2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE)最新文献_第4页

EEG-based automatic sleep-wake classification in humans using short and standard epoch lengths 基于脑电图的人类睡眠-觉醒自动分类，使用短和标准历元长度

2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE) Pub Date : 2012-11-11 DOI: 10.1109/BIBE.2012.6399688

Arnaud Brignol, T. Al-Ani, X. Drouot

{"title":"EEG-based automatic sleep-wake classification in humans using short and standard epoch lengths","authors":"Arnaud Brignol, T. Al-Ani, X. Drouot","doi":"10.1109/BIBE.2012.6399688","DOIUrl":"https://doi.org/10.1109/BIBE.2012.6399688","url":null,"abstract":"The alternating among sleep-wake stages gives information related to the sleep quality and quantity since this alternating pattern is highly affected during sleep disorders. The analysis of sleep in humans is usually made on periods (epochs) of 30-s length according to the original Rechtschaffen and Kales sleep scoring manual. In this paper, we propose a new phase space-based algorithm (mainly based on Poincaré plot) for automatic classification of sleep-wake states in humans using EEG data gathered over relatively short-time periods. The effectiveness of our approach is demonstrated through a series of experiments involving EEG data from seven healthy adult female subjects and was tested on epoch lengths ranging from 3-s to 30-s. The performance of our phase space approach was compared to a 2-dimensional state space approach using spectral power in two selected human-specific frequency bands. These powers were calculated by dividing integrated spectral amplitudes at selected human-specific frequency bands. The comparison demonstrated that the phase space approach gives better performance in the case of short as well as standard 30-s epoch lengths.","PeriodicalId":330164,"journal":{"name":"2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE)","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128533606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Video segmentation of the common carotid artery intima media complex 颈总动脉中内膜复合体的视频分割

2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE) Pub Date : 2012-11-11 DOI: 10.1109/BIBE.2012.6399728

C. Loizou, T. Kasparis, P. Papakyriakou, L. Christodoulou, M. Pantziaris, C. Pattichis

{"title":"Video segmentation of the common carotid artery intima media complex","authors":"C. Loizou, T. Kasparis, P. Papakyriakou, L. Christodoulou, M. Pantziaris, C. Pattichis","doi":"10.1109/BIBE.2012.6399728","DOIUrl":"https://doi.org/10.1109/BIBE.2012.6399728","url":null,"abstract":"The correct identification of the intima-media thickness (IMT) of the common carotid artery (CCA) walls has a high clinical relevance as it represents one of the most reliable predictor for future cardiovascular events. In this work we propose and evaluate an integrated system for the segmentation of the intima-media complex (IMC) and the lumen diameter in longitudinal ultrasound video of the CCA based on normalization, speckle reduction filtering (with a first order statistics filter) and snakes segmentation. The algorithm is initialized in the first video frame of the cardiac cycle by an automated initialization procedure and the borders of the far wall and near wall of the CCA are estimated. The IMC and the carotid diameter are then segmented automatically in the consecutive video frames for one cardiac cycle. The proposed algorithm was evaluated on 10 longitudinal ultrasound B-mode videos of the CCA and is compared with the manual tracings of a neurovascular expert, for every 20 frames in a time span of 3-5 seconds, covering in general 1-2 cardiac cycles. The algorithm estimated an IMTmean± standard deviation of (0.72±0.22) mm while the manual results were (0.70±0.19). The mean maximum and minimum diameter was (7.08±1.37) mm and (6.53±1.13) mm respectively. The results were validated based on statistical measures and univariate statistical analysis. It was shown that there was no significant difference between the snakes segmentation measurements and the manual measurements. The proposed integrated system could successfully segment the IMC in ultrasound CCA video sequences thus complementing manual measurements.","PeriodicalId":330164,"journal":{"name":"2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE)","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128894754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Image-based estimation of biomechanical relationship between masticatory muscle activities and mandibular movement 基于图像的咀嚼肌活动与下颌运动生物力学关系估计

2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE) Pub Date : 2012-11-11 DOI: 10.1109/BIBE.2012.6399749

