N. Meida, Ahmad Ikliluddin, Yunani Setyandriana, Vania Rahmawati
{"title":"The Pattern of Intraocular Pressure After Phacoemulsification Surgery In Senile Cataract","authors":"N. Meida, Ahmad Ikliluddin, Yunani Setyandriana, Vania Rahmawati","doi":"10.18196/mmjkk.v23i1.15570","DOIUrl":"https://doi.org/10.18196/mmjkk.v23i1.15570","url":null,"abstract":"Phacoemulsification is a surgical procedure for cataracts, which can increase intraocular pressure (IOP) and cause blindness due to glaucoma. It was known that the pattern of IOP changes after phacoemulsification surgery in senile cataracts. This study was an observational analytic study without a control group design. The study population was male and female senile cataract patients over 40 years of age who underwent phacoemulsification surgery at Kebumen Eye Centre Clinic in 2020. Intraocular pressure measurements using a Noncontact Tonometry by a nurse were carried out before surgery (D-0) and postoperatively on day 2 (D-2), day 9 (D-9), day 16 (D-16), and day- 23 (D-23). The data were analyzed using the Friedman test followed by the Post Hoc LSD test. The Friedman test results showed significant differences (p 0.05) in the IOP measurement at D-0, D-2, D-9, D-16, and D-23. Wilcoxon post hoc test showed IOP measurements on D-2 increased and then decreased normally. There was a change in the IOP pattern after phacoemulsification surgery, in which the IOP increased significantly on D-2 and then decreased normally.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90927048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luh Komang Diah Lakhsmi Paramita, S. Priyambodo, R. Cholidah
{"title":"Self-Management and Quality of Life in Diabetic Type II Patients at Mataram University Hospital","authors":"Luh Komang Diah Lakhsmi Paramita, S. Priyambodo, R. Cholidah","doi":"10.18196/mmjkk.v23i1.16320","DOIUrl":"https://doi.org/10.18196/mmjkk.v23i1.16320","url":null,"abstract":"Type 2 diabetes mellitus (DM) is the community's most common metabolic disease, indicated by increased blood glucose. Patients with type 2 DM cannot be cured but can be controlled by self-management. Self-management improves the quality of life (QoL) by increasing the quality of metabolic control and reducing the risk of hospitalization and mortality complications of type 2 DM. This study aims to examine the relationship between self-management and the QoL among patients with type 2 DM at the Mataram University Hospital. This study used a cross-sectional analytic method, and the population included outpatients with type 2 DM in Mataram University Hospital. This study employed 40 people selected by the consecutive sampling method and got interviewed to fill out the Diabetes Self-Management Questionnaires (DSMQ) and Asian Diabetes Quality of Life (Asian DQOL) questionnaires. The data analysis used the Spearman statistical test. The majority of the self-management respondents were good (87.5%), and the QoL (95%). The results obtained a p-value of 0.000 (p0.05), indicating a significant relationship between self-management and the QoL of type 2 DM patients in Mataram University Hospital. This result showed that the better the self-management of type 2 DM patients is, the better their QoL will be.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86239578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Putri Nadia Ramadhani, I. Kurniati, Maya Dian Rakhmawatie
{"title":"Antimicrobial Activity of Pecut Kuda Leaf Extract (Stachytarpheta jamaicensis (L. Vahl) against Mycobacterium smegmatis","authors":"Putri Nadia Ramadhani, I. Kurniati, Maya Dian Rakhmawatie","doi":"10.18196/mmjkk.v23i1.15599","DOIUrl":"https://doi.org/10.18196/mmjkk.v23i1.15599","url":null,"abstract":"Mycobacterium smegmatis infrequently causes infection, but it is easy to be pathogenic in immunosuppressed patients. Many reported that M. smegmatis resistance to several antibiotics became an impetus for searching for new antimicrobials. Therefore, this study aims to prove the effect of Pecut Kuda leaf extract (Stachytarpheta jamaicensis (L.) Vahl) on the growth of M. smegmatis mc2 155. This research is an experimental study with a post-test control group design. The susceptibility test was carried out using