mjl@ lmstnSry@ lTby@最新文献

{"title":"Cosmetic and functional outcomes of single-stage feminizing genitoplasty in children with congenital adrenal hyperplasia","authors":"Moamin J. Salim, A. Al-Mayoof, A. Joda, O. Almushhadany","doi":"10.4103/mj.mj_32_21","DOIUrl":"https://doi.org/10.4103/mj.mj_32_21","url":null,"abstract":"Introduction: Evaluating the cosmetic and functional outcomes in girls with congenital adrenal hyperplasia (CAH) is essential to criticize the effectiveness of single-stage feminizing genitoplasty (SSFG). Objective: The aim of this study is to evaluate the outcomes of SSFG in terms of cosmetic and functional results for girls with CAH. Materials and Methods: A prospective study involves the performance of SSFG for patients with CAH in two pediatric surgery centers for a period of 9 years. The surgical procedure was either total or partial urogenital mobilization. The cosmetic and anatomical outcomes were evaluated according to Creighton criteria as good, satisfactory, and poor. The patients were followed up for 4–9 years. Results: The study included 55 girls with CAH, the mean age at operation was 4.1 ± 1.2 years. Most of cases are prader Stage II (42%). Total urogenital mobilization was performed in 74.5% of patients. Vaginal stenosis was the most common complication (11%). Urinary incontenance registered in 3 cases. The cosmetic and functional outcome was good in (65.5%), satisfactory (21.8%), and poor in (12.7%). Conclusion: Early SSFG is effective in providing good cosmetic and functional outcome in patients with CAH.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48629405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interferon-gamma: Has acromegaly and diabetes an impact on such marker?","authors":"S. Hamza, Zainab F. Ashoor, A. Rahmah","doi":"10.4103/mj.mj_26_21","DOIUrl":"https://doi.org/10.4103/mj.mj_26_21","url":null,"abstract":"Background: Acromegaly is a rare endocrine disease, its incidence is 4-6 per million per years while its prevalence is 40-60 per million. The distinctive facial characteristics are prognathism prominent forehead, and large hands and feet. This happens after the fusion of growth plates; separating acromegaly from gigantism that occurs before growth plates are closed. Interferon-gamma was checked in (80) acromegalic patients (50% are diabetics and 50% are non-diabetics) while (40) persons were regareded as healthy control group being non-diabetic, non-acromegalic. Aim of the study: To find out impact lnterferon-gamma in diabetic acromegalic versus non-diabetic acromegalic patients.Methods: Eighty acromegalic subjects were enrolled in across sectional study by measuring the level of lnterferon-gamma in the sera of diabetics and non-diabetics as 39 are diabetics while the remaining 41 patients are non-diabetic. Result: lnterferon-gammais high among diabetic acromegalic patients when compared with non-diabetic acromegalic subjects. Conclusion: Interferon gamma is high in acromegalic diabetic patients, nondiabetic acromegalic patients, and controls (100%, 97.6%, and 97.5%, respectively). Interferon gamma is elevated in patients with acromegaly only in the age group of 30–39 years, but in those with diabetes, the elevation is noticed later within the age group of 40–49 years as if concomitant diabetes delays its elevation.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47172242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronavirus disease-19 pandemic and telework: Banking upon the collaboration between workers and employers","authors":"S. Shrivastava, P. Shrivastava","doi":"10.4103/mj.mj_8_22","DOIUrl":"https://doi.org/10.4103/mj.mj_8_22","url":null,"abstract":"The emergence of coronavirus disease-2019 (COVID-19) pandemic has brought about a significant change in the dynamics of health and the work profile. Telework refers to the practice of working remotely with the help of different information and communication technology applications and thereby continuing the work. Although telework definitely minimized the probability to acquire the COVID-19 infection, gradually evidence emerged suggesting problems resulting because of defective design of the workplace and long duration of working hours. It is an undeniable fact that the ongoing pandemic frankly resulted in an overnight change in the work pattern of all employees. To conclude, considering the trends of the COVID-19 pandemic, telework is expected to be there, even in the postpandemic period. This calls for the need to enhance collaboration between workers and employees to enable a reduction in the incidence of physical and mental illnesses and promotion of safe and healthy behavior.