mjl@ kly@ lTbPub Date : 2023-04-27DOI: 10.32007/jfacmedbagdad.6512058
Ahmed M. Kmkm, Mowafaq M. Ghareeb
{"title":"Natural Oil Nanoemulsion-Based Gel Vehicle for Enhancing Antifungal Effect of Topical Luliconazole","authors":"Ahmed M. Kmkm, Mowafaq M. Ghareeb","doi":"10.32007/jfacmedbagdad.6512058","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6512058","url":null,"abstract":"Background: Luliconazole, a newer class of imidazole anti-fungal agent, is very effective against several species of fungi, especially dermatophytes. It has very low aqueous solubility acting as barrier for topical delivery and limiting its dermal availability.\u0000Aim of the study: This study aimed to formulate luliconazole oil/water nanoemulsion by the aqueous titration method.\u0000Methods: Solubility study resulted in selecting peppermint oil, tween 80 and transcutol p as oil phase, surfactant and cosurfactant respectively, although pseudoternary phase diagram construct nanoemulsion area for picking formulations. Fifteen o/w nanoemulsion formulations prepared and characterised for droplet size, polydispersity index, pH values, percent transmittance, luliconazole content. Among formulations, eight preparations introduced to enhance the viscosity of prepared nanoemulsion by combining 0.5% carbopol 934 as gelling agent.\u0000Results: The selected preparations demonstrated homogeneous nanoemulgels with pH values appropriate for skin application and accepted luliconazole content. Viscosity results manifested non-newtonian pseudo plastic behavior with shear-thinning viscosity profile. In vitro release studies revealed dissimilar release profile (f2˂50) than that of pure luliconazole dispersion. The results revealed that the formula NG-1 with oil: Smix(2:1):water (15:40:43.5) ratio containing 1% drug and 0.5% carbopol 934 was the optimised formula with excellent spreadability.\u0000Conclusion: The study concluded that nanoemulsion-based gel is contemplated an encouraging and proceed technique for the topical preparation and upgrade solubility, dissolution rate and permeability of insufficient water-soluble drugs across the skin.","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46831444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
mjl@ kly@ lTbPub Date : 2023-04-27DOI: 10.32007/jfacmedbagdad.6512064
Salaah Aldeen M. Sadeq Alkubaisi, IbrahimAbdul-H. Al-Zubaidy
{"title":"Toxoplasmosis in females from Al-Anbar, Iraq","authors":"Salaah Aldeen M. Sadeq Alkubaisi, IbrahimAbdul-H. Al-Zubaidy","doi":"10.32007/jfacmedbagdad.6512064","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6512064","url":null,"abstract":"Background: Toxoplasmosis is a common zoonotic disease affecting one-third of the world population with potentially serious health implications.\u0000Aim of the study: To find the prevalence and risk factors of Toxoplasma gondii infection among females in Al-Anbar, Iraq. \u0000Methodology: Over an eight-month period from (1st November 2021 to 30th June 2022), 200 females visiting private veterinary clinics in Al-Anbar (92 owned cats) participated in this prospective study. Age and residency were recorded. Blood samples were collected from all females and subjected first to the Toxoplasma Latex Agglutination test (TLAT). Samples of cat feces were collected from 57 (62%) pet and 35 (38%) stray cats and subjected first to direct microscopy looking for Toxoplasma oocysts. Blood and fecal samples were then tested by nested polymerase chain reaction (n-PCR) and real-time PCR. Results were then statistically analyzed.\u0000Results: Rates of human toxoplasmosis were (n=48, 24%), (n=60, 30%), and (n=77, 38.5%) with TLAT, n-PCR, and RT-PCR tests respectively. Likewise, rates of cat toxoplasmosis were (n=7, 7.6%), (n=55, 60%), and (n=80, 87.0%) with TLAT, n-PCR, and RT-PCR tests respectively. Results of the latex test revealed that females >40 had a high rate of infection (45.8%) compared with those aged 31-40 years (33.8%) and those aged 21-30 years (13.0%) (P≤0.01). City resident females had a lower infection rate compared to village residents (29.7% vs. 55.4%).\u0000Conclusions: Toxoplasmosis was more prevalent in females >40 from rural areas but wasn’t related to contact with cats. Real-time PCR provided a better diagnostic yield. ","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42486565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
mjl@ kly@ lTbPub Date : 2023-04-27DOI: 10.32007/jfacmedbagdad.6512008
Alaa Ghaith Ahmed, Mohammed Qasim Yahya MalAllah Al Atrakji, Wifaq M.Ali Alwattar
