{"title":"Comment on: Patient experiences with laparoscopic incisions under enhanced recovery after surgery protocols","authors":"Haseeb Safdar Ali","doi":"10.1016/j.lers.2025.10.003","DOIUrl":"10.1016/j.lers.2025.10.003","url":null,"abstract":"","PeriodicalId":32893,"journal":{"name":"Laparoscopic Endoscopic and Robotic Surgery","volume":"9 1","pages":"Pages 56-57"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147414324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gaetano Ciancio , Jeffrey J. Gaynor , Mahmoud Morsi , Giselle Guerra , Javier Gonzalez , Armando Salim Munoz Abraham , Adela Mattiazzi , Franco H. Cabeza , Angel Alvarez , Matthew Gaynor , Rodrigo Vianna
{"title":"Robotic-assisted living donor nephrectomy in open kidney transplantation: Our clinical experience","authors":"Gaetano Ciancio , Jeffrey J. Gaynor , Mahmoud Morsi , Giselle Guerra , Javier Gonzalez , Armando Salim Munoz Abraham , Adela Mattiazzi , Franco H. Cabeza , Angel Alvarez , Matthew Gaynor , Rodrigo Vianna","doi":"10.1016/j.lers.2025.11.003","DOIUrl":"10.1016/j.lers.2025.11.003","url":null,"abstract":"<div><h3>Objective</h3><div>Robotic-assisted living donor nephrectomy (RALDN) has been shown to be a safe and feasible option, offering enhanced visualization and improved surgical dexterity, allowing for a potential increase in the living donor pool to perform pediatric and adult kidney transplants, even in cases of grafts with anatomical variants. We report our recent experience in using RALDN for open kidney transplantation (OKT).</div></div><div><h3>Methods</h3><div>Between August 2021 and July 2025, 122 kidney transplant recipients underwent OKT using RALDN grafts obtained at the Miami Transplant Institute. Clinical outcomes, during the first 12 months post-transplant, including the incidence of delayed graft function (DGF), surgical complications, estimated glomerular filtration rate (eGFR), and graft loss, were evaluated.</div></div><div><h3>Results</h3><div>Sixteen pediatric and 106 adult recipients were included. The median recipient and donor ages were 42.2 yr and 39.5 yr, respectively. Male recipients comprised 63.1% (77/122); female donors comprised 56.6% (69/122). Among the donors, no conversion to open surgery was needed, and no post-operative complications attributed to the RALDN procedure were observed. Thirty-one kidney grafts required back table reconstruction. The median cold and warm ischemia times were 55.5 min and 27.0 min, respectively. One case (0.8%) of DGF was observed. One recipient (0.8%) developed a post-operative vascular complication; five (4.1%) developed a urologic complication. The median eGFRs at 1 mo, 3 mo, 6 mo, and 12 mo post-transplant were 71.9, 77.1, 75.1, and 72.1 mL/min/1.73 m<sup>2</sup>, respectively. No cases of graft failure during the first 12 months post-transplant were observed, and one patient died with a functioning graft.</div></div><div><h3>Conclusion</h3><div>RALDN is a safe and effective technique that provides favorable outcomes among both donors and recipients. This minimally invasive approach should be offered as a safe alternative to living donor patients.</div></div>","PeriodicalId":32893,"journal":{"name":"Laparoscopic Endoscopic and Robotic Surgery","volume":"9 1","pages":"Pages 16-22"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147414586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aswin Shanmugalingam , Joseph Do Woong Choi , Ali Mohtashami , Kar Yin Fok , Praveen Ravindran , Andrew Craig Lynch , Stephen Pillinger
{"title":"Comparative analysis of surgical inflammatory response with C-reactive protein post robotic versus laparoscopic elective colorectal resection for colorectal tumour","authors":"Aswin Shanmugalingam , Joseph Do Woong Choi , Ali Mohtashami , Kar Yin Fok , Praveen Ravindran , Andrew Craig Lynch , Stephen Pillinger","doi":"10.1016/j.lers.2026.01.001","DOIUrl":"10.1016/j.lers.2026.01.001","url":null,"abstract":"<div><h3>Objective</h3><div>Robotic colorectal surgery (RCS) provides a stable, magnified three-dimensional visual field and enhanced ergonomics enabling precise dissection and tremor suppression. We postulate that this technique is associated with less tissue trauma and improved postoperative outcomes than laparoscopic colorectal surgery (LCS). This study aimed to explore the inflammatory response following RCS by measuring postoperative C-reactive protein (CRP) levels and compare them with LCS data reported in the literature.