mjl@ kly@ lTb最新文献

筛选
英文 中文
N-acetyl cysteine’s effect on semen parameters in a sample of Iraqi men with oligoasthenoteratozoospermia n -乙酰半胱氨酸对伊拉克少弱异性精子症患者精液参数的影响
mjl@ kly@ lTb Pub Date : 2022-10-17 DOI: 10.32007/jfacmedbagdad.6431938
Fatima Sinan, Huda I. Al-Qadhi, Baraa A. Al Kareem
{"title":"N-acetyl cysteine’s effect on semen parameters in a sample of Iraqi men with oligoasthenoteratozoospermia","authors":"Fatima Sinan, Huda I. Al-Qadhi, Baraa A. Al Kareem","doi":"10.32007/jfacmedbagdad.6431938","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6431938","url":null,"abstract":"Background: Infertility is recognized as the incapability of infertile couples to become pregnant following one year of unsafe intercourse, with male factors accounting for roughly half of the documented instances. Several reasons for male infertility factors have been reported; however, the actual cause in the majority of cases remains unknown.\u0000Objective: To study prospectively the outcome of N-acetylcysteine on semen parameters in males with oligoasthenoteratozoospermia.\u0000Patient and methods: A total 45 patients with idiopathic oligoasthenoteratozoospermia have received N-acetyl cysteine (NAC) for 12 weeks, their seminal fluid parameters were measured at the baseline and after 12 weeks.\u0000Results: The results showed that after 3 months of NAC treatment, the motility was statistically significantly higher than pre-NAC baseline, with no statistically significant differences in both count and morphology.\u0000Conclusion: These results confirmed that NAC has a positive effect in improving motility in infertile men and thus resulting in better spermatogenesis and sperm function.","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47460298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Quality of life in capecitabine-treated patients with colorectal cancer is affected by their sociodemographic characteristics and their experience of the drug-related adverse effects 卡培他滨治疗的结直肠癌患者的生活质量受到其社会人口学特征和药物相关不良反应经历的影响
mjl@ kly@ lTb Pub Date : 2022-10-17 DOI: 10.32007/jfacmedbagdad.6431970
M. Jabarah
{"title":"Quality of life in capecitabine-treated patients with colorectal cancer is affected by their sociodemographic characteristics and their experience of the drug-related adverse effects","authors":"M. Jabarah","doi":"10.32007/jfacmedbagdad.6431970","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6431970","url":null,"abstract":"Background: Colorectal cancer is the third most prevalent cancer worldwide as 1.80 million new cases of the cancer were diagnosed and 862,000 patients died in 2018. Depending on the stage, upfront surgery is the main form of treatment, followed by adjuvant chemotherapy. Moreover, many drugs are approved by the U.S. Food and Drug Administration to treat Colorectal cancer including Capecitabine. However, during cancer treatment, the measurement of patient-reported symptoms experience and quality of life can provide additional information to evaluate and compare the efficacy and toxicity profiles of the treatments. Despite the importance of patients' quality of life during treatment while they are on anti-cancer treatment, there was no published data in the literature evaluating this vital parameter concerning Iraqi patients receiving anti-cancer drugs, in general, or those on Capecitabine, in particular. Therefore, the aim of current study was to evaluate quality of life of Iraqi patients with colorectal cancer treated with Capecitabine. Methods: A cross-sectional, open-label prospective study was conducted at Al-Amal and Oncology Teaching Hospitals in Baghdad during the period from November 2021 to June 2022. A convenient sampling method was adopted to enrol patients in the current study. Quality of life assessment was performed using the European Organization for Research and Treatment of Cancer quality of life questionnaire (QLQ-C30). Microsoft Excel 2019 and the Statistical Package for the Social Sciences (SPSS, Version 25) were used for data entry and analysis. The descriptive analysis focused on frequencies and percentages. Continuous variables were presented as mean (± Standard Deviation). Categorical data were presented as proportions and the Chi-squared test was used for the difference between two proportions. The level of significance was considered at P≤0.05.\u0000Results: A total of 102 patients were enrolled in the current study. Generalized fatigue was the most common adverse event as it presented in 63.7% of participants. Also, only 6.9% of participants had abnormal renal function tests. In addition, some capecitabine-treated patients had good quality of life, others did not.\u0000Conclusion: The quality of life of capecitabine-treated colorectal cancer patients seems to be sensitive to their sociodemographic characteristics and adverse effects profile of the drug.","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69419714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hypertension Control among Adult Iraqis 成年伊拉克人的高血压控制