{"title":"Antibacterial effect of ethyl acetate fraction of Medicago Sativa on Escherichia Coli in urinary tract infections","authors":"Alaa Ghaith Ahmed, Mohammed Qasim Yahya MalAllah Al Atrakji, Wifaq M.Ali Alwattar","doi":"10.32007/jfacmedbagdad.6512008","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6512008","url":null,"abstract":"Background: One of the most dominant bacterial infections is urinary tract infection (UTI), both in the community and in the hospital settings Since drug resistance become one of the predominant problems of health worldwide, it is necessary to use new methods to overcome drug-resistant bacteria. In this regard, medicinal plants (Medicago sativa ) are considered one of the richest sources to produce antibiotics. \u0000Aim of the study: evaluate the antibacterial effect of the fraction of ethyl acetate of Medicago Sativa extract against Escherichia Coli isolated from urine samples of patients with urinary tract infections. \u0000Material and methods: throughout this study 85 urine samples were taken from patients attending one of the hospitals in Iraq's Medical City complex, the study was conducted between December 2021 and May 2022, Semi-quantitative culture techniques were used to culture the urine samples, and conventional microbiological methods were used to identify the bacteria. the Kirby-Bauer Disk diffusion method was used for testing antibiotic susceptibility. The antibacterial effect of Medicago Sativa was tested by preparing Medicago sativa crude extract in 85 percent ethanol in the soxhlet apparatus. The extract is then fractionated into ethyl acetate fraction, then the effectiveness against uropathogenic E. coli was tested at various concentrations (25 mg/ml, 50 mg/ml, and 75 mg/ml). \u0000Result: 60% of the population was female compared to 40% of the male in UTI patients with E.coli. Concerning age, the majority of study participants (20–39 years) were under 40 years old (56.7%), and all isolates show complete meropenem sensitivity. The extracts from Medicago Sativa showed significant antibacterial activity against E.Coli. \u0000Conclusion: Medicago sativa extracts have excellent potential as an antibacterial agent against uropathogenic E. coli, according to the current investigation findings. \u0000Keywords: Escherichia coli, Ethyl acetate fraction, Medicago sativa extract, UTIs","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41695707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
mjl@ kly@ lTbPub Date : 2023-04-27DOI: 10.32007/jfacmedbagdad.6512040
Maad M. Shallal, Najmah Mahmood, Zina A. Hussein
{"title":"Total L-carnitine and insulin resistance in non-obese and obese Iraqi women with polycystic ovary syndrome","authors":"Maad M. Shallal, Najmah Mahmood, Zina A. Hussein","doi":"10.32007/jfacmedbagdad.6512040","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6512040","url":null,"abstract":"Background: Polycystic ovary syndrome (PCOS) is one of the most frequent endocrine illnesses affecting reproductive - age women. L-carnitine has important roles in oxidative stress, energy production and glucose metabolism. It affects insulin resistance as decreased plasma carnitine level has been well reported in type II diabetes mellitus. Hence, it means L-carnitine may reduce insulin resistance which is found in PCO disease.\u0000Objective: This study aims to measure the level of L-carnitine and insulin resistance in both obese and non- obese patients with PCOS.\u0000Patients and Methods: Sixty women within the reproductive age with PCOS (30 obese and 30 non- obese) were recruited from the Gynecology and Obstetrics Outpatient Clinic in Baghdad Teaching Hospital from June 2016 to June 2017. The data collected for each case included: Height, weight, waist circumference, blood pressure, obstetrical, medical, and medication history as well as ultrasound results. A physical examination was done to evaluate the clinical signs of hyperandrogenism. Biochemical measurements included fasting blood sugar, leutinizing hormone, follicular stimulating hormone, Testosterone and lipid profile were measured together with total L-carnitine (using L-Carnitine Assay Kit Sigma-Aldrich Co.). Insulin resistance was diagnosed according to National Cholesterol Education Program/Adult Treatment Panel III (NCEP/ATP III). PCOS is diagnosed according to the Rotterdam criteria.