the two-fold microdilution method and resazurin staining. The concentration of Pecut Kuda leaf ethanol extract was prepared in the concentration range of 10000.0 – 625.0 µg/ml. Phytochemical analysis of the content of saponins, tannins, flavonoids, and alkaloids was also carried out on Pecut Kuda leaf ethanol extract. Pecut Kuda leaf ethanol extract can inhibit the growth of M. smegmatis with a minimum inhibitory concentration (MIC) of 5000 µg/ml (very weak activity) because, at the highest concentration of 10000 µg/ml, M. smegmatis still cannot be killed. Furthermore, Pecut Kuda leaf ethanol extract contains saponins, tannins, flavonoids, and alkaloids which are known to have antibacterial activity. However, further evaluation is needed to maximize the antibacterial activity of Pecut Kuda leaf extract, for example, by fractionating the extract.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90516240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"UJI DAYA HAMBAT PERASAN DAUN KIRINYUH (Chromolaena odorata L.) PADA BAKTERI YANG DIISOLASI DARI PENDERITA JERAWAT","authors":"Armilah Armilah, Mujahidah Basarang, Tuty Widyanti, Anita Anita","doi":"10.53861/jmed.v7i2.349","DOIUrl":"https://doi.org/10.53861/jmed.v7i2.349","url":null,"abstract":"Kirinyuh (Chromolaena odorata) merupakan tanaman yang memiliki kandungan senyawa kimia seperti flavonoid, saponin, alkaloid, tannin, steroid dan fenol yang berfungsi sebagai antibakteri. Daun kirinyuh dapat digunakan sebagai antibakteri untuk menghambat pertumbuhan Propionibacterium acne dan Staphylococcus aureus yang merupakan bakteri penyebab jerawat. Penelitian ini bertujuan untuk mengetahui daya hambat perasan daun kirinyuh (Chromolaena odorata) terhadap pertumbuhan bakteri yang diisolasi dari penderita jerawat. Penelitian ini menggunakan metode difusi cakram. Perasan daun kirinyuh dibuat menjadi 4 konsentrasi yaitu 25%, 50%, 75%, dan 100%. Sebagai kontrol positif digunakan yaitu tetrasiklin. Dilakukan pengujian pada Staphylococcus aureus yang diisolasi dari jerawat. Hasil pengujian yang telah dilakukan dengan menggunakan perasan daun kirinyuh konsentrasi yaitu 25%, 50%, 75% dan 100% didapatkan hasil pengukuran diameter zona hambat di sekitar bakteri uji adalah 0 mm. Berdasarkan penelitian maka dapat disimpulkan bahwa perasan daun kirinyuh tidak dapat menghambat pertumbuhan bakteri yang diisolasi dari penderita jerawat.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"155 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73477107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Suardi, Dewi Arisanti, Hasnah Hasnah, Kardina Widanda Kai
{"title":"DETEKSI C-REACTIVE PROTEIN (CRP) PADA PENDERITA DIABETES MELITUS (DM) DI RSUD LABUANG BAJI KOTA MAKASSAR","authors":"S. Suardi, Dewi Arisanti, Hasnah Hasnah, Kardina Widanda Kai","doi":"10.53861/jmed.v7i2.325","DOIUrl":"https://doi.org/10.53861/jmed.v7i2.325","url":null,"abstract":"Diabetes melitus merupakan penyakit yang dapat menyebabkan terjadinya hiperglikemia, yang terjadi akibat kekurangan secara relatif dari kerja atau sekresi hormon insulin. Faktor penyebabnya yaitu glukosa yang menumpuk dalam darah sehingga dapat masuk ke dalam sel. Penderita diabtetes melitus memiliki sistem imun yang rendah, sehingga mudah terkena infeksi. Hal ini diperkuat dengan meningkatnya marker inflamasi. C- Reactive Protein (CRP) merupakan salah satu penanda inflamasi akut yang berasal dari hati dan sering ditemukan pada penderita diabetes melitus dan penyakit kardiovaskular. CRP akan meningkat tinggi pada proses peradangan dan rusaknya jaringan. CRP dapat menjadi marker yang cukup sensitif untuk mendeteksi terdapatnya inflamasi yang berhubungan progress dari aterosklerosis. Penelitian ini bertujuan untuk mengetahui gambaran CRP pada penderita diabetes melitus di RSUD Labuang Baji Kota Makassar. Jenis penelitian ini, yaitu observasi laboratorik, dengan teknik pengambilan sampel random sampling. Dengan menggunakan metode pemeriksaan yaitu metode uji aglutinasi pasif, dilakukan pada 10 sampel serum. Hasil penelitian diperoleh dari 10 sampel, sebanyak 8 sampel positif tejadi aglutinasi dan 2 sampel negatif tidak terjadi aglutinasi. Dengan demikian, dapat disimpulkan bahwa penderita diabetes melitus beresiko memicu peningkatan kadar CRP.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"118 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76995152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Fatmawati, S. Suardi, Dina Diyanah, Andi Ulfa Tenri Pada
