Journal of Current Research in Scientific Medicine最新文献

{"title":"Effect of preoperative anxiety on postoperative pain in patients undergoing elective lower-segment cesarean section under spinal anesthesia: A cross-sectional study in South India","authors":"Y. Suresh, Aswini Lakshminarasimhan","doi":"10.4103/jcrsm.jcrsm_39_22","DOIUrl":"https://doi.org/10.4103/jcrsm.jcrsm_39_22","url":null,"abstract":"Background: Anxiety is often encountered but overlooked in patients undergoing elective surgery. Anxiety may influence the perception of postoperative pain which is one of the major concerns for all patients. This study aimed to evaluate the effect of preoperative anxiety on postoperative pain and to find if any relation exists between demographic variables and anxiety in cesarean patients. Methodology: One hundred and twelve patients undergoing elective cesarean section under spinal anesthesia were evaluated for preoperative anxiety on the day before surgery using the Amsterdam Preoperative Anxiety and Information Scale questionnaire-based face-to-face interview, and postoperative pain was recorded every 6 h after surgery for 24 h using the Visual Analog Scale (VAS). Results: The prevalence of preoperative anxiety in the study subjects was 36%. The need for high information was 22%. The mean for anesthesia-related anxiety, information desire component, combined anxiety score, and VAS scores was 4.21 ± 2.63, 3.23 ± 2.15, 8.72 ± 4.60, and 5.30 ± 1.86, respectively. Postoperative pain was found to be correlating with higher levels of preoperative anxiety (r = 0.25, P < 0.01). Information desire component was found to have a positive, moderate, and significant correlation with anxiety score (r = 0.49, P < 0.01). No statistically significant relationship was found between sociodemographic characteristics and preoperative anxiety. Conclusion: This study demonstrated a positive and statistically significant correlation between preoperative anxiety and postoperative pain. Well-conducted randomized controlled studies are required to determine whether reducing anxiety before a surgery results in reduced postoperative pain response. Anxiety-reducing measures can be employed throughout the preoperative period in the surgical population to reduce postoperative pain in addition to analgesics.","PeriodicalId":32638,"journal":{"name":"Journal of Current Research in Scientific Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90986481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antimicrobial resistance surveillance among patients with sepsis in intensive care units of a tertiary care center","authors":"KSandhya Bhat, C. Sanjeevan","doi":"10.4103/jcrsm.jcrsm_28_22","DOIUrl":"https://doi.org/10.4103/jcrsm.jcrsm_28_22","url":null,"abstract":"Background: Rising antimicrobial resistance (AMR) rate is a challenge for treating patients in health-care settings globally. Most intensive care unit (ICU) patients are frequently on antimicrobial agents; this induces selective antibiotic pressure and increases the threat of the development of AMR. The objective of this study was to document the microbiological profile and antimicrobial susceptibility pattern of the isolates from blood culture-confirmed cases of sepsis from ICUs at a tertiary care center. Materials and Methods: A retrospective data collection was conducted after obtaining a waiver of consent from the institute ethics committee. A total of 151 patients, aged 18 years and above, admitted to the ICUs between January and December 2019 with blood culture-proven sepsis were included in the study. Data on demographic details, ICU stay, underlying risk factors, infecting organisms, and antimicrobial susceptibility reports were collected and analyzed using Microsoft Excel. Results: A total of 1020 clinically suspected sepsis patients were admitted to the ICUs during the study period. Of these, 151 patients (14.8%) had blood culture-proven sepsis. Gram-negative bacteria were the most frequent isolates (63.6%), among which Escherichia coli was the most common pathogen (25%), followed by Klebsiella pneumoniae (15%), and Acinetobacter baumannii (13.6%). The rate of resistance was more against cephalosporins as compared to carbapenems and tigecycline. Commonly documented gram-positive bacterial isolates were coagulase-negative staphylococci (8.6%), viridans streptococci (7.1%), and Staphylococcus aureus (5%). About 65.2% of penicillin-resistance and 15.8% of methicillin-resistant staphylococci were documented. Conclusion: This study on AMR was useful to know the prevalence of sepsis among ICU inpatients and the microbiological profile with their AMR pattern in our tertiary care hospital. This may help to generate local antibiograms which may further contribute to formulating the national data. Based on available antibiogram data, the choice of antibiotics for empiric treatment becomes easier. It may also guide the clinicians to escalate or de-escalate the antibiotics wherever possible.","PeriodicalId":32638,"journal":{"name":"Journal of Current Research in Scientific Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73888747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mucinous cystadenoma in a 15-year-old girl: An incidental finding","authors":"M. Rashmi, A. Bhaskar","doi":"10.4103/jcrsm.jcrsm_37_22","DOIUrl":"https://doi.org/10.4103/jcrsm.jcrsm_37_22","url":null,"abstract":"Ovarian tumors in children and adolescents are rare. We present a case of a 15-year-old girl with mucinous cystadenoma (MCA) which was diagnosed incidentally when evaluating for anemia and reduced appetite. The