\u0000Results: This study revealed that insulin resistance (IR) was present in 51.7% of PCOS patients, which was higher in obese PCOS patients (73.3%) than in the non-obese (30%). Age of patients, serum cholesterol, LH, and FSH were not related to IR. High mean BMI, waist circumference, FBS and triglyceride were significantly associated with IR (p < 0.05), while low serum HDL and L-Carnitine were associated with IR (p < 0.05). The mean serum total L-carnitine in this study was 34.03μmol/L. Obese women had lower carnitine levels than non-obese women and low serum L-Carnitine was associated with IR. Serum triglyceride, FBS and testosterone were correlated negatively with serum L-carnitine (p < 0.05) and serum HDL correlated positively with serum L-carnitine (p value = 0.001).\u0000Conclusions: The mean value of serum total L-carnitine among the non-obese PCOS women was higher than among the obese ones. Low serum L-carnitine is associated with insulin resistance","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47964745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
mjl@ kly@ lTbPub Date : 2023-04-27DOI: 10.32007/jfacmedbagdad.6511980
N. S. Dawood, Numan S. Dawood, Maan H. Al-khalisy
{"title":"Evaluation of the effect of type II diabetes mellitus on Bone Mineral Density of Upper and Lower Limbs by Dual-Energy X-Ray Absorptiometry","authors":"N. S. Dawood, Numan S. Dawood, Maan H. Al-khalisy","doi":"10.32007/jfacmedbagdad.6511980","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6511980","url":null,"abstract":"Background: Bone mineral density has been assessed using Dual-Energy X-Ray Absorptiometry. Bone mineral density is measured according to the results of the Dual-Energy X-Ray Absorptiometry examination of the vertebral column and pelvis. Although diabetes mellitus type II (DM) is known to affect bone mineral density, at the present time this particular relationship is not clear.\u0000 Objective: The aim of current study was to evaluate the effects of type II diabetes mellitus on bone mineral density of the upper and lower limbs as well as gender differences. \u0000Patients and Methods: This study involved 165 patients complaining of bone pain (85 males and 80 females), 85 patients of who suffered from diabetes, involving both genders. In addition, 90 apparently healthy volunteers had been studied and were considered to constitute the control group. All individuals (255) were studied regarding their bone mineral density via Dual-Energy X-Ray Absorptiometry for all parts of the body.\u0000Results: The Dual-Energy X-Ray Absorptiometry exam revealed highly statistically significant differences between the sides of the body in the same person. In addition, there were significant differences in bone mineral density between females and males, as well as between the control and patient groups with type II diabetes mellitus.\u0000 Conclusion: Our results indicated that the bone mineral density of women was less than that in men in all cases (normal, osteoporosis, and diabetes mellitus type II (DM) with osteoporosis). Other results obtained from this research revealed that diabetes mellitus type II (DM) can be considered to be one of the major causes of osteoporosis in the general population","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":"1217 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41279047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
mjl@ kly@ lTbPub Date : 2023-04-27DOI: 10.32007/jfacmedbagdad.6512036
Mirna Faiq, Eman S. Saleh, Omar B. Fathalla
{"title":"High Serum High Mobility Group A1 (HMGA1) Levels are associated with presence of Metabolic Syndrome: Case-control study","authors":"Mirna Faiq, Eman S. Saleh, Omar B. Fathalla","doi":"10.32007/jfacmedbagdad.6512036","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6512036","url":null,"abstract":"Background: Metabolic syndrome is a complex series of metabolic defects, characterized by high levels of serum glucose, hypertension, abdominal obesity, and dyslipidemia. The high mobility group AT-hook1, an architectural transcript factor, affects the homeostasis of glucose. No previous studies have been performed to examine whether HMGA1 can be secreted into the extracellular milieu.\u0000Objectives: this case-control study aimed to examine whether HMGA1 secretes into the extracellular milieu and compares its serum level in two groups of metabolic syndrome (with and without diabetes) and a control group composed of apparently healthy individuals of Iraqi population with different nationalities.\u0000Patients and Methods: Sixty-one patients with metabolic syndrome and thirty healthy Iraqi participants included in this study. Serum HMGA1 concentrations were determined by enzyme linked immuno sorbent assay (ELISA). Lipid profile, serum (glucose and insulin), HbA1c, systolic/diastolic blood pressure, body mass index, and waist circumference were also measured. The statistical analysis was done using IBM SPSS software for Windows version 26.0.