{"title":"Commentary: The Impetus to Explore Alternative Courses of Treatment for Overactive Bladder","authors":"Or Yaacov","doi":"10.53043/2832-7551.jcmcr.2.006","DOIUrl":"https://doi.org/10.53043/2832-7551.jcmcr.2.006","url":null,"abstract":"Citation: Orlin Yaacov. Commentary: The Impetus to Explore Alternative Courses of Treatment for Overactive Bladder. J Clin Med Current Res. (2022);2(2): 1-2 1. Background Twenty-five million Americans and 200 million people worldwide suffer from incontinence and overactive bladder syndrome (OAB), costing the US economy upward of $80 billion annually [1]. According to the CDC, the average patient suffers for over six years before consulting their doctor about their bladder issues, 64% of patients that discuss their symptoms with a physician reach the conclusion that OAB is an illness that they are just going to have to live with [2]. 92% of all OAB patients have discontinued treatment due to lack of efficacy or adverse effects within two years [2]. Recently approved drug classes, including beta-3 adrenergic agonists and advances in neuromodulation along with the acceptance of telemedicine and big-data-driven care, lead this author to believe that it is time to rethink the paradigm of OAB care.","PeriodicalId":330764,"journal":{"name":"Journal of Clinical Medicine: Current Research","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114352098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Development Innovation in Rare Diseases: Overcoming Barriers to Successful Delivery of A Randomised Clinical Trial in Alkaptonuria","authors":"Ranganath Lr, Sireau N","doi":"10.53043/ndcr-2-008","DOIUrl":"https://doi.org/10.53043/ndcr-2-008","url":null,"abstract":"Alkaptonuria (AKU) (OMIM#203500) is a rare inherited disorder due to deficiency of homogentisate dioxygenase with resultant accumulation of homogentisic acid, occurring with a worldwide frequency of 1 in 100,000 to 250,000 [1].","PeriodicalId":330764,"journal":{"name":"Journal of Clinical Medicine: Current Research","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126097316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Why Mothers Avoid Breastfeeding?","authors":"J. Mao","doi":"10.53043/ndcr-2-007","DOIUrl":"https://doi.org/10.53043/ndcr-2-007","url":null,"abstract":"Citation: Jing Mao. Why Mothers Avoid Breastfeeding?. J Clin Med Current Res. (2022);2(2): 1-2 It is widely known that breastfeeding has many beneficial, both short and long-term health effects for mother and infant [1] and has been recognized as the optimal mode of feeding internationally. Nevertheless, certain women decide to not initiate breastfeeding after giving a childbirth, what may have a serious implication on not only their health, but most importantly, health of their infants. In the past twenty years, only a few studies have attempted to explore the reasons for non-initiation, despite of these possible consequences.","PeriodicalId":330764,"journal":{"name":"Journal of Clinical Medicine: Current Research","volume":"140 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115084992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Georgios I. Karaolanis MD, D. Nikas, Z. Williams, E. Georgakarakos, Demetrios Moris
{"title":"Management of Asymptomatic Carotid Stenosis. an Issue with Unresolved Queries that Need Disambiguation","authors":"Georgios I. Karaolanis MD, D. Nikas, Z. Williams, E. Georgakarakos, Demetrios Moris","doi":"10.53043/2832-7551.jcmcr.2.009","DOIUrl":"https://doi.org/10.53043/2832-7551.jcmcr.2.009","url":null,"abstract":"","PeriodicalId":330764,"journal":{"name":"Journal of Clinical Medicine: Current Research","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132953815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}