{"title":"KEJADIAN INFEKSI JAMUR PENYEBAB TINEA PEDIS TERKAIT HIGIENITAS DI LINGKUNGAN PADAT PENDUDUK KAMPUNG NELAYAN","authors":"A. Fatmawati, S. Suardi, Dina Diyanah, Andi Ulfa Tenri Pada","doi":"10.53861/jmed.v7i2.348","DOIUrl":"https://doi.org/10.53861/jmed.v7i2.348","url":null,"abstract":"Kelompok jamur dermatofita merupakan penyebab terjadinya infeksi tinea pedis yang terdapat pada sela-sela jari kaki dan telapak kaki yang ditandai dengan adanya maserasi berupa kulit putih dan rapuh. Kondisi tempat tinggal di lingkungan kampung nelayan sangat padat penduduk, sehingga potensi kontak langsung kulit dan lingkungan yang kurang bersih dapat menjadi salah satu faktor penyebab tinea pedis. Penelitian ini bertujuan untuk mengetahui kejadian infeksi jamur penyebab tinea pedis terkait higienitas pada masyarakat di daerah padat penduduk lingkungan kampung nelayan di kecamatan Tallo, Kota Makassar. Jenis penelitian adalah observasi laboratorik dengan teknik pengambilan sampel secara purposive sampling, dengan metode identifikasi secara pengamatan langsung dari kultur isolat jamur Hasil penelitian pada 10 sampel didapatkan 4 sampel positif jamur penyebab tinea pedis yaitu Trichophyton rubrum dan Trichophyton mentagrophytes. Sedangkan 6 sampel lainnya ditemukan jamur lain yaitu Candida albicans. Tingkat kejadian infeksi jamur penyebab tinea pedis ini terkait dengan kurang terjaganya higienitas diri dan lingkungan pada kawasan padat penduduk kampung nelayan.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89459733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Correlation between Various Types of Antihypertensive Drugs and the Incidence of Acute Stroke","authors":"Athiyya Salma Hamida, Tri Wahyuliati","doi":"10.18196/mmjkk.v23i1.13955","DOIUrl":"https://doi.org/10.18196/mmjkk.v23i1.13955","url":null,"abstract":"Stroke is the second leading cause of death and the third leading cause of disability, whose incidence increase with hypertension. Various antihypertensives are used as secondary therapy for stroke. However, the effectiveness of each drug is still debated. This study aims to determine the correlation between various types of antihypertensive drugs on the incidence of acute stroke. This research is a cross-sectional study. Inclusion criteria included hypertensive patients who had used antihypertensive drugs for at least a year and were aged 36. We included 78 subjects, 47 men and 31 women. The drugs were ACEI + CCB (13), ARB (8), ARB + CCB (22), and CCB (35). The subject had an ischemic stroke (8) and a hemorrhagic stroke (1). The logistic regression test showed ACEI + CCB as a reference category. The result consecutively showed ARB (OR, 4.95; CI, 0.72 to 33.89; p = 0.103), CCB (OR, 2.61; CI, 0.39 to 17.01; p = 0.317), and ARB + CCB (OR, 2.36; CI, 0.19 to 29.75; p = 0.507). The antihypertensive drugs had no significant correlation with the incidence of acute stroke. It indicated that stroke risk was not triggered by antihypertensive and could effectively control hypertension and protect patients against stroke","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91277431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siti Munawaroh, Y. Hastami, A. Suwandono, H. Hartono, A. Probandari
{"title":"Reading Holy Qur’an to Improve Verbal Fluency in Elderly","authors":"Siti Munawaroh, Y. Hastami, A. Suwandono, H. Hartono, A. Probandari","doi":"10.18196/mmjkk.v23i1.15160","DOIUrl":"https://doi.org/10.18196/mmjkk.v23i1.15160","url":null,"abstract":"The high prevalence of dementia that impairs verbal fluency has been a global source of concern. As a result, strategies for preserving or improving verbal fluency in the elderly are required. A neuroplasticity-based reading program has been shown to improve verbal fluency. This study aims to ascertain whether reading the Holy Qur'an has an effect on an older adult's ability to communicate fluently. It is an experimental study with a quasi-experimental design with pretest-posttest control