Annals of Child Neurology最新文献_第2页

Correlation between Persistent Serum Lactate Elevation and Brain Magnetic Resonance Imaging Abnormalities in Children with Status Epilepticus 癫痫状态儿童持续性血清乳酸升高与脑磁共振成像异常之间的相关性

Annals of Child Neurology Pub Date : 2023-12-07 DOI: 10.26815/acn.2023.00206

P. Gunawan, Riza Noviandi, Sunny Mariana Samosir

{"title":"Correlation between Persistent Serum Lactate Elevation and Brain Magnetic Resonance Imaging Abnormalities in Children with Status Epilepticus","authors":"P. Gunawan, Riza Noviandi, Sunny Mariana Samosir","doi":"10.26815/acn.2023.00206","DOIUrl":"https://doi.org/10.26815/acn.2023.00206","url":null,"abstract":"Purpose: This study was conducted to evaluate the correlation between persistent serum lactate elevation and brain magnetic resonance imaging (MRI) in children with status epilepticus (SE). Methods: In this prospective analytical study, serum lactate levels were measured 24 hours after episodes of SE, and brain MRI was performed within 7 to 14 days after SE termination. MRI abnormalities were classified as acute encephalopathy (AE) grade I to III. The Kruskal-Wallis test was utilized for statistical analysis. Results: The study included 42 participants with SE, of whom 85.70% were boys, with a mean age of 4.94 years. Viral encephalitis was the most common diagnosis, accounting for 47.60% of cases. Elevated serum lactate levels were detected in 71.40% of patients, and approximately 47.60% exhibited abnormal MRI findings consistent with AE grade I. The median serum lactate levels for AE grades I, II, and III were 1.50, 3.10, and 0.78 mmol/L, respectively. Two patients died, and 66.70% experienced neurologic sequelae. A significant correlation ( P =0.021) was observed between persistent serum lactate elevation and abnormal brain MRI findings. Conclusion: In children with SE, AE grade I was the most common neuroimaging pattern observed, and persistently elevated serum lactate level was correlated with abnormal brain MRI findings.","PeriodicalId":33305,"journal":{"name":"Annals of Child Neurology","volume":"56 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138593041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of Knowledge, Attitudes, and Practices of Parents/Caregivers Towards Migraine in Children: A Cross-Sectional Observational Study 评估父母/照顾者对儿童偏头痛的知识、态度和实践:一项横断面观察研究

Annals of Child Neurology Pub Date : 2023-11-02 DOI: 10.26815/acn.2023.00262

Rahul Sinha, Ankit Kumar Meena, Maneesh Uniyal, Sonali Singh, Ashish Upadhyay

{"title":"Assessment of Knowledge, Attitudes, and Practices of Parents/Caregivers Towards Migraine in Children: A Cross-Sectional Observational Study","authors":"Rahul Sinha, Ankit Kumar Meena, Maneesh Uniyal, Sonali Singh, Ashish Upadhyay","doi":"10.26815/acn.2023.00262","DOIUrl":"https://doi.org/10.26815/acn.2023.00262","url":null,"abstract":"Purpose This study aimed to evaluate the knowledge, attitudes, and practices (KAP) of parents or caregivers of children suffering from migraines at a tertiary care center in North India. Methods We conducted a cross-sectional study involving 100 parents or caregivers, using convenience sampling. A 20-item questionnaire was administered in English and also translated into the local language (Hindi). The study included children with migraines who visited the pediatric outpatient department within a 6-month period (December 2022 to May 2023). Results Over 60% of caregivers were aware of the chronic nature of the illness, its triggering factors, the role of family history, and the importance of lifestyle modifications. However, only 46% understood the pathophysiology of the illness, and 53% were aware of the medication used for childhood migraines. More than 85% of caregivers believed that recurrent headaches necessitate a doctor's consultation, may require regular visits for optimal treatment, and were willing to alter their child's lifestyle to prevent headaches. However, a significant percentage of caregivers (47%) practised self-medication for their children's headaches. Most caregivers believed that lifestyle modifications and avoiding triggers were the best treatments for migraines. There were significant associations (P<0.05) between the level of education and responses to questions related to migraine definition, prophylaxis, treatment, investigations, lifestyle modifications, and screen time. Conclusion Most participants were well-educated on migraine, and their KAP regarding migraine prevention and treatment were generally adequate. However, the practice of self-medication without professional guidance is a significant concern. Keywords: Migraine disorders; Cross-sectional studies; Caregivers; Health knowledge, attitudes, practice; Life style","PeriodicalId":33305,"journal":{"name":"Annals of Child Neurology","volume":"33 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135876281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation between Diagnostic Magnetic Resonance Imaging Criteria and Cerebrospinal Fluid Pressure in Pediatric Idiopathic Intracranial Hypertension 小儿特发性颅内高压诊断磁共振成像标准与脑脊液压力的相关性研究

