Journal of Islamabad Medical and Dental College最新文献_第6页

Effect of Pretreatment of Lignocaine Versus Midazolam in the Prevention of Etomidate Induced Myoclonus 利多卡因预处理与咪达唑仑对依托咪酯性肌阵挛的预防作用

Journal of Islamabad Medical and Dental College Pub Date : 2023-01-03 DOI: 10.35787/jimdc.v11i4.661

F. Batool, A. Ali, S. Lodhi, J. Zahir

{"title":"Effect of Pretreatment of Lignocaine Versus Midazolam in the Prevention of Etomidate Induced Myoclonus","authors":"F. Batool, A. Ali, S. Lodhi, J. Zahir","doi":"10.35787/jimdc.v11i4.661","DOIUrl":"https://doi.org/10.35787/jimdc.v11i4.661","url":null,"abstract":"Background: The myoclonus after induction of anesthesia with etomidate can lead to increased risk of regurgitation and aspiration. We conducted this study to compare the effectiveness of midazolam and lidocaine for the prevention of etomidate induced myoclonus. \u0000Methodology: This randomized controlled trial was done in the Department of Anesthesiology and Intensive Care, Holy Family Hospital, Rawalpindi from January-June 2015 after approval of hospital ethical committee. Informed consent (written) was taken from 224 patients. Patients were allocated into 2 equal groups randomly with the help of computer-generated numbers. Two minutes after induction with etomidate, Group A got 1 ml of 2% lidocaine, and one ml (1 mg) of midazolam was given to Group B. Myoclonus was evaluated in the following one minute, after which 0.5 mg/kg of succinylcholine was given to the patient to facilitate endotracheal intubation. \u0000Time of onset of induction was marked by loss of eyelash reflex. Myoclonus was recorded at 20, 40, and 60 seconds. Drug was found to be effective if there was no myoclonus within one minute of etomidate induction. Analysis of data was done using SPSS 17. \u0000Results: Lignocaine was effective in preventing myoclonus in 55.40% of patients and Midazolam prevented it in 69.60%. The variation between the results of the groups was found significant statistically. (P< 0.05) \u0000Conclusion: Both midazolam and lignocaine are effective in preventing the occurrence of myoclonus associated with etomidate. However, midazolam is the more effective of the two drugs. \u0000Keywords: Etomidate, Lignocaine, Midazolam, Myoclonus \u0000 ","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":"108 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81667155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary Diffuse Large B Cell Lymphoma Presenting as Chest Wall Mass: A Case Report 原发性弥漫性大B细胞淋巴瘤表现为胸壁肿块1例

Journal of Islamabad Medical and Dental College Pub Date : 2023-01-03 DOI: 10.35787/jimdc.v11i4.903

Dr Muhammad Zeeshan, Professor Dr Shajee Ahmed Siddiqui, Dr Muhammad Azhar Jamil, Dr Ghazal Iftikhar, Dr Adil Farooq

引用次数: 0

Perception of Ethics and Professionalism Teaching among Dental Professionals at a Teaching Hospital in Karachi 卡拉奇某教学医院牙科专业人员的道德观念与专业教学

Journal of Islamabad Medical and Dental College Pub Date : 2023-01-03 DOI: 10.35787/jimdc.v11i4.645

Rubab Jawed, Dr Ruqayyah Quresh Hashmi, Dr Hafsa Usman, Dr Mehtab, Dr Saba Sabir

{"title":"Perception of Ethics and Professionalism Teaching among Dental Professionals at a Teaching Hospital in Karachi","authors":"Rubab Jawed, Dr Ruqayyah Quresh Hashmi, Dr Hafsa Usman, Dr Mehtab, Dr Saba Sabir","doi":"10.35787/jimdc.v11i4.645","DOIUrl":"https://doi.org/10.35787/jimdc.v11i4.645","url":null,"abstract":"Background: Health care professionals come across many ethically difficult situations in their clinical practices and community; the students should be equipped with skills to resolve ethical and professional issues. \u0000Methodology: A cross-sectional study was conducted at Baqai dental college, Karachi. All the faculty members and house officers of the dental teaching hospital were included in the study. The tool used for the data collection was a structured questionnaire, for drawing views of the participants on professionalism and ethics teaching. The survey instrument evaluated two domains; attitudes 25 items, and goals 19 items on ethics and professionalism education. Data were recorded and analyzed in SPSS 24. To compare the responses of both the groups, that is, the house officers and the faculty member’s independent t-test was applied to compare the mean scores. A p-value of ≤ 0.05 was considered significant. \u0000Results: The questionnaire was circulated to a total of 157 participants (75 faculty members and 82 house officers) with a 100% response rate. The faculty members and the house officers showed a positive attitude regarding ethics, professionalism, and teachings. The participants agreed with the goals that can be achieved by incorporating professionalism and medical ethics in education. The participant strongly affirmed the learning and teaching of professionalism (4.06 ± 0.989). \u0000Conclusion: The realization of the need to teach ethics and professionalism by dental professionals is the first step to bringing change in their daily clinical practice and interpersonal qualities. \u0000Keywords: Ethics, Professionalism, “Education, Medical”, “Personality development”, “Social Desirability”. \u0000 ","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90305058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Benefits of Tissue Marking by Poster Ink in Histopathology 海报油墨组织标记在组织病理学中的比较效益