</div></div><div><h3>Methods</h3><div>This single centre retrospective study included consecutive elective robotic colon and rectum resections via the da Vinci® Xi platform for benign and malignant colorectal tumours, performed by a single surgeon between January 2017 and December 2023 at the Sydney Adventist Hospital, Sydney. CRP values were measured on post-operative days (PODs) 3 and 5. A narrative review of the literature was performed via EMBASE, MEDLINE via PubMed and Google Scholar from inception to December 2024 for comparative CRP values following LCS. Descriptive statistical comparisons were performed between the RCS and LCS.</div></div><div><h3>Results</h3><div>One hundred ninety-three patients were identified in the RCS cohort. The median age was 73 y (range: 62–83 y). Most colectomies were performed for adenocarcinoma (90.2%), with right hemicolectomy being the most common type of procedure (49.3%). The median CRP levels on PODs 3 and 5 were 83.10 mg/L (IQR: 49.80–124.12 mg/L) and 26.20 mg/L (IQR: 17.70–80.00 mg/L), respectively. The reported CRP after LCS was heterogeneous, with mean POD 3 values ranging from 69 mg/L to 99.5 mg/L, and mean POD 4–5 values ranging from 62.4 mg/L to 72.85 mg/L.</div></div><div><h3>Conclusions</h3><div>There were similar, if not lower, POD 3 and 5 CRP values, suggesting that RCS was probably non-inferior to LCS regarding postoperative tissue trauma. In particular, there appeared to be a quicker recovery of the inflammatory response with RCS.</div></div>","PeriodicalId":32893,"journal":{"name":"Laparoscopic Endoscopic and Robotic Surgery","volume":"9 1","pages":"Pages 29-33"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147414326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Boming Xia , Chengqiao Jiang , Jie Yang , Suibi Yang , Bo Zhang , Zhihao Wang , Shengze Wu , Yang Wang , Qian Gao , Yucai Hong , Huiqing Ge , Zhongheng Zhang
{"title":"Longitudinal trajectory analysis of sepsis after laparoscopic surgery","authors":"Boming Xia , Chengqiao Jiang , Jie Yang , Suibi Yang , Bo Zhang , Zhihao Wang , Shengze Wu , Yang Wang , Qian Gao , Yucai Hong , Huiqing Ge , Zhongheng Zhang","doi":"10.1016/j.lers.2025.11.004","DOIUrl":"10.1016/j.lers.2025.11.004","url":null,"abstract":"<div><h3>Objective</h3><div>Sepsis exhibits remarkable heterogeneity in disease progression trajectories, and accurate identification of distinct trajectory-based phenotypes is critical for implementing personalized therapeutic strategies and prognostic assessment. However, trajectory clustering analysis of time-series clinical data poses substantial methodological challenges for researchers. This study provides a comprehensive tutorial framework demonstrating six trajectory modeling approaches integrated with proteomic analysis to guide researchers in identifying sepsis subtypes after laparoscopic surgery.</div></div><div><h3>Methods</h3><div>This study employs simulated longitudinal data from 300 septic patients after laparoscopic surgery to demonstrate six trajectory modeling methods (group-based trajectory modeling, latent growth mixture modeling, latent transition analysis, time-varying effect modeling, K-means for longitudinal data, agglomerative hierarchical clustering) for identifying associations between predefined sequential organ failure assessment trajectories and 25 proteomic biomarkers. Clustering performance was evaluated via multiple metrics, and a biomarker discovery pipeline integrating principal component analysis, random forests, feature selection, and receiver operating characteristic analysis was developed.</div></div><div><h3>Results</h3><div>The six methods demonstrated varying performance in identifying trajectory structures, with each approach exhibiting distinct analytical characteristics. The performance metrics revealed differences across methods, which may inform context-specific method selection and interpretation strategies.</div></div><div><h3>Conclusion</h3><div>This study illustrates practical implementations of trajectory modeling approaches under controlled conditions, facilitating informed method selection for clinical researchers. The inclusion of complete R code and integrated proteomics workflows offers a reproducible analytical framework connecting temporal pattern recognition to biomarker discovery. Beyond sepsis, this pipeline-oriented approach may be adapted to diverse clinical scenarios requiring longitudinal disease characterization and precision medicine applications. The comparative analysis reveals that each method has distinct strengths, providing a practical guide for clinical researchers in selecting appropriate methods based on their specific study goals and data characteristics.