mjl@ kly@ lTb Pub Date : 2022-10-17 DOI: 10.32007/jfacmedbagdad.6431935
Nada Abdul Wahhab Mousa, Muna A, Khaleefah, H. J. Al-Badri
{"title":"Hypertension Control among Adult Iraqis","authors":"Nada Abdul Wahhab Mousa, Muna A, Khaleefah, H. J. Al-Badri","doi":"10.32007/jfacmedbagdad.6431935","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6431935","url":null,"abstract":"Background: Hypertension is a chronic illness that affects one billion people both in high and low-income countries and is the most common risk factor for death throughout the world. It is also responsible for stroke, ischemic heart disease, heart, and kidney failure in addition to its huge effect on the economy. Like many developing countries, Iraq is undergoing a transitional epidemiological period with increasing burden of hypertension and its contributing risk factors e.g. unhealthy diet, physical inactivity, obesity, hyperglycemias, hypercholesterolemia, and smoking. In spite of the availability of a screening program for the early detection of hypertension in primary health care centres (PHCCs) little data on hypertension control is available.\u0000Objectives: Assessing blood pressure control rate among Iraqi adults 18 years and older, and identifying the related determinants.\u0000Patients and Methods: The study is derived from the second round of Non-Communicable Diseases Risk Factors STEPS survey Iraq 2016. A cross-sectional survey was performed on households from all Iraqi governorates excluding three governorates suffering instability. A Multi-stage cluster sampling technique for a sample of 4120 Iraqi adults was used. Interviews were held from the first week of November for 20 days using Arabic and Kurdish translated versions of STEPS questionnaire. A total of 4071 residents participated.\u0000Results: the prevalence of hypertension/ high blood pressure was 35.6%. Only 7.9% were under medication and controlled with an evident sex-based difference in favour of women (9.3% vs. 6.6% respectively). Uncontrolled blood pressure increased with age (t=7.4 p=<0.001), and declined with years of education (t= -3.3 p=0.01).  It was significant among subjects with hyper-triglycerides (X²= 4.07 p= 0.044), consumption of salty processed food (X²= 7.35 p= 0.007). Blood pressure was not controlled among those reported being currently on medication (X²= 22.4 p= < 0.001).\u0000Conclusions: Blood pressure control rate is low among Iraqi adults on medical and lifestyle management. Further assessment and strengthening of clinical practice on hypertension management is recommended.","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45858038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The predicting factors of clinical outcomes in patients with COVID-19 in the Kingdom of Saudi Arabia [KSA]: A multi-center cohort study 沙特阿拉伯王国COVID-19患者临床结局的预测因素[KSA]:一项多中心队列研究
mjl@ kly@ lTb Pub Date : 2022-07-24 DOI: 10.32007/jfacmedbagdad.6421907
Janan Alrefaee, Aishah E Albalawi, S. Alanazi, Norah A Althobaiti, H. Daghash, Tharaa Abu Hasb, Mohammad S. Abusuliman
{"title":"The predicting factors of clinical outcomes in patients with COVID-19 in the Kingdom of Saudi Arabia [KSA]: A multi-center cohort study","authors":"Janan Alrefaee, Aishah E Albalawi, S. Alanazi, Norah A Althobaiti, H. Daghash, Tharaa Abu Hasb, Mohammad S. Abusuliman","doi":"10.32007/jfacmedbagdad.6421907","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6421907","url":null,"abstract":"Background: On March 2020, the first case of coronavirus disease-19 was registered in the Kingdom of Saudi Arabia and subsequently the first mortality case. The predicting factors for patients' outcomes are essential to triage patients with COVID-19. This may provide low-cost facilities that help in the fight against the existing global pandemic.   \u0000Objectives: This study aimed to predict hospitalization and death outcomes of COVID-19 patients using the simplest facilities.\u0000Method: The electronic medical records of 280 COVID-19 patients between March 2020 and May 2021 were retrieved from a multi-centre of healthcare facilities across Kingdom of Saudi Arabian cites. All demographic and clinical information were examined to determine predictors and outcomes.\u0000Results: Of the 280 COVID -19 patients enrolled in our study, 14.3% were aged ≥ 66 years and 62.5% were female. The elderly (≥ 66 years, P= 0.000) and male patients (P= 0.001) were significantly hospitalized by COVID -19 than others. Patients with symptoms were hospitalized significantly more than patients without symptoms (P= 0.001). Patients with chronic conditions were hospitalized more frequently (P= 0.001). Hospitalization status also did not differ by smoking. Fever occurred significantly more frequently in patients with one or more chronic diseases (P = 0.000). Elderly (≥ 66 years, P= 0.000) and male patients of COVID -19 (P= 0.022) had significant evidence of association with death outcome than others. Hospitalization status was associated with death (P = 0.000).