Cardiac Failure Review最新文献

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Viscoelastic Haemostatic Assays in Cardiovascular Critical Care. 心血管危重症的粘弹性止血试验。
Cardiac Failure Review Pub Date : 2021-02-19 eCollection Date: 2020-03-01 DOI: 10.15420/cfr.2020.22
Aniket S Rali, Ahmed M Salem, Melat Gebre, Taylor M Garies, Siva Taduru, Arthur W Bracey
{"title":"Viscoelastic Haemostatic Assays in Cardiovascular Critical Care.","authors":"Aniket S Rali,&nbsp;Ahmed M Salem,&nbsp;Melat Gebre,&nbsp;Taylor M Garies,&nbsp;Siva Taduru,&nbsp;Arthur W Bracey","doi":"10.15420/cfr.2020.22","DOIUrl":"https://doi.org/10.15420/cfr.2020.22","url":null,"abstract":"<p><p>The initiation and management of anticoagulation is a fundamental practice for a wide variety of indications in cardiovascular critical care, including the management of patients with acute MI, stroke prevention in patients with AF or mechanical valves, as well as the prevention of device thrombosis and thromboembolic events with the use of mechanical circulatory support and ventricular assist devices. The frequent use of antiplatelet and anticoagulation therapy, in addition to the presence of concomitant conditions that may lead to a propensity to bleed, such as renal and liver dysfunction, present unique challenges. The use of viscoelastic haemostatic assays provides an additional tool allowing clinicians to strike a delicate balance of attaining adequate anticoagulation while minimising the risk of bleeding complications. In this review, the authors discuss the role that viscoelastic haemostatic assay plays in cardiac populations (including cardiac surgery, heart transplantation, extracorporeal membrane oxygenation, acute coronary syndrome and left ventricular assist devices), and identify areas in need of further study.</p>","PeriodicalId":33741,"journal":{"name":"Cardiac Failure Review","volume":"7 ","pages":"e01"},"PeriodicalIF":0.0,"publicationDate":"2021-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/62/ec/cfr-07-e01.PMC7919676.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25467261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Clinical Characteristics of De Novo Heart Failure and Acute Decompensated Chronic Heart Failure: Are They Distinctive Phenotypes That Contribute to Different Outcomes? 新发心力衰竭和急性失代偿慢性心力衰竭的临床特征:它们是导致不同结果的独特表型吗?
IF 4.2
Cardiac Failure Review Pub Date : 2021-02-19 eCollection Date: 2020-03-01 DOI: 10.15420/cfr.2020.20
Wilson Matthew Raffaello, Joshua Henrina, Ian Huang, Michael Anthonius Lim, Leonardo Paskah Suciadi, Bambang Budi Siswanto, Raymond Pranata
{"title":"Clinical Characteristics of De Novo Heart Failure and Acute Decompensated Chronic Heart Failure: Are They Distinctive Phenotypes That Contribute to Different Outcomes?","authors":"Wilson Matthew Raffaello, Joshua Henrina, Ian Huang, Michael Anthonius Lim, Leonardo Paskah Suciadi, Bambang Budi Siswanto, Raymond Pranata","doi":"10.15420/cfr.2020.20","DOIUrl":"10.15420/cfr.2020.20","url":null,"abstract":"<p><p>Heart failure is currently one of the leading causes of morbidity and mortality. Patients with heart failure often present with acute symptoms and may have a poor prognosis. Recent evidence shows differences in clinical characteristics and outcomes between de novo heart failure (DNHF) and acute decompensated chronic heart failure (ADCHF). Based on a better understanding of the distinct pathophysiology of these two conditions, new strategies may be considered to treat heart failure patients and improve outcomes. In this review, the authors elaborate distinctions regarding the clinical characteristics and outcomes of DNHF and ADCHF and their respective pathophysiology. Future clinical trials of therapies should address the potentially different phenotypes between DNHF and ADCHF if meaningful discoveries are to be made.</p>","PeriodicalId":33741,"journal":{"name":"Cardiac Failure Review","volume":"7 ","pages":"e02"},"PeriodicalIF":4.2,"publicationDate":"2021-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e2/96/cfr-07-e02.PMC7919682.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25467263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary Embolism and Heart Failure: A Reappraisal. 肺栓塞和心力衰竭:重新评估。
