Jurnal Profesi Medika最新文献_第3页

Current Approach of Small Field Electron Beam for Head and Neck Cases 头颈部病例小场电子束的当前方法

Jurnal Profesi Medika Pub Date : 2023-06-14 DOI: 10.33533/jpm.v17i1.5848

S. Ulya, D. Ryangga, W. Wibowo, N. Nasution, S. Pawiro

{"title":"Current Approach of Small Field Electron Beam for Head and Neck Cases","authors":"S. Ulya, D. Ryangga, W. Wibowo, N. Nasution, S. Pawiro","doi":"10.33533/jpm.v17i1.5848","DOIUrl":"https://doi.org/10.33533/jpm.v17i1.5848","url":null,"abstract":"Regarding the increasing use of small-field photons in clinical treatment, in this study, we investigate the use of small-field electron beams in clinical treatment. This study aimed to evaluate small-field electron beam dosimetry of the nasopharyngeal, thyroid, and ethmoid sinus carcinoma cases. Dose measurement was done using EBT3 film. In nasopharyngeal cases with a homogenous area and irregular surface, the dose discrepancies for 6 MeV energy were unpredictable except for the 5×5 cm2 field size. For all energies in 5×5 cm2 field size, the dose discrepancies were less than 3%. In these cases, we found that a smaller electron beam field will increase the percentage of the dose discrepancy. This is caused by the effect of the lateral scatter disequilibrium in a small field electron beam. For ethmoid sinus cases, dose discrepancy depends on the field size and inhomogeneity of bone and tissue organ. Based on the evaluation of doses on the spinal cord, chiasm, and larynx (OAR), it can be seen that these organs received a very small dose. From this result, a small field electron beam is recommended for cases with a homogeneous target. However, in cases with a heterogenous target, further investigation is needed.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42488823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of Zingiber Aromaticum Vaal. With Zerumbone and Its Biological Activity : A Literature Review 姜香料协会。与Zerumbone及其生物活性:文献综述

Jurnal Profesi Medika Pub Date : 2023-06-14 DOI: 10.33533/jpm.v17i1.5816

R. Murwanti, Rimadani Pratiwi, A. P. Gani

引用次数: 0

Association of SMAD3 Gene rs12901499 Variation with Knee Osteoarthritis in Indonesian Aged Women SMAD3基因rs12901499变异与印尼老年妇女膝骨性关节炎的关系

Jurnal Profesi Medika Pub Date : 2023-06-04 DOI: 10.33533/jpm.v17i1.5738

A. Zaki, C. Adhiyanto, L. Hendarmin, Fauzia Ilman Naqiya, Dwi Karni, Zeti Harriyati

{"title":"Association of SMAD3 Gene rs12901499 Variation with Knee Osteoarthritis in Indonesian Aged Women","authors":"A. Zaki, C. Adhiyanto, L. Hendarmin, Fauzia Ilman Naqiya, Dwi Karni, Zeti Harriyati","doi":"10.33533/jpm.v17i1.5738","DOIUrl":"https://doi.org/10.33533/jpm.v17i1.5738","url":null,"abstract":"Small Mother Against Decapentaplegic 3 (SMAD3), an intracellular transducer protein in the TGF-β signaling pathway, has a role in maintaining joint cartilage. Many studies have been conducted to examine the effect of polymorphism in SMAD3 gene with the incidence of osteoarthritis (OA). The objective of this study is to identify the association of SMAD3 gene rs12901499 variation with the incidence of knee OA in Indonesian women. We conducted an analytic cross-sectional design involving 24 knee OA patients and 50 non-OA subjects. The DNA was taken from saliva and genotyped using a kit from Integrated DNA Technologies with the Real Time PCR method. In this study, we found that the GA genotype (heterozygous mutant) of the rs12901499 allele was the allele that most frequently (50%) appeared in knee OA patients as well as non-OA subjects (50%). The G allele frequency was higher than the A allele among all participants. The Chi-Square analysis showed that there was no statistically significant relationship between allele variations in the SMAD3 rs12901499 gene and knee OA (p=1). In conclusion, there was no statistically significant relationship between the rs12901499 genetic variation in the SMAD3 gene and the incidence of knee osteoarthritis in Indonesian aged women.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46320472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Characteristics of Ocular Toxoplasmosis Patients 眼部弓形虫病患者的临床特点