scan reports suggested a large ovarian cyst with a few thick enhancing septa. Serological markers were within normal limits. She underwent a cystectomy with salpingo-oophorectomy. The cyst was reported as MCA on histopathology. The child is on regular follow-up for 6 months with no adverse events.","PeriodicalId":32638,"journal":{"name":"Journal of Current Research in Scientific Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80252532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical spectrum and Cytogenetic characterization of patients with Turner Syndrome – Twin case report","authors":"Sriambika Kumar, Rema Devi","doi":"10.4103/jcrsm.jcrsm_71_21","DOIUrl":"https://doi.org/10.4103/jcrsm.jcrsm_71_21","url":null,"abstract":"Diagnosis of Turner syndrome (TS) is usually made in mid-childhood, where 50% of the patients have 45, X karyotype in peripheral lymphocytes, which results from haploinsufficiency of the genes that commonly escape X-inactivation. 30%–40% have mosaicism of different forms, like 45,X/46,X,dic(Xp)/46,X,idic(Xq) and less commonly 45,X/46,XY. The goal of this case report is to analyze the cytogenetic and molecular characterization of two cases with dicentric X chromosomal abnormalities with varying degrees of mosaicism, demonstrating shared clinical features of TS. Combined conventional cytogenetic analysis, centromere banding, and fluorescence in situ hybridization (FISH) was done for the patients who presented with short stature and irregular menstrual cycles. Chromosome studies showed two cell lines: one with a single copy of X chromosome (45,X) and the other with a structural variation in X chromosome (isodicentric X chromosome), which is described as a Turner variant. C-banding also revealed the presence of two centromeres. Metaphase FISH with centromere probes for X revealed two mosaic cell lines: one with 45,X and a second one showing isodicentric X chromosome. The accurate diagnosis and characterization of a genomic imbalance in patients with sex chromosome disorders are essential for evaluating phenotype–karyotype correlations, genetic counseling, and having a clinical follow-up.","PeriodicalId":32638,"journal":{"name":"Journal of Current Research in Scientific Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88875425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Alveolar-Arterial Oxygen Pressure Difference be used to Diagnose Acute Respiratory Distress Syndrome in Pneumonia Patients?","authors":"Ling Wang, Wanling Wang","doi":"10.14302/issn.2766-8681.jcsr-22-4162","DOIUrl":"https://doi.org/10.14302/issn.2766-8681.jcsr-22-4162","url":null,"abstract":"Alveolar-arterial oxygen pressure difference (P(Aa)O2) can reflect pulmonary ability to exchange oxygen; it shows good correlation with the oxygenation index (OI), which is important in diagnosing acute respiratory distress syndrome (ARDS). This study explored the ability of P(Aa)O2 in diagnosing ARDS in pneumonia patients.\u0000\u0000Methods\u0000We selected patients with community-acquired pneumonia and sepsis in the intensive care unit (ICU) of the People’s Hospital of Qiandongnan Miao and Dong Autonomous Prefecture; we measured P(Aa)O2 and the OI under anoxic conditions upon their admittance to the ICU. We divided the patients into ARDS and non-ARDS groups. We compared the differences in P(Aa)O2 and OI; we analyzed the correlation between P(Aa)O2 and ARDS. To assess the diagnostic ability of P(Aa)O2 for ARDS, we drew the receiver operating characteristic (ROC) curve.\u0000\u0000Result\u0000We found that P(Aa)O2 in the ARDS group was greater than in the non-ARDS group (t = 8.875, P <0.001); the OI in the ARDS group was smaller than in the non-ARDS group (t = –6.956, P <0.001). There was a positive correlation between P(Aa)O2 and ARDS (r = 0.718, P <0.001). The area under the ROC curve for P(Aa)O2 in the diagnosis of ARDS was 0.931 (0.873–0.988); the cutoff value was 214.70 mmHg, the sensitivity was 89.50%, and the specificity was 85.00%.\u0000\u0000Conclusion\u0000We conclude that P(Aa)O2 is a good reference index in diagnosing ARDS","PeriodicalId":32638,"journal":{"name":"Journal of Current Research in Scientific Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79936124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design of Stopwatch based on STC89C52 Single Chip Microcomputer","authors":"Wen Wang, Yongjian Sun","doi":"10.14302/issn.2766-8681.jcsr-22-4126","DOIUrl":"https://doi.org/10.14302/issn.2766-8681.jcsr-22-4126","url":null,"abstract":"This design is according to the requirements of the wide rider, and the Multi-function bike computer has the function of velocity measurement, display, timing, lighting, buzzer warning, which could satisfy the requirements of cycling enthusiasts. This design is based on STC89C52 SCM (Single Chip Microcomputer) smallest system and uses hall sensor receives the bicycle wheel rotation numbers date, and then transmit the received data into the SCM. After the SCM’s calculation and processing, it gets the bicycle’s instantaneous speed, mileage, riding time through the LED display the date. The part of software programming use C language, which compiles and downloads by the Keil and STC-ISP. This design uses Proteus to make the circuit diagram drawing and system simulation. The overall program adopted modular approach, and each module has a special function. The idea which makes the program more clear, is advantageous to the optimization of code logic and modification.","PeriodicalId":32638,"journal":{"name":"Journal of Current Research in