Azerbaijan Journal of Cardiovascular Surgery最新文献

{"title":"The protective effect of naringenin on ciprofloxacin-induced cardiovascular toxicity in rats","authors":"Z. Ulutas, Sigbetullah Kurutkan, O. Ozhan, A. Yıldız, Ahmet Ulu, Leyla Buyukkorkmaz, N. Vardı, B. Ateş, H. Parlakpınar","doi":"10.5455/azjcvs.2023.07.010","DOIUrl":"https://doi.org/10.5455/azjcvs.2023.07.010","url":null,"abstract":"Aim: Ciprofloxacin (CIPRO) is an antibiotic in the quinolone group. It can exert cardiotoxic effects on the cardiovascular system through potential arrhythmic and oxidative stress. Naringenin (NRG) is a flavonoid compound found in various plant sources. It may protect the heart by lowering oxidative stress and inflammation. In this study, protective effects of NRG against CIPRO-induced cardiotoxicity was explored.\u0000Material and Methods: Thirty-two adult male Sprague-Dawley rats were divided into four groups by simple randomization: Control, CIPRO (50 mg/kg CIPRO intraperitoneally (i.p.) twice a day for 7 days), NRG (25 mg/kg NRG oral gavage (p.o.), 28 days), and NRG+CIPRO (25 mg/kg NRG p.o. for 28 days, 50 mg/kg CIPRO i.p. twice a day from the 22nd day). Data on heart rate, blood pressure (BP), and electrocardiography (ECG) were recorded. The samples (heart and descending aorta) were prepared for histopathology and biochemical analysis. Malondialdehyde (MDA) and total glutathione (tGSH) levels, as well as superoxide dismutase (SOD) activity were evaluated in the heart tissue.\u0000Results: The CIPRO group showed histopathological abnormalities such as infiltration and interstitial oedema. In the NRG+CIPRO group, infiltration was significantly reduced. In the NRG group, SOD activity greatly increased, while in the NRG+CIPRO group, tGSH level significantly increased. The control, CIPRO, and NRG+CIPRO groups showed significantly higher systolic and mean BP measurements than the NRG group. In comparison to the CIPRO and control groups, the QT interval was longer in the NRG group.\u0000Conclusion: NRG can reduce CIPRO-induced cardiac damage in rats by increasing antioxidant enzymes and decreasing oxidative stress. With our histopathological evaluation, we have shown that CIPRO-induced cardiotoxicity may be ameliorated by pretreatment with NRG. NRG may also be effective in BP regulation. It should be kept in mind it is important to use NRG with caution and at appropriate doses, as it may prolong the QT interval.","PeriodicalId":334840,"journal":{"name":"Azerbaijan Journal of Cardiovascular Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116086976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are calcium antagonists necessary to all patients with radial artery during off-pump coronary surgery?","authors":"M. Şahin, Ertan Piri, Sukru Tekindur, E. Kuralay","doi":"10.5455/azjcvs.2023.06.08","DOIUrl":"https://doi.org/10.5455/azjcvs.2023.06.08","url":null,"abstract":"We have made distal radial artery pressure measurement and compared it to another preoperatively cannulated radial artery pressure in order to evaluate the necessity of calcium channel blockers during and after off-pump surgery. If there was more than 20 mmHg gradients between two arms we decided to use calcium channel blockers. Significant pressure gradient (>20 mmHg) was detected in only two percent of our patients.","PeriodicalId":334840,"journal":{"name":"Azerbaijan Journal of Cardiovascular Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128785803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative approach to radial artery patency","authors":"M. Şahin, Ertan Piri, Sukru Tekindur, E. Kuralay","doi":"10.5455/azjcvs.2023.06.07","DOIUrl":"https://doi.org/10.5455/azjcvs.2023.06.07","url":null,"abstract":"Aim: Visual estimates of the severity of coronary stenosis are frequently very inaccurate. Angiography is inaccurate in assessing the functional significance of a coronary stenosis. Severity of stenosis in the native coronary artery is critical for both the short and long-term patency of the radial artery (RA), because of the potentially negative effects of competitive flow when the stenosis is below 70%.\u0000Material and Methods: A one hundred patients were selected. Radial artery is used for all patients during off-pump surgery. After all distal anastomoses are done and the systolic blood pressure reached over 100 mmHg, we have made arterial pressure measurement from the proximal side of radial artery graft. Both radial artery pressure and aortic pressure were recorded instantaneously. Systemic arterial pressure measurements are done from ascending aorta. \u0000Results: Serial postoperative coronary angiographies were performed at the first six postoperative months. We have detected ten radial artery graft occlusions and string sign. Five right coronary artery, four circumflex artery, and one diagonal artery radial artery grafts occluded. The percentage of systolic aortic and coronary pressure measurement (Ao/C-s%) on occluded graft patients was changed from 81 to 97. Percentage of diastolic aortic and coronary pressure measurement (Ao/C-d%) was changed from 83 to 90. Percentage of mean aortic and coronary pressure measurement (Ao/C-m%) was changed from 84 to 95.