{"title":"疾病严重程度及治疗对银屑病患者生活质量的影响","authors":"Palvisha Qadri, S. Tabassum, U. Chhipa","doi":"10.35787/jimdc.v11i3.823","DOIUrl":null,"url":null,"abstract":"Background: Psoriasis is a common inflammatory dermatosis with significantly challenging clinical needs in patient management. Given its chronicity and social stigmatization, the burden on health-related life quality is substantial. The objective of this study was to assess psychosocial and financial impact of disease severity and treatment modalities on patients’ life quality. \nMethodology: A total of 93 clinically diagnosed patients with Psoriasis were included in this cross-sectional study. Quality of life was assessed through Dermatology Life Quality Index (DLQI) scoring system and disease severity by Psoriasis area severity index (PASI) respectively. Treatment modalities were evaluated by filling out a brief questionnaire. Descriptive analyses were presented as mean ± SD for symmetrically distributed variables while median with interquartile range (IQR) were reported for non-symmetrically distributed variables. Association was determined by Chi-square test considering p-value ≤0.05 as significant. \nResults: There were 47.3% male and 52.7% female patients. The Median DLQI score was 6.00 with an IQR of 7. Topical treatment was used in the majority of patients currently (60%). Quality of life ( QOL) for 41.9% of cases was mildly affected. Rest of the cases were affected more severely, consisting of 47.3% with moderate and 10.8% with severe impact on quality of life. Significant association of DLQI scores was found with disease severity and current treatment modalities. \nConclusion: Different therapies along with disease severity, remarkably affect QoL among psoriasis patients. \nKEYWORDS \nDisease Severity ,Impact, Psoriasis , Quality of Life, Treatment","PeriodicalId":33701,"journal":{"name":"Journal of Islamabad Medical and Dental College","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Impact of Disease Severity and Treatment on Quality of Life in Patients of Psoriasis\",\"authors\":\"Palvisha Qadri, S. Tabassum, U. Chhipa\",\"doi\":\"10.35787/jimdc.v11i3.823\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Psoriasis is a common inflammatory dermatosis with significantly challenging clinical needs in patient management. Given its chronicity and social stigmatization, the burden on health-related life quality is substantial. The objective of this study was to assess psychosocial and financial impact of disease severity and treatment modalities on patients’ life quality. \\nMethodology: A total of 93 clinically diagnosed patients with Psoriasis were included in this cross-sectional study. Quality of life was assessed through Dermatology Life Quality Index (DLQI) scoring system and disease severity by Psoriasis area severity index (PASI) respectively. Treatment modalities were evaluated by filling out a brief questionnaire. Descriptive analyses were presented as mean ± SD for symmetrically distributed variables while median with interquartile range (IQR) were reported for non-symmetrically distributed variables. Association was determined by Chi-square test considering p-value ≤0.05 as significant. \\nResults: There were 47.3% male and 52.7% female patients. The Median DLQI score was 6.00 with an IQR of 7. Topical treatment was used in the majority of patients currently (60%). Quality of life ( QOL) for 41.9% of cases was mildly affected. Rest of the cases were affected more severely, consisting of 47.3% with moderate and 10.8% with severe impact on quality of life. Significant association of DLQI scores was found with disease severity and current treatment modalities. \\nConclusion: Different therapies along with disease severity, remarkably affect QoL among psoriasis patients. \\nKEYWORDS \\nDisease Severity ,Impact, Psoriasis , Quality of Life, Treatment\",\"PeriodicalId\":33701,\"journal\":{\"name\":\"Journal of Islamabad Medical and Dental College\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-09-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Islamabad Medical and Dental College\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.35787/jimdc.v11i3.823\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Islamabad Medical and Dental College","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.35787/jimdc.v11i3.823","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
背景:银屑病是一种常见的炎症性皮肤病,在患者管理方面具有显著的临床挑战性。鉴于其长期性和社会污名化,与健康有关的生活质量负担沉重。本研究的目的是评估疾病严重程度和治疗方式对患者生活质量的心理社会和经济影响。方法:本横断面研究共纳入93例临床诊断为银屑病的患者。采用Dermatology life Quality Index (DLQI)评分系统评价生活质量,采用Psoriasis area severity Index (PASI)评价疾病严重程度。通过填写一份简短的问卷来评估治疗方式。对于对称分布的变量,描述性分析采用均数±标准差表示,而对于非对称分布的变量,采用四分位数范围(IQR)的中位数报告。以p值≤0.05为显著性,采用卡方检验确定相关性。结果:男性占47.3%,女性占52.7%。DLQI评分中位数为6.00,IQR为7。目前大多数患者(60%)采用局部治疗。41.9%的患者生活质量(QOL)轻度受影响。其余病例影响较严重,其中47.3%为中度影响,10.8%为重度影响。DLQI评分与疾病严重程度和当前治疗方式有显著关联。结论:不同治疗方法对银屑病患者的生活质量有显著影响。关键词:疾病严重程度,影响,银屑病,生活质量,治疗
The Impact of Disease Severity and Treatment on Quality of Life in Patients of Psoriasis
Background: Psoriasis is a common inflammatory dermatosis with significantly challenging clinical needs in patient management. Given its chronicity and social stigmatization, the burden on health-related life quality is substantial. The objective of this study was to assess psychosocial and financial impact of disease severity and treatment modalities on patients’ life quality.
Methodology: A total of 93 clinically diagnosed patients with Psoriasis were included in this cross-sectional study. Quality of life was assessed through Dermatology Life Quality Index (DLQI) scoring system and disease severity by Psoriasis area severity index (PASI) respectively. Treatment modalities were evaluated by filling out a brief questionnaire. Descriptive analyses were presented as mean ± SD for symmetrically distributed variables while median with interquartile range (IQR) were reported for non-symmetrically distributed variables. Association was determined by Chi-square test considering p-value ≤0.05 as significant.
Results: There were 47.3% male and 52.7% female patients. The Median DLQI score was 6.00 with an IQR of 7. Topical treatment was used in the majority of patients currently (60%). Quality of life ( QOL) for 41.9% of cases was mildly affected. Rest of the cases were affected more severely, consisting of 47.3% with moderate and 10.8% with severe impact on quality of life. Significant association of DLQI scores was found with disease severity and current treatment modalities.
Conclusion: Different therapies along with disease severity, remarkably affect QoL among psoriasis patients.
KEYWORDS
Disease Severity ,Impact, Psoriasis , Quality of Life, Treatment