Jurnal Profesi Medika Pub Date : 2023-06-04 DOI: 10.33533/jpm.v17i1.5653

Frashad Fanseca Alvarez, Petty Purwanita, Indri Seta Septadina

{"title":"Clinical Characteristics of Ocular Toxoplasmosis Patients","authors":"Frashad Fanseca Alvarez, Petty Purwanita, Indri Seta Septadina","doi":"10.33533/jpm.v17i1.5653","DOIUrl":"https://doi.org/10.33533/jpm.v17i1.5653","url":null,"abstract":"Toxoplasma gondii infection causes posterior uveitis and blindness. The diagnosis of ocular toxoplasmosis is based on typical clinical findings accompanied by positive anti-Toxoplasma serology. This study aims to see the clinical characteristics of ocular toxoplasmosis patients. Cross-sectional observational descriptive research is done. This study used 2019-2021 medical records from RSUP Dr. Mohammad Hoesin Palembang patients. The highest incidence of ocular toxoplasmosis at RSUP Dr. Mohammad Hoesin Palembang in 2019-2021 occurred in 2021 (54.5%). The most common age range found in this case is the age group of 0-19 years (45.5%) and the majority are women (72.7%). The majority of patients are out of work (45.5%) and live outside Palembang (81.8%). The most lateralization was found in the right eye (63.6%). The most commonly complained clinical symptom is blurred vision (90.9%). Clinical signs were found lesions of retinochoroiditis in the macular (45,5%), in the extramacular (18,2%), chorioretinal scar (90,9%), vitritis (54,5%), decreased visual acuity (100%), and increased IOP (36,4%). Anti-Toxoplasma IgG was found positive in all patients. The highest incidence of ocular toxoplasmosis was found in 2021. The most commonly complained clinical symptom is blurred vision and the most commonly found clinical sign is a decrease in visual acuity. \u0000 ","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43703361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibiogram of Patients With Diabetic Foot at Dr. Soebandi Regional Hospital of Jember, Indonesia 印度尼西亚Jember Dr. Soebandi地区医院糖尿病足患者的抗生素谱

Jurnal Profesi Medika Pub Date : 2023-06-04 DOI: 10.33533/jpm.v17i1.5753

E. Suswati, Habibulloh Mustofa, Bagus Hermansyah, D. Agustina, E. N. Sakinah

{"title":"Antibiogram of Patients With Diabetic Foot at Dr. Soebandi Regional Hospital of Jember, Indonesia","authors":"E. Suswati, Habibulloh Mustofa, Bagus Hermansyah, D. Agustina, E. N. Sakinah","doi":"10.33533/jpm.v17i1.5753","DOIUrl":"https://doi.org/10.33533/jpm.v17i1.5753","url":null,"abstract":"Diabetic foot is a complication of diabetes mellitus that uses antibiotics to control the infection as the primary therapy. This study aimed to determine the type of bacteria and antimicrobial sensitivity patterns in diabetic foot. The samples were taken from the medical records of the patients with diabetic foot, who performed the swab culture and antimicrobial susceptibility testing in the inpatient and outpatient care in dr. Soebandi Regional Hospital. The samples used were the patients diagnosed with diabetic foot from January 1, 2014, to December 31, 2018. The data in this study were univariately analyzed. Forty-three pathogens were isolated from 40 patients with 12 ESBL isolates. The most common bacteria found were Gram-negative (90.7%), including Escherichia coli (33.33%), Klebsiella pneumoniae (12.82%) Pseudomonas aeruginosa (12.82%), Enterobacter cloacae (7.69%) and Proteus mirabilis (7.69%). Then, there were also 9.3% Gram-positive bacteria of all isolates, with Staphylococcus aureus as the most dominant species (50%). The antibiotic antimicrobial susceptibility testing also showed that Imipenem, amikacin, fosfomycin, cefoxitin, and netilmicin were the most sensitive antibiotics. The most common type of bacteria found was Escherichia coli, while the antibiotic still sensitive in most bacteria was imipenem.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42036423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determinants of Integrated Services Post Programme Utilization in Elderly Empowerment in Medan Amplas District 棉兰Amplas地区综合服务项目后方案利用对老年人赋权的决定因素