Journal of Islamabad Medical and Dental College Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.751

Dr. Ayesha Sarwar, Prof. Ashok Kumar Tanwni, Dr. Anum Usman, Khalida Moeed

{"title":"Comparative Benefits of Tissue Marking by Poster Ink in Histopathology","authors":"Dr. Ayesha Sarwar, Prof. Ashok Kumar Tanwni, Dr. Anum Usman, Khalida Moeed","doi":"10.35787/jimdc.v11i3.751","DOIUrl":"https://doi.org/10.35787/jimdc.v11i3.751","url":null,"abstract":"Background: Tissue margin marking with India ink is important in decision making for surgeons. The present study was conducted to examine the reliability of different shades of locally available poster colours in tissue marking and to evaluate the colour perceptibility microscopically in comparison with similar tissues marked by India ink. \u0000Methodology: This experimental study was conducted at Department of Pathology, HBS Medical & Dental College & Hospital, Islamabad from 27th February 2021 to 29th April 2021. Sample size was fifty, collected through convenient sampling technique. Five types of formalin fixed tissue specimens were selected for the study so as to evaluate the effectiveness of poster ink marking on different tissue surfaces. From each specimen, four sections were taken from the margins. Three shades of poster colour (black, blue and green) were used to ink three sections while one section from each tissue type was marked with India ink. After complete tissue processing and routine haematoxylin and eosin (H&E) staining, slides were examined microscopically. Scoring was done on a scale 0 to 3 on the basis of visibility. \u0000Results: The present study showed that poster colours inking of the tissues was quite reliable as compared to India ink. Most consistent results were achieved with black and blue colours as compared to green colour. \u0000Conclusion: Poster colours are reliable tool for tissue marking when India ink is not available. Their availability in a variety of colours provides them an edge over India ink. \u0000Key words: Eosin, India ink, Resection Margins","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89850154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Universal Health Coverage in Pakistan: A call for Health System Reforms 巴基斯坦全民健康覆盖:呼吁卫生系统改革

Journal of Islamabad Medical and Dental College Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.910

Admin Jimdc, Baba Sheikh

{"title":"Universal Health Coverage in Pakistan: A call for Health System Reforms","authors":"Admin Jimdc, Baba Sheikh","doi":"10.35787/jimdc.v11i3.910","DOIUrl":"https://doi.org/10.35787/jimdc.v11i3.910","url":null,"abstract":"The sustainable development goal 3.8, adopted in 2015 by the United Nations advocated the need for ‘Universal Health Coverage’ (UHC), a roadmap promising that all people, particularly those in need, have access to essential health services when and where they need, without any financial hardship. UHC is not a new lexicon, it was outlined in the founding constitution of the World Health Organization (WHO) that has stipulated health as a fundamental and universal right of every human being without distinction of race, religion and political belief, economic and social condition. WHO defines ‘maximum’ population coverage, health service coverage, and financial protection, as three dimensions of UHC. The first dimension is relatively simpler to understand: what proportion of the people in the catchment of a health facility are covered for health services, and how many are left out. The second dimension delineates the range of essential health services made available to the people e.g. immunization, family planning, antenatal care, delivery by skilled birth attendant, treatment of common ailments, and services for HIV/AIDS, tuberculosis and malaria etc. Third dimension is about the expenditure incurred while seeking the healthcare, especially the out of pocket expenditure or the cost sharing by the patient, which is supposed","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83164559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utility of Cell Block with p53 Immunostain in Diagnosing Urothelial Carcinoma 细胞阻滞与p53免疫染色在尿路上皮癌诊断中的应用