\u0000Conclusion: We concluded that; we can predict of radial artery prognosis based on the severity degree of coronary artery stenosis. We have found ten radial artery grafts occluded. However the patients are completely asymptomatic because of functionally insignificant lesions despite these lesions are considered visually significant on coronary angiogram. Unfortunately ten radial artery measurements are not enough for establishing a reliable cut-off value. We need more studies for creating a cut-off value determination.","PeriodicalId":334840,"journal":{"name":"Azerbaijan Journal of Cardiovascular Surgery","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123882801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clamp-induced carotid artery dissection during carotid endarterectomy","authors":"M. Şahin, E. Kuralay","doi":"10.5455/azjcvs.2022.08.015","DOIUrl":"https://doi.org/10.5455/azjcvs.2022.08.015","url":null,"abstract":"Clamp-induced internal carotid artery dissection can develop during carotid endarterectomy surgery. If it is not noticed, serious complications such as acute occlusion of the carotid artery in the early period and false aneurysm formation in the late period may develop. Inadequate back-flow and circumferential halo around the distal internal carotid artery may the predictor of injury during carotid artery surgery.","PeriodicalId":334840,"journal":{"name":"Azerbaijan Journal of Cardiovascular Surgery","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127604254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CABG outcomes in patients with postinfarctional ventricular septal rupture","authors":"Ramil A. Aliyev","doi":"10.5455/azjcvs.2022.07.012","DOIUrl":"https://doi.org/10.5455/azjcvs.2022.07.012","url":null,"abstract":"Aim: Postinfarctional ventricular septal rupture (Post MI VSR) is the most fatal complication of the myocardial infarction. The mortality rate in modern and in-time surgical management is varying between 10 and 40%; the survival rate is 88% in the first year. The issue of CABG (coronary artery by-pass grafting) is still the subject of great discussion. In order to clarify this issue, we decided to analyze the short- and long-term outcomes of CABG in our patients with Post MI VSR. \u0000Material and Methods: In our research we analyzed 90 patients with IHD (ischemic heart disease), complicated with Post-MI IVS rupture (Post -MI IVSR). Most of the patients with Post MI VSR were over 60 years old. The Post MI VSR within first days after acute myocardial infarction (AMI) was detected in 10 patients; up to 3 days – in 6 patients; up to 7 days – in 3 patients; from 7 to 29 days – in 4 patients. The time of IVS rupture after AMI was varying from 1 to 29 days (5.5±7.6 дней). All patients were distributed into groups depending on the hospitalization time after AMI. \u0000Out of 83 patients underwent reconstruction after Post MI VSR, 79 (95.2%) required CABG. Two- or three-vessel lesions were detected in 67 (80.7%) patients. Cumulative mortality in CABG group was 19.7%, whereas in the group without accompanied CABG – 20%. The long-term outcomes were followed from 1- to 8 years, averagely in 18 patients (28.6%). \u0000Results: The decompensation of heart failure and relapse of coronary symptoms during follow-up up to 3 years was observed in 6 (33.3%) patients, during follow-up from 3 to 8 years – in 3 (25%) out of 12 patients. The repeated revascularization was conducted in 5 patients. \u0000Conclusion: Our results are showing the benefits of CABG in patients with Post MI VSR, which requires mandatory coronary angiography in pre-op period.","PeriodicalId":334840,"journal":{"name":"Azerbaijan Journal of Cardiovascular Surgery","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124361047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Chronic Venous Disease in primary care centers in Azerbaijan: the VEINSCOPE study","authors":"Farhad Aghayev","doi":"10.5455/azjcvs.2022.07.010","DOIUrl":"https://doi.org/10.5455/azjcvs.2022.07.010","url":null,"abstract":"Aim: CVD is a chronic disorder that substantially changes the quality of life for the patient since the first symptomatic stages. The effect of CVD in the general population is often undervalued and not well detected by health systems. The aim of this study was to update the information on the prevalence of CVD and its stages in accordance with CEAP classification and evaluate the treatment status of CVD patients and the tactics and steps of GPs undertaken in order to manage these patients.\u0000Material and Methods: This cross-sectional multicenter study was performed in primary care centers in which sequential patients searching medical help, regardless of reason, were enrolled. The study included 3249 patients. Data were collected by the use of a questionnaire and clinical examination.\u0000Results: The prevalence of CVD (CEAP categories C0s–C6) was 48.5%. Only 26.9% of the patients had advised with their physicians because of their venous problems in the lower extremities. 30.8% of the patients had received either oral treatment or combination of oral and topical treatments for the given symptoms. Only 5.4% of the cases were redirected to the specialist.