\u0000Results: Significant difference in HMGA1 level was seen (P = 0.000), between metabolic syndrome with diabetes, metabolic syndrome without diabetes and control group. Higher concentrations were seen in metabolic syndrome patients with diabetes followed by metabolic syndrome patients without diabetes and then the control group, and no significant difference was seen in the serum level based on nationality. Significant positive correlation was found between HMGA1 and fasting blood glucose (p=0.001) as well as between HMGA1 and HbA1c (p= 0.015) in patients with metabolic syndrome. Moreover there was a significant association between HMGA1 levels and the risk of metabolic syndrome. The risk of metabolic syndrome was found to be increased by a high HMGA1 level, odds ratio (OR), 0.411 (95% CI, 0.208-0.813).\u0000Conclusions: This case-control study found that circulating HMGA1 concentration was significantly higher in Mets mainly in those with T2DM. Also, the high concentration of HMGA1 was found to present a significant risk of metabolic syndrome regardless of whether diabetes is present or not. Besides HMGA1 serum level was positively correlated with parameters of diabetes including HbA1c and FBG.\u0000 ","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43073556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
mjl@ kly@ lTbPub Date : 2023-04-27DOI: 10.32007/jfacmedbagdad.6511951
Zina S. Abdulrahman Aldaggistany, Ihab S. Ahmed, Zuhair Al-Johar
{"title":"Prevalence and Demographic characteristics of Metabolic Syndrome in Iraqi Patients with Acute Coronary Syndrome","authors":"Zina S. Abdulrahman Aldaggistany, Ihab S. Ahmed, Zuhair Al-Johar","doi":"10.32007/jfacmedbagdad.6511951","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6511951","url":null,"abstract":"Background: The demographic characteristics of Iraqi patients with the metabolic syndrome (MS) and presenting with acute coronary syndrome (ACS) has been scarcely studied before.\u0000Aim of the study To study the socio-demographic characteristics of a group of Iraqi patients with MS presenting with ACS.\u0000Patients and Methods: A convenience sample of 150 cases presenting with ACS and admitted to the coronary care unit (CCU) of Al-Yarmouk Teaching Hospital in Baghdad from mid-January through July 2011 were included in the current cross-sectional study. The data needed for the study was collected through a direct interview to fill a questionnaire by all cases carried out by a consultant physician.","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43087258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
mjl@ kly@ lTbPub Date : 2023-04-27DOI: 10.32007/jfacmedbagdad.6511910
Maryam AL-Ani, Qusay A. Fahed, Ali I. Shyaa
{"title":"Clinical importance of imaging anatomical signs in predicting transverse sinus dominance using conventional magnetic resonance imaging","authors":"Maryam AL-Ani, Qusay A. Fahed, Ali I. Shyaa","doi":"10.32007/jfacmedbagdad.6511910","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6511910","url":null,"abstract":"Background: Differentiating flow gaps associated with hypoplastic transverse sinus from venous thrombosis is a diagnostic challenge in brain magnetic resonance imaging with venography.\u0000Objectives: To assess the clinical benefit of anatomical signs to anticipate the side of the dominant transverse sinus.\u0000Patients and Methods: A total of 100 patients underwent brain magnetic resonance imaging with venography at the radiology department /medical city and were retrospectively reviewed for the direction of superior sagittal sinus flow void, inclination of sulcus for the superior sagittal sinus, angulation of the posterior falx and direction of occipital lobe bending in axial non-contrast T1 weighted image, then compare these findings with a side of the dominant transverse sinus in magnetic resonance venography.\u0000Results: Inclination of sulcus for superior sagittal sinus and superior sagittal sinus flow void direction toward the right side had high positive predictive values (95.5%) and (93.2 %) in proper matching with the right transverse sinus dominance, respectively. Right-sided angulation of the posterior flax and rightward direction of the occipital lobe had a positive predictive value of (90.9 %) in predicting transverse sinus dominance.\u0000Conclusion: The side of dominant transverse sinus can be anticipated by reviewing anatomical signs in T1 weighted image, which may help to differentiate hypoplastic transverse sinus from venous thrombosis that aid in better interpretation of brain MRI- MRV examinations.\u0000 ","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46847385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