\u0000Conclusion: This study reported that male gender and advanced age COVID-19 patients are independent predictors for both hospital admission and death outcomes more than others. The COVID-19 patients who complain from symptoms are at risk for hospitalization as well. Additionally, having chronic clinical conditions are predictor factor for hospital admission outcome. Finally, the hospitalized patients of COVID-19 infection are at risk for death outcome.","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45966302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Total Procollagen Type 1 Intact N-terminal Propeptide, C-telopeptide of type 1 collagen, Bone Mineral Density and its Relationship to Body Mass Index in Men with Type 2 Diabetes 男性2型糖尿病患者总前胶原ⅰ型完整n端前肽、ⅰ型胶原c端肽、骨密度及其与体重指数的关系
mjl@ kly@ lTb Pub Date : 2022-07-24 DOI: 10.32007/jfacmedbagdad.6421942
E. Abed, Dr Manal K Rasheed, Dr Khalaf G.Hussein
{"title":"Assessment of Total Procollagen Type 1 Intact N-terminal Propeptide, C-telopeptide of type 1 collagen, Bone Mineral Density and its Relationship to Body Mass Index in Men with Type 2 Diabetes","authors":"E. Abed, Dr Manal K Rasheed, Dr Khalaf G.Hussein","doi":"10.32007/jfacmedbagdad.6421942","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6421942","url":null,"abstract":"Background: Type 2 diabetes negatively affects the biochemical parameters of bone turnover more than obesity and is associated with an increased risk of osteoporosis and fragility fractures. Obesity and type 2 diabetes (T2DM) are linked to increased fracturing risk; however, the effect of obesity on diabetes-related bone deficit is unknown.\u0000Objective: The goal of this research is to compare the indications, bone density, and bone turnover in T2DM men and a control group, and to investigate the effect of body mass index on bone turnover levels.\u0000Subjects, Material and Method: This case-control study was conducted on 120 men whose ages were from 40 - 69 years. They were grouped into two categories: T2DM (n=80) and healthy control (n=40). Serum samples from both groups were analyzed for blood glucose, Calcium and Albumin, by using (Cobas c111), PTH by (Cobas e 411), P1NP and CTX-1 levels in the serum using ELISA kits. Participants underwent (DEXA) measuring Bone Mass Density (BMD) at the lumbar spine.\u0000Results: The control (obese and non-obese) participants had statistically significant higher levels of CTX-1 and P1NP than the patients (obese and non-obese) (P-value = 0.000). There was no significant differences in Spine BMD, T-score (p-value = 0.27 and 0.37 respectively).\u0000Conclusion: Men with T2DM had a low bone turnover level and deteriorated bone quality compared to controls. The obese healthy controls can maintain healthy bone metabolism if T2DM is prevented.\u0000 ","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47610049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Electrophysiological Perspectives of Essential, Enhanced Physiological, and Physiological Tremors 基本震颤、增强震颤和生理震颤的电生理学观点
mjl@ kly@ lTb Pub Date : 2022-07-24 DOI: 10.32007/jfacmedbagdad.6421921
Nawras Sabah najim, Abdulnasir H. Ameer, Azad A. Mohammed
{"title":"The Electrophysiological Perspectives of Essential, Enhanced Physiological, and Physiological Tremors","authors":"Nawras Sabah najim, Abdulnasir H. Ameer, Azad A. Mohammed","doi":"10.32007/jfacmedbagdad.6421921","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6421921","url":null,"abstract":"Abstract: \u0000Background: The most frequent movement issue seen in clinical practice is tremors. It is known as repetitive, involuntary oscillations. The diagnostic process for tremor patients can be time-consuming and complicated, as the identification of “Essential Tremor” and its distinction from other types of tremor.\u0000Objectives: This study aimed to describe the electrophysiological findings of essential, enhanced physiological, and physiological tremors, using surface electromyography and an accelerometer.\u0000Patients and Methods: The study included 24 patients with essential tremors, 10 patients with enhanced physiological tremors, and 10 patients with physiological tremors. We assessed the frequency, amplitude, and muscular contraction pattern of tremors during rest, posture, and a 1 kg load.\u0000 Results: The tremor frequency of essential tremor patients was about 4.2-10.1 Hertz, while enhanced physiological tremor and physiological tremor were increased to 6.1–12.7 Hertz and 5.1-10.2 Hertz, respectively. The essential tremor group muscle contraction pattern was predominantly synchronous, as do all enhanced physiological, and physiological tremor patients, but with more fine low amplitude muscle bursts. By varying the tremor frequency and the weight load effect, tremor analysis could discriminate essential from enhanced physiological, and physiological tremors.\u0000Conclusions: The tremor analysis using surface electromyography and an accelerometer is sufficient to differentiate between essential tremors, enhanced physiological tremors, and physiological tremors.\u0000 ","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48935721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expanded disability status scale in Multiple Sclerosis: Relationship to visual evoked potential 多发性硬化症的扩展残疾状态量表:与视觉诱发电位的关系
