58272","DOIUrl":"https://doi.org/10.3329/bjog.v34i2.58272","url":null,"abstract":"Introduction: cervical cancer is the second most common cancer of women in Bangladesh. Information about the extent of any cancer is critical for treatment planning .For the management of cervical cancer clinical staging is the first and foremost task and disease stage is the single most important prognostic factor. \u0000Objective: To know the distribution of clinical stages of cervical cancer, to validate the revised 2018 FIGO staging system for cervical cancer with a particular focus on stage 1B and to know the differences in distribution of stages among two cohort groups. \u0000Methods: Retrospective analysis was conducted among two cohorts of cervical cancer patients. First group of cervical cancer patients underwent Examination Under Anesthesia (EUA) for clinical staging during December 2011 to July 2017 and second cohort was the same type of patients undergoing same procedure by different group of observer from August 2017 to June 2019. Chi square test was done to know the difference in stages between two groups. P value <0.05 was considered as significant difference. \u0000Results: In the first (8.12.11-1.7.17) cohort ( n—479) maximum ( 68.21%) patients were between 41 to 60 years old. Similarly in the second ( 2.8.17—30.6.19 ) cohort ( n—256) maximum ( 63.45%) patients were between 41 to 60 years of age. Significant difference observed in the measurement of the size of the tumour when it was 2.1 to 4 cm in size. ( p value-0.001) . Great difference observed in performing cystoscopy during EUA ( p value -0.001) between two cohorts. In the first cohort 27.39% and in 2nd cohort only 2.73% patients underwent cystoscopy. Differences also observed in diagnosing stage 11A, B and 4 A diseases. \u0000Conclusion : The 2018 FIGO staging system for cervical cancer is useful to distinguish stage 1B disease and it is very fruitful in taking decision regarding management. An important information obtained from this analysis is that great variation can occur in diagnosing stages of cervical cancer by different group of observer. \u0000Bangladesh J Obstet Gynaecol, 2019; Vol. 34(2): 87-92","PeriodicalId":337805,"journal":{"name":"Bangladesh Journal of Obstetrics &amp; Gynaecology","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125455061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"History of Introduction of Bivalent Human Papilloma Virus 16/18 Vaccine in Bangladesh","authors":"S. Khatun","doi":"10.3329/bjog.v34i2.58269","DOIUrl":"https://doi.org/10.3329/bjog.v34i2.58269","url":null,"abstract":"Abstract not available \u0000Bangladesh J Obstet Gynaecol, 2019; Vol. 34(2): 68-70","PeriodicalId":337805,"journal":{"name":"Bangladesh Journal of Obstetrics &amp; Gynaecology","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131366589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abdominal Wall Endometriosis – Case Series","authors":"S. Nahar, Naznin Naher, Dilshad Jahan, S. Khaliduzzaman, Dilip Kumar Kundu","doi":"10.3329/bjog.v34i2.58281","DOIUrl":"https://doi.org/10.3329/bjog.v34i2.58281","url":null,"abstract":"Endometriosis is primarily a disease of pelvis. Extra pelvic endometriosis is defined, when eutrophic endometrial tissue is detected in any site other than pelvic cavity with the specification that this invasion is benign (non-neoplastic) in nature. Endometriotic lesions are usually found on the peritoneal surfaces of the reproductive organs and adjacent structures of the pelvis, but it can occur anywhere in the body. Extra pelvic endometriosis is a rare condition and it’s most common extra-pelvic location is the abdominal wall, occurring most frequently after cesarean delivery or any other abdominal surgery. Other sites are gastrointestinal tract, respiratory tract, pleura, pericardium, diaphragm and primary umbilical endometriosis. Patient’s usually present with painful mass in the abdominal wall during menstrual period, sometimes with a typical presentation, but recently incidences of scar endometriosis is increased. Two cases are presented here. To obtain a definitive diagnosis and optimal treatment for abdominal wall endometriosis, complete excision & histopathological examination are necessary. Here we presents 3 cases with umbilical endometriosis who presented between 13 to 28 years of age. Our all cases presented with a cyclical painful, abdominal mass and sometimes bleeding from umbilical mass. Also we highlight the importance of early recognition and appropriate surgical intervention to minimize morbidity and mortality from endometriosis. \u0000Bangladesh J Obstet Gynaecol, 2019; Vol. 34(2): 134-140","PeriodicalId":337805,"journal":{"name":"Bangladesh Journal of Obstetrics &amp; Gynaecology","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131715471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and Attitude of Health Care Providers on the Use of Partogram: A Study in Rural