Yang Yang, K. Foong, S. Ong, M. Yagi, K. Takada

{"title":"Image-based estimation of biomechanical relationship between masticatory muscle activities and mandibular movement","authors":"Yang Yang, K. Foong, S. Ong, M. Yagi, K. Takada","doi":"10.1109/BIBE.2012.6399749","DOIUrl":"https://doi.org/10.1109/BIBE.2012.6399749","url":null,"abstract":"Current techniques for investigating the functional roles of masticatory muscles are not suited to explaining subject-specific biomechanical relationship between mandibular movements and masticatory muscle activities. The aims of this study were to estimate the muscle tensions of subject-specific masticatory muscles in dental occlusion through the three-dimensional morphologic changes (3DMCs) of the muscles, and to explain the subject-specific biomechanical relationship between the mandibular movement and the muscle tensions. One healthy adult subject underwent magnetic resonance (MR) scans of the head at mandibular rest position (M0) and maximum intercuspation (M1). Based on the two sets of MR images, the mandibular movement was measured by the position changes of the mental protuberance of the mandible and the muscle tension from M0 to M1 for each masticatory muscle was estimated by its 3DMCs. The results showed the subject-specific biomechanical relationship between the mandibular movement and the muscle tensions, and the mandibular movement could be explained by these related muscle tensions anatomically and functionally.","PeriodicalId":330164,"journal":{"name":"2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE)","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122318646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Interactive binary active contours for prostate contour delineation 用于前列腺轮廓描绘的交互式二元活动轮廓

2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE) Pub Date : 2012-11-11 DOI: 10.1109/BIBE.2012.6399727

F. Derraz, L. Peyrodie, A. Taleb-Ahmed, G. Forzy

引用次数: 1

Antennas on metamaterial substrates as emitting components for THz biomedical imaging 超材料基板天线作为太赫兹生物医学成像发射元件

2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE) Pub Date : 2012-11-11 DOI: 10.1109/BIBE.2012.6399643

M. Koutsoupidou, N. Uzunoglu, I. Karanasiou

引用次数: 8

Medical guidelines reconciling medical software and electronic devices: Imatinib case-study 协调医疗软件和电子设备的医疗指南:伊马替尼案例研究

2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE) Pub Date : 2012-11-11 DOI: 10.1109/BIBE.2012.6399700

Alena Simalatsar, G. Micheli

{"title":"Medical guidelines reconciling medical software and electronic devices: Imatinib case-study","authors":"Alena Simalatsar, G. Micheli","doi":"10.1109/BIBE.2012.6399700","DOIUrl":"https://doi.org/10.1109/BIBE.2012.6399700","url":null,"abstract":"Nowadays medical software is tightly coupled with medical devices that perform patient state monitoring and lately even some basic treatment procedures. Medical guidelines (GLs) can be seen as specification of a medical system that includes both software and electronic devices. However, often medical GLs suffer from structural problems, such as incompleteness, inconsistencies, ambiguity and redundancy. Formal representation of GLs would enable the validation of GLs structural, real-time and life-cycle properties. Several GLs formal representation methods have been presented recently. Only some of them enable automatic formal verification by introducing an additional translation path to the existing model checking environments. However, if a verified property fails it is difficult to trace back the result needed to change the model. Moreover, these formalisms provide the notion of time mostly in terms of actions order. In this paper we preset a novel approach based on Timed Automata extended with Tasks (TAT) for the medical protocol formal representation using the TIMES toolbox. We discuss the verification issues with the help of the Imatinib case study.","PeriodicalId":330164,"journal":{"name":"2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE)","volume":"73 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128789703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Optimal anisotropic lead scaling of multichannel ECG to reduce magnitude signal variability 优化各向异性导联尺度的多通道心电信号减小幅度变异性

2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE) Pub Date : 2012-11-11 DOI: 10.1109/BIBE.2012.6399673

K. Noponen, T. Seppänen

引用次数: 0

Time-frequency analysis of heart rate variability for sleep and wake classification 睡眠和清醒分类的心率变异性时频分析

2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE) Pub Date : 2012-11-11 DOI: 10.1109/BIBE.2012.6399712

X. Long, P. Fonseca, R. Haakma, Ronald M. Aarts, J. Foussier

{"title":"Time-frequency analysis of heart rate variability for sleep and wake classification","authors":"X. Long, P. Fonseca, R. Haakma, Ronald M. Aarts, J. Foussier","doi":"10.1109/BIBE.2012.6399712","DOIUrl":"https://doi.org/10.1109/BIBE.2012.6399712","url":null,"abstract":"This paper describes a method to adapt the spectral features extracted from heart rate variability (HRV) for sleep and wake classification. HRV series can be derived from electrocardiogram (ECG) signals obtained from single-night polysomnography (PSG) recordings. Traditionally, the HRV spectral features are extracted from the spectrum of an HRV series with fixed boundaries specifying bands of very low frequency (VLF), low frequency (LF), and high frequency (HF). However, because they are fixed, they may fail to accurately reflect certain aspects of autonomic nervous activity, which in turn may limit their discriminative power when using HRV spectral features, e.g., in sleep and wake classification. This is in part related to the fact that the sympathetic tone (partially reflected in the LF band) and the respiratory activity (modulated in the HF band) will vary over time. In order to minimize the impact of these differences, we adapt the HRV spectral boundaries using time-frequency analysis. Experiments conducted on a dataset acquired from 15 healthy subjects show that the discriminative power of the adapted HRV spectral features are significantly increased when classifying sleep and wake. Additionally, this method also provides a significant improvement of the overall classification performance when used in combination with some other (non-spectral) HRV features.","PeriodicalId":330164,"journal":{"name":"2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE)","volume":"76 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131343880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 24