Jurnal Profesi Medika Pub Date : 2023-06-04 DOI: 10.33533/jpm.v17i1.5843

Ivena Hotmarina Septiani Nainggolan, Fitriani Pramita Gurning

{"title":"Determinants of Integrated Services Post Programme Utilization in Elderly Empowerment in Medan Amplas District","authors":"Ivena Hotmarina Septiani Nainggolan, Fitriani Pramita Gurning","doi":"10.33533/jpm.v17i1.5843","DOIUrl":"https://doi.org/10.33533/jpm.v17i1.5843","url":null,"abstract":"There is an increase in the elderly population at this time, making the morbidity rate in the elderly also increase. In 2021, the number of elderly people who experienced illness in the past month was around 34.48%. Meanwhile, in 2022, the morbidity rate increased to 41.3%, The purpose of this study was to determine the determinants of the use of posyandu programs in empowering the elderly in Harjosari I Village, Medan Amplas District. The method used is a quantitative approach cross-sectional research design by surveying as many as 30 people as representatives of the population by accidental sampling by conducting interviews using online-based questionnaires, after the interview the data was analyzed statistically using univariate, bivariate and multivariate tests with a multi-stage model Analisys model to obtain crude values and adjusted oods ratio with an alpha significance of 5% (p<0.05). The results showed that the greatest influence on the utilization of the posyandu program was a distance of >100 meters with an exp value (B) of 2.56. The conclusion is that overall variables have a significant relationship with the utilization of elderly posyandu services with risks ranging from 1.43 to 2.56 times.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46960377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determinants of Active Aging Affect Healthy Life Expectation 积极老龄化影响健康预期寿命的决定因素

Jurnal Profesi Medika Pub Date : 2023-05-31 DOI: 10.33533/jpm.v17i1.5837

R. Theresa, Marlina Dewiastuti, Melly Kristanti, Cantika Vadia Aqli, Fakultas Kedokteran

{"title":"Determinants of Active Aging Affect Healthy Life Expectation","authors":"R. Theresa, Marlina Dewiastuti, Melly Kristanti, Cantika Vadia Aqli, Fakultas Kedokteran","doi":"10.33533/jpm.v17i1.5837","DOIUrl":"https://doi.org/10.33533/jpm.v17i1.5837","url":null,"abstract":"Life expectancy is an indicator of successful health development. It is estimated the elderly population will increase along with the increase in life expectancy, in 2050 there will be an increase 3 times in the number of elderly from 2013. The increase in the number of elderly raises a health sector complicated problem. The elderly group will experience a decrease in health status either naturally or due to illness. Goals of the health program focus on life expectancy. West Java is the largest proportion with Indramayu a city in West Java that has a target life expectancy that reaches the target. The government's efforts to improve the elderly welfare are realized in various programs so that an increase in the elderly population does not increase health problems. Indicators of elderly health can be measured by active aging (AA).. The determinants of the AA component, which include health and well-being, are indicators for assessing healthy life expectancy in the elderly. Assessment of healthy life expectancy is assessed from several determinants. Assessment of healthy life expectancy can determine health development targets, especially in the elderly. This study associated dietary patterns and smoking habits with increased healthy life expectancy.","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49637929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Therapeutic Communication on the Level of Self-Esteem in the Elderly: A Case Study of the Laut Dendang Village in the Percut Sei Tuan District 治疗性沟通对老年人自尊水平的影响——以打击乐Sei Tuan区Laut Dendang村为例