Journal of Islamabad Medical and Dental College Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.709

N. Nabi, A. Ali, M. Fatima, Armaghana Qamar Khan, Henna Azmat, Ashok Kumar Tanwani

{"title":"Utility of Cell Block with p53 Immunostain in Diagnosing Urothelial Carcinoma","authors":"N. Nabi, A. Ali, M. Fatima, Armaghana Qamar Khan, Henna Azmat, Ashok Kumar Tanwani","doi":"10.35787/jimdc.v11i3.709","DOIUrl":"https://doi.org/10.35787/jimdc.v11i3.709","url":null,"abstract":"Background: Urine cytology is an initial noninvasive screening test done in patients with suspected urothelial carcinoma. The objective of this study was to compare the sensitivity of conventional smear cytology with cell block technique for the diagnosis of malignant cells in urine and to assess the efficacy of p53 immuno-marker in the diagnosis and prognosis of urinary bladder cancer. \u0000Methodology: The study was carried out in the department of Histopathology, Pakistan Institute of Medical Sciences(PIMS), Islamabad. Cell blocks and cytology smears and were prepared from urine samples of 80 patients of urothelial carcinoma and p53 stain was applied. Data was analyzed using version 21. Sensitivity of conventional smear and cell block techniques were calculated for both low and high grade urothelial carcinomas. \u0000Results:The sensitivity of detecting atypical cells using conventional smear was 31% and 70.6% for low grade and high grade urothelial tumors respectively. The sensitivity increased to 41.4% and 84.3% for low and high grade urothelial carcinomas respectively with cell block technique. Positive p53 stain was seen in 13.8% of cases with low grade tumors and 66.7% cases with high grade tumors. Chi-square test was used to find the association of cytology findings with the histologic grade. \u0000Conclusion: Sensitivity of urine cell blocks is higher than the conventional smear method for detecting high grade lesions. It can be used as an efficient non-invasive technique and an adjunct tool for the determination of disease relapse and overall survival in patients. \u0000Keywords: Carcinoma, Cytology, P53 Protein, Urine","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86732582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Audit of Laparoscopic Cholecystectomy; at a Tertiary Care Hospital in Islamabad 腹腔镜胆囊切除术的审计分析在伊斯兰堡的一家三级护理医院

Journal of Islamabad Medical and Dental College Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.774

M. Ullah

{"title":"An Audit of Laparoscopic Cholecystectomy; at a Tertiary Care Hospital in Islamabad","authors":"M. Ullah","doi":"10.35787/jimdc.v11i3.774","DOIUrl":"https://doi.org/10.35787/jimdc.v11i3.774","url":null,"abstract":"Background: Laparoscopic Cholecystectomy is a commonly performed surgery and is a gold standard for the treatment of cholelithiasis as it has fewer side effects. This study was conducted to determine indications and complications of this surgery at a tertiary care hospital in Islamabad. \u0000Methodology: This retrospective study was conducted in the department of Surgery, Maroof International Hospital from March 2017 to March 2019. A total of 250 patients who underwent laparoscopic cholecystectomy were included through consecutive sampling technique. The data regarding age, gender, mode of presentation, types of presentation, per operative findings, operative complications and duration of hospital stay was collected from patients’ medical record. Statistical Package for Social Sciences SPSS version 23 was used to analyze data. \u0000Results: Mean age of the participants was 46.24 ± 14.13 years. Female to male ratio was 2.73:1. Almost 38.4% patients had chronic cholecystitis, 35.2% had symptomatic gallstone disease, 24.8% had acute cholecystitis and 1.6% had gallbladder polyps. No major vascular or common bile duct injury were noted. 27.2% patients had per operative gallbladder perforation. Stone spillage occurred in 8.8% patients with retrieval in all of them. 75.2% patients were discharged on day 1. Per operatively, 98.4% patients had cholelithiasis, 59.6% had adhesions, 9.6% had mucocele, 1.6% had empyema and 0.8% patients had collections. \u0000Conclusion: Laparoscopic cholecystectomy is a safe procedure in all types of gallstone disease presentations with low complication rate. \u0000Key words: Cholelithiasis, Gallstones, Laparoscopic Cholecystectomy, Per-operative complications","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":"302 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89043514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mitotic Index and Immunohistochemical Expression of Ki-67 in Pleomorphic Adenoma of Salivary Glands 涎腺多形性腺瘤有丝分裂指数及Ki-67免疫组织化学表达

Journal of Islamabad Medical and Dental College Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.777

