高敏c反应蛋白水平与儿童中心性肥胖的关系:孟加拉国一家三级医院的案例研究

D. Biswas, Md Moshiur Rahman, F. Sharmin, I. Jahan, A. Roy, S. Begum
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引用次数: 1

摘要

背景:肥胖是对日常肥胖的夸大。如今,儿童的中心体重问题已经比标准肥胖增加了好几倍,而在医疗实践中,肥胖并不是通过机器来测量的。脂肪组织有助于一些炎性细胞因子的分泌,这些细胞因子通过肝脏刺激高敏感c反应蛋白(hs-CRP)的产生。该研究对孟加拉国儿童hs-CRP水平与关键体重问题的关系进行了研究。方法:选取BMI为\(\ge\) 95百分位的10 ~ 18岁肥胖儿童110例,年龄和性别符合美国疾病控制与预防中心(CDC)生长图表BMI为\(\ge\) 5 ~ < 85百分位的非肥胖儿童55例。考虑到人口统计学和临床参数,准备了一份结构化问卷。在研究对象中估计hs-CRP,然后通过腰高比(WHtR)与中心性肥胖相关。结果:中枢性肥胖患病率为45.5% by WHtR and raised hs-CRP levels was 46.4% in obese children. About 62% of obese children had central obesity who had raised hs-CRP level \(\ge\) 2 mg/L (high risk), which showed significant positive correlation with WHtR and was significantly raised in obese children.Conclusions: A high proportion of central obesity was observed in obese children who had raised hs-CRP level, suggesting that it might be useful to assess future metabolic and cardiovascular complication.
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association of High-sensitivity C-Reactive Protein Level with Central Obesity of the Children: A Case Study in a Tertiary Care Hospital of Bangladesh
Background: Obesity is an exaggeration of everyday adiposity. Central weight problems in children has multiplied than standard adiposity now a days, which isn't robotically measured in medical practice. Adipose tissue contributes to the secretion of some of inflammatory cytokines which stimulate the manufacturing of high-touchy C-reactive protein (hs–CRP) via way of means of the liver. The take a look at changed into finished to look the affiliation of hs–CRP degree with crucial weight problems in Bangladeshi children. Methods: A total of 110 obese children aged between 10 to 18 years with BMI \(\ge\) 95th centile and age and sex matched 55 non-obese children with BMI \(\ge\) 5th to < 85th centile according to Centers for Disease Control and Prevention (CDC) growth chart were selected. A structured questionnaire was prepared taking into account demographic and clinical parameters. The hs-CRP were estimated in study subjects and then correlated to central obesity by waist height ratio (WHtR). Results: The prevalence central obesity was 45.5% by WHtR and raised hs-CRP levels was 46.4% in obese children. About 62% of obese children had central obesity who had raised hs-CRP level \(\ge\) 2 mg/L (high risk), which showed significant positive correlation with WHtR and was significantly raised in obese children. Conclusions: A high proportion of central obesity was observed in obese children who had raised hs-CRP level, suggesting that it might be useful to assess future metabolic and cardiovascular complication.
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