The cost–efficiency of preoperative phenazopyridine use in ureteral jet visualization at time of cystoscopy following minimally invasive hysterectomy

IF 2 Q3 Medicine

Laparoscopic Endoscopic and Robotic Surgery Pub Date : 2025-07-10 DOI:10.1016/j.lers.2025.07.001

Caitlin H. Waters , Maame Yaa Brako , Heidi Preis , Lokesh Patil , Nicole Massad , Jennifer Blaber , Sara Kim , Xun Lian

{"title":"The cost–efficiency of preoperative phenazopyridine use in ureteral jet visualization at time of cystoscopy following minimally invasive hysterectomy","authors":"Caitlin H. Waters , Maame Yaa Brako , Heidi Preis , Lokesh Patil , Nicole Massad , Jennifer Blaber , Sara Kim , Xun Lian","doi":"10.1016/j.lers.2025.07.001","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>To determine the impact of planned preoperative phenazopyridine administration on operative times and costs compared with as-needed intravenous agent use during routine cystoscopy following minimally invasive hysterectomy for benign indications.</div></div><div><h3>Method</h3><div>This prospective cohort study examined patients who underwent laparoscopic or robotic-assisted total or supracervical hysterectomy for benign indications between January 27, 2023 and March 11, 2024, with one of our minimally invasive gynecologic surgeons at Stony Brook University Hospital. Patients were assigned to the non-phenazopyridine group or the phenazopyridine group. The time needed to visualize the ureteral jets during cystoscopy and the total surgery duration were recorded. A cost analysis was then performed.</div></div><div><h3>Results</h3><div>In total, 106 patients were included, with 53 patients in each group. Compared with the non-phenazopyridine group, the phenazopyridine group had significantly shorter times from the start of cystoscopy to visualization of the first ureteral jet (31 s vs. 42 s, <em>p</em> < 0.05). However, there were no significant differences observed for visualization of the second jet, total jet time, or surgery duration. Two patients in the non-phenazopyridine group required the administration of intravenous agents intraoperatively. Routine phenazopyridine was found to be more cost-efficient when medication costs and operative times were examined.</div></div><div><h3>Conclusion</h3><div>Routine phenazopyridine use does not significantly shorten overall cystoscopy times, but it is the more cost-efficient option given increased rates of costly intravenous medication use in the non-phenazopyridine group.</div></div>","PeriodicalId":32893,"journal":{"name":"Laparoscopic Endoscopic and Robotic Surgery","volume":"8 3","pages":"Pages 128-133"},"PeriodicalIF":2.0000,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Laparoscopic Endoscopic and Robotic Surgery","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2468900925000465","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Objective

To determine the impact of planned preoperative phenazopyridine administration on operative times and costs compared with as-needed intravenous agent use during routine cystoscopy following minimally invasive hysterectomy for benign indications.

Method

This prospective cohort study examined patients who underwent laparoscopic or robotic-assisted total or supracervical hysterectomy for benign indications between January 27, 2023 and March 11, 2024, with one of our minimally invasive gynecologic surgeons at Stony Brook University Hospital. Patients were assigned to the non-phenazopyridine group or the phenazopyridine group. The time needed to visualize the ureteral jets during cystoscopy and the total surgery duration were recorded. A cost analysis was then performed.

Results

In total, 106 patients were included, with 53 patients in each group. Compared with the non-phenazopyridine group, the phenazopyridine group had significantly shorter times from the start of cystoscopy to visualization of the first ureteral jet (31 s vs. 42 s, p < 0.05). However, there were no significant differences observed for visualization of the second jet, total jet time, or surgery duration. Two patients in the non-phenazopyridine group required the administration of intravenous agents intraoperatively. Routine phenazopyridine was found to be more cost-efficient when medication costs and operative times were examined.

Conclusion

Routine phenazopyridine use does not significantly shorten overall cystoscopy times, but it is the more cost-efficient option given increased rates of costly intravenous medication use in the non-phenazopyridine group.

查看原文本刊更多论文

微创子宫切除术后膀胱镜检查输尿管射孔时术前应用非那吡啶的成本效益

目的比较良性微创子宫切除术后常规膀胱镜检查时，术前计划给药非那吡啶与按需静脉给药对手术时间和费用的影响。方法本前瞻性队列研究调查了2023年1月27日至2024年3月11日期间在石溪大学医院接受腹腔镜或机器人辅助全子宫切除术或宫颈上子宫切除术的良性指征患者。患者被分为非那唑吡啶组和非那唑吡啶组。记录膀胱镜观察输尿管射孔所需时间及手术总时间。然后进行成本分析。结果共纳入106例患者，每组53例。与非那唑吡啶组相比，非那唑吡啶组从膀胱镜检查开始到输尿管第一射道可见的时间明显缩短(31 s vs. 42 s, p <；0.05)。然而，在第二次喷射的可视化、总喷射时间或手术持续时间方面，没有观察到显著差异。非那唑吡啶组2例患者需要术中静脉注射药物。当检查药物费用和手术时间时，发现常规非那吡啶更具成本效益。结论常规使用非那氮吡啶并不能显著缩短膀胱镜检查总时间，但在非那氮吡啶组，由于昂贵的静脉药物使用率增加，常规使用非那氮吡啶是更经济有效的选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Laparoscopic Endoscopic and Robotic Surgery minimally invasive surgery-

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： Laparoscopic, Endoscopic and Robotic Surgery aims to provide an academic exchange platform for minimally invasive surgery at an international level. We seek out and publish the excellent original articles, reviews and editorials as well as exciting new techniques to promote the academic development. Topics of interests include, but are not limited to: ▪ Minimally invasive clinical research mainly in General Surgery, Thoracic Surgery, Urology, Neurosurgery, Gynecology & Obstetrics, Gastroenterology, Orthopedics, Colorectal Surgery, Otolaryngology, etc.; ▪ Basic research in minimally invasive surgery; ▪ Research of techniques and equipments in minimally invasive surgery, and application of laparoscopy, endoscopy, robot and medical imaging; ▪ Development of medical education in minimally invasive surgery.