Annals of Child Neurology Pub Date : 2023-10-31 DOI: 10.26815/acn.2023.00241

Behnam Beizaei, Farrokh Seilanian Toosi, Yousef Shahmoradi, Javad Akhondian, Farah Ashrafzadeh, Mehran Beiraghi Toosi, Shima Imannezhad, Alireza Kooshki, Ehsan Hassan Nejad, Asma Payandeh, Nahid Tavakkolizadeh, AmirAli Moodi Ghalibaf, Narges Hashemi

{"title":"Correlation between Diagnostic Magnetic Resonance Imaging Criteria and Cerebrospinal Fluid Pressure in Pediatric Idiopathic Intracranial Hypertension","authors":"Behnam Beizaei, Farrokh Seilanian Toosi, Yousef Shahmoradi, Javad Akhondian, Farah Ashrafzadeh, Mehran Beiraghi Toosi, Shima Imannezhad, Alireza Kooshki, Ehsan Hassan Nejad, Asma Payandeh, Nahid Tavakkolizadeh, AmirAli Moodi Ghalibaf, Narges Hashemi","doi":"10.26815/acn.2023.00241","DOIUrl":"https://doi.org/10.26815/acn.2023.00241","url":null,"abstract":"Purpose Idiopathic intracranial hypertension (IIH) is a clinical syndrome that mimics brain tumors with increased intracranial pressure. The present study is designed to investigate the diagnostic criteria of magnetic resonance imaging (MRI) and the severity of cerebrospinal fluid (CSF) pressure to understand the relationship and frequency of these criteria with the level of CSF pressure. Methods The present cross-sectional study was conducted on children diagnosed with IIH between the years 2011 and 2020, who were admitted to the pediatric neurology department of Ghaem Hospital, Mashhad, Iran. Clinical manifestations and imaging findings of the patients were recorded through a checklist. Results Forty-nine patients were included in the study; 27 (55.1%) were male, and 22 (44.9%) were female. The average CSF pressure was 40.64Â±20.63 cmH2O. The mean diameter distension of the perioptic subarachnoid space was 6.02Â±1.21 mm. Six (10.8%) patients had unilateral transverse sinus stenosis with an average CSF pressure of 20.47Â±36.80 cmH2O and 11 (21.4%) patients had bilateral transverse sinus stenosis with an average pressure of 48.22Â±21.04 cmH2O. In 22 (44.89%) patients, flattening of the posterior globe with the CSF pressure of 48.80Â±17.94 cmH2O was reported. Twenty-four (49%) patients had optic nerve tortuosity, with an average CSF pressure of 46.52Â±20.33 cmH2O. Among the diagnostic criteria, the pressure had a significant relationship with the flattening of the posterior globe (P<0.022). Conclusion Since MRI is a non-invasive method for examining IIH, the findings of this study may aid in diagnosing and monitoring these patients. Keywords: Magnetic resonance imaging; Cerebrospinal fluid; Pseudotumor cerebri; Pediatrics","PeriodicalId":33305,"journal":{"name":"Annals of Child Neurology","volume":"83 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135813890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lessons Learned from the Point-of-Care Use of a Facial Analysis Technology 即时使用面部分析技术的经验教训

Annals of Child Neurology Pub Date : 2023-10-01 DOI: 10.26815/acn.2023.00227

Jon Soo Kim, Hansol Ko, Hyewon Woo, Won Seop Kim

引用次数: 0

Characteristics of Epilepsy in Children with Cerebral Palsy: A Single Tertiary Center Study 脑瘫患儿癫痫特征:单三级中心研究