An image-based method for quantification of lateral pterygoid muscle deformation 一种基于图像的翼侧肌形变定量方法

2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE) Pub Date : 2012-11-11 DOI: 10.1109/BIBE.2012.6399752

Yang Yang, K. Foong, S. Ong, M. Yagi, K. Takada

{"title":"An image-based method for quantification of lateral pterygoid muscle deformation","authors":"Yang Yang, K. Foong, S. Ong, M. Yagi, K. Takada","doi":"10.1109/BIBE.2012.6399752","DOIUrl":"https://doi.org/10.1109/BIBE.2012.6399752","url":null,"abstract":"The aims of this study were to present a method quantifying and visualizing the deformation of subject-specific lateral pterygoid muscles (LPM) during a simulated jaw-opening movement. A normal adult male subject underwent magnetic resonance (MR) scans of the head at three mandibular positions: mandibular rest (M0), medium jaw-opened (M1), and maximum jaw-opened (M2) positions. The 3D models of the LPM were reconstructed from the three sets of MR images. The deformations of each muscle in the two cases (M0->;M1 and M1->;M2) were quantified in terms of the displacements of region correspondences between the muscle models before and after the mandibular position changed. The 3D models of the subject-specific LPM were reconstructed, and the directions and magnitudes of deformations of each muscle in the two cases were accurately quantified and visualized in the three anatomic planes. The functional activities along the entire body and at specific compartments of subject-specific LPM were quantified and visualised using the quantified 3D deformations of the LPM as a new descriptor. The presented method defined the deformations of the subject-specific LPM, and revealed the anatomic architectural and biomechanical characteristics of the subject-specific LPM appropriately and meaningfully in the simulated jaw-opening movement.","PeriodicalId":330164,"journal":{"name":"2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE)","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116356253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Measurement of motion of carotid bifurcation plaques 颈动脉分叉斑块运动的测量

2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE) Pub Date : 2012-11-11 DOI: 10.1109/BIBE.2012.6399729

Hamed Nasrabadi, M. Pattichis, A. Nicolaides, M. Griffin, G. Makris, Perry Fisher, E. Kyriacou, C. Pattichis

{"title":"Measurement of motion of carotid bifurcation plaques","authors":"Hamed Nasrabadi, M. Pattichis, A. Nicolaides, M. Griffin, G. Makris, Perry Fisher, E. Kyriacou, C. Pattichis","doi":"10.1109/BIBE.2012.6399729","DOIUrl":"https://doi.org/10.1109/BIBE.2012.6399729","url":null,"abstract":"Video loops of B-mode ultrasound images of 35 carotid bifurcation plaques were obtained (4 symptomatic and 31 asymptomatic) from patients with carotid bifurcation atherosclerosis. Video loops were classified visually as showing concordant (n=22) or discordant motion (n=13). Concordant plaques were characterized by uniform orientation of motion throughout the cardiac cycle. Discordant plaques exhibited significant spread in motion orientation at different parts of the cardiac cycle, especially at systole. We developed a real-time motion analysis system that applies Farneback's method to estimate velocities between consecutive video frames. For our purposes, we allow a 100msec time interval between the video frames used in the analysis. This approach allows us to analyze significant motions associated with a larger time interval. Over each video frame, we measure the spread of the motion orientation around the dominant orientation. For each video, we look at the spreads of the motion orientations for different motion magnitudes. Using these motion-spread measurements, we can quantify discordant movement. The sum of maximum fan widths for the median pixel motions 5 to 3 (SMFW5to3) had a median value of 100 degrees and interquartile range (IQR) of (80, 110) degrees for the concordant plaques and 270, (230, 430) for the discordant plaques (P <; 0.001). Thus, we have a new tool to differentiate between concordant and discordant plaques.","PeriodicalId":330164,"journal":{"name":"2012 IEEE 12th International Conference on Bioinformatics & Bioengineering (BIBE)","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115685356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10