Bangladesh","authors":"Fahmida Sharmin Joty, A. Begum, Alpana Adhikary, Kishwar Sultana, A. Rahman, Farhana Dewan","doi":"10.3329/bjog.v34i2.58274","DOIUrl":"https://doi.org/10.3329/bjog.v34i2.58274","url":null,"abstract":"Background: This study was conducted to assess the knowledge and attitude of health care providers regarding effective use of the partogram in monitoring the progress of labour. \u0000Methods: A total fifty health care providers were assessed with a preformed questionnaire during pre and post exposure to a 5-day training program and their pre- and post-test scores were analyzed. Attitude was assessed by checking randomly selected 50 partographs filled up by trained health care providers. Their attitude also tested by direct interviewing with 50 service providers. \u0000Results: Mean age of the respondents was 31.22 (±6.32) years. There was significant improvement of test scores after the training program. Random partograph assessment showed 85.4% correct response. Majority respondents showed positive attitude towards the use of partograph. \u0000Conclusion: Results of this study shows that the 5-day training program on use of partograph is effective. But further training programs including refresher training and capacity building on programme is required for long term success on the use of partograph. \u0000Bangladesh J Obstet Gynaecol, 2019; Vol. 34(2): 99-105","PeriodicalId":337805,"journal":{"name":"Bangladesh Journal of Obstetrics &amp; Gynaecology","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133798990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increasing trends in Deep Infiltrating Endometriosis (DIE) with Bilateral Endometrioma from Adolescence till Menopause: Case Series","authors":"R. Bhatia, Naazbir Kaur, Sunita Mor, Shivangi Jain","doi":"10.3329/bjog.v34i2.58280","DOIUrl":"https://doi.org/10.3329/bjog.v34i2.58280","url":null,"abstract":"Deep infiltrating endometriosis has varying clinical presentaions with certain diagnostic signs and symptoms. Bilateral endometriomas alongwith DIE has been observed in all the age groups in this series at more than 35 years of age. \u0000Bangladesh J Obstet Gynaecol, 2019; Vol. 34(2): 127-133","PeriodicalId":337805,"journal":{"name":"Bangladesh Journal of Obstetrics &amp; Gynaecology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129337771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Utility of Biomarkers in Diagnosis and Management of High Grade Cervical Intraepithelial Neoplasia (HSIL)","authors":"J. Ferdous, S. Khatun, -. Ashrafunnessa, Shiuly Chowdhury, F. Begum, Latifa Akter, J. M. Khan","doi":"10.3329/bjog.v34i2.58271","DOIUrl":"https://doi.org/10.3329/bjog.v34i2.58271","url":null,"abstract":"Objective of the study: The increasing inter- and intra-observer variability in the diagnosis of CIN by histopathology has led to the advent of different biomarkers. The aim of this study is to evaluate Ki-67 and p16 INK4a marker in differentiating CIN lesions and the clinical utility of it in the management of high grade squamous intraepithelial lesions (HSIL). \u0000Materials and methods: This cross-sectional study has been carried out among the biopsy proved cases of CIN2 and CIN3 in which P16 and Ki-67 immunostain was performed in the Colposcopy clinic, Bangabandhu Sheikh Mujib Medical University (BSMMU) and Department of Pathology, BSMMU respectively from 14-3-17 to 30-05-18. Thirty-two cases were incorporated in the study by purposive sampling. Data was analyzed using SPSS version 17. \u0000Results: Among 32 cases of HSIL, 25 were diagnosed as CIN 2 (78.13 %) and 7 cases as CIN 3 (21.87 %) by histopathology. All the cases were subjected to immunohistochemistry with P16 and Ki 67. Regarding the status of P16, it was found positive only in 32% cases of CIN 2 but in 100% cases of CIN 3. Similarly, Ki67 was found positive in 36 % of CIN2 cases but in all cases of CIN 3 lesions. Thus immunostain confirmed one third histopathologically diagnosed CIN 2 cases. On the other hand, all cases of CIN 3 were confirmed as HSIL with the immunostain. All the cases of CIN 2 were reviewed for consensus opinion. Only 8 (32%) cases of CIN 2 were both immunostain positive , the review diagnosis by consensus opinion was also CIN 2 in those cases. One case (4%) of CIN 2 was P16 negative but Ki 67 positive, which ultimately revealed as immature squamous metaplasia. Sixteen cases of CIN 2 were negative for both P16 and Ki 67. Among these, majority cases (52%) , consensus opinion revealed as CIN 1 and 12% cases as immature squamous metaplasia. Therefore, an HSIL diagnosed by histopathology could be false positive in a significant number of cases and overtreatment of a false positive CIN 2 lesion can affect future reproductive status, also have some psychological consequences and economic burden in the health sector. \u0000Conclusion: By using the biomarkers, overtreatment and undertreatment of CIN can be avoided. All cases of CIN 2 should be carefully