Faiz Rasul

{"title":"Mitotic Index and Immunohistochemical Expression of Ki-67 in Pleomorphic Adenoma of Salivary Glands","authors":"Faiz Rasul","doi":"10.35787/jimdc.v11i3.777","DOIUrl":"https://doi.org/10.35787/jimdc.v11i3.777","url":null,"abstract":". \u0000Background: Pleomorphic adenomas (PAs) are the most common type of salivary gland tumors (SGTs) which may undergo malignant transformation to Carcinoma ex PA (CaExPA). The purpose of this study was to determine mitotic index (MI) and expression of Ki-67 in Pleomorphic adenomas of salivary gland tumors. \u0000Methodology: This study was carried out on sixty patients of pleomorphic adenoma. Slides with specimens were stained with Hematoxylin & Eosin to count Mitotic index. Labeling Index (LI) of Ki-67 was determined immunohistochemically. Mitotic figures (MF) were counted in 10 HPF selected in the proliferative area. MI was scored as 1 (0 to 4 MF per 10 HPF); 2 (5-9 MF per 10 HPF) and 3 (> 9 MF per 10 HPF). Immunoexpression of Ki-67 was scored as ‘0-negative’ when <5% of neoplastic cells stained, ‘1-weak positive’ when 5-19% of neoplastic cells were stained, ‘2-moderate positive’ when 20-49% of neoplastic cells were stained, and ‘3-strong positive’ when >50% of neoplastic cells were stained with Ki-67. Data was, entered in SPSS 21. \u0000Results: Mean age was 38.7 ± 12.86 years. Out of 60 cases, 26 (43.33%) were of males while 34 (56.67%) were of females. Expression of Ki-67 was negative in 50% while remaining weak positive. Only score 01 of MI observed. \u0000Conclusion: Ki-67 is more sensitive marker than mitotic index in pleomorphic adenomas even in small sized tumors and it can help in detection of malignant transformation of PAs. \u0000Keywords: Adenomas, Immunohistochemistry, Ki-67 Antigen, Parotid Neoplasms, Pleomorphic","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":"75 16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81275037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A breakthrough in Alzheimer’s Disease 阿尔茨海默病的一个突破

Journal of Islamabad Medical and Dental College Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.793

Taimoor Hassan

引用次数: 0

The Impact of Disease Severity and Treatment on Quality of Life in Patients of Psoriasis 疾病严重程度及治疗对银屑病患者生活质量的影响

Journal of Islamabad Medical and Dental College Pub Date : 2022-09-28 DOI: 10.35787/jimdc.v11i3.823

Palvisha Qadri, S. Tabassum, U. Chhipa

{"title":"The Impact of Disease Severity and Treatment on Quality of Life in Patients of Psoriasis","authors":"Palvisha Qadri, S. Tabassum, U. Chhipa","doi":"10.35787/jimdc.v11i3.823","DOIUrl":"https://doi.org/10.35787/jimdc.v11i3.823","url":null,"abstract":"Background: Psoriasis is a common inflammatory dermatosis with significantly challenging clinical needs in patient management. Given its chronicity and social stigmatization, the burden on health-related life quality is substantial. The objective of this study was to assess psychosocial and financial impact of disease severity and treatment modalities on patients’ life quality. \u0000Methodology: A total of 93 clinically diagnosed patients with Psoriasis were included in this cross-sectional study. Quality of life was assessed through Dermatology Life Quality Index (DLQI) scoring system and disease severity by Psoriasis area severity index (PASI) respectively. Treatment modalities were evaluated by filling out a brief questionnaire. Descriptive analyses were presented as mean ± SD for symmetrically distributed variables while median with interquartile range (IQR) were reported for non-symmetrically distributed variables. Association was determined by Chi-square test considering p-value ≤0.05 as significant. \u0000Results: There were 47.3% male and 52.7% female patients. The Median DLQI score was 6.00 with an IQR of 7. Topical treatment was used in the majority of patients currently (60%). Quality of life ( QOL) for 41.9% of cases was mildly affected. Rest of the cases were affected more severely, consisting of 47.3% with moderate and 10.8% with severe impact on quality of life. Significant association of DLQI scores was found with disease severity and current treatment modalities. \u0000Conclusion: Different therapies along with disease severity, remarkably affect QoL among psoriasis patients. \u0000KEYWORDS \u0000Disease Severity ,Impact, Psoriasis , Quality of Life, Treatment","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":"116 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79639180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0