Annals of Child Neurology Pub Date : 2023-10-01 DOI: 10.26815/acn.2023.00220

Hyein Yeo, Ji Yoon Han, Jee Min Kim

{"title":"Characteristics of Epilepsy in Children with Cerebral Palsy: A Single Tertiary Center Study","authors":"Hyein Yeo, Ji Yoon Han, Jee Min Kim","doi":"10.26815/acn.2023.00220","DOIUrl":"https://doi.org/10.26815/acn.2023.00220","url":null,"abstract":"Purpose: The aim of this study was to describe the characteristics of epilepsy in cerebral palsy (CP) patients and identify risk factors for epilepsy and drug-resistant epilepsy.Methods: CP patients aged 18 years old or younger who visited the pediatric neurology department and/or rehabilitation department of a tertiary care hospital between January 2016 and December 2022 with a minimum follow-up period of 2 years were included. Demographic and clinical data, seizure characteristics, brain imaging, electroencephalography, and genetic evaluation results were reviewed retrospectively.Results: Among 268 patients included in this study, 36.9% had epilepsy and 10.8% had drug-resistant epilepsy. Asphyxia (29.3%), hemorrhage, infarction, and brain infection (25.3%) were associated with epilepsy. Epileptic CP patients were more likely to experience neonatal seizures (18.2% vs. 4.1%, <i>P</i><0.001) and febrile seizures (12.1% vs. 7.1%, <i>P</i>=0.02) than non-epilepsy CP patients. The most common cerebral subtype in patients with epilepsy was spastic quadriplegia (59.6%). Epilepsy patients were more severely impaired in gross motor function, with worse intellectual disability. Patients with macrocephaly or cerebral malformation were more likely to have drug resistance. Valproate (51.7% and 25.7%) and levetiracetam (41.4% and 25.7%) were the two most commonly used antiseizure medications, both in monotherapy and polytherapy.Conclusion: A history of asphyxia, febrile seizure, neonatal seizure, spastic quadriplegia, more severely impaired gross motor function, and intellectual disability were found to be risk factors for epilepsy. Further research with prospective data collection to develop a model for predicting seizures or epilepsy in CP patients is needed.","PeriodicalId":33305,"journal":{"name":"Annals of Child Neurology","volume":"161 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135274308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Profound Biotinidase Deficiency: A Rare but Treatable Inborn Error of Metabolism in a Neonate with Recurrent Seizures 深度生物素酶缺乏:一种罕见但可治疗的先天性代谢错误在新生儿复发性癫痫发作

Annals of Child Neurology Pub Date : 2023-09-18 DOI: 10.26815/acn.2023.00192

Ye-Na Kim, Mi-Sun Yum, Min-Jee Kim, Tae-Sung Ko

引用次数: 0

Efficacy of High-Dose Steroid Therapy on Bilateral Total Visual Loss in a Patient with Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes (MELAS) 大剂量类固醇治疗线粒体脑肌病、乳酸酸中毒和卒中样发作(MELAS)患者双侧全视力丧失的疗效

Annals of Child Neurology Pub Date : 2023-09-11 DOI: 10.26815/acn.2023.00213

Seok-Jin Lee, Ji-Hoon Na, Young-Mock Lee

引用次数: 0

A Case of Cerebellar Infarction While Swimming in a Child Diagnosed by Ataxia and Gait Disturbance 共济失调和步态障碍诊断儿童游泳时小脑梗死1例

Annals of Child Neurology Pub Date : 2023-09-05 DOI: 10.26815/acn.2023.00185

Young Eun Kim, Sungwon Byun

引用次数: 0

Brain Magnetic Resonance Imaging in Indonesian Patients with Cerebral Palsy 印尼脑瘫患者的脑磁共振成像

Annals of Child Neurology Pub Date : 2023-09-05 DOI: 10.26815/acn.2023.00171

P. Gunawan, R. Noviandi, Sunny Mariana Samosir

{"title":"Brain Magnetic Resonance Imaging in Indonesian Patients with Cerebral Palsy","authors":"P. Gunawan, R. Noviandi, Sunny Mariana Samosir","doi":"10.26815/acn.2023.00171","DOIUrl":"https://doi.org/10.26815/acn.2023.00171","url":null,"abstract":"Purpose: Cerebral palsy (CP) is a neurological health problem that affects children around the world and warrants particular attention. Magnetic resonance imaging (MRI) can be used to visualize brain disorders, as it provides a clear view of the brain’s anatomy, including the location of any damage or structural abnormalities. The objective of this study was to obtain a detailed MRI representation of patients with CP. Methods: This study employed a retrospective design involving the examination of medical records. It included CP patients aged between 1 and 16 years who had undergone brain MRI examinations. The Gross Motor Function Classification System scale was used to classify limitations in functional motor ability among these patients. The brain MRI results were categorized as either normal or abnormal. Results: Of 60 CP cases, 50% were classified as severe, with the remaining cases considered mild to moderate. Epilepsy was present in 66.7% of patients with severe CP. The most common type of CP, among both mild-to-moderate and severe cases, was quadriplegia. Gray matter lesions on brain MRI were more common in severe than mild-to-moderate cases, while vascular insult lesions and brain malformations were less frequent. A significant difference was observed in the severity of CP when a gray matter lesion was present on MRI. Conclusion: Most children with CP exhibited abnormal results on brain MRI. Lesions of the white and gray matter were the most frequently observed. MRI plays a crucial role in understanding the underlying pathological brain abnormalities in CP.","PeriodicalId":33305,"journal":{"name":"Annals of Child Neurology","volume":"182 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41281542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Celebrating the 30th Anniversary of the Korean Society for Child Neurology 庆祝韩国儿童神经学会成立30周年

Annals of Child Neurology Pub Date : 2023-08-31 DOI: 10.26815/acn.2023.00255

Y. Kwon

引用次数: 0