Cardiac Failure Review Pub Date : 2021-02-18 eCollection Date: 2020-03-01 DOI: 10.15420/cfr.2020.26
Mattia Arrigo, Lars Christian Huber
{"title":"Pulmonary Embolism and Heart Failure: A Reappraisal.","authors":"Mattia Arrigo,&nbsp;Lars Christian Huber","doi":"10.15420/cfr.2020.26","DOIUrl":"https://doi.org/10.15420/cfr.2020.26","url":null,"abstract":"<p><p>Acute heart failure and acute pulmonary embolism share many features, including epidemiological aspects, clinical presentation, risk factors and pathobiological mechanisms. As such, it is not surprising that diagnosis and management of these common conditions might be challenging for the treating physician, in particular when both are concomitantly present. While helpful guidelines have been elaborated for both acute heart failure and pulmonary embolism, not many studies have been published on the coexistence of these diseases. With a special focus on diagnostic tools and therapeutic options, the authors review the available literature and, when evidence is lacking, present their own approach to the management of dyspnoeic patients with acute heart failure and pulmonary embolism.</p>","PeriodicalId":33741,"journal":{"name":"Cardiac Failure Review","volume":"7 ","pages":"e03"},"PeriodicalIF":0.0,"publicationDate":"2021-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/24/80/cfr-07-e03.PMC7926477.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25467264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Acute Heart Failure in Coronavirus Disease 2019 and the Management of Comedications. 2019冠状病毒病急性心力衰竭及药物管理
Cardiac Failure Review Pub Date : 2020-11-23 eCollection Date: 2020-03-01 DOI: 10.15420/cfr.2020.24
Chia Siang Kow, Syed Shahzad Hasan
{"title":"Acute Heart Failure in Coronavirus Disease 2019 and the Management of Comedications.","authors":"Chia Siang Kow,&nbsp;Syed Shahzad Hasan","doi":"10.15420/cfr.2020.24","DOIUrl":"https://doi.org/10.15420/cfr.2020.24","url":null,"abstract":"","PeriodicalId":33741,"journal":{"name":"Cardiac Failure Review","volume":"6 ","pages":"e32"},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0f/76/cfr-06-e32.PMC7851738.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25343645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sodium-Glucose Co-transporter 2 Inhibitors in Heart Failure: Recent Data and Implications for Practice. 钠-葡萄糖共转运蛋白2抑制剂在心力衰竭中的应用:最新数据和实践意义。
Cardiac Failure Review Pub Date : 2020-11-13 eCollection Date: 2020-03-01 DOI: 10.15420/cfr.2020.23
Giuseppe Rosano, David Quek, Felipe Martínez
{"title":"Sodium-Glucose Co-transporter 2 Inhibitors in Heart Failure: Recent Data and Implications for Practice.","authors":"Giuseppe Rosano,&nbsp;David Quek,&nbsp;Felipe Martínez","doi":"10.15420/cfr.2020.23","DOIUrl":"https://doi.org/10.15420/cfr.2020.23","url":null,"abstract":"<p><p>Heart failure is a shared chronic phase of many cardiac diseases and its prevalence is on the rise globally. Previous large-scale cardiovascular outcomes trials of sodium.glucose co-transporter 2 (SGLT2) inhibitors in patients with type 2 diabetes (T2D) have suggested that these agents may help to prevent primary and secondary hospitalisation due to heart failure and cardiovascular death in these patients. Data from the Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure (DAPA-HF) and Empagliflozin Outcome Trial in Patients With Chronic Heart Failure With Reduced Ejection Fraction (EMPEROR-Reduced) have demonstrated the positive clinical impact of SGLT2 inhibition in patients with heart failure with reduced ejection fraction both with and without T2D. These data have led to the approval of dapagliflozin for the treatment of patients with heart failure with reduced ejection fraction, irrespective of T2D status. This article reviews the latest data reported from the DAPA-HF and EMPEROR-Reduced trials and their clinical implications for the treatment of patients with heart failure.</p>","PeriodicalId":33741,"journal":{"name":"Cardiac Failure Review","volume":"6 ","pages":"e31"},"PeriodicalIF":0.0,"publicationDate":"2020-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7f/87/cfr-06-e31.PMC7689869.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38688925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Corrigendum to: Pulmonary Hypertension in Heart Failure Patients. 心力衰竭患者肺动脉高压的勘误表。
