Issues and Development in Health Research Vol. 2最新文献

Developing Preventive, Curative and Recovery (PCR) Strategy for Managing COVID-19 制定预防、治疗和恢复(PCR)战略以管理COVID-19

Issues and Development in Health Research Vol. 2 Pub Date : 2021-08-07 DOI: 10.9734/bpi/idhr/v2/2527e

A. Kumari, Vikash Kumar

引用次数: 0

Determining the Human Blastocyst Transfer for Success Rate in Artificial Reproductive Technology (ART) Treatment 确定人类囊胚移植在人工生殖技术治疗中的成功率

Issues and Development in Health Research Vol. 2 Pub Date : 2021-08-07 DOI: 10.9734/bpi/idhr/v2/3150f

A. Mettler, S. Otte, V. Guenther, I. Alkatout, L. Mettler

{"title":"Determining the Human Blastocyst Transfer for Success Rate in Artificial Reproductive Technology (ART) Treatment","authors":"A. Mettler, S. Otte, V. Guenther, I. Alkatout, L. Mettler","doi":"10.9734/bpi/idhr/v2/3150f","DOIUrl":"https://doi.org/10.9734/bpi/idhr/v2/3150f","url":null,"abstract":"All over the world, many of the ART centers, especially those without experience perform Cleavage stage and not blastocyst transfers. Although it has been proved without doubt that Blastocyst transfer is better, the personal experience of failure after shifting to Blastocyst transfer has demotivated many from the shift. The aim of this article is to explain to the reader how we at the University hospital took evidence based decisions and improved our culture conditions while increasing our pregnancy rates. Although the outcome of an ART cycle depends on a multitude of clinical and laboratory factors, this study pursued to critically explore the various advantages and disadvantages of changing the protocol in a German lab to international standards where blastocyst culture is the norm. 1126 ART cycles were performed from 2014 to 2018 in the University Reproductive Medical Unit of UKSH, Kiel. There was an improvement in pregnancy rates from 2014 to 2018 in both cleavage stage transfer (day 3) and blastocyst transfer with a 1.4 time increase every year. Improvement in the lab culture conditions had profound effect in increasing pregnancy rates. The article aims at encouraging the reader to make decisions to improve lab blastocyst culture conditions before shifting to blastocyst culture to improve pregnancy rates and not blindly shift overnight to blastocyst for all.","PeriodicalId":334876,"journal":{"name":"Issues and Development in Health Research Vol. 2","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128728150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

African Americans and Depression: The Development of a Culturally Competent Depression Scale for Reducing Treatment Disparities 非裔美国人与抑郁症:为减少治疗差异而制定的文化能力抑郁症量表

Issues and Development in Health Research Vol. 2 Pub Date : 2021-08-07 DOI: 10.9734/bpi/idhr/v2/3202f

B. Kennedy

{"title":"African Americans and Depression: The Development of a Culturally Competent Depression Scale for Reducing Treatment Disparities","authors":"B. Kennedy","doi":"10.9734/bpi/idhr/v2/3202f","DOIUrl":"https://doi.org/10.9734/bpi/idhr/v2/3202f","url":null,"abstract":"African Americans suffer depression for a longer period than their White counterparts. Often, African Americans are misdiagnosed and under-treated in the conventional healthcare system. Research studies reported the symptoms of depression among African Americans are inconsistent with the DSM-V. Previous Depression scales have not been culturally competent reflecting the depression symptoms of African Americans. This chapter address the treatment disparities in African Americans and the need for more culturally competent depression scales. The researcher developed a depression scale to reflect the racism and psychosocial factors contributing to depression in African Americans. African Americans are less likely to receive consistent quality care and evidence-based treatment guidelines (i.e., medication therapy or psychotherapy) and less frequently included in research studies. Tools for assessing depression need to be culturally sensitive. Also, healthcare professionals need to be aware of cultural factors when conducting assessments and obtaining a medical history and physical. When prescribing psychotropic medications, clients need adequate assessment and an accurate diagnosis to receive the appropriate medication. Also, clients need an accurate diagnosis when providing culturally competent therapy. If depression is adequately identified in African Americans, health providers will accurately diagnose depression and provide culturally competent treatment.","PeriodicalId":334876,"journal":{"name":"Issues and Development in Health Research Vol. 2","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134131317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Infanticide in South Africa: A Case Study 南非杀婴案:个案研究

Issues and Development in Health Research Vol. 2 Pub Date : 2021-08-07 DOI: 10.9734/bpi/idhr/v2/3326f

L. Bergh

引用次数: 0

Association of High-sensitivity C-Reactive Protein Level with Central Obesity of the Children: A Case Study in a Tertiary Care Hospital of Bangladesh 高敏c反应蛋白水平与儿童中心性肥胖的关系:孟加拉国一家三级医院的案例研究

Issues and Development in Health Research Vol. 2 Pub Date : 2021-08-07 DOI: 10.9734/bpi/idhr/v2/2867f