groups. This study sampled 22 elderly individuals with the following criteria: age greater than 60 years, ability to speak and read the Holy Qur'an, a Mini-Mental State Examination (MMSE) score greater than 24, absence of psychiatric disorders, absence of head trauma, and absence of neurological disease. The intervention group read the Quran for two weeks, while the control group did not. Both groups were measured for Verbal fluency at the beginning and after the intervention. There were significant differences in post-test phonemic scores between the control group (CG) and the intervention group (IG) (p=0.019). Meanwhile, there was no significant difference in semantic score in all groups (p0.852). Reading the Holy Qur’an activity intervention for two weeks affected verbal fluency in the elderly by increasing phonemic but not semantic scores.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74930192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cutaneous Manifestations of Breast Cancer Patients in Combination with Capecitabine and Lapatinib Chemotherapy","authors":"Nita Damayanti Sulistianingrum","doi":"10.18196/mmjkk.v23i1.12276","DOIUrl":"https://doi.org/10.18196/mmjkk.v23i1.12276","url":null,"abstract":"The combination of chemotherapy with lapatinib and capecitabine in human epidermal growth factor receptor 2 (HER2) positive breast cancer is quite effective. The combination of these two agents increases the risk of dermatological toxicities. A woman, 38 years old, HER2 positive breast cancer with a combination of chemotherapy agents between lapatinib and capecitabine gives an overview of skin toxicities such as acneiform eruptions, palmar-plantar erythrodysesthesia (PPE), and paronychia. Therapy, in this case, aims at clinical improvement. The combination of lapatinib and capecitabine has a side effect profile like each drug. Combined use of the two agents increases the incidence of skin side effects, including acneiform eruptions, PPE, and paronychia, compared to monotherapy. Early awareness of the side effects of chemotherapeutic agents is needed for early treatment to prevent the worsening of the condition and discontinuation of chemotherapeutic agents due to drug side effects.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85989156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"ANALISIS PEMAHAMAN MAHASISWA FARMASI MENGENAI PENGGUNAAN\u0000VITAMIN SEBAGAI UPAYA PENINGKATAN IMUNITAS DI MASA PANDEMI\u0000COVID-19","authors":"Baiq Bismiranti Haris, Zulfiana Fitrianingrum Annas, Nur Amalina Sabdarrifa, Candra Eka Puspitasari","doi":"10.35990/mk.v5n4.p401-411","DOIUrl":"https://doi.org/10.35990/mk.v5n4.p401-411","url":null,"abstract":"Semenjak awal kemunculannya hingga ditetapkan sebagai pandemic, berbagai upaya telah\u0000dilakukan oleh World Health Organization (WHO) serta pemerintah untuk menekan\u0000pelonjakan jumlah kasus Corona Virus Disease-19 (COVID-19), salah satunya dengan\u0000mengonsumsi vitamin karena beberapa vitamin diduga memiliki efek sebagai\u0000imunomodulator. Penelitian ini dilakukan dengan tujuan mengkaji pengetahuan mahasiswa\u0000Farmasi Universitas Mataram (UNRAM) mengenai penggunaan vitamin di masa pandemi\u0000COVID-19 serta jenis vitamin yang biasa dikonsumsi oleh mahasiswa dalam rangka\u0000meningkatkan imunitas diri. Penelitian ini dilakukan dengan desain cross sectional. Data\u0000diambil dengan menggunakan kuisioner daring berupa google form. Data yang didapat\u0000kemudian diolah menggunakan Microsoft excel. Hasil dari penelitian ini yaitu rata-rata\u0000responden memeroleh nilai sangat baik dikarenakan lebih dari 85% responden menjawab\u0000pertanyaan secara tepat serta sebanyak 99,4% responden menilai bahwa menjaga imunitas\u0000adalah penting. Adapun jenis vitamin yang biasa dikonsumsi oleh mahasiswa Farmasi\u0000UNRAM yaitu vitamin C, vitamin A, dan kombinasi dari vitamin A, B, C, D, E, K.\u0000Pengetahuan mahasiswa Farmasi UNRAM mengenai penggunaan vitamin dalam\u0000meningkatkan imunitas berada dalam kriteria sangat baik serta vitamin C merupakan jenis\u0000vitamin yang paling banyak dikomsumsi oleh mahasiswa Farmasi.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78004286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}