Jurnal Profesi Medika Pub Date : 2023-05-31 DOI: 10.33533/jpm.v17i1.5501

M. Pasaribu, Zulfahri Lubis, Muhammad Kevin Humala Sakti Siregar, A. Fitria, Amar Ma’ruf

引用次数: 0

Multiple Radiologic Findings in a Simple Blunt Thoracic Trauma 一例单纯钝性胸外伤的多发性放射学表现

Jurnal Profesi Medika Pub Date : 2023-05-03 DOI: 10.33533/jpm.v17i1.5123

P. Sidipratomo, J. Pandelaki, Samuel Widjaja, Jason Jason

引用次数: 0

GAMBARAN DOSIS TERAPI ARIPIPRAZOLE PASIEN SKIZOFRENIA DENGAN POLIMORFISME GEN DRD2 PADA TITIK RS6277 (C957T) RS6277 (C957T)精神分裂症患者多形性基因DRD2治疗剂量(C957T)

Jurnal Profesi Medika Pub Date : 2023-04-05 DOI: 10.32502/sm.v13i2.3825

{"title":"GAMBARAN DOSIS TERAPI ARIPIPRAZOLE PASIEN SKIZOFRENIA DENGAN POLIMORFISME GEN DRD2 PADA TITIK RS6277 (C957T)","authors":"","doi":"10.32502/sm.v13i2.3825","DOIUrl":"https://doi.org/10.32502/sm.v13i2.3825","url":null,"abstract":"Polimorfisme gen C957T merupakan synonymous mutation yang terletak pada pasang basa ke-957 gen DRD2. Terdapat perbedaan konformasi antara mRNA 957T dengan mRNA 957C, yaitu mRNA 957T kurang stabil dan lebih rentan terhadap degradasi. Tujuan penelitian ini untuk menunjukkan gambaran dosis terapi aripiprazole pasien skizofrenia dengan polimorfisme gen DRD2 pada titik rs6277 (C957T). Penelitian ini merupakan penelitian deskriptif dengan menggunakan desain penelitian cross sectional. Analisis data dengan menggunakan analisis univariat untuk mengidentifikasi responden berupa usia, jenis kelamin, polimorfisme gen DRD2, dan dosis terapi aripiprazole. Pengambilan data dilakukan dengan menggunakan data kuesioner untuk mendapatkan data karakteristik responden serta pengambilan sampel darah untuk mendapat data polimorfismen gen DRD2. Responden penelitian ini terdapat 60 orang responden yang memenuhi kriteria. Hasil penelitian ini didapatkan bahwa sebagian besar responden memiliki karakteristik usia 21-39 tahun (65,0%), jenis kelamin laki-laki (71,7%), dosis terapi aripiprazole 10 mg (60,0%), dan alel C (65,0 %) pada polimorfisme gen DRD2 pada titik rs6277 (C957T). Aripiprazole diduga menyebabkan multiplisitas fungsional pada reseptor dopamin D2 jalur pascasinaps, dimana pengikatan preferensial untuk konformasi berbeda dari reseptor D2, untuk mengaktifkan jalur transduksi diferensial sesuai dengan subtipe neuron dimana mereka diekspresikan. Berdasarkan penelitian yang dilakukan maka perlu dilakukan studi lebih lanjut untuk penentuan kadar konsentrasi aripiprazole di dalam darah pasien skizofrenia dan dengan mempertimbangkan lama terapi dengan evaluasi lebih lama","PeriodicalId":33234,"journal":{"name":"Jurnal Profesi Medika","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82709469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0