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Phase 1 Safety and Pharmacodynamic Results of VRDN-001, a Full Antagonist Antibody to the Insulin-Like Growth Factor-1 Receptor (IGF-1R) in Development for Thyroid Eye Disease (TED) (P3-9.007) 针对胰岛素样生长因子-1受体(IGF-1R)的全拮抗剂VRDN-001用于甲状腺眼病(TED)的1期安全性和药效学结果
Sunday, April 23 Pub Date : 2023-04-25 DOI: 10.1212/wnl.0000000000202052
A. She, Barrett Katz, R. Summerfelt, Denis J. O'Shaughnessy, B. Dickinson, K. Foster, V. Bedian
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引用次数: 0
Critically-Elevated Interleukin-6 (IL-6): A Prognostic Biomarker for Post-Acute Sequelae of COVID-19 (PASC)? (P2-7.001) 急性升高的白细胞介素6 (IL-6): COVID-19急性后后遗症(PASC)的预后生物标志物?(p2 - 7.001)
Sunday, April 23 Pub Date : 2023-04-25 DOI: 10.1212/wnl.0000000000203337
Ronak D. Trivedi, M. Jaffry, Iqra Faiz, Muhammed Ors, K. Mandava, K. Jaffry, A. Shaikh, Pratibha Surathi, T. Tofade, Evan Huff, S. Redko, N. Souayah
{"title":"Critically-Elevated Interleukin-6 (IL-6): A Prognostic Biomarker for Post-Acute Sequelae of COVID-19 (PASC)? (P2-7.001)","authors":"Ronak D. Trivedi, M. Jaffry, Iqra Faiz, Muhammed Ors, K. Mandava, K. Jaffry, A. Shaikh, Pratibha Surathi, T. Tofade, Evan Huff, S. Redko, N. Souayah","doi":"10.1212/wnl.0000000000203337","DOIUrl":"https://doi.org/10.1212/wnl.0000000000203337","url":null,"abstract":"","PeriodicalId":334567,"journal":{"name":"Sunday, April 23","volume":"48 8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123176080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overview of the Safety Profile from Efgartigimod Clinical Trials in Participants with Diverse IgG-Mediated Autoimmune Diseases (P1-5.001) 依加替莫德在多种igg介导的自身免疫性疾病患者临床试验中的安全性概述(P1-5.001)
Sunday, April 23 Pub Date : 2023-04-25 DOI: 10.1212/wnl.0000000000201746
K. Gwathmey, C. Broome, M. Goebeler, H. Murai, Z. Bata-Csorgo, A. Newland, P. Ulrichts, R. Kerstens, J. Guptill, Sofiane Agha, M. Jiang, J. Howard
{"title":"Overview of the Safety Profile from Efgartigimod Clinical Trials in Participants with Diverse IgG-Mediated Autoimmune Diseases (P1-5.001)","authors":"K. Gwathmey, C. Broome, M. Goebeler, H. Murai, Z. Bata-Csorgo, A. Newland, P. Ulrichts, R. Kerstens, J. Guptill, Sofiane Agha, M. Jiang, J. Howard","doi":"10.1212/wnl.0000000000201746","DOIUrl":"https://doi.org/10.1212/wnl.0000000000201746","url":null,"abstract":"","PeriodicalId":334567,"journal":{"name":"Sunday, April 23","volume":"89 10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124158270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microvascular Cerebral Blood Flow Monitoring Detects Response to Intrathecal Nicardipine Treatment for Vasospasm (S4.005) 微血管脑血流监测检测鞘内尼卡地平治疗血管痉挛的反应(S4.005)
Sunday, April 23 Pub Date : 2023-04-25 DOI: 10.1212/wnl.0000000000203890
E. Sathialingam, K. Cowdrick, T. Urner, A. Liew, E. Sigman, F. Akbik, O. Samuels, P. Kandiah, E. Buckley, O. Sadan
{"title":"Microvascular Cerebral Blood Flow Monitoring Detects Response to Intrathecal Nicardipine Treatment for Vasospasm (S4.005)","authors":"E. Sathialingam, K. Cowdrick, T. Urner, A. Liew, E. Sigman, F. Akbik, O. Samuels, P. Kandiah, E. Buckley, O. Sadan","doi":"10.1212/wnl.0000000000203890","DOIUrl":"https://doi.org/10.1212/wnl.0000000000203890","url":null,"abstract":"","PeriodicalId":334567,"journal":{"name":"Sunday, April 23","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124219348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post Ictal Generalized EEG suppression, Not Sleep State, is Associated with Peri-Ictal Respiratory Disturbances in Stereoelectroencephalography Recorded Perisylvian Seizures (S6.007) 立体脑电图记录的发作期癫痫发作与发作后全身性脑电图抑制而非睡眠状态相关(S6.007)
Sunday, April 23 Pub Date : 2023-04-25 DOI: 10.1212/wnl.0000000000202987
L. Mora-Muñoz, N. Andrews, Matheus Araujo, L. Aboussouan, W. Bingaman, Lu Wang, M. Grigg-Damberger, Nancy Foldvary Schaefer