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46596789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular detection of agglutinin-like sequence 1 gene in Candida albicans that is isolated from diabetic foot patients","authors":"Mohammad A. Tariq, Uroba Abbas","doi":"10.4103/mj.mj_37_21","DOIUrl":"https://doi.org/10.4103/mj.mj_37_21","url":null,"abstract":"Objectives: Candida albicans is a microbe living within the natural human flora and is found in the upper respiratory tract, mouth, intestines, and vagina. C. albicans is able to cause infections that range from superficial infections of the skin to life-threatening systemic infections. Aim of Study: Detection of virulence gene agglutinin-like sequence (ALS) 1 by using molecular technology from clinical samples (C. albicans) that is isolated from ulcers of diabetic foot patients. Materials and Methods: This work was done on 235 patients who had diabetic foot patients admitted to the Specialized Center for Endocrinology and Diabetes (Baghdad Health Department/Rusafa) for the treatment of diabetic foot ulcers during November 2020 till March 2021. The collected samples of diabetic foot ulcers were cultured on different media (Sabouraud's dextrose agar with chloramphenicol for selective isolation and culturing of yeasts and HiCrome Candida Medium) for isolation of C. albicans fungus as well as automated biochemical test VITEK 2 system. The ALS1 virulence gene was detected by polymerase chain reaction using newly designed primers with a molecular size (419 bp). Results: Out of 235 Diabetic Foot Ulcer (DFU) cases, C. albicans were isolated in 20 (8.5%) patients (12 males and 8 females) of diabetic foot ulcers. In this study, the incidence of C. albicans infection at age [50–59 years] group was [40%], and increased at age group [60–69 years] to [55%], which represents the highest incidence of infection, then decreased in the age group [79–79 years] to [5%]). Seventy-five percent of the isolates were ALS1 gene positive. Conclusions: Diabetic people are more susceptible to infections due to their hyperglycemic environment and reduced immunity. The use of HiCrome Candida Identification Media with VITEK 2 system can help reduce the unnecessary steps of microorganism identification process. C. albicans infection is more common in males the females regarding diabetic foot ulceration. Majority of diabetic foot ulcers occur in older adults. ALS gene might be associated with diabetic foot ulceration.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42419041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of the pro-inflammatory cytokine interferon-gamma in type 2 diabetes and its correlation with atherosclerosis","authors":"Marwa Jasim Al-Tamimi, R. Al-Shawk, I. Al-Karawi","doi":"10.4103/mj.mj_13_21","DOIUrl":"https://doi.org/10.4103/mj.mj_13_21","url":null,"abstract":"Background: Immunity plays a major role in the development of atherosclerosis in type 2 diabetes mellitus (T2DM). Pro-inflammatory cytokines, such as interferon gamma (IFN-γ), play an important role in atherosclerosis-related inflammation. Aims: This study aims to determine whether IFN-γ level and AIP in patients with T2DM are associated with atherosclerosis development and the effect of IFN-γ concentration level in disease progression. Materials and Methods: This study involved 60 Iraqi T2DM patients (30 with dyslipidemia and 30 without dyslipidemia) with an age range of 35–70 years. For the purpose of comparison, 22 healthy participants comparable for T2DM were included in the study. Results: this study shows a significant increase in IFN-γ level in the patient groups as compared to the control group (P < 0.009). There was a gradualincrease of AIP in the three studied groups with a significant difference (P < 0.001). Conclusion: The level of IFN-γ and the AIPmay reflect the progression atherosclerosis which may give an alarming sign in studying group patients.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48736293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An unusual Cause of Persistent Frontal Headache in a 9-Year-Old Boy","authors":"S. Swain","doi":"10.4103/mj.mj_40_21","DOIUrl":"https://doi.org/10.4103/mj.mj_40_21","url":null,"abstract":"Headache is a common clinical experience of the patients and is found in all age groups. Intranasal mucosal contact with the absence of inflammation in the nasal cavity and paranasal sinuses may cause a secondary headache which is called a rhinogenic contact point headache (RCPH). RCPH is currently a topic of interest among clinicians and is accepted as a cause of headaches by the International Headache Society Classification. The diagnostic nasal endoscopy showed an S-shaped deviated nasal septum with intranasal mucosal contact in both nostrils. The headache of the child was disappeared after performing septoplasty and excision of the bilateral mucosal contact points. These anatomical variations in the nasal cavity in the pediatric age with bifrontal headache is a very rare clinical entity. Hence, clinicians and pediatricians should keep in mind RCPH during the evaluation of headaches in a pediatric patient. In this case report, a 9-year-old boy presented with a persistent bifrontal headache due to mucosal contact points in the nasal cavity.