dealt with either review of the slides by consensus opinion or by doing immunohistochemistry if facility is available. \u0000Bangladesh J Obstet Gynaecol, 2019; Vol. 34(2): 79-86","PeriodicalId":337805,"journal":{"name":"Bangladesh Journal of Obstetrics &amp; Gynaecology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117069047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Human Papilloma Virus 16/18 Antibody Titer Seven Years after Vaccination with Cervarix among Adolescent Girls of Bangladesh","authors":"Chowdhury Shamima Sultana, S. Khatun, Sharif Masuma Ismat, M. Jahan","doi":"10.3329/bjog.v34i2.58270","DOIUrl":"https://doi.org/10.3329/bjog.v34i2.58270","url":null,"abstract":"Background: Prevention of HPV infection by prophylactic vaccination is a critical step in reducing the cervical cancer burden. A pilot study was conducted to evaluate the serological immune response to the bHPV vaccine in adolescent Bangladeshi girls at 7th months of vaccination. This is the first in depth follow up study in Bangladesh to directly evaluate the long-term immunogenicity of the bHPV vaccine by measuring sustained HPV16/18 antibody titer seven years after vaccination. \u0000Objective: To determine the long-term immune response against HPV16/18 induced by the immunization with bivalent human papilloma virus (bHPV) 16/18 ASO4 adjuvanted vaccine by measuring the antigen specific antibody titer. \u0000Materials & Method: This was a cross- sectional observational study conducted among 30 adolescent Bangladeshi girls from October 2015 to September 2016 who were vaccinated with 3 doses of bHPV vaccine from December 2008 to June 2009 in the Division of Gynaecological Oncology of BSMMU. Antibody titer against bHPV 16/18 ASO4 adjuvanted cervical cancer vaccine was measured in the serum of the 30 vaccinee in the Virology laboratory of BSMMU using DRG HPV IgG ELISA (REF.EIA- 4907) kit. Data were analyzed by using SPSS version 21. \u0000Results: The mean age of the population was 17.9±1.2 years. Among 30 vaccinated subjects, vaccine-induced long-term anti-HPV ELISA seropositivity was 93.33% (with 95% CI) for both HPV 16/18 types measured at year seven post-vaccination. Immunization with the HPV16/18 L1 virus-like particle vaccine adjuvanted with AS04 induced sustained high levels of antibodies among adolescent Bangladeshi girls against high-risk HPV genotypes 16/18. \u0000Conclusion: Vaccination with bHPV is predicted to provide long-term protection against HPV infection and subsequent development of high-grade cervical lesions and cancer. \u0000Bangladesh J Obstet Gynaecol, 2019; Vol. 34(2): 72-78","PeriodicalId":337805,"journal":{"name":"Bangladesh Journal of Obstetrics &amp; Gynaecology","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126750652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adenomyosis and Infertility","authors":"M. R. Begum, Nazia Ehsan","doi":"10.3329/bjog.v34i2.58278","DOIUrl":"https://doi.org/10.3329/bjog.v34i2.58278","url":null,"abstract":"Adenomyosis is an abnormal growth of endometrial glands and stroma into the myometrium causing diffusely enlarged uterus. Due to the abnormal growth of endometrial glands and stroma it causes severe pain during menstruation. Though USG and MRI can help, histopathology of the lesion is confirmatory diagnosis of the disease. It is one of the important causes of infertility with very poor prognosis. Any treatment modalities can fail when lesion is diffuse in nature. Surgery in the form of total hysterectomy is the definitive treatment for complete cure but hysterectomy is not logical for infertile patients. So, fertility sparing surgery can be done to improve fertility. Medical treatment in the form of GnRHa and different form of progesterones can be used to eliminate symptoms and to reduce the adenomyotic mass, which may improve the fertility status. Non-surgical High Intensity Focused Ultrasound (HIFU) is another option to reduce the size of the lesion. For reproduction active treatment is ideal to accelerate live birth. Controled ovarian hyperstimulation and Intrauterine Insemination (IUI) can be done if tube(s) are patent. If not, Assisted Reproductive Technology (ART) is the treatment of choice for this group of patients. \u0000Bangladesh J Obstet Gynaecol, 2019; Vol. 34(2): 112-123","PeriodicalId":337805,"journal":{"name":"Bangladesh Journal of Obstetrics &amp; Gynaecology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126252961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"BJOG yearly CME program Vol. 34(2)","authors":"S. Khatun","doi":"10.3329/bjog.v34i2.58285","DOIUrl":"https://doi.org/10.3329/bjog.v34i2.58285","url":null,"abstract":"Abstract not available \u0000Bangladesh J Obstet Gynaecol, 2019; Vol. 34(2): 149-150","PeriodicalId":337805,"journal":{"name":"Bangladesh Journal of Obstetrics &amp; Gynaecology","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125693615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}