{"title":"Post Ictal Generalized EEG suppression, Not Sleep State, is Associated with Peri-Ictal Respiratory Disturbances in Stereoelectroencephalography Recorded Perisylvian Seizures (S6.007)","authors":"L. Mora-Muñoz, N. Andrews, Matheus Araujo, L. Aboussouan, W. Bingaman, Lu Wang, M. Grigg-Damberger, Nancy Foldvary Schaefer","doi":"10.1212/wnl.0000000000202987","DOIUrl":"https://doi.org/10.1212/wnl.0000000000202987","url":null,"abstract":"","PeriodicalId":334567,"journal":{"name":"Sunday, April 23","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124221897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wernicke’s Encephalopathy Preceded by COVID-19 Infection: A Case Report (P2-7.006) 新冠病毒感染前韦尼克脑病1例报告(P2-7.006)
Sunday, April 23 Pub Date : 2023-04-25 DOI: 10.1212/wnl.0000000000202463
A. Volski, Victor Wang, Satabdi Chakrabarti Pulakanti, A. Dolla
{"title":"Wernicke’s Encephalopathy Preceded by COVID-19 Infection: A Case Report (P2-7.006)","authors":"A. Volski, Victor Wang, Satabdi Chakrabarti Pulakanti, A. Dolla","doi":"10.1212/wnl.0000000000202463","DOIUrl":"https://doi.org/10.1212/wnl.0000000000202463","url":null,"abstract":"","PeriodicalId":334567,"journal":{"name":"Sunday, April 23","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117353026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral Subdural Hematoma, The Cause or Consequence (P1-4.005) 双侧硬膜下血肿的原因和后果(P1-4.005)
Sunday, April 23 Pub Date : 2023-04-25 DOI: 10.1212/wnl.0000000000203212
Narmada Mannem, Nicholas B Yelverton
{"title":"Bilateral Subdural Hematoma, The Cause or Consequence (P1-4.005)","authors":"Narmada Mannem, Nicholas B Yelverton","doi":"10.1212/wnl.0000000000203212","DOIUrl":"https://doi.org/10.1212/wnl.0000000000203212","url":null,"abstract":"","PeriodicalId":334567,"journal":{"name":"Sunday, April 23","volume":"431 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116004664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Global Prevalence and Incidence of Amyotrophic Lateral Sclerosis: A Systematic Review (P2-5.023) 肌萎缩性侧索硬化症的全球患病率和发病率:系统综述(P2-5.023)
Sunday, April 23 Pub Date : 2023-04-25 DOI: 10.1212/wnl.0000000000203202
C. Wolfson, Danielle E Gauvin, F. Ishola, M. Oskoui
{"title":"The Global Prevalence and Incidence of Amyotrophic Lateral Sclerosis: A Systematic Review (P2-5.023)","authors":"C. Wolfson, Danielle E Gauvin, F. Ishola, M. Oskoui","doi":"10.1212/wnl.0000000000203202","DOIUrl":"https://doi.org/10.1212/wnl.0000000000203202","url":null,"abstract":"","PeriodicalId":334567,"journal":{"name":"Sunday, April 23","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116277771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histopathological Analysis of Cerebral Microvasculature Pathology with Alzheimer’s Disease Neuropathological Changes: An Autopsy Study (P3-6.007) 阿尔茨海默病脑微血管病理的组织病理学分析神经病理改变:尸检研究(P3-6.007)
Sunday, April 23 Pub Date : 2023-04-25 DOI: 10.1212/wnl.0000000000202911
Yuan Cao, Mei-Ying Huang, Chen-Hui Mao, Xue Wang, Yuan-yuan Xu, Xiaojing Qian, Chao Ma, Wen-Ying Qiu, Yi-Cheng Zhu
{"title":"Histopathological Analysis of Cerebral Microvasculature Pathology with Alzheimer’s Disease Neuropathological Changes: An Autopsy Study (P3-6.007)","authors":"Yuan Cao, Mei-Ying Huang, Chen-Hui Mao, Xue Wang, Yuan-yuan Xu, Xiaojing Qian, Chao Ma, Wen-Ying Qiu, Yi-Cheng Zhu","doi":"10.1212/wnl.0000000000202911","DOIUrl":"https://doi.org/10.1212/wnl.0000000000202911","url":null,"abstract":"","PeriodicalId":334567,"journal":{"name":"Sunday, April 23","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116414234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Thymoma-Associated Idiopathic Inflammatory Myopathy and Myasthenia Gravis (P1-5.009) 胸腺瘤相关特发性炎性肌病合并重症肌无力1例(P1-5.009)
Sunday, April 23 Pub Date : 2023-04-25 DOI: 10.1212/wnl.0000000000203054
Chelsea Schmoll, Stefanie J. Rodenbeck
{"title":"A Rare Case of Thymoma-Associated Idiopathic Inflammatory Myopathy and Myasthenia Gravis (P1-5.009)","authors":"Chelsea Schmoll, Stefanie J. Rodenbeck","doi":"10.1212/wnl.0000000000203054","DOIUrl":"https://doi.org/10.1212/wnl.0000000000203054","url":null,"abstract":"","PeriodicalId":334567,"journal":{"name":"Sunday, April 23","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123448156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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