mjl@ kly@ lTb Pub Date : 2022-07-24 DOI: 10.32007/jfacmedbagdad.6421925
Rand Salih, Hanan L. Al-Omary
{"title":"Expanded disability status scale in Multiple Sclerosis: Relationship to visual evoked potential","authors":"Rand Salih, Hanan L. Al-Omary","doi":"10.32007/jfacmedbagdad.6421925","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6421925","url":null,"abstract":"Background: Multiple sclerosis (MS) prevalence in Iraq is 11.73/100,000 it causes disability in younger adults. Expanded Disability Status Scale (EDSS) can monitor MS disability while Visually Evoked Potentials (VEP) serves as a marker of myelination.\u0000Objectives: To explore the relationship between EDSS and VEPs in multiple sclerosis patients.\u0000Patients and Methods: A cross-sectional study was conducted in Ghazi Al- Hariri Hospital from first of Nov 2021 till the end of Jan 2022. Fifty patients with multiple sclerosis were compared to 50 healthy individuals. EDSS Data were collected using a structured questionnaire, P100 latency were measured using VEP. The Correlation was used to investigate the relationship between P100- latencies and EDSS. P value ≤0.05 was considered significant.\u0000Results: The average age of MS cases was 33.5±8.01 years, and the mean EDSS was 2.8±2.86. A significant difference in the latency period was reported. The study showed a significant positive correlation between EDSS and P100 latency period.\u0000Conclusions: Using non-invasive procedures like VEPs can help to monitor and detect deterioration and improvement in MS patients.","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45474597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Traumatic Haemothorax: Diagnostic approaches and surgical management 外伤性血栓:诊断方法和手术治疗
mjl@ kly@ lTb Pub Date : 2022-07-24 DOI: 10.32007/jfacmedbagdad.6421889
W. Hussen, Ahmed Noureldin Abdulkadir, Akeel S. Yuser
{"title":"Traumatic Haemothorax: Diagnostic approaches and surgical management","authors":"W. Hussen, Ahmed Noureldin Abdulkadir, Akeel S. Yuser","doi":"10.32007/jfacmedbagdad.6421889","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6421889","url":null,"abstract":"Background: Traumatic haemothorax is a collection of blood within the pleural cavity due to a penetrating or blunt injury leading to blood accumulation inside the pleural space with its respiratory and hemodynamic consequences.\u0000Objectives: Is to retrospectively study eighty victims of traumatic haemothorax regarding their age, gender, types of injury, and their sequel, as well as the methods of investigation, treatment modality (conservative or operative) and their outcome.  \u0000Patients and methods: The data of 80 patients with traumatic haemothorax admitted to Ibn AL-Nnafees teaching hospital from (1st of August 2018 to 30th. of September 2019), was collected. The data was analyzed according to age, gender, clinical features, associated findings, mechanism of injury, imaging, procedure performed, operative finding, post-operative outcome, morbidity, mortality and follow up.\u0000Result: Seventy-four (92.5%) of our patients were males, and 32 (40%) were between 21-30 year of age. Fifty-four patients (67.5%) were injured by bullet, stab or shell injury. The remaining 26 patients (32.5%) were affected by blunt injury. Sixty patients (75%) were treated successfully with tube thoracostomy only. Eight patients (10%) required emergency thoracotomy after the insertion of chest tube, ten patients (12.5%) needed elective thoracotomy for (clotted haemothorax, foreign body extraction or empyema), and the remaining two patients (2.5%) presented with minimal haemothorax and didn’t need any intervention. Sixty-two of our patients (77.5%) were discharged well within 7 days. Those with air leak or who needed thoracotomy (elective or emergency) had longer hospitalization periods. Only one patient with empyema needed to stay more than 30 days. Sixty-nine (86.3%) of our patients were discharged well, while complication occurred in three patients (3.8%) with air leak, two (2.5%) ended with empyema and four patients (5%) with clotted haemothorax. Two patients (2.5%) died due to sever uncontrolled bleeding.\u0000Conclusion: Most of the patients with traumatic haemothorax were simply managed by tube thoracostomy only. In haemodynamically unstable patients, no time should be wasted for investigations and a resuscitative thoracotomy can save the patient’s life. Rapid assessment and early intervention will save the life of patient with traumatic haemothorax.","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45550039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between serum fructose level and insulin resistance in women with polycystic ovary syndrome: The effect of obesity 多囊卵巢综合征患者血清果糖水平与胰岛素抵抗的关系:肥胖的影响