mjl@ kly@ lTbPub Date : 2023-04-27DOI: 10.32007/jfacmedbagdad.6512014
N. Hameed, Shealan Khudhair Abbas Abbas
{"title":"The Use of Off-label and Unlicensed Drugs for Neonates: A Report from a Teaching Hospital in Baghdad","authors":"N. Hameed, Shealan Khudhair Abbas Abbas","doi":"10.32007/jfacmedbagdad.6512014","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6512014","url":null,"abstract":"Background: Neonates who are admitted to hospitals will need various drugs. The use of unlicensed or off-label drugs without scientific evidence makes this exposure unsafe.\u0000Aim of study: We aimed to assess the use of drugs for neonates based on the British National Formulary for Children and IBM Micromedex Neofax.\u0000Patients and methods: This is a descriptive study which reviewed the clinical files of enrolled neonates who have stayed in the hospital for more than 24 hours and received at least one drug. It was conducted in the neonatal care unit of the Children Welfare Teaching Hospital/ Medical City Complex in Baghdad during the period from 1st of January to 30th of June/2018. The data was entered on a predesigned format and analyzed by using the appropriate statistical methods.\u0000Results: A total number of 1079 neonates were admitted to the NCU during the study period, of whom 967 were included in the current study with 597 (61.7%) males and 370 (38.3%) females. There were 424 (43.8%) preterm, 496 (51.3%) term and post term neonates, and 47 (4.9%) neonates with unknown gestational age. Different classes of drugs were used with a total of 56 drugs, of which 33.9% were unlicensed and 66.1% were off-label. Accordingly, 42.5% of the neonates received unlicensed drugs and almost all patients received at least one off-label drug. Major risk factors for such use include mechanical ventilation, male sex and prolonged hospitalization.\u0000Conclusions: In hospitalized neonates, drugs were more frequently prescribed as an off-label rather than unlicensed. Almost all neonates were exposed to off-label formulations.","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44359686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
mjl@ kly@ lTbPub Date : 2023-04-27DOI: 10.32007/jfacmedbagdad.6512041
Maryam K. Ali, S. Jawad, Yasmeen J. Al-Bayaa
{"title":"Review article of Streptococcus pyogenes infection: Rick factors, prevention and management strategies","authors":"Maryam K. Ali, S. Jawad, Yasmeen J. Al-Bayaa","doi":"10.32007/jfacmedbagdad.6512041","DOIUrl":"https://doi.org/10.32007/jfacmedbagdad.6512041","url":null,"abstract":"Background:-Streptococcus pyogenes is an exclusively human pathogen. This bacterial species is responsible for a large variety of infections.\u0000Objective: This review identified published articles on the risk factors, prevention and control strategies for streptococcus diseases.\u0000Material and methods: A systematic search was carried out to identify papers published on the Web of Science, PubMed, Scopus, and Google Scholar electronic databases in an attempt to provide basic information about Streptococcus infections, potential risks for their spread, and treatment and prevention strategies.\u0000Results: The more common methods for Streptococcus pyogenes transmission are through respiratory droplets, skin lesions brought on by Streptococcus pyogenes contact with infected objects or devices. Another potential mode is foodborne transmission but more research is needed to determine this infection route. Native communities, and those of low socio-economic status worldwide were found particularly susceptible to Streptococcus diseases, as well as children, older adults and those with impaired immune system. Those groups are susceptible to Streptococcus pyogenes infections and their complications with higher infectious rates in educational institutions, hospitals, over-crowding and the continuous increase in social contact. The importance of improving living conditions and personal and hand hygiene is one of the techniques in the management and prevention of Streptococcus pyogenes infections. Infection control methods must be highlighted with greater precision.\u0000Conclusion: Prevention and control measures should target the improvement of living conditions, and personal and hand hygiene. Adherence to infection prevention and control practices should be emphasized in high-risk settings.","PeriodicalId":33125,"journal":{"name":"mjl@ kly@ lTb","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43163712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}