多发性硬化症的扩展残疾状态量表:与视觉诱发电位的关系

Rand Salih, Hanan L. Al-Omary
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引用次数: 0

摘要

背景:多发性硬化症(MS)在伊拉克的患病率为11.73/100000,它会导致年轻人残疾。扩展残疾状态量表(EDSS)可以监测MS残疾,而视觉诱发电位(VEP)可以作为髓鞘形成的标志。目的:探讨多发性硬化患者EDSS与VEPs的关系。患者和方法:从2021年11月1日至2022年1月底,在Ghazi Al-Hariri医院进行了一项横断面研究。将50名多发性硬化症患者与50名健康人进行比较。EDSS数据采用结构化问卷收集,P100潜伏期采用VEP测量。相关性研究P100潜伏期与EDSS的关系。P值≤0.05被认为是显著的。结果:MS患者的平均年龄为33.5±8.01岁,EDSS平均值为2.8±2.86。据报道,潜伏期存在显著差异。研究表明EDSS与P100潜伏期呈显著正相关。结论:使用VEP等非侵入性程序有助于监测和检测MS患者的病情恶化和改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Expanded disability status scale in Multiple Sclerosis: Relationship to visual evoked potential
Background: Multiple sclerosis (MS) prevalence in Iraq is 11.73/100,000 it causes disability in younger adults. Expanded Disability Status Scale (EDSS) can monitor MS disability while Visually Evoked Potentials (VEP) serves as a marker of myelination. Objectives: To explore the relationship between EDSS and VEPs in multiple sclerosis patients. Patients and Methods: A cross-sectional study was conducted in Ghazi Al- Hariri Hospital from first of Nov 2021 till the end of Jan 2022. Fifty patients with multiple sclerosis were compared to 50 healthy individuals. EDSS Data were collected using a structured questionnaire, P100 latency were measured using VEP. The Correlation was used to investigate the relationship between P100- latencies and EDSS. P value ≤0.05 was considered significant. Results: The average age of MS cases was 33.5±8.01 years, and the mean EDSS was 2.8±2.86. A significant difference in the latency period was reported. The study showed a significant positive correlation between EDSS and P100 latency period. Conclusions: Using non-invasive procedures like VEPs can help to monitor and detect deterioration and improvement in MS patients.
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