mjl@ kly@ lTb Pub Date : 2022-07-24 DOI: 10.32007/jfacmedbagdad.6421926
Ameera Hatem, Basil O Saleh, Afraa M Al-Naddawi
{"title":"Association between serum fructose level and insulin resistance in women with polycystic ovary syndrome: The effect of obesity","authors":"Ameera Hatem, Basil O Saleh, Afraa M Al-Naddawi","doi":"10.32007/jfacmedbagdad.6421926","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6421926","url":null,"abstract":"Background: Polycystic ovary syndrome (PCOS) women's most prevalent endocrinology condition is a mixture of environmentally and genetically adduced causing PCOS. The relationship between monosaccharide and PCOS is largely unknown.\u0000Objective: This research was designed to investigate the relationship between blood levels of fructose, insulin resistance, and androgen hormone in women with PCOS, and the effect of obesity on the obtained result, as well as to study the efficacy of serum fructose as a biomarker in the diagnosis of PCOS.\u0000Cases and methods: This case-control research study was conducted at the Gynecology Clinic and Infertility Center, in Baghdad Teaching Hospital / Medical City between November 2021 to March 2022. It involved 120 women between the ages of 18-40 year. Fifty-nine women (cases) were newly diagnosed with PCOS by a gynecologist and 61 age and BMI matched healthy women (controls). PCOS women were subdivided according to their body mass index into four groups: lean, normal weight, overweight and obese. Investigations included serum measurements of fructose, luteinizing hormone (LH), follicular stimulating hormone (FSH), free testosterone, insulin, glucose, and calculated homeostasis model assessment- insulin resistance (HOMA-IR) and quantitative insulin sensitivity check index (QUICKI).\u0000Results: The mean ±SD values of serum fructose, glucose, insulin and HOMA-IR were significantly augmented in PCOS women as compared to controls (p< 0.001), while mean value of QUICKI was significantly decreased (p<0.0001). There was a significant positive correlation between BMI values and fructose levels in PCOS women. The result showed that serum fructose and free testosterone levels had the highest sensitivity and specificity in the differentiation between the PCOS group and the controls, with the area under curve values for free testosterone higher than area under curve values for fructose.\u0000Conclusions: The fructose level can be used as an alternative biomarker for women with PCOS independent of insulin resistance. The majority of PCOS women are obese and overweight, and a minority are lean who are severely complicated by insulin resistance.\u0000 ","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48655737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Isolation and Identification of H. pylori among Iraq patients with chronic gastric inflammation 伊拉克慢性胃炎患者幽门螺旋杆菌的分离鉴定
mjl@ kly@ lTb Pub Date : 2022-07-24 DOI: 10.32007/jfacmedbagdad.6421929
Fatima omer Saber, M. Ali
{"title":"Isolation and Identification of H. pylori among Iraq patients with chronic gastric inflammation","authors":"Fatima omer Saber, M. Ali","doi":"10.32007/jfacmedbagdad.6421929","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6421929","url":null,"abstract":"Background: H. pylori is one of the gastrointestinal organisms in which more than half the world's population was infected. The aim of this study was to Isolation, identity, and determine antibiotic susceptibility of H. pylori from samples of the patient (biopsies) using various procedures.\u0000Patients and methods: A total of 90(58 males, 32females) patients with different age groups from both genders are involved in this study suffering from dyspeptic symptoms They underwent diagnostic ‘upper’ gastrointestinal (G.I.) endoscopy at “Endoscopy unit of AL- Sadder Teaching Hospital in Baghdad “during the period November 2021 to March 2022.\u0000Results: The results showed a relationship between H. pylori infection occurrence and endoscopic ally diagnosed dyspeptic patients; it was recorded that H. pylori was isolated in 30 cases. Antibiotic resistance test for H. pylori isolates showing susceptibility to levofloxacin, clarithromycin, ciprofloxacin, and amoxicillin. Whereas all the tested isolates were appearing resistant to metronidazole, and tetracycline.\u0000Conclusion: The results showed a relationship between H. pylori infection occurrence and endoscopic ally diagnosed dyspeptic patients. Culture and antibiotic sensitivity assay for detection of H. pylori are more reliable in biopsies than urease tests. H. pylori isolates were sensitive to levofloxacin, clarithromycin, ciprofloxacin, and amoxicillin.\u0000 ","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48781683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书