</div></div>","PeriodicalId":32893,"journal":{"name":"Laparoscopic Endoscopic and Robotic Surgery","volume":"9 1","pages":"Pages 34-51"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147414584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Peter McNicholas, Freddy Kattakayam, Joshua Hemmant, Robin Weston, Vishwanath Hanchanale
{"title":"A systematic review of open versus robotic retroperitoneal lymph node dissection for testicular cancer: Comparative operative and oncological outcomes","authors":"Daniel Peter McNicholas, Freddy Kattakayam, Joshua Hemmant, Robin Weston, Vishwanath Hanchanale","doi":"10.1016/j.lers.2026.01.002","DOIUrl":"10.1016/j.lers.2026.01.002","url":null,"abstract":"<div><h3>Objective</h3><div>Open retroperitoneal lymph node dissection (RPLND) is the gold-standard surgical approach for the management of metastatic testicular cancer, but robotic RPLND is becoming increasingly popular. There is limited research directly comparing open and robotic RPLND. The objective of this systematic review is to identify all the literature with direct comparisons between the open and robotic techniques for RPLND and to compare the two techniques. The primary outcome was peri-operative outcomes, and the secondary outcomes included oncological outcomes and patient demographics.</div></div><div><h3>Methods</h3><div>This systematic review was prospectively registered and was conducted in accordance with the PRISMA statement. The PubMed, Embase and MEDLINE databases were searched for relevant publication from January 2006 to August 2024.</div></div><div><h3>Results</h3><div>Eight studies, totaling 3995 patients, are included in this systematic review, with 3521 patients who underwent open RPLND and 474 who underwent robotic RPLND. For open RPLND, the mean operative duration, blood loss and length of stay were 267.8 min, 475 mL and 7.3 d, respectively. For robotic RPLND, the mean operative duration, blood loss and length of stay were 334.5 min, 94.6 mL and 3.7 d, respectively. Teratoma was the most common RPLND specimen pathology from both open and robotic surgeries. For open RPLND, the specimens have 13–23 nodes (26–32 mm), whereas the robotic RPLND specimens have 13–28 nodes (18–20 mm).</div></div><div><h3>Conclusion</h3><div>This systematic review suggests that the benefits of robotic RPLND may be associated with reduced blood loss, shorter hospitalisation and an overall lower risk of minor and major complications while maintaining oncological safety.</div></div>","PeriodicalId":32893,"journal":{"name":"Laparoscopic Endoscopic and Robotic Surgery","volume":"9 1","pages":"Pages 1-7"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147414585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alberto G. Barranquero , Loreto Martín Ferrero , Laia Codina Corrons , Yolanda Maestre González , Cristina Gas Ruiz , Alfredo Escartín Arias , Rafael Villalobos Mori
{"title":"Robotic or laparoscopic inguinal hernia repair? A narrative review of the current literature","authors":"Alberto G. Barranquero , Loreto Martín Ferrero , Laia Codina Corrons , Yolanda Maestre González , Cristina Gas Ruiz , Alfredo Escartín Arias , Rafael Villalobos Mori","doi":"10.1016/j.lers.2025.12.001","DOIUrl":"10.1016/j.lers.2025.12.001","url":null,"abstract":"<div><div>Robotic inguinal hernia repair remains in the early stages of implementation, and its potential advantages over the laparoscopic approach are still a matter of debate. This narrative review aims to summarize the findings of major systematic reviews and randomized controlled trials and explore variables not adequately addressed in those studies. The literature review indicates that robotic inguinal hernia repair is associated with longer operative times but has improved ergonomics compared with laparoscopy. It is a safe procedure that results in a reduced inflammatory response, similar complication rates, and no significant difference in acute postoperative pain. Although it involves higher direct costs, its cost-effectiveness remains unclear owing to a lack of analysis including indirect costs. Ongoing controversy continues regarding long-term benefits. The most recent systematic review pointed towards lower recurrence rates with robotic surgery, although randomized controlled trials have not validated this finding. Data on chronic pain are currently insufficient to draw firm conclusions. Further studies are needed to assess its use in complex cases and the role of novel techniques.