D. Biswas, Md Moshiur Rahman, F. Sharmin, I. Jahan, A. Roy, S. Begum

{"title":"Association of High-sensitivity C-Reactive Protein Level with Central Obesity of the Children: A Case Study in a Tertiary Care Hospital of Bangladesh","authors":"D. Biswas, Md Moshiur Rahman, F. Sharmin, I. Jahan, A. Roy, S. Begum","doi":"10.9734/bpi/idhr/v2/2867f","DOIUrl":"https://doi.org/10.9734/bpi/idhr/v2/2867f","url":null,"abstract":"Background: Obesity is an exaggeration of everyday adiposity. Central weight problems in children has multiplied than standard adiposity now a days, which isn't robotically measured in medical practice. Adipose tissue contributes to the secretion of some of inflammatory cytokines which stimulate the manufacturing of high-touchy C-reactive protein (hs–CRP) via way of means of the liver. The take a look at changed into finished to look the affiliation of hs–CRP degree with crucial weight problems in Bangladeshi children.\u0000Methods: A total of 110 obese children aged between 10 to 18 years with BMI (ge) 95th centile and age and sex matched 55 non-obese children with BMI (ge) 5th to < 85th centile according to Centers for Disease Control and Prevention (CDC) growth chart were selected. A structured questionnaire was prepared taking into account demographic and clinical parameters. The hs-CRP were estimated in study subjects and then correlated to central obesity by waist height ratio (WHtR).\u0000Results: The prevalence central obesity was 45.5% by WHtR and raised hs-CRP levels was 46.4% in obese children. About 62% of obese children had central obesity who had raised hs-CRP level (ge) 2 mg/L (high risk), which showed significant positive correlation with WHtR and was significantly raised in obese children.\u0000Conclusions: A high proportion of central obesity was observed in obese children who had raised hs-CRP level, suggesting that it might be useful to assess future metabolic and cardiovascular complication.","PeriodicalId":334876,"journal":{"name":"Issues and Development in Health Research Vol. 2","volume":"1058 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123156331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Taboos, Traditional Practices and Beliefs Affecting Pregnancy and Childbirth in Ohangwena, Oshana and Oshikoto Region: A Rural Placement Experience of 2016 University of Namibia Fourth Year Nursing Oshakati Campus, Namibia Ohangwena、oshaana和Oshikoto地区影响怀孕和分娩的禁忌、传统习俗和信仰:2016年纳米比亚大学Oshakati校区四年级护理的农村安置经验

Issues and Development in Health Research Vol. 2 Pub Date : 2021-08-07 DOI: 10.9734/bpi/idhr/v2/11218d

Ester Mulenga, S. A. David, Lucia Ndahambelela Pinehas

引用次数: 0

Investigating the Potential Beneficial Effects of Native Banana Starch on Glycemia and Insulin Resistance in Obese Non-Diabetic Women 研究天然香蕉淀粉对肥胖非糖尿病女性血糖和胰岛素抵抗的潜在有益作用

Issues and Development in Health Research Vol. 2 Pub Date : 2021-08-07 DOI: 10.9734/bpi/idhr/v2/1808c

J. Ble-Castillo, María A. Aparicio-Trápala, A. Gómez-Vázquez, A. Rodríguez-Hernández, J. Méndez, I. Juárez-Rojop, H. Aguilar-Mariscal, J. C. Díaz-Zagoya

{"title":"Investigating the Potential Beneficial Effects of Native Banana Starch on Glycemia and Insulin Resistance in Obese Non-Diabetic Women","authors":"J. Ble-Castillo, María A. Aparicio-Trápala, A. Gómez-Vázquez, A. Rodríguez-Hernández, J. Méndez, I. Juárez-Rojop, H. Aguilar-Mariscal, J. C. Díaz-Zagoya","doi":"10.9734/bpi/idhr/v2/1808c","DOIUrl":"https://doi.org/10.9734/bpi/idhr/v2/1808c","url":null,"abstract":"Several studies have shown that life-style changes can help reduce the risk of diabetes. The purpose of this study was to assess the effects of native banana starch (NBS) on glycemic control and insulin resistance in comparison with metformin (MF) in non-diabetic obese women. Forty participants 20-45 years of age, HOMA- IR (ge)2.5 were randomly assigned to two groups of 20 subjects each. During an eight-week period, one group received NBS 30g/day and the other MF 850 mg/day. Fasting glycemia was reduced by either four weeks NBS or four weeks MF treat-ment (week 0 vs week 4, p<0.05). After NBS and MF treatments, fasting insulin and HOMA-IR values decreased gradually, reaching statistical significance after eight weeks (week 0 vs week 8, p<-0.05). The 30 and 60min insulin AUCs after eight weeks NBS supplementation tended to be lower in comparison to 30 and 60min insulin AUCs at baseline. There were no differences in HOMA-IR response between treatments after four or eight weeks. Data show that NBS supplementation has beneficial effects in reducing fasting glucose and insulin resistance in a group of obese women, and it may represent a low-cost and easily accessible alternative for preventing complications in the obese population.","PeriodicalId":334876,"journal":{"name":"Issues and Development in Health Research Vol. 2","volume":"232 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115300422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determination of ctDNA, Targeted Therapies and Immunotherapy in Non-small-cell Lung Cancer 非小细胞肺癌的ctDNA测定、靶向治疗和免疫治疗