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45252333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of debriefing and feedback in facilitating learning through simulation-based medical education","authors":"S. Shrivastava, P. Shrivastava","doi":"10.4103/mj.mj_38_20","DOIUrl":"https://doi.org/10.4103/mj.mj_38_20","url":null,"abstract":"Clinical skills training has been acknowledged as one of the crucial domains of medical students' training and plays an important role in aiding them to become competent health-care personnel. The inclusion of simulation in medical curriculum has emerged as the approach to provide opportunities to undergraduate students to practice, learn, and assess skills in controlled settings and that too without harming the patients. Although mere participation in a simulation exercise might result in learning, the given feedback ascertains the attainment of the learning objectives. The conduction of the debriefing session after the simulation exercise is one of the most common ways to deliver feedback and it simultaneously gives the teacher an opportunity to understand the knowledge, skills, and attitude of the student, which contributed to the performance of the student in the simulation exercise. In conclusion, the components of feedback and debriefing are critical to ensure effective learning in simulation-based medical education. Thus, it is essential to plan for a feedback session and also train the teachers in the skills of administering feedback and debriefing and all the medical institutions implementing simulation-based education should strengthen the feedback element.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42620471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The value of combination of dynamic contrast-enhanced magnetic resonance imaging and diffusion-weighted imaging in the evaluation of breast masses","authors":"N. Mahmmud, Sara Ahmed, Ansam Othman","doi":"10.4103/mj.mj_8_21","DOIUrl":"https://doi.org/10.4103/mj.mj_8_21","url":null,"abstract":"Aim of the study: The aim was to characterize benign and malignant breast lesions on the basis of their magnetic resonance imaging (MRI) morphology and dynamic contrast enhancement in combination with the diffusion-weighted imaging (DWI) and their apparent diffusion coefficient (ADC) values at 1.5 T MRI, along with histopathological correlation. Patients and Methods: In this prospective study, 56 patients with suspicious breast mass who underwent 1.5 T MRI and proved by histopathology were included. Morphology was studied depending on the MRI signal intensity and dynamic contrast-enhanced imaging plus kinetic curve of enhancement of breast lesions. DWI and ADC values were calculated at b values of 0, 600, and 850 s/mm. The ADC value and histopathology correlation were analyzed. Results: Out of the 56 lesions, 27 lesions were histologically malignant (48.2%) and 29 were histologically benign (51.8%), with age range between 25 and 75 years, with a mean of 54.1 years, and with a standard deviation of ±12.69 years. The MRI results found a sensitivity (SN) of 85.2%, a specificity (SP) of 72.4%, a positive predictive value (PPV) of 74.2%, a negative predictive value (NPV) of 84%, and an accuracy of 78.6%. The DWI findings were as follows: 100% SN, 82.8% SP, 84.4% PPV, 100% NPV, and 85.3% accuracy. The combined MRI interpretation and DWI and ADC findings were as follows: 100% SN, 92.1% SP, 71.1% PPV, 100% NPV, and 86.4% accuracy. All malignant lesions showed restriction at DWI, while only 17.2% of the benign lesions are restricted at DWI. The mean of ADC value was higher in benign cases as compared to the malignant lesions (0.815 vs. 1.287 × 10−3) with statistically significant difference (P = 0.001). Conclusions: The combination of contrast-enhanced breast MRI with DWI and ADC value increases the diagnostic accuracy and SP in the characterization of benign and malignant breast lesions.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48428109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ketamine for treatment-resistant depression","authors":"Raad Madhloom","doi":"10.1016/c2019-0-02581-2","DOIUrl":"https://doi.org/10.1016/c2019-0-02581-2","url":null,"abstract":"","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41801467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Midgut volvulus with giant jejunal diverticulum in an elderly patient: Case report with literature review","authors":"H. Jasim","doi":"10.4103/mj.mj_44_20","DOIUrl":"https://doi.org/10.4103/mj.mj_44_20","url":null,"abstract":"Midgut volvulus is a rare cause of acute intestinal obstruction in elderly patients. It can be classified into primary (without obvious cause) or secondary (secondary to other abnormality). Jejunal diverticula are an uncommon type of diverticulum of the small bowel. However, associated with a high rate of complications such as diverticulitis, perforation, or rarely volvulus. In this case report, we present a female elderly patient with a proximal small bowel volvulus around the axis of superior mesenteric vessels with the giant jejunal diverticulum at the tip of the volvulus.","PeriodicalId":33069,"journal":{"name":"mjl@ lmstnSry@ lTby@","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45194277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}