Scientific Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87271890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional State Hardware Evaluation System in Educational Medium","authors":"Evgeny Moos, Elena V. Moos","doi":"10.14302/issn.2766-8681.jcsr-21-3762","DOIUrl":"https://doi.org/10.14302/issn.2766-8681.jcsr-21-3762","url":null,"abstract":"Diagnosis of heart rate variability as an indicator of the impact of external and internal media can serve to make changes in the educational environment. The approach to the organization of the educational process is developed on the basis of quantitative indicators of the students’ functional state using the hardware-software complex \" Varikard \".","PeriodicalId":32638,"journal":{"name":"Journal of Current Research in Scientific Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90259712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of biomarkers in predicting the severity and mortality of coronavirus disease 2019 infection: A retrospective observational study","authors":"Sapna S Deshpande, Namrata B Mestri, M. Halgale, Pradnya M Chimankar","doi":"10.4103/jcrsm.jcrsm_72_21","DOIUrl":"https://doi.org/10.4103/jcrsm.jcrsm_72_21","url":null,"abstract":"Context: The clinical course of Coronavirus Disease 2019 (COVID-19) infection is variable and subjective. Hence, there is a dire need for objective interpretation of severity. The utilization of biomarkers categorizes these patients into nonsevere, severe, or critical categories. Aim: This study aims to assess the role of different biomarkers in predicting the severity and mortality of COVID 19. Materials and Methods: Case records of 247 patients of a designated COVID center in Kolhapur, Maharashtra, India, were included in this observational study. Biomarkers such as total leukocyte count, C-reactive protein, lactate dehydrogenase, D-Dimer, interleukin-6 (IL-6), procalcitonin, and serum ferritin were studied in different categories of severity of the disease. Results: The median serum ferritin levels among nonsevere cases, severe, and critical cases were 187.95 ng/mL (interquartile range [IQR] = 93.05 ng/mL to 382.50 ng/mL), 230 ng/mL (156 ng/mL to 670 ng/mL), and 412.33 ng/mL (234 ng/mL to 689 ng/mL), respectively and this difference was statistically significant (P < 0.001). The average values of IL-6 were significantly higher (P < 0.001) among the patients who died (19.12 pg/mL) when compared to those which were alive (3.74 pg/mL). Based on the receiver operating characteristic analysis, the interpretation of the severity of the disease was excellent through the evaluation of levels of serum ferritin (Area under curve = 0.755 [95% confidence interval = 0.635–0.875; P = 0.001]). Conclusions: Serum ferritin among the biomarker panel studied was the best test that predicted the severity of COVID-19 infection. The IL-6 levels were significantly higher among the patient who succumbed when compared to those who survived the disease.","PeriodicalId":32638,"journal":{"name":"Journal of Current Research in Scientific Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72748624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pedestrian fatality: Price paid for zero individual travel carbon footprint!!","authors":"A. Radjou, Muthandavn Uthrapathy, S. Sevel, G. Sriramulu","doi":"10.4103/2455-3069.350137","DOIUrl":"https://doi.org/10.4103/2455-3069.350137","url":null,"abstract":"","PeriodicalId":32638,"journal":{"name":"Journal of Current Research in Scientific Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72435078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative study of students' perception of flipped classroom teaching and traditional classroom teaching among final-year medical students","authors":"Kavitha Balasubramanian, Vinoth Kumar Sethuraman, Balasubramanian Ramachandran","doi":"10.4103/jcrsm.jcrsm_69_21","DOIUrl":"https://doi.org/10.4103/jcrsm.jcrsm_69_21","url":null,"abstract":"Introduction: Recently, flipped classrooms (FCs) have emerged as a new pedagogical method in which students are given study resource material to develop a basic understanding of the topic before class, and in-class precious time is used for learner-centric activities. Accordingly, the study objective was to determine the student's perception of flipped and traditional teaching methods. Materials and Methods: In this analytical cross-sectional study, students attending medicine clinics were divided into two groups of roughly forty students each. One group received FC teaching and the other traditional lecture on hypo- and hyperthyroidism topics. A structured questionnaire on students' perception of FC teaching and traditional teaching technique was used for both groups. Different parameters related to the learning process about hypothyroidism and hyperthyroidism were considered as primary outcome variables. Coguide software was used for statistical analysis. Results: The students' age range was between 21 and 23 years. The majority were males (>55%). Among the students who attended FCs, the majority (>60%) agreed to follow the same method in future. Majority (>75%) of the students agreed that the reading materials were useful. Overall, a positive perception was observed in the FCs compared to that of the traditional classroom method. Conclusion: FC compared with traditional teaching methods had a good response from the medical students. Students' perception of FC method was positive.","PeriodicalId":32638,"journal":{"name":"Journal of Current Research in Scientific Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83492349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}