</div></div>","PeriodicalId":32893,"journal":{"name":"Laparoscopic Endoscopic and Robotic Surgery","volume":"9 1","pages":"Pages 8-15"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147414587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Laparoscopic ureterolithotomy combined with flexible cystoscopy for the treatment of large impacted ureteral calculi with renal stones","authors":"Zhenghui Wang, Mingchao Wang, Jie Yuan, Liwei Xu","doi":"10.1016/j.lers.2025.09.001","DOIUrl":"10.1016/j.lers.2025.09.001","url":null,"abstract":"","PeriodicalId":32893,"journal":{"name":"Laparoscopic Endoscopic and Robotic Surgery","volume":"9 1","pages":"Pages 52-55"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147414325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuzhang Li , Khadija Hasan , Wenmin Yu , Xingyu Lai , Bin Zheng
{"title":"Addressing disorientation in endoscopy: A study on mental rotation difficulty and its impact on cognitive load measured by pupillary response","authors":"Yuzhang Li , Khadija Hasan , Wenmin Yu , Xingyu Lai , Bin Zheng","doi":"10.1016/j.lers.2025.07.004","DOIUrl":"10.1016/j.lers.2025.07.004","url":null,"abstract":"<div><h3>Objectives</h3><div>One of the most notable challenges in endoscopic procedures is maintaining correct orientation. Mental rotation exercise (MRE) has been suggested as a potential aid for improving orientation. However, there is a lack of research on designing MREs with varying difficulty levels for training purposes. Furthermore, few studies provide solid evidence linking MRE difficulty levels with cognitive load measurements. This study aims to address this gap by investigating the correlation between the MRE difficulty levels and participants’ cognitive load, as measured by pupil dilation.</div></div><div><h3>Method</h3><div>We recruited 33 participants to perform MREs on a computer equipped with a screen-mounted eye-tracker. The test consisted of 15 MREs, with the first 10 relatively easy (traditional cube) and the next 5 more complex (invented molecule). The participants’ eye movements during MREs were recorded. The participants’ MRE scores and pupil dilation were obtained and compared between two MRE difficulty levels.</div></div><div><h3>Results</h3><div>The participants who performed traditional cube MREs achieved significantly better MRE scores (0.77 ± 0.11 vs. 0.58 ± 0.03, <em>p</em> < 0.001) and lower pupil dilation (0.27 ± 0.04 pixels vs. 0.47 ± 0.09 pixels, <em>p</em> < 0.001) than did those who performed the invented molecule MREs. Moreover, there were significant negative correlations (<em>r</em> = −0.62, <em>p</em> = 0.015) between pupil dilation and MRE scores.</div></div><div><h3>Conclusions</h3><div>The results revealed a significant negative correlation between MRE scores and pupil dilation. The more challenging MRE questions led to worse MRE scores but increased pupil dilation. The MRE difficulty levels can be evaluated not only by the degrees or dimensions with which the objects were rotated but also by the participants’ MRE scores and pupil dilation. The results of this study provide a basis for training orientation skills in endoscopy using MREs. By incorporating MREs with varying difficulty levels, customized training programs can be developed to enhance camera navigation in endoscopic and laparoscopic procedures.</div></div>","PeriodicalId":32893,"journal":{"name":"Laparoscopic Endoscopic and Robotic Surgery","volume":"9 1","pages":"Pages 23-28"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147414589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Thank you to Laparoscopic, Endoscopic and Robotic Surgery peer reviewers","authors":"Qingjie Zeng, Jin Wang","doi":"10.1016/j.lers.2025.12.002","DOIUrl":"10.1016/j.lers.2025.12.002","url":null,"abstract":"","PeriodicalId":32893,"journal":{"name":"Laparoscopic Endoscopic and Robotic Surgery","volume":"9 1","pages":"Pages 62-63"},"PeriodicalIF":2.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147414313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}