Issues and Development in Health Research Vol. 2 Pub Date : 2021-08-07 DOI: 10.9734/bpi/idhr/v2/3337f

Chennianci Zhu, Weihao Zhuang, Limin Chen, Wenyu Yang, W. Ou

{"title":"Determination of ctDNA, Targeted Therapies and Immunotherapy in Non-small-cell Lung Cancer","authors":"Chennianci Zhu, Weihao Zhuang, Limin Chen, Wenyu Yang, W. Ou","doi":"10.9734/bpi/idhr/v2/3337f","DOIUrl":"https://doi.org/10.9734/bpi/idhr/v2/3337f","url":null,"abstract":"Non-small-cell lung cancer (NSCLC), a subtype of lung cancer, is one of the leading causes of cancer death in both men and women around the world. Circulating tumour DNA (ctDNA), tyrosine kinase inhibitors (TKIs), and immunotherapy have transformed our understanding of NSCLC and its treatment, from diagnosis to targeted NSCLC therapeutics. Quantifying ctDNA is convenient and precise, making clinical decisions easier. TKI-based targeted therapy and immunotherapy have also enhanced the quality of life of NSCLC patients. This article gives an update on ctDNA technologies and their implications for therapeutic options, including medications targeting the epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) with TKIs such as osimertinib and lorlatinib, the emergence of various resistance mechanisms, the control of programmed cell death-1 (PD- 1), programmed cell death ligand-1 (PD-L1), and cytotoxic T-lymphocyte antigen-4 (CTLA-4) by immune checkpoint inhibitors (ICIs) in immunotherapy and the blood tumor mutational burden (bTMB) calculated by ctDNA assay as a novel biomarker for immunotherapy. NSCLC patients, on the other hand, nevertheless confront numerous hurdles. To produce more effective medications or therapies to treat NSCLC, additional research and trials are needed.","PeriodicalId":334876,"journal":{"name":"Issues and Development in Health Research Vol. 2","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127137922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Study on Coronavirus and Nigerian Population; the Realities with Medical Laboratory Services 冠状病毒与尼日利亚人群的关系研究医疗化验服务的现实

Issues and Development in Health Research Vol. 2 Pub Date : 2021-08-07 DOI: 10.9734/bpi/idhr/v2/11147d

U. Obeta, O. Ejinaka, N. Etukudoh, C. R. Ikeagwulonu, E. Agbo, I. R. Jwanse

{"title":"A Study on Coronavirus and Nigerian Population; the Realities with Medical Laboratory Services","authors":"U. Obeta, O. Ejinaka, N. Etukudoh, C. R. Ikeagwulonu, E. Agbo, I. R. Jwanse","doi":"10.9734/bpi/idhr/v2/11147d","DOIUrl":"https://doi.org/10.9734/bpi/idhr/v2/11147d","url":null,"abstract":"Coronavirus (COVID-19) pandemic has challenged the health system of various countries with developed technologies and those with little or no technology in medical laboratory services, Nigeria for example. The quest to curb the pandemic is paramount and the inclusion of medical laboratory component is germane toward bringing COVID-19 to a halt. The medical laboratory services has improved from 5 to 78 centers between February, 2020 and April, 2021 which is commendable. This chapter explored the laboratory services in Nigeria in relationship with the population using 2016 National Bureau of Statistics (NBS) population size and Nigeria center for disease control (NCDC) COVID-19 fact sheet of May 2, 2021. The analysis presents federal capital territory (FCT) Abuja as epicenter of COVID-19 and not Lagos as made popular by NCDC in consideration of population, number of testing and COVID-19 cases. The COVID-19 cases in Nigeria may be skewed to the proximity of medical laboratory services. The reality shows that less than 1% of the current population of Nigeria at May 2021, has been tested for COVID-19. Therefore, it is suggestive to expand the medical laboratory services to all local government areas in Nigeria starting with Cross River, Jigawa, Kano and Kogi states that are still lagging behind in their number of testing.","PeriodicalId":334876,"journal":{"name":"Issues and Development in Health Research Vol. 2","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128998990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Environmental Protection and Safety during Covid-19 Era 新冠肺炎时代的环境保护与安全

Issues and Development in Health Research Vol. 2 Pub Date : 2021-08-07 DOI: 10.9734/bpi/idhr/v2/11440d

N. K. Kumar, S. Naik, C. Priya, Pavithra Prabakaran, B. S. Annapoorna, Ravi Kumar

引用次数: 0