Cardiac Failure Review Pub Date : 2020-10-23 eCollection Date: 2020-03-01 DOI: 10.15420/cfr.2020.1.1
Sriram D Rao, Srinath Adusumalli, Jeremy A Mazurek
{"title":"Corrigendum to: Pulmonary Hypertension in Heart Failure Patients.","authors":"Sriram D Rao,&nbsp;Srinath Adusumalli,&nbsp;Jeremy A Mazurek","doi":"10.15420/cfr.2020.1.1","DOIUrl":"https://doi.org/10.15420/cfr.2020.1.1","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.15420/cfr.2019.09.].</p>","PeriodicalId":33741,"journal":{"name":"Cardiac Failure Review","volume":"6 ","pages":"e30"},"PeriodicalIF":0.0,"publicationDate":"2020-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ec/16/cfr-06-e30.PMC7607380.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38571028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Exercise Training on Cardiac Function in Heart Failure with Preserved Ejection Fraction. 运动训练对保留射血分数心力衰竭患者心功能的影响。
Cardiac Failure Review Pub Date : 2020-10-16 eCollection Date: 2020-03-01 DOI: 10.15420/cfr.2020.17
Hidekatsu Fukuta
{"title":"Effects of Exercise Training on Cardiac Function in Heart Failure with Preserved Ejection Fraction.","authors":"Hidekatsu Fukuta","doi":"10.15420/cfr.2020.17","DOIUrl":"https://doi.org/10.15420/cfr.2020.17","url":null,"abstract":"<p><p>Nearly half of patients with heart failure in the community have heart failure with preserved ejection fraction (HFpEF). Patients with HFpEF are often elderly and their primary chronic symptom is severe exercise intolerance. Left ventricular diastolic dysfunction is associated with the pathophysiology of HFpEF and is an important contributor to exercise intolerance in HFpEF patients. The effects of exercise training on left ventricular diastolic function in HFpEF patients have been examined in several randomised clinical trials. Meta-analysis of the trials indicates that exercise training can provide clinically relevant improvements in exercise capacity without significant change in left ventricular structure or function in HFpEF patients. Further studies are necessary to elucidate the exact mechanisms of exercise intolerance in HFpEF patients and to develop recommendations regarding the most effective type, intensity, frequency, and duration of training in this group.</p>","PeriodicalId":33741,"journal":{"name":"Cardiac Failure Review","volume":"6 ","pages":"e27"},"PeriodicalIF":0.0,"publicationDate":"2020-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/06/6f/cfr-06-e27.PMC7592458.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38561088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Determinants of Functional Capacity and Quality of Life After Implantation of a Durable Left Ventricular Assist Device. 植入耐用左心室辅助装置后功能能力和生活质量的决定因素。
Cardiac Failure Review Pub Date : 2020-10-16 eCollection Date: 2020-03-01 DOI: 10.15420/cfr.2020.15
Kiran K Mirza, Finn Gustafsson
{"title":"Determinants of Functional Capacity and Quality of Life After Implantation of a Durable Left Ventricular Assist Device.","authors":"Kiran K Mirza,&nbsp;Finn Gustafsson","doi":"10.15420/cfr.2020.15","DOIUrl":"https://doi.org/10.15420/cfr.2020.15","url":null,"abstract":"<p><p>Continuous-flow left ventricular assist devices (LVAD) are increasingly used as destination therapy in patients with end-stage heart failure and, with recent improvements in pump design, adverse event rates are decreasing. Implanted patients experience improved survival, quality of life (QoL) and functional capacity (FC). However, improvement in FC and QoL after implantation is not unequivocal, and this has implications for patient selection and preimplantation discussions with patients and relatives. This article identifies preimplantation predictors of lack of improvement in FC and QoL after continuous-flow LVAD implantation and discusses potential mechanisms, allowing for the identification of potential factors that can be modified. In particular, the pathophysiology behind insufficient improvement in peak oxygen uptake is discussed. Data are included from 40 studies, resulting in analysis of >700 exercise tests. Mean peak oxygen uptake was 13.4 ml/kg/min (equivalent to 48% of predicted value; 259 days after implantation, range 31-1,017 days) and mean 6-minute walk test distance was 370 m (182 days after implantation, range 43-543 days). Finally, the interplay between improvement in FC and QoL is discussed.</p>","PeriodicalId":33741,"journal":{"name":"Cardiac Failure Review","volume":"6 ","pages":"e29"},"PeriodicalIF":0.0,"publicationDate":"2020-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/98/55/cfr-06-e29.PMC7592460.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38561090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Heart Failure With Mid-range or Recovered Ejection Fraction: Differential Determinants of Transition. 中程或恢复射血分数心力衰竭:过渡的不同决定因素。