\u0000Conclusion: Chronic venous disease is extremely prevalent among patients examined at primary care clinics in Azerbaijan particularly in women and elderly patients. Redirection to a specialist is uncommon.","PeriodicalId":334840,"journal":{"name":"Azerbaijan Journal of Cardiovascular Surgery","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127486831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep wound infection on the sternum after open-heart surgery","authors":"Faig Mirzazada, E. Hasanov","doi":"10.5455/azjcvs.2020.1.1.5","DOIUrl":"https://doi.org/10.5455/azjcvs.2020.1.1.5","url":null,"abstract":"Open-heart surgery is usually performed through median sternotomy, as first described by Milton in 1897. A rare but serious complication associated with this approach is the development of a deep sternal wound infection (DSWI), which has a 4% incidence of occurrence after cardiac surgery. The development of a sternal wound infection often has a late onset and is usually detected only after discharge. DSWI can cause a high morbidity rate of up to 50%, with a prolonged hospital stay and an increased cost of care. In acute stages, sternal collapse and deep mediastinitis can often result in a functional disorder of the organ, which, if not treated adequately, may lead to the patient’s death. Chronic infections are usually associated with chronic draining sinus tracts, osteomyelitis, and costochondritis, which can affect the patient’s quality of life. Early detection and aggressive treatment with debridement, drainage, and immediate wound closure using various muscle flaps are necessary to prevent the development of sternal wound infection. Sternal stability is also an important factor in surgery.","PeriodicalId":334840,"journal":{"name":"Azerbaijan Journal of Cardiovascular Surgery","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134181473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between minimal invasive thoracotomy and standard median sternotomy for repair of atrial septal defects","authors":"A. Aliyev","doi":"10.5455/azjcvs.2022.12.025","DOIUrl":"https://doi.org/10.5455/azjcvs.2022.12.025","url":null,"abstract":"<jats:p />","PeriodicalId":334840,"journal":{"name":"Azerbaijan Journal of Cardiovascular Surgery","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134539853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Native valve endocarditis of aortic and mitral valve involving left coronary artery ostium and interventricular septum: Medical and surgical therapy","authors":"Ziya Shahaliyev, Anar Amrah, V. Mammadov, Aytaj Ismayilzada","doi":"10.5455/azjcvs.2021.04.05","DOIUrl":"https://doi.org/10.5455/azjcvs.2021.04.05","url":null,"abstract":"Infective endocarditis (IE) is an infection of the inner lining of the heart muscle (endocardium) caused by bacteria, fungi, or germs that enter through the bloodstream. Despite improvements in its management, IE remains associated with high mortality and severe complications. The management of IE is multidisciplinary and is comprised of cardiologists, intensive care physicians, and cardiac surgeons. IE involving coronary ostium is very rare and sometimes such cases can cause acute coronary syndrome or sudden cardiac death. In this article, we report the case of a 48-year-old man who developed infective endocarditis involving aortal and mitral valves, as well as interventricular septum and left main coronary ostium as a result of Enterococcus faecalis. The vegetation on the ostium of the left main coronary artery has not caused coronary obstruction, but because of possible embolic events, all vegetation has been cleaned and a more appropriate repairment technique has been applied. Patient treated with vancomycin, rifampicin, and gentamicin before surgical replacement of damaged valves. We have performed aortic valve replacement, and mitral and tricuspidal valve repairment procedures. Beside of that vegetations on the interventricular septum and on the coronary ostium were extracted and damage repaired. The patient has discharged from the hospital on day 5 postoperatively without any signs of IE. Conclusion E. faecalis-associated infective endocarditis should be included in the differential diagnosis of valvular vegetation, especially in patients with a rapidly progressing clinical course. A multidisciplinary approach to IE is critical for improving the life quality of patients by reducing mortality and preventing complications. This case also highlights the importance of collecting blood cultures before initiation of antibiotic treatment.","PeriodicalId":334840,"journal":{"name":"Azerbaijan Journal of Cardiovascular Surgery","volume":"51 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133350876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis of coarctation with hypoplastic aorta arch","authors":"Y. Sinelnikov, E. Hasanov, Faig Mirzazada, I. Soynov","doi":"10.5455/azjcvs.2020.1.1.6","DOIUrl":"https://doi.org/10.5455/azjcvs.2020.1.1.6","url":null,"abstract":"The tactics of active surgical intervention in the diagnosis of coarctation of the aorta with hypoplasia concominant arc in the early stages generally leads to significant improvement in long-term results after surgery. This decrease in the number of cases of recoarctation and persistent increase in blood pressure leads to systemic hypertension. Currently there are many techniques that allow to precisely diagnose the stage of hypoplasia of the aortic arch. This allows you to plan the tactics of surgical treatment of the aortic arch in young patients.","PeriodicalId":334840,"journal":{"name":"Azerbaijan Journal of Cardiovascular Surgery","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114714831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}