Cardiac Failure Review Pub Date : 2020-10-16 eCollection Date: 2020-03-01 DOI: 10.15420/cfr.2020.13
Davide Margonato, Simone Mazzetti, Renata De Maria, Marco Gorini, Massimo Iacoviello, Aldo P Maggioni, Andrea Mortara
{"title":"Heart Failure With Mid-range or Recovered Ejection Fraction: Differential Determinants of Transition.","authors":"Davide Margonato,&nbsp;Simone Mazzetti,&nbsp;Renata De Maria,&nbsp;Marco Gorini,&nbsp;Massimo Iacoviello,&nbsp;Aldo P Maggioni,&nbsp;Andrea Mortara","doi":"10.15420/cfr.2020.13","DOIUrl":"https://doi.org/10.15420/cfr.2020.13","url":null,"abstract":"<p><p>The recent definition of an intermediate clinical phenotype of heart failure (HF) based on an ejection fraction (EF) of between 40% and 49%, namely HF with mid-range EF (HFmrEF), has fuelled investigations into the clinical profile and prognosis of this patient group. HFmrEF shares common clinical features with other HF phenotypes, such as a high prevalence of ischaemic aetiology, as in HF with reduced EF (HFrEF), or hypertension and diabetes, as in HF with preserved EF (HFpEF), and benefits from the cornerstone drugs indicated for HFrEF. Among the HF phenotypes, HFmrEF is characterised by the highest rate of transition to either recovery or worsening of the severe systolic dysfunction profile that is the target of disease-modifying therapies, with opposite prognostic implications. This article focuses on the epidemiology, clinical characteristics and therapeutic approaches for HFmrEF, and discusses the major determinants of transition to HFpEF or HFrEF.</p>","PeriodicalId":33741,"journal":{"name":"Cardiac Failure Review","volume":"6 ","pages":"e28"},"PeriodicalIF":0.0,"publicationDate":"2020-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/72/6c/cfr-06-e28.PMC7592465.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38561089","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Congestion and Diuretic Resistance in Acute or Worsening Heart Failure. 急性或加重心力衰竭的充血和利尿剂抵抗。
Cardiac Failure Review Pub Date : 2020-09-28 eCollection Date: 2020-03-01 DOI: 10.15420/cfr.2019.18
Ingibjörg Kristjánsdóttir, Tonje Thorvaldsen, Lars H Lund
{"title":"Congestion and Diuretic Resistance in Acute or Worsening Heart Failure.","authors":"Ingibjörg Kristjánsdóttir,&nbsp;Tonje Thorvaldsen,&nbsp;Lars H Lund","doi":"10.15420/cfr.2019.18","DOIUrl":"https://doi.org/10.15420/cfr.2019.18","url":null,"abstract":"<p><p>Hospitalisation for acute heart failure (AHF) is associated with high mortality and high rehospitalisation rates. In the absence of evidence-based therapy, treatment is aimed at stabilisation and symptom relief. The majority of AHF patients have signs and symptoms of fluid overload, and, therefore, decongestion is the number one treatment goal. Diuretics are the cornerstone of therapy in AHF, but the treatment effect is challenged by diuretic resistance and poor diuretic response throughout the spectrum of chronic to worsening to acute to post-worsening HF. Adequate dosing and monitoring and evaluation of diuretic effect are important for treatment success. Residual congestion at discharge is a strong predictor of worse outcomes. Therefore, achieving euvolaemia is crucial despite transient worsening renal function.</p>","PeriodicalId":33741,"journal":{"name":"Cardiac Failure Review","volume":"6 ","pages":"e25"},"PeriodicalIF":0.0,"publicationDate":"2020-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3d/29